M John Albert

Summary

Affiliation: Kuwait University
Country: Kuwait

Publications

  1. pmc Whole genome sequencing and comparative genomic analyses of two Vibrio cholerae O139 Bengal-specific Podoviruses to other N4-like phages reveal extensive genetic diversity
    Derrick E Fouts
    J Craig Venter Institute, Rockville, MD, USA
    Virol J 10:165. 2013
  2. pmc Oral immunization with cholera toxin provides protection against Campylobacter jejuni in an adult mouse intestinal colonization model
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    MBio 4:e00246-13. 2013
  3. pmc In vitro susceptibility of Campylobacter jejuni from Kuwait to tigecycline & other antimicrobial agents
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    Indian J Med Res 137:187-90. 2013
  4. pmc Induction of cytokines in different organs after intranasal inoculation of Campylobacter jejuni in mice
    Nadia A Al-Banna
    Department of Microbiology, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
    Gut Pathog 4:23. 2012
  5. pmc Application of protein purification methods for the enrichment of a cytotoxin from Campylobacter jejuni
    Xenia Gatsos
    Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria, Australia
    BMC Microbiol 12:303. 2012
  6. pmc The prevalence of antimicrobial resistance and carriage of virulence genes in Staphylococcus aureus isolated from food handlers in Kuwait City restaurants
    Edet E Udo
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    BMC Res Notes 2:108. 2009
  7. pmc Identification of a Campylobacter jejuni protein that cross-reacts with cholera toxin
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait
    Infect Immun 75:3070-3. 2007
  8. pmc Diarrhoeagenic Escherichia coli are not a significant cause of diarrhoea in hospitalised children in Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    BMC Microbiol 9:62. 2009
  9. pmc Genotypic characterization of rotaviruses and prevalence of serotype-specific serum antibodies in children in Kuwait
    R W Marmash
    Department of Microbiology, Kuwait University, Kuwait
    Epidemiol Infect 135:1331-7. 2007
  10. ncbi request reprint High prevalence and level of resistance to metronidazole, but lack of resistance to other antimicrobials in Helicobacter pylori, isolated from a multiracial population in Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    Aliment Pharmacol Ther 24:1359-66. 2006

