James G Kublin

Summary

Publications

  1. ncbi request reprint Effect of Plasmodium falciparum malaria on concentration of HIV-1-RNA in the blood of adults in rural Malawi: a prospective cohort study
    James G Kublin
    Department of Community Health, University of Malawi College of Medicine, Blantyre, Malawi
    Lancet 365:233-40. 2005
  2. ncbi request reprint A prospective study of bloodstream infections as cause of fever in Malawi: clinical predictors and implications for management
    Remco P H Peters
    Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi
    Trop Med Int Health 9:928-34. 2004
  3. ncbi request reprint Prevalence and indicators of HIV and AIDS among adults admitted to medical and surgical wards in Blantyre, Malawi
    David K Lewis
    Department of Medicine, University of Malawi College of Medicine, Private Bag 360, Chichiri, Blantyre 3, Malawi
    Trans R Soc Trop Med Hyg 97:91-6. 2003
  4. ncbi request reprint Challenges in the prevention, diagnosis, and treatment of malaria in human immunodeficiency virus infected adults in sub-Saharan Africa
    Paula E Brentlinger
    Department of Health Services, School of Public Health and Community Medicine, Box 357660, University of Washington, Seattle, WA 98195, USA
    Arch Intern Med 167:1827-36. 2007
  5. ncbi request reprint Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa
    Laith J Abu-Raddad
    Statistical Center for HIV Aids Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Science 314:1603-6. 2006
  6. ncbi request reprint Effects of HIV-1 serostatus, HIV-1 RNA concentration, and CD4 cell count on the incidence of malaria infection in a cohort of adults in rural Malawi
    Padmaja Patnaik
    Department of Epidemiology, University of North Carolina at Chapel Hill, 27599, USA
    J Infect Dis 192:984-91. 2005
  7. ncbi request reprint HIV infection and malaria--understanding the interactions
    James G Kublin
    J Infect Dis 193:1-3. 2006
  8. pmc Association between the pharmacokinetics and in vivo therapeutic efficacy of sulfadoxine-pyrimethamine in Malawian children
    Fraction K Dzinjalamala
    University of Cape Town, Division of Clinical Pharmacology, K50 Old Main Building, Groote Schuur Hospital, Cape Town 7925, South Africa
    Antimicrob Agents Chemother 49:3601-6. 2005
  9. ncbi request reprint Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria
    Fraction K Dzinjalamala
    Division of Pharmacology, University of Cape Town, Cape Town, South Africa
    Am J Trop Med Hyg 72:267-72. 2005
  10. ncbi request reprint Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites
    Sarah J Bates
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    J Infect Dis 190:1783-92. 2004

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Effect of Plasmodium falciparum malaria on concentration of HIV-1-RNA in the blood of adults in rural Malawi: a prospective cohort study
    James G Kublin
    Department of Community Health, University of Malawi College of Medicine, Blantyre, Malawi
    Lancet 365:233-40. 2005
    ..To assess the effect of Plasmodium falciparum malaria on concentrations of HIV in blood, we did a prospective cohort study in Malawi...
  2. ncbi request reprint A prospective study of bloodstream infections as cause of fever in Malawi: clinical predictors and implications for management
    Remco P H Peters
    Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi
    Trop Med Int Health 9:928-34. 2004
    ..To determine the contribution of a blood culture service to the diagnosis of fever in a resource-poor setting and to identify clinical predictors of specific bloodstream infections (BSI)...
  3. ncbi request reprint Prevalence and indicators of HIV and AIDS among adults admitted to medical and surgical wards in Blantyre, Malawi
    David K Lewis
    Department of Medicine, University of Malawi College of Medicine, