Dinesh Kumar

Summary

Affiliation: Indian Veterinary Research Institute
Location: Izatnagar, Bareilly (U.P.), India
Publications:
1. Antihyperalgesic and Anti-inflammatory Effects of Atorvastatin in Chronic Constriction Injury-Induced Neuropathic Pain in Rats.
Pathak NN
Inflammation. 2013 Jul 20. [Epub ahead of print]

2. Topical pluronic F-127 gel application enhances cutaneous wound healing in rats.
Kant V
Acta Histochem. 2013 May 23.

3. Topically applied substance P enhanced healing of open excision wound in rats.
Kant V
Eur J Pharmacol. 2013 May 15.

4. Anti-inflammatory and antipyretic activities of the ethanolic extract of Shorea robusta Gaertn. f. resin.
Wani TA
Indian J Biochem Biophys. 2012 Dec;49(6):463-7.

5. Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy.
More AS
Pharmacol Biochem Behav. 2013 Feb;103(4):764-72.

6. Analgesic activity of the ethanolic extract of Shorea robusta resin in experimental animals.
Wani TA
Indian J Pharmacol. 2012 Jul-Aug;44(4):493-9.

7. Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat.
More AS
Naunyn Schmiedebergs Arch Pharmacol. 2012 Nov;385(11):1127-39.

8. Wound healing activity of ethanolic extract of Shorea robusta Gaertn. f. resin.
Wani TA
Indian J Exp Biol. 2012 Apr;50(4):277-81.

9. Res Vet Sci. 2012 Aug;93(1):296-9.
Oxidant/antioxidant balance, minerals status and apoptosis in peripheral blood of dogs naturally infected with Dirofilaria immitis.
Dimri U

10. Wound healing activity of carbon monoxide liberated from CO-releasing molecule (CO-RM).
Ahanger AA
Naunyn Schmiedebergs Arch Pharmacol. 2011 Jul;384(1):93-102.

11. Pro-healing potential of hemin: an inducer of heme oxygenase-1.
Ahanger AA
Eur J Pharmacol. 2010 Oct 25;645(1-3):165-70.

12. Evaluation of autologous bone marrow-derived nucleated cells for healing of full-thickness skin wounds in rabbits.
Borena BM
Int Wound J. 2010 Aug;7(4):249-60.

13. Autologous bone marrow-derived cells for healing excisional dermal wounds of rabbits.
Borena BM
Vet Rec. 2009 Nov 7;165(19):563-8.

14. Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat.
ArunaDevi R
Nitric Oxide. 2010 Jan 1;22(1):1-10.

15. Neuroprotective effect of 5,7,3',4',5'-pentahydroxy dihydroflavanol-3-O-(2''-O-galloyl)-beta-D-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat.
ArunaDevi R
Eur J Pharmacol. 2010 Jan 25;626(2-3):205-12.

16. Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica.
Singh TU,
Exp Parasitol. 2009 Dec;123(4):302-8.

17. Effects of amino acid neurotransmitters on spontaneous muscular activity of the rumen amphistome, Gastrothylax crumenifer.
Verma PK
J Helminthol. 2009 Dec;83(4):385-9.

18. Functional role of cholinergic drugs on spontaneous muscular activity in the amphistome Gastrothylax crumenifer from ruminants.
Verma PK
J Helminthol. 2009 Mar;83(1):77-82.

19. Increased hyperalgesia by 5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats.
Ramteke VD
Pharmacol Biochem Behav. 2009 Jan;91(3):417-22.

20. Role of nitric oxide and carbon monoxide in N(omega)-Nitro-L-arginine methyl ester-resistant acetylcholine-induced relaxation in chicken carotid artery.
Leo MD
Eur J Pharmacol. 2008 Oct 31;596(1-3):111-7.

21. Paralytic effect of alcoholic extract of Allium sativum and Piper longum on liver amphistome, Gigantocotyle explanatum.
Singh TU
Indian J Pharmacol. 2008 Mar;40(2):64-8.