Collaborators

Detail Information

Publications43

  1. pmc Whole genome sequencing and comparative genomic analyses of two Vibrio cholerae O139 Bengal-specific Podoviruses to other N4-like phages reveal extensive genetic diversity
    Derrick E Fouts
    J Craig Venter Institute, Rockville, MD, USA
    Virol J 10:165. 2013
    ..We aimed at a complete molecular characterization of both phages and elucidation of their genetic and structural differences and assessment of their genetic relatedness to the N4-like phage group...
  2. pmc Oral immunization with cholera toxin provides protection against Campylobacter jejuni in an adult mouse intestinal colonization model
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    MBio 4:e00246-13. 2013
    ..CT-B antibody cross-reacted with MOMP. Since CT-B is a component of oral cholera vaccines, it might be possible to control C. jejuni diarrhea with these vaccines...
  3. pmc In vitro susceptibility of Campylobacter jejuni from Kuwait to tigecycline & other antimicrobial agents
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    Indian J Med Res 137:187-90. 2013
    ....
  4. pmc Induction of cytokines in different organs after intranasal inoculation of Campylobacter jejuni in mice
    Nadia A Al-Banna
    Department of Microbiology, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
    Gut Pathog 4:23. 2012
    ..abstract:..
  5. pmc Application of protein purification methods for the enrichment of a cytotoxin from Campylobacter jejuni
    Xenia Gatsos
    Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria, Australia
    BMC Microbiol 12:303. 2012
    ..Our objective was to develop a method to enrich and thus partially characterise this cytotoxin, as a pathway to the eventual identification and characterisation of the toxin...
  6. pmc The prevalence of antimicrobial resistance and carriage of virulence genes in Staphylococcus aureus isolated from food handlers in Kuwait City restaurants
    Edet E Udo
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    BMC Res Notes 2:108. 2009
    ..aureus from food handlers in Kuwait restaurants justifying the screening of food handlers to detect and treat carriers and protect restaurant customers from staphylococcal food poisoning...
  7. pmc Identification of a Campylobacter jejuni protein that cross-reacts with cholera toxin
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait
    Infect Immun 75:3070-3. 2007
    ..Our results indicate that C. jejuni does not produce a functional CTLT, but the reactivity of PorA with CT antibody would lead to the erroneous conclusion that C. jejuni produces a functional CTLT...
  8. pmc Diarrhoeagenic Escherichia coli are not a significant cause of diarrhoea in hospitalised children in Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    BMC Microbiol 9:62. 2009
    ..coli colony pools...
  9. pmc Genotypic characterization of rotaviruses and prevalence of serotype-specific serum antibodies in children in Kuwait
    R W Marmash
    Department of Microbiology, Kuwait University, Kuwait
    Epidemiol Infect 135:1331-7. 2007
    ..These results show that G1 is the predominant serotype in Kuwait and that a vaccine that contains G1 will be most effective...
  10. ncbi request reprint High prevalence and level of resistance to metronidazole, but lack of resistance to other antimicrobials in Helicobacter pylori, isolated from a multiracial population in Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    Aliment Pharmacol Ther 24:1359-66. 2006
    ..The primary treatment regimen for Helicobacter pylori infection for Kuwaitis does not contain metronidazole, but that for expatriates does. There is also increasing failure of antimicrobial therapy...
  11. ncbi request reprint Cholera: time for action
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
    Indian J Med Res 123:15-6. 2006
  12. pmc Major outer membrane proteins from many Campylobacter species cross-react with cholera toxin
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    Clin Vaccine Immunol 15:859-62. 2008
    ..As with C. jejuni, this finding may lead to the erroneous conclusion that these additional species produce a functional CTLT. However, this common cross-reactive OMP can be explored as a vaccine candidate to prevent campylobacteriosis...
  13. pmc Cross-reactivity of outer membrane proteins of Campylobacter species with cholera toxin
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    Indian J Med Res 133:207-11. 2011
    ..The cross-reactivity of PorAs of Campylobacter species with CT may lead to the erroneous conclusion that Campylobacter species produce a functional CTLT...
  14. doi request reprint Tetracycline resistance is frequent among Campylobacter jejuni isolates from Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Microb Drug Resist 15:115-20. 2009
    ..We conclude that tetracycline resistance is a feature of C. jejuni in Kuwait as in other parts of the world and that empirical therapy with tetracycline will yield variable results in Kuwait...
  15. pmc Ciprofloxacin-resistant Salmonella enterica serovar typhi from Kuwait with novel mutations in gyrA and parC genes
    Tzonyo Dimitrov
    Department of Microbiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    J Clin Microbiol 47:208-11. 2009
    ..Both isolates had three novel gyrA mutations (55-Leu-->Trp, 87-Asp-->Ala, and 106-Gln-->Arg) and three novel parC mutations (84-Glu-->Lys, 106-Trp-->Gly, and 128-Tyr-->Asp)...
  16. doi request reprint Emergence of CTX-M-15 type extended-spectrum beta-lactamase-producing Salmonella spp. in Kuwait and the United Arab Emirates
    Vincent O Rotimi
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    J Med Microbiol 57:881-6. 2008
