G A Kurian

Summary

Publications

  1. doi request reprint Methanol extract of Desmodium gangeticum roots preserves mitochondrial respiratory enzymes, protecting rat heart against oxidative stress induced by reperfusion injury
    Gino A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 37, India
    J Pharm Pharmacol 60:523-30. 2008
  2. pmc Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury
    G A Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613 402, India
    Indian J Pharm Sci 72:745-52. 2010
  3. pmc A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract
    Ga Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur, Tamil Nadu 613 402, India
    J Young Pharm 2:156-61. 2010
  4. doi request reprint Energy status determines the distinct biochemical and physiological behavior of interfibrillar and sub-sarcolemmal mitochondria
    Gino A Kurian
    Department of Cellular Biochemistry and Human Genetics, The Hebrew University Hadassah Schools of Medicine and Dental Medicine, Ein Kerem, Jerusalem, Israel
    Biochem Biophys Res Commun 428:376-82. 2012
  5. doi request reprint Rat cardiac mitochondrial sub-populations show distinct features of oxidative phosphorylation during ischemia, reperfusion and ischemic preconditioning
    Gino A Kurian
    Department of Cellular Biochemistry and Human Genetics, The Hebrew University Hadassah Schools of Medicine and Dental Medicine, Jerusalem, Israel
    Cell Physiol Biochem 30:83-94. 2012
  6. doi request reprint Methanol extract of Desmodium gangeticum DC root mimetic post-conditioning effect in isolated perfused rat heart by stimulating muscarinic receptors
    Gino A Kurian
    Medical Biochemistry, School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamil Nadu, India
    Asian Pac J Trop Med 5:448-54. 2012
  7. ncbi request reprint N-acetylcysteine and magnesium improve biochemical abnormalities associated with myocardial ischaemic reperfusion in South Indian patients undergoing coronary artery bypass grafting: a comparative analysis
    G A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 600037, India
    Singapore Med J 51:381-8. 2010
  8. pmc Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts
    Gino A Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur, Tamil Nadu, India
    Chin Med 5:3. 2010
  9. ncbi request reprint Administration of aqueous extract of Desmodium gangeticum (L) root protects rat heart against ischemic reperfusion injury induced oxidative stress
    Gino A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 600 037, India
    Indian J Exp Biol 47:129-35. 2009
  10. ncbi request reprint Effect of aqueous extract of the Desmodium gangeticum DC root in the severity of myocardial infarction
    Gino A Kurian
    BITS Training Center, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 50, India
    J Ethnopharmacol 97:457-61. 2005

Collaborators

Detail Information

Publications11

  1. doi request reprint Methanol extract of Desmodium gangeticum roots preserves mitochondrial respiratory enzymes, protecting rat heart against oxidative stress induced by reperfusion injury
    Gino A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 37, India
    J Pharm Pharmacol 60:523-30. 2008
    ....
  2. pmc Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury
    G A Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613 402, India
    Indian J Pharm Sci 72:745-52. 2010
    ..These results suggest that Desmodium gangeticum aqueous root extract can preserve the mitochondrial and sarcoplasmic ATPase in the myocardium, resulting in the improvement of cardiac function after ischemia reperfusion injury...
  3. pmc A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract
    Ga Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur, Tamil Nadu 613 402, India
    J Young Pharm 2:156-61. 2010
    ....
  4. doi request reprint Energy status determines the distinct biochemical and physiological behavior of interfibrillar and sub-sarcolemmal mitochondria
    Gino A Kurian
    Department of Cellular Biochemistry and Human Genetics, The Hebrew University Hadassah Schools of Medicine and Dental Medicine, Ein Kerem, Jerusalem, Israel
    Biochem Biophys Res Commun 428:376-82. 2012
    ..The distinct physiological-biochemical functions of the mitochondrial sub-populations during ischemia and reperfusion depend on the overall energy status of the mitochondrial sub-population...
  5. doi request reprint Rat cardiac mitochondrial sub-populations show distinct features of oxidative phosphorylation during ischemia, reperfusion and ischemic preconditioning
    Gino A Kurian
    Department of Cellular Biochemistry and Human Genetics, The Hebrew University Hadassah Schools of Medicine and Dental Medicine, Jerusalem, Israel
    Cell Physiol Biochem 30:83-94. 2012
    ..This study was undertaken to compare functional oxidative phosphorylation (OXPHOS) in IFM and SSM during ischemia, reperfusion and ischemic preconditioning...
  6. doi request reprint Methanol extract of Desmodium gangeticum DC root mimetic post-conditioning effect in isolated perfused rat heart by stimulating muscarinic receptors
    Gino A Kurian
    Medical Biochemistry, School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamil Nadu, India
    Asian Pac J Trop Med 5:448-54. 2012
    ..To evaluate pharmacological mimetic action of herbal extract Desmodium gangeticum (DG) roots on ischemia reperfusion injury...
  7. ncbi request reprint N-acetylcysteine and magnesium improve biochemical abnormalities associated with myocardial ischaemic reperfusion in South Indian patients undergoing coronary artery bypass grafting: a comparative analysis
    G A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 600037, India
    Singapore Med J 51:381-8. 2010
    ..The limited clinical success of anti-ischaemic reperfusion agents has prompted a comparison of the efficacy of N-acetylcysteine (NAC) and magnesium (Mg) in South Indian patients undergoing coronary artery bypass grafting (CABG)...
  8. pmc Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts
    Gino A Kurian
    School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur, Tamil Nadu, India
    Chin Med 5:3. 2010
    ..CONCLUSION: The ethyl acetate extract of Desmodium gangeticum root protects the myocardium against ischemia-reperfusion-induced damage in rats. The effects of the extract may be related to the inhibition of lipid peroxidation...
  9. ncbi request reprint Administration of aqueous extract of Desmodium gangeticum (L) root protects rat heart against ischemic reperfusion injury induced oxidative stress
    Gino A Kurian
    MMM Academy of Medical Sciences, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 600 037, India
    Indian J Exp Biol 47:129-35. 2009
    ..These results indicate that DG improves the antioxidant capacity of heart and attenuate the degree of lipid peroxidation after IR...
  10. ncbi request reprint Effect of aqueous extract of the Desmodium gangeticum DC root in the severity of myocardial infarction
    Gino A Kurian
    BITS Training Center, Institute of Cardiovascular Diseases, Madras Medical Mission, 4A Jayalalithanagar, Mogappair, Chennai 50, India
    J Ethnopharmacol 97:457-61. 2005
    ....
  11. ncbi request reprint Antioxidant status of South Indian patients undergoing coronary artery bypass graft surgery: a role of intra operative magnesium supplementation
    Gino A Kurian
    Int J Cardiol 128:139-41. 2008
    ..However, the extensive treatment of the patients with magnesium influences the cellular response to ischemia and thus induces cardio-protection against oxidative stress...