Research Topics
Genomes and GenesSpecies | Mohammad Z HaiderSummaryAffiliation: Kuwait University Country: Kuwait Publications
| Collaborators
|
Detail Information
Publications
Influence of consanguinity and IgE receptor genotypes on clinical manifestations of asthma in Kuwaiti childrenZ Hijazi
Department of Paediatrics, Faculty of Medicine, Kuwait University
J Trop Pediatr 47:13-6. 2001..018). Our data suggest an equal maternal and paternal contribution to the inheritance of asthma and an association of the homozygous variant (Leu 181/Leu 183) of the IgE receptor FcepsilonRIbeta with disease severity...- HLA-DRB1 alleles in Hb SS patients with avascular necrosis of the femoral headA Adekile
Department of Paediatrics, Faculty of Medicine, Kuwait University, Kuwait
Am J Hematol 79:8-10. 2005..No significant differences in the allele frequencies in the SS patients with or without AVNFH were observed. It therefore appears that the HLA-DRB1 locus does not play a significant role in the pathogenesis of AVNFH Kuwaiti patients... - A C597-->A polymorphism in the Norrie disease gene is associated with advanced retinopathy of prematurity in premature Kuwaiti infantsM Z Haider
Paediatrics Department, Faculty of Medicine, Kuwait University, Safat, Kuwait
J Biomed Sci 9:365-70. 2002..In the case of the C110G mutation in the ND gene, no significant differences were detected between the controls and ROP cases, and the majority of subjects had a CC genotype in all three groups... - Gene deletion patterns in spinal muscular atrophy patients with different clinical phenotypesM Z Haider
Paediatrics Department, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
J Biomed Sci 8:191-6. 2001..The incidence of a second polymorphism in SMN gene exon 8 (presence of the sequence ATGGCCT) was markedly different in our population (97%) and those reported from Spain (50%) and Taiwan (0%)... - Human leukocyte antigen (HLA) DRB1 alleles in Kuwaiti Arabs with schizophreniaM Z Haider
Clinical Genetics Group, Pediatrics Department, Faculty of Medicine, Kuwait University of Kuwait, Kuwait
Am J Med Genet 96:870-2. 2000..For the remaining alleles, the differences between the two groups were not statistically significant. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:870-872, 2000... - Human leukocyte antigen-DQB1 alleles are not associated with schizophrenia in Kuwaiti ArabsMohammad Z Haider
Department of Pediatrics, Faculty of Medicine, Kuwait University and Hospital for Psychological Medicine, Kuwait
Psychiatry Clin Neurosci 58:236-9. 2004..The DQB1*0602 allele, which has been negatively associated in African-Americans in previous reports, was not detected in the present Kuwaiti schizophrenia patients or controls... - Angiotensin-converting enzyme gene insertion/deletion polymorphism in Kuwaiti children with retinopathy of prematurityM Z Haider
Paediatrics Department, Faculty of Medicine, Kuwait University, Kuwait
Biol Neonate 82:84-8. 2002..04). The incidences of ID and II genotypes were not significantly different amongst the 2 subgroups of ROP patients... - No evidence for an association between the 5-hydroxytryptamine 5-HT2a receptor gene and schizophrenia in Kuwaiti ArabsMohammad Z Haider
Clinical Genetics Group, Pediatrics Department, Kuwait University and Hospital for Psychological Medicine, Kuwait
Psychiatry Clin Neurosci 56:465-7. 2002.... - Prevalence of human leukocyte antigen DQA1 and DQB1 alleles in Kuwaiti Arab children with type 1 diabetes mellitusM Z Haider
Pediatrics Department, Faculty of Medicine, Kuwait University, Safat
Clin Genet 56:450-6. 1999..Analysis of HLA-DQBI/DQA1 haplotypes from IDDM cases and controls revealed a significantly high frequency of haplotype DQA1*0301/DQB1*0201 between Kuwaiti IDDM cases (49/78, 63%) and the controls (8/57, 14%)... - Missense mutations in norrie disease gene are not associated with advanced stages of retinopathy of prematurity in Kuwaiti arabsM Z Haider
Pediatrics Department, Faculty of Medicine, Kuwait University, Safat, Kuwait