    ..This is of great concern as the gene is also found in association with the ISEcpI gene, which may easily facilitate its spread. These isolates originated mostly from non-Kuwaiti Arabs rather than from people of Asian origin...
  17. ncbi request reprint PorA protein of Campylobacter jejuni is not a cytotoxin mediating inflammatory diarrhoea
    Islam Khan
    Department of Biochemistry, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
    Microbes Infect 7:853-9. 2005
    ..Both cytotoxin-positive as well as cytotoxin-negative strains expressed PorA as determined by immunoblot analysis. These findings show that the porA gene product of C. jejuni is not a cytotoxin mediating inflammatory diarrhoea...
  18. pmc Recombinant PorA, the major outer membrane protein of Campylobacter jejuni, provides heterologous protection in an adult mouse intestinal colonization model
    Anjum Islam
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait
    Clin Vaccine Immunol 17:1666-71. 2010
    ..005), and 42% (for strain 111, P < 0.001) for the 9-day period compared to control mice given phosphate-buffered saline. Thus, PorA provided appreciable protection against colonization with heterologous serotypes...
  19. doi request reprint Increasing prevalence of antimicrobial resistance in Streptococcus pneumoniae in Kuwait: implications for therapy
    Eiman M Mokaddas
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    Microb Drug Resist 13:227-33. 2007
    ..These data are unique because they are representative of the whole Kuwaiti population...
  20. ncbi request reprint Ciprofloxacin resistance and its molecular mechanism in Campylobacter spp. isolated in Kuwait
    M John Albert
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Microb Drug Resist 11:266-70. 2005
    ..Thus, ciprofloxacin is of limited use for treatment in Kuwait and MAMA PCR is a useful assay to study gyrA mutation. Because Kuwait has a large expatriate population of workers, it can be a focus of spread of antimicrobial resistance...
  21. doi request reprint Impact of pneumococcal conjugate vaccines on burden of invasive pneumococcal disease and serotype distribution of Streptococcus pneumoniae isolates: an overview from Kuwait
    Eiman Mokaddas
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    Vaccine 30:G37-40. 2012
    ..In conclusion, with the emergence of new pneumococcal serotypes, broader vaccine coverage will aid in the prevention of IPD in children...
  22. pmc Correlation of proinflammatory and anti-inflammatory cytokine levels with histopathological changes in an adult mouse lung model of Campylobacter jejuni infection
    Nadia Al-Banna
    Department of Microbiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    Clin Vaccine Immunol 15:1780-7. 2008
    ..This model is useful for further studies of the pathogenesis of C. jejuni infection and vaccine evaluation...
  23. doi request reprint High prevalence of VIM-4 and NDM-1 metallo-β-lactamase among carbapenem-resistant Enterobacteriaceae
    Wafaa Jamal
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    J Med Microbiol 62:1239-44. 2013
    ..The VIM-4 gene was not transferable by conjugation studies of six selected strains. We demonstrated here the emergence of VIM-4- and NDM-1-producing isolates in the largest teaching hospital in Kuwait. ..
  24. ncbi request reprint Emergence of multidrug-resistant Salmonella spp. and isolates with reduced susceptibility to ciprofloxacin in Kuwait and the United Arab Emirates
    Vincent O Rotimi
    Department of Microbiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    Diagn Microbiol Infect Dis 60:71-7. 2008
    ..7% Salmonella paratyphi. Salmonella spp. with reduced quinolones susceptibility have emerged in the Gulf region, and this is of concern as it may compromise the treatment of infections caused by invasive strains...
  25. doi request reprint Histopathological and ultrastructural studies of a mouse lung model of Campylobacter jejuni infection
    Nadia A Al-Banna
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    J Med Microbiol 57:210-7. 2008
    ..This characterization of pathology should contribute to a better understanding of the animal model and pathogenesis of C. jejuni infection...
  26. pmc Implications of Streptococcus pneumoniae penicillin resistance and serotype distribution in Kuwait for disease treatment and prevention
    Eiman M Mokaddas
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    Clin Vaccine Immunol 15:203-7. 2008
    ....
  27. doi request reprint Different norovirus genotypes in patients with gastroenteritis in Kuwait
    Amirah Al-Rashidi
    Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait
    J Med Virol 85:1611-8. 2013
    ..12, GII.b, GII.3, GII.8, and GII.7. This study highlights the importance of screening for norovirus infection in acute gastroenteritis and having a reporting system to understand better the epidemiology of norovirus infection in Kuwait...
  28. pmc Erythema nodosum and bilateral breast abscesses due to Salmonella enterica serotype Poona
    Khalifa Al Benwan
    Department of Microbiology, Al Amiri Hospital, Sharq, Kuwait
    J Clin Microbiol 48:3786-7. 2010
    ..This is the first reported case of erythema nodosum presumably associated with Salmonella infection without a gastrointestinal manifestation...
  29. pmc Cystitis caused by Aeromonas caviae
    Khalifa Al-Benwan
    Department of Microbiology, Al Amiri Hospital, Kuwait City, Kuwait
    J Clin Microbiol 45:2348-50. 2007
    ..We report for the first time a case of urinary tract infection caused by A. caviae in an adult patient with a history of increased frequency of urination, dysuria, hematuria, and weight loss...
  30. ncbi request reprint Aeromonas hydrophila subsp. dhakensis subsp. nov., isolated from children with diarrhoea in Bangladesh, and extended description of Aeromonas hydrophila subsp. hydrophila (Chester 1901) Stanier 1943 (approved lists 1980)
