G C Kundu

Summary

Publications

  1. ncbi Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells
    Priyanka Sharma
    National Center for Cell Science, Pune, India
    Mol Cancer 9:178. 2010
  2. ncbi Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells
    Mansoor Ahmed
    National Center for Cell Science NCCS, NCCS Complex, Pune 411 007, India
    Mol Cancer 9:101. 2010
  3. ncbi Uteroglobin binding proteins: regulation of cellular motility and invasion in normal and cancer cells
    G C Kundu
    Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Ann N Y Acad Sci 923:234-48. 2000
  4. ncbi Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice
    F Zheng
    Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Nat Med 5:1018-25. 1999
  5. ncbi Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells
    S Philip
    National Center for Cell Science, NCCS Complex, Pune 411 007, India
    J Biol Chem 276:44926-35. 2001
  6. ncbi Uteroglobin: physiological role in normal glomerular function uncovered by targeted disruption of the uteroglobin gene in mice
    A B Mukherjee
    Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892 1830, USA
    Am J Kidney Dis 32:1106-20. 1998
  7. ncbi Uteroglobin: a novel cytokine?
    A B Mukherjee
    Section on Developmental Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Cell Mol Life Sci 55:771-87. 1999
  8. ncbi Severe fibronectin-deposit renal glomerular disease in mice lacking uteroglobin
    Z Zhang
    Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development NICHD, National Insitutes of Health NIH, Bethesda, MD 20892 1830, USA
    Science 276:1408-12. 1997

Collaborators

Detail Information

Publications8

  1. ncbi Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells
    Priyanka Sharma
    National Center for Cell Science, Pune, India
    Mol Cancer 9:178. 2010
    ..To investigate the effects of TSA on OPN transcription, we analyzed a proximal segment of OPN promoter in cervical carcinoma cells...
  2. ncbi Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells
    Mansoor Ahmed
    National Center for Cell Science NCCS, NCCS Complex, Pune 411 007, India
    Mol Cancer 9:101. 2010
    ....
  3. ncbi Uteroglobin binding proteins: regulation of cellular motility and invasion in normal and cancer cells
    G C Kundu
    Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Ann N Y Acad Sci 923:234-48. 2000
    ..Taken together, our data define receptor-mediated functions of UG in which this protein regulates vital cellular functions by both autocrine and paracrine pathways...
  4. ncbi Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice
    F Zheng
    Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Nat Med 5:1018-25. 1999
    ..These results define an essential role for UG in preventing mouse IgA nephropathy and warrant further studies to determine if a similar mechanism(s) underlies the human disease...
  5. ncbi Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells
    S Philip
    National Center for Cell Science, NCCS Complex, Pune 411 007, India
    J Biol Chem 276:44926-35. 2001
    ....
  6. ncbi Uteroglobin: physiological role in normal glomerular function uncovered by targeted disruption of the uteroglobin gene in mice
    A B Mukherjee
    Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892 1830, USA
    Am J Kidney Dis 32:1106-20. 1998
    ..Nevertheless, the UG gene-knockout mice provide a valuable animal model for investigation of human glomerulopathies in general and familial Fn-deposit glomerulopathy in particular...
  7. ncbi Uteroglobin: a novel cytokine?
    A B Mukherjee
    Section on Developmental Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
    Cell Mol Life Sci 55:771-87. 1999
    ..Molecular characterization of the UG receptor and signal transduction via this receptor pathway may show that this protein belongs to a novel cytokine/chemokine family...
  8. ncbi Severe fibronectin-deposit renal glomerular disease in mice lacking uteroglobin
    Z Zhang
    Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development NICHD, National Insitutes of Health NIH, Bethesda, MD 20892 1830, USA
    Science 276:1408-12. 1997
    ..Thus, UG is essential for maintaining normal renal function in mice, which raises the possibility that an analogous pathogenic mechanism may underlie genetic Fn-deposit human glomerular disease...