Biol Neonate 77:88-91. 2000..We did not find an association between the presence or absence of missense mutations of the ND gene and the risk of severe ROP... - Screening 25 dystrophin gene exons for deletions in Arab children with Duchenne muscular dystrophyM Z Haider
Paediatrics Department, Faculty of Medicine Kuwait University, Safat
Hum Hered 48:61-6. 1998..This study, the first in an Arab population and only the second to use three PCR multiplex sets, documents one of the highest deletion detection rates in DMD... - Retinopathy of prematurity: mutations in the Norrie disease gene and the risk of progression to advanced stagesM Z Haider
Pediatrics Department, Faculty of Medicine, Kuwait University, Jabriya
Pediatr Int 43:120-3. 2001..Missense mutations in the Norrie disease (ND) gene have been associated with the risk of progression to advanced stages in cases of ROP from the US and also in clinically similar ND and familial exudative vitreoretinopathy... - Angiotensin-converting enzyme gene polymorphism and lipid profiles in Kuwaiti children with type 1 diabetesM Alsaeid
Department of Paediatrics, Faculty of Medicine, Kuwait University, Safat, Kuwait
Pediatr Diabetes 5:87-94. 2004.... - Influence of alpha-thalassemia trait on spleen function in sickle cell anemia patients with high HbFA D Adekile
Department of Pediatrics, Faculty of Medicine, Kuwait University
Am J Hematol 53:1-5. 1996..0%; however, the frequencies in Groups I, II, and III were 57.1, 30.0, and 18.8%, respectively. alpha-Thalassemia trait, therefore, appears to be associated with normal splenic function in these patients... - Role of human leukocyte antigen DRB1*0307 and DRB1*0308 in susceptibility to juvenile rheumatoid arthritisK M Alsaeid
Kuwait University, Faculty of Medicine, Pediatrics Department, PO Box 24923, Safat 13110, Kuwait
Clin Exp Rheumatol 21:399-402. 2003..To study the prevalence of Human Leukocyte Antigen (HLA) DR alleles in children with juvenile rheumatoid arthritis (JRA)... - Prevalence of angiotensin-converting enzyme gene insertion-deletion polymorphism in patients with primary knee osteoarthritisD K Shehab
Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait
Clin Exp Rheumatol 26:305-10. 2008.... - Angiotensin-converting enzyme gene polymorphism in Kuwaiti patients with systemic lupus erythematosusA M Al-Awadhi
Department of Medicine, Faculty of Medicine, Health Sciences Center, Kuwait University, and Rheumatic Disease Unit, Al Amiri Hospital, Kuwait
Clin Exp Rheumatol 25:437-42. 2007.... - Association of angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism with spondylarthropathiesDiaa K Shehab
Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait
J Biomed Sci 15:61-7. 2008..036). This study showed a significant association of the I-allele of ACE gene I/D polymorphism with spondylarthropathy in Kuwaiti Arabs... - Significant association of insertion/deletion polymorphism of the angiotensin-converting enzyme gene with rheumatoid arthritisSukhbir S Uppal
Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait
J Rheumatol 34:2395-9. 2007..Since plasma and tissue levels of ACE are determined at the transcriptional level, we test the hypothesis that the genotype of ACE in RA patients may be a determining factor in pathogenesis... - The prevalence of human leukocyte antigen (HLA) DR/DQ/DP alleles in Kuwaiti children with oligoarticular juvenile idiopathic arthritisK Alsaeid
Department of Pediatrics, Faculty of Medicine, Kuwait University, PO Box 24923, Safat, 13110, Kuwait
Rheumatol Int 26:224-8. 2006..007 respectively). In the case of DPB1, only one allele (*0101) was associated with OA-JIA (P<0.001). Most Kuwaiti Arab patients with OA-JIA who carried a DQ or DP susceptibility allele also had an accompanying DRB1*03 or *8 allele... - Pulmonary function studies in Kuwaiti children with sickle cell disease and elevated Hb FZ Hijazi
Department of Pediatrics, Kuwait University, Safat 13110, Kuwait
Int J Clin Pract 59:163-7. 2005..This observation underscores the early occurrence of pulmonary involvement, even in patients with an otherwise relatively mild SCD... 