22. The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study.
Bhat AS
Anesth Analg. 2008 Mar;106(3):978-84.

23. Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats.
Dudhgaonkar SP
Inflammopharmacology. 2007 Oct;15(5):188-95.

24. Synergistic interaction between meloxicam and aminoguanidine in formalin-induced nociception in mice.
Dudhgaonkar SP
Eur J Pain. 2008 Apr;12(3):321-8.

25. Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in adjuvant-induced arthritis in female albino rats: an isobolographic study.
Bhat AS
Eur J Pharmacol. 2007 Feb 5;556(1-3):190-9.

26. Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
Dudhgaonkar SP
Eur J Pain. 2007 Jul;11(5):528-34.

27. Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
Naik AK
Eur J Pharmacol. 2006 Jan 13;530(1-2):59-69.

28. Role of oxidative stress in pathophysiology of peripheral neuropathy and modulation by N-acetyl-L-cysteine in rats.
Naik AK
Eur J Pain. 2006 Oct;10(7):573-9.

29. Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenan-induced acute inflammation in rats.
Dudhgaonkar SP
Life Sci. 2006 Feb 2;78(10):1044-8.

30. Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in Brewer's yeast induced pyrexia in mice: an isobolographic study.
Bhat AS
Eur J Pharmacol. 2005 Mar 28;511(2-3):137-42.

31. Electrophysiological and pharmacological characterization of K+-currents in muscle fibres isolated from the ventral sucker of Fasciola hepatica.
Kumar D
Parasitology. 2004 Dec;129(Pt 6):779-93.

32. Interaction of inducible nitric oxide synthase and cyclooxygenase-2 inhibitors in formalin-induced nociception in mice.
Dudhgaonkar SP
Eur J Pharmacol. 2004 May 25;492(2-3):117-22.

33. Observations on the musculature and isolated muscle fibres of the liver fluke, Fasciola hepatica.
Kumar D
Parasitology. 2003 Nov;127(Pt 5):457-73.

34. Antinociceptive and antipyretic activities of Pongamia pinnata leaves.
Srinivasan K
Phytother Res. 2003 Mar;17(3):259-64.

35. Effect of centrally administered nitric oxide modulators in Brewer's yeast-induced nociception in rats.
Sarma J
Indian J Exp Biol. 2000 Nov;38(11):1123-8.

36. Central noradrenergic & dopaminergic modulation of brewer's yeast-induced inflammation & nociception in rats.
Hore SK
Indian J Med Res. 1997 Feb;105:93-7.
9055502
37. Central modulation of Brewer's yeast-induced peripheral inflammation by neuropeptides bradykinin and substance P.
Hore SK
Indian J Physiol Pharmacol. 1996 Oct;40(4):367-71.
9055109

Publications

  1. ncbi request reprint Antinociceptive and antipyretic activities of Pongamia pinnata leaves
    K Srinivasan
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izat nagar U P, 243 122, India
    Phytother Res 17:259-64. 2003
  2. doi request reprint Increased hyperalgesia by 5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats
    Vinod D Ramteke
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute Izatnagar, Bareilly, U P, 243 122, India
    Pharmacol Biochem Behav 91:417-22. 2009
  3. doi request reprint Effects of amino acid neurotransmitters on spontaneous muscular activity of the rumen amphistome, Gastrothylax crumenifer
    P K Verma
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly 243 122, UP, India
    J Helminthol 83:385-9. 2009
  4. doi request reprint Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica
    Thakur Uttam Singh
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243122 U P, India
    Exp Parasitol 123:302-8. 2009
  5. doi request reprint Neuroprotective effect of 5,7,3',4',5'-pentahydroxy dihydroflavanol-3-O-(2''-O-galloyl)-beta-D-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat
    Rathinam Arunadevi
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, IZATNAGAR 243 122 U P, India
    Eur J Pharmacol 626:205-12. 2010
  6. doi request reprint Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat
    Rathinam Arunadevi
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly, U P 243 122, India
    Nitric Oxide 22:1-10. 2010
  7. ncbi request reprint Autologous bone marrow-derived cells for healing excisional dermal wounds of rabbits
    B M Borena
    Division of Surgery, Indian Veterinary Research Institute, Izatnagar 243122 UP, India
    Vet Rec 165:563-8. 2009
  8. doi request reprint Evaluation of autologous bone marrow-derived nucleated cells for healing of full-thickness skin wounds in rabbits
    B M Borena
    Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India
    Int Wound J 7:249-60. 2010
  9. doi request reprint Pro-healing potential of hemin: an inducer of heme oxygenase-1
    Azad A Ahanger
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar UP, PIN 243 122, India
    Eur J Pharmacol 645:165-70. 2010
  10. pmc Paralytic effect of alcoholic extract of Allium sativum and Piper longum on liver amphistome, Gigantocotyle explanatum
    T U Singh
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243 122, UP, India
    Indian J Pharmacol 40:64-8. 2008

Collaborators

  • - Amarpal
  • Saurabh Kumar
  • P Kinjavdekar
  • I Fairweather
  • R Prasad
  • S Chandra
  • S Muruganandan
  • R Singh
  • Thakur Uttam Singh
  • K Srinivasan
  • Surendra K Tandan
  • Shailesh P Dudhgaonkar
  • Abdul Shakoor Bhat
  • Vellanki Ravi Prakash
  • Ajit K Naik
  • Rathinam Arunadevi
  • B M Borena
  • Vinod D Ramteke
  • Surendra Kumar Tandan
  • S K Tandan
  • Marie Dennis Marcus Leo
  • Vamsi Krishna
  • Tariq Ahmad Wani
  • T A Wani
  • Azad A Ahanger
  • A M Pawde
  • H P Aithal
  • Manoj K Shukla
  • P K Verma
  • S P Dudhgaonkar
  • V Ravi Prakash
  • V Raviprakash
  • Sachin H Jadhav
  • H H Chandrashekara
  • A Gopal
  • Kaustuk K Sardar
  • Pawan Kumar Verma
  • K K Sardar
  • Shahid Prawez
  • Jitendra K Malik
  • Subramani Jaganathan
  • Anil K Sharma
  • Suman Lata
  • Brijesh K Bhadoria
  • Kandaswamy Kathirvel
  • Palanisamy Sankar
  • R Aruna Devi
  • R Arunadevi
  • Yeshavanth K B Siddegowda
  • Kochiganti V H Sastry
  • Santosh K Mishra
  • M Kataria
  • Meena Kataria
  • Dnyaneshwar U Bawankule
  • Aruna R Devi
  • Ajit Naik