    Geert Huys
    Laboratory of Microbiology, Ghent University, Belgium
    Int J Syst Evol Microbiol 52:705-12. 2002
    ..dhakensis subsp. nov. is proposed. Its type strain is P21T (= LMG 19562T= CCUG 45377T). An extended description of A. hydrophila subsp. hydrophila (Chester 1901) Stanier 1943 (Approved Lists 1980) is given...
  31. pmc DNA-level characterization of Helicobacter pylori strains from patients with overt disease and with benign infections in Bangladesh
    Motiur Rahman
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    J Clin Microbiol 41:2008-14. 2003
    ..Phylogenetic analysis of the vacA middle region and the 5' end of the cagA gene indicates that Bangladeshi isolates are more closely related to H. pylori isolates from India and are different from isolates from East Asia...
  32. pmc Critical factors influencing the occurrence of Vibrio cholerae in the environment of Bangladesh
    Anwar Huq
    Center of Marine Biotechnology, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA
    Appl Environ Microbiol 71:4645-54. 2005
    ..g., plankton population blooms. The new information on the ecology of V. cholerae is proving useful in developing environmental models for the prediction of cholera epidemics...
  33. doi request reprint Filamentous vibriophage fs2 encoding the rstC gene integrates into the same chromosomal region as the CTX phage [corrected]
    Dong Tu Nguyen
    Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
    FEMS Microbiol Lett 284:225-30. 2008
    ..cholerae O1 and O139. When infected with fs2, a fimbriate strain of V. cholerae O1 appeared to reduce fimbrial production in an adult rabbit ileal loop assay...
  34. pmc Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones
    Tran Thuy Chau
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Ho Chi Minh City, Vietnam
    Antimicrob Agents Chemother 51:4315-23. 2007
    ..The 8-methoxy fluoroquinolone gatifloxacin showed rapid killing of serovar Typhi harboring both the single- and double-amino-acid substitutions...
  35. pmc A study of typhoid fever in five Asian countries: disease burden and implications for controls
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 86:260-8. 2008
    ..To inform policy-makers about introduction of preventive interventions against typhoid, including vaccination...
  36. ncbi request reprint Lack of polymorphism in a Vibrio cholerae O139-specific DNA region encoding the somatic antigen in strains isolated during 1993-1998
    Susanna Falklind-Jerkérus
    Karolinska Institute, Department of Microbiology, Pathology and Immunology, Division of Clinical Bacteriology, Huddinge University Hospital, Stockholm, Sweden
    Int J Med Microbiol 292:505-11. 2003
    ..The isolates of later years diverged exhibiting different patterns by pulsed-field gel electrophoresis (PFGE), and becoming susceptible to TMP-SMX and O/129, and CAMP-haemolysin negative...
  37. ncbi request reprint Supplementation with zinc, but not vitamin A, improves seroconversion to vibriocidal antibody in children given an oral cholera vaccine
    M John Albert
    International Centre for Diarrhoeal Disease Research, Bangladesh
    J Infect Dis 187:909-13. 2003
    ..Thus, supplementation with zinc improves seroconversion to vibriocidal antibody and, hence, has the potential to improve the efficacy of oral cholera vaccine in children...
  38. ncbi request reprint Isolation and characterization of provisional serovar Shigella boydii E16553 from diarrhoeal patients in Bangladesh
    M Ansaruzzaman
    International Center for Diarrhoeal Disease Research, Bangladesh, Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
    J Med Microbiol 54:477-80. 2005
    ..boydii 19...
  39. ncbi request reprint Aetiology of diarrhoea in a birth cohort of children aged 0-2 year(s) in rural Mirzapur, Bangladesh
    Khundkar Z Hasan
    Public Health Sciences Division, ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
    J Health Popul Nutr 24:25-35. 2006
    ..Enterotoxigenic B. fragilis was also identified as a pathogen. Ongoing vaccine efforts focusing on Shigella, rotavirus, and ETEC would be useful...
  40. ncbi request reprint Suppressive effect of zinc on antibody response to cholera toxin in children given the killed, B subunit-whole cell, oral cholera vaccine
    Firdausi Qadri
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Vaccine 22:416-21. 2004
    ..Thus, zinc enhanced vibriocidal antibody response, but suppressed CT-antibody response, suggesting that zinc supplementation has different modulating effects on vibriocidal antibody response and CT-antibody response...
  41. ncbi request reprint Vibrio cholerae (non-O1, non-O139) sepsis in a child with Fanconi anemia
    Rita Dhar
    Department of Laboratories, Al Adan Hospital, Hadiya, Kuwait
    Diagn Microbiol Infect Dis 50:287-9. 2004
    ..To our knowledge, this is the first case of V. cholerae (non-O1, non-O139) septicemia associated with Fanconi anemia...
  42. ncbi request reprint SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD
    Colin B O'Connell
    Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 1192, USA
    Mol Microbiol 52:1613-25. 2004
    ..Together, these results demonstrate that SepL has a unique role in type III secretion as a functional component of the translocation system that interacts with an essential element of the secretion machinery...
  43. ncbi request reprint The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia
    Camilo J Acosta
    International Vaccine Institute, Seoul, Republic of Korea
    J Health Popul Nutr 22:240-5. 2004
    ..Epidemiological studies contribute to all stages of development of vaccine evaluation and introduction...