Are 25(OH)D levels related to the severity of knee osteoarthritis and function?Khaled F al-Jarallah
Department of Medicine, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
Med Princ Pract 21:74-8. 2012..To investigate the effect of 25-hydroxyvitamin D [25(OH)D] in Kuwaiti patients with primary knee osteoarthritis (OA) and to assess its relation with radiological grading and functional status...- High frequency of HLA-DQB1 non-Asp(57) alleles in Kuwaiti children with insulin-dependent diabetes mellitusM Z Haider
Paediatrics Department, Faculty of Medicine, Kuwait University
Hum Hered 50:242-6. 2000..Our data report one of the highest frequency of NA/NA residues at this locus compared with that from different world populations (Sardinians, Norwegians, US Caucasians, US Blacks and Chinese)... - Th1 and Th2 cytokine profiles in sickle cell diseaseR Raghupathy
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
Acta Haematol 103:197-202. 2000..However, SS patients with good splenic function showed a relative Th1 bias, which may be an additional explanation for the protection against bacterial infections in such patients... - HLA-DRB1 alleles in Kuwaiti children with idiopathic nephrotic syndromeA A Al-Eisa
Pediatric Department, Faculty of Medicine, Kuwait University, Safat
Pediatr Nephrol 15:79-81. 2000..Our data highlight the role of the DRB 1*0701 allele in predisposing Kuwaiti Arab children with idiopathic nephrotic syndrome to a more prolonged course of the disease... - Influence of alpha-thalassemia trait on the prevalence and severity of anemia in pregnancy among women in KuwaitF M Diejomaoh
Department of Obstetrics and Gynecology, Faculty of Medicine, Kuwait University, Safat, Kuwait
Acta Haematol 104:92-4. 2000..We, therefore, conclude that while the alpha-thal trait affects the prevalence of anemia among pregnant Kuwaiti women, it does not affect its severity... - Silent brain infarcts are rare in Kuwaiti children with sickle cell disease and high Hb FA D Adekile
Department of Pediatrics, Faculty of Medicine, Kuwait University, Safat, Kuwait
Am J Hematol 70:228-31. 2002..3%. Silent brain infarcts are uncommon in our patients, and the protective factors remain to be fully elucidated... - Frequency of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patientsA D Adekile
Department of Pediatrics, Kuwait University, Kuwait
Am J Hematol 66:263-6. 2001..4%. The frequency was identical among those without osteonecrosis. Although the allele frequency is higher among our patients compared to American SS patients, our results do not suggest an association with osteonecrosis... - Avascular necrosis of the hip in children with sickle cell disease and high Hb F: magnetic resonance imaging findings and influence of alpha-thalassemia traitA D Adekile
Department of Pediatrics, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait
Acta Haematol 105:27-31. 2001.... - Angiotensin converting enzyme gene insertion/deletion polymorphism in idiopathic nephrotic syndrome in Kuwaiti Arab childrenA Al-Eisa
Paediatrics Department, Faculty of Medicine, Kuwait University, Kuwait
Scand J Urol Nephrol 35:239-42. 2001..We have investigated the association of ACE gene I/D polymorphism with the clinical presentation of idiopathic nephrotic syndrome (INS) in Kuwaiti children... - Prevalence of human leukocyte antigen (HLA) DRB1 alleles in Kuwaiti children with juvenile rheumatoid arthritisKhaled Alsaeid
Pediatrics Department, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
Eur J Immunogenet 29:1-5. 2002..Also, a non-significant increase in the frequency of the DRB1*04, *11 and *15 alleles was detected in the polyarticular subtype of the Kuwaiti JRA cases compared to the controls... - Temporal sequence of splenic dysfunction in sickle cell diseaseA D Adekile
Department of Pediatrics, Faculty of Medicine, Kuwait University
Am J Hematol 69:23-7. 2002..This finding may have significant implications for the clinical symptomatology and therapeutic strategies of sickle cell disease... 
Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary knee osteoarthritisKhaled F al-Jarallah
Department of Pediatrics, Kuwait University, Faculty of Medicine, Jabriya, Kuwait
Ann Saudi Med 31:35-9. 2011....- Avascular necrosis of the femoral head in adult Kuwaiti sickle cell disease patientsR Marouf
Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait
Acta Haematol 110:11-5. 2003..AVNFH is, indeed, quite common among Kuwaiti SCD patients and there is a need for early institution of preventive and therapeutic protocols... - Lack of an association between candidate gene loci and idiopathic generalized epilepsy in Kuwaiti Arab childrenM Z Haider
Department of Pediatrics, Faculty of Medicine, Kuwait University, PO Box 24923, Safat, 13110, Kuwait
J Biomed Sci 12:815-8. 2005..This is completely different from the findings reported from Caucasian populations of France, Australia and USA in which case a strong association has been reported between IGE and these genes... - Silent brain infarcts in adult Kuwaiti sickle cell disease patientsR Marouf
Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait
Am J Hematol 73:240-3. 2003..Further studies are needed to investigate the factors modulating this heterogeneity... - Systemic lupus erythematosus in Kuwaiti children: organ system involvement and serological findingsK Alsaeid
Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait
Lupus 13:613-7. 2004..The most significant finding in this study is the high frequency of hematological manifestations and the relatively low incidence of renal disease and neuropsychiatric abnormalities in Kuwaiti children with SLE...