Detail Information

Publications25

  1. ncbi request reprint Antinociceptive and antipyretic activities of Pongamia pinnata leaves
    K Srinivasan
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izat nagar U P, 243 122, India
    Phytother Res 17:259-64. 2003
    ..These results demonstrated that PLE possesses marked antinociceptive as well as antipyretic activities and thus scientifically validated its use in the treatment of pain and pyretic disorders...
  2. doi request reprint Increased hyperalgesia by 5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats
    Vinod D Ramteke
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute Izatnagar, Bareilly, U P, 243 122, India
    Pharmacol Biochem Behav 91:417-22. 2009
    ..p. or i.c.v. route of administration, has no effect on pain symptoms in this model. NPPB hyperalgesic effect is independent of CaCCs inhibition and may be due to blockade of Ca2+-activated K+ channel...
  3. doi request reprint Effects of amino acid neurotransmitters on spontaneous muscular activity of the rumen amphistome, Gastrothylax crumenifer
    P K Verma
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly 243 122, UP, India
    J Helminthol 83:385-9. 2009
    ..These observations suggested that L-glutamate has an excitatory, whereas GABA and glycine have an inhibitory, effect on the spontaneous muscular activity of G. crumenifer...
  4. doi request reprint Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica
    Thakur Uttam Singh
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243122 U P, India
    Exp Parasitol 123:302-8. 2009
    ..In conclusion, the observations demonstrated irreversible paralytic effect of essential oils of A. sativum and P. longum on F. giganticain vitro which might possibly help to developing herbal-based anthelmintic...
  5. doi request reprint Neuroprotective effect of 5,7,3',4',5'-pentahydroxy dihydroflavanol-3-O-(2''-O-galloyl)-beta-D-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat
    Rathinam Arunadevi
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, IZATNAGAR 243 122 U P, India
    Eur J Pharmacol 626:205-12. 2010
    ..AP1 can be used as a neuroprotective agent in stroke as it reduced apoptosis and found to be a good antioxidant and anti-inflammatory compound...
  6. doi request reprint Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat
    Rathinam Arunadevi
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly, U P 243 122, India
    Nitric Oxide 22:1-10. 2010
    ..SMT protected Neuro 2a cells against sodium azide-induced damage. It is concluded that, SMT may possibly targeting both constitutive as well as inducible NOS at varying time interval to elicit neuroprotection in TFCI rats...
  7. ncbi request reprint Autologous bone marrow-derived cells for healing excisional dermal wounds of rabbits
    B M Borena
    Division of Surgery, Indian Veterinary Research Institute, Izatnagar 243122 UP, India
    Vet Rec 165:563-8. 2009
    ....
  8. doi request reprint Evaluation of autologous bone marrow-derived nucleated cells for healing of full-thickness skin wounds in rabbits
    B M Borena
    Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India
    Int Wound J 7:249-60. 2010
    ..The injection of autologous bone marrow-derived nucleated cells can be used to promote healing of large full-thickness skin wounds in rabbits...
  9. doi request reprint Pro-healing potential of hemin: an inducer of heme oxygenase-1
    Azad A Ahanger
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar UP, PIN 243 122, India
    Eur J Pharmacol 645:165-70. 2010
    ..mRNA expression of cytokines endorsed fast healing as was indicated by inhibition of pro-inflammatory cytokines such as ICAM-1 and TNF-alpha and up-regulation of anti-inflammatory cytokine IL-10...
  10. pmc Paralytic effect of alcoholic extract of Allium sativum and Piper longum on liver amphistome, Gigantocotyle explanatum
    T U Singh
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243 122, UP, India
    Indian J Pharmacol 40:64-8. 2008
    ..To investigate the effects of alcoholic extract of Allium sativum and Piper longum on the muscular activity of a parasitic amphistome, Gigantocotyle explanatum...
  11. ncbi request reprint Wound healing activity of ethanolic extract of Shorea robusta Gaertn. f. resin
    T A Wani
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243 122, India
    Indian J Exp Biol 50:277-81. 2012
    ..The results demonstrate wound healing activity of ethanolic extract of S. robusta resin...
  12. doi request reprint Role of nitric oxide and carbon monoxide in N(omega)-Nitro-L-arginine methyl ester-resistant acetylcholine-induced relaxation in chicken carotid artery
    Marie Dennis Marcus Leo
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India
    Eur J Pharmacol 596:111-7. 2008
    ..In conclusion, it is suggested that the acetylcholine-induced L-NAME-resistant relaxation is primarily, mediated by NO with a small but significant contribution from endothelium-derived carbon monoxide in the chicken carotid artery...
  13. doi request reprint The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study
    Abdul Shakoor Bhat
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly, UP 243 122, India
    Anesth Analg 106:978-84, table of contents. 2008
    ....
  14. ncbi request reprint Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats
    S P Dudhgaonkar
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Dist Bareilly, PIN 243 122, UP India
    Inflammopharmacology 15:188-95. 2007
    ....
  15. ncbi request reprint Observations on the musculature and isolated muscle fibres of the liver fluke, Fasciola hepatica
    D Kumar
    Parasite Proteomics and Therapeutics Research Group, School of Biology, and Biochemistry, The Queen s University of Belfast, Belfast BT9 7BL, Northern Ireland
    Parasitology 127:457-73. 2003
    ..The muscle fibres contain actin and myosin, but lack a nucleus, the connection with the cell body having been broken during the isolation procedure...
  16. ncbi request reprint Interaction of inducible nitric oxide synthase and cyclooxygenase-2 inhibitors in formalin-induced nociception in mice
    Shailesh P Dudhgaonkar
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, DIST, Bareilly Pin 243 122, U P India
    Eur J Pharmacol 492:117-22. 2004
    ..Furthermore, the present results suggest that combination therapy with rofecoxib and aminoguanidine hydrochloride may provide an alternative for the clinical control of pain...
  17. ncbi request reprint Electrophysiological and pharmacological characterization of K+-currents in muscle fibres isolated from the ventral sucker of Fasciola hepatica
    D Kumar
    Parasite Proteomics and Therapeutics Research Group, School of Biology and Biochemistry, The Queen s University of Belfast, Belfast BT9 7BL, Northern Ireland
    Parasitology 129:779-93. 2004
    ..We conclude that voltage-and Ca2+-sensitive K+-channels are expressed in this tissue, but that their pharmacology differs considerably from equivalent channels in other phyla...
  18. ncbi request reprint Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in Brewer's yeast induced pyrexia in mice: an isobolographic study
    Abdul Shakoor Bhat
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly, U P 243 122, India
    Eur J Pharmacol 511:137-42. 2005
    ..Results suggest involvement of a mediator that is subservient to both inducible nitric oxide synthase and cyclooxygenase-2 enzyme activities. For further investigation, peroxynitrite ion may be considered to be the putative mediator...
  19. ncbi request reprint Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenan-induced acute inflammation in rats
    Shailesh P Dudhgaonkar
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, U P 243 122 India
    Life Sci 78:1044-8. 2006
    ..These results suggest that co-administration of meloxicam and aminoguanidine hydrochloride may be an alternative in clinical control of inflammation...
  20. ncbi request reprint Role of oxidative stress in pathophysiology of peripheral neuropathy and modulation by N-acetyl-L-cysteine in rats
    Ajit K Naik
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243 122 UP, India
    Eur J Pain 10:573-9. 2006
    ..Effect of N-acetyl-L-cysteine (NAC) administered intraperitoneally, was also investigated on CCI-induced neuropathic pain in rats...
  21. ncbi request reprint Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats
    Ajit K Naik
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar
    Eur J Pharmacol 530:59-69. 2006
    ..In conclusion, initial attempt to manipulate L-arginine: NO pathway is indicative of therapeutic potential of these interventions in the management of neuropathic pain...
  22. ncbi request reprint Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats
    Shailesh P Dudhgaonkar
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Bareilly, Izatnagar 243 122, UP, India
    Eur J Pain 11:528-34. 2007
    ....
  23. ncbi request reprint Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in adjuvant-induced arthritis in female albino rats: an isobolographic study
    Abdul Shakoor Bhat
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly, U P 243122, India
    Eur J Pharmacol 556:190-9. 2007
    ..Simultaneous inhibition of inducible nitric oxide synthase and cyclooxygenase appears to offer an alternative approach for ameliorating the progression of arthritis...
  24. ncbi request reprint Synergistic interaction between meloxicam and aminoguanidine in formalin-induced nociception in mice
    Shailesh P Dudhgaonkar
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, 243122 Uttar Pradesh, India
    Eur J Pain 12:321-8. 2008
    ....
  25. pmc Analgesic activity of the ethanolic extract of Shorea robusta resin in experimental animals
    Tariq Ahmad Wani
    Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, UP, India
    Indian J Pharmacol 44:493-9. 2012
    ..In the present study, ethanolic extract of S. robusta resin (SRE) was evaluated for its analgesic activity by making use of different central and peripheral pain models...