Aberrant lamellar body counts noted on the Beckman Coulter Unicel DxH 800Patrick B Kyle
Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Clin Chem Lab Med 50:1631-3. 2012
..Recently, significant imprecision was noted during LBC validation on the Beckman Coulter Unicel DxH 800...
- Reactivity of commercial benzodiazepine immunoassays to phenazepam
Patrick B Kyle
Department of Pathology, University of Mississippi Medical Center, Jackson, MS, USA
J Anal Toxicol 36:207-9. 2012
..Laboratorians and clinicians should be confident that phenazepam will be detected via most commercial drugs of abuse screens in patients after significant ingestion...
Illicit bath salts: not for bathingPatrick B Kyle
Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA
J Miss State Med Assoc 52:375-7. 2011
..Although recently outlawed, abuse of these products continues to occur in Mississippi...
- Drugs detected in suspected pediatric ingestions: a three-year review
Patrick B Kyle
Analytical Toxicology Laboratory, Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA
J Miss State Med Assoc 45:35-40. 2004
..This review shows that comprehensive toxicology testing provides the clinician significantly more information regarding the exposure of the pediatric patient presenting with an unknown chemical ingestion...
Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depressionBernadeta Szewczyk
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
Int J Neuropsychopharmacol 13:1089-101. 2010
..These data may also suggest that reductions in Freud-1 protein expression in the PFC may be associated with early onset of MDD...
- Domestic abuse of the European rave drug prolintane
Patrick B Kyle
Department of Pathology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
J Anal Toxicol 31:415-8. 2007
..The medical and scientific communities should be aware of the potential for prolintane abuse because it may cause symptoms similar to those of the amphetamines but is not likely to be detected by a routine urine drug screen...
- Suspected pediatric ingestions: effectiveness of immunoassay screens vs. gas chromatography/mass spectroscopy in the detection of drugs and chemicals
Patrick B Kyle
Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
J Toxicol Clin Toxicol 41:919-25. 2003
..This study shows that analysis by GC/MS offers the clinician a more comprehensive view into the exposure of the pediatric patient presenting with an unknown chemical ingestion...
- The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function
Meng-Yang Zhu
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
Neurochem Res 29:419-27. 2004
..The retention and slow diffusion of DMI and nisoxetine from membranes may contribute to their pharmacological and modulatory action on NET...
- Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression
Anteneh M Feyissa
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA
Prog Neuropsychopharmacol Biol Psychiatry 34:279-83. 2010
..This observation is consistent with reports showing that mGluR2/3 antagonists exhibit antidepressant-like activity in animal models and demonstrates that these receptors are promising targets for the discovery of novel antidepressants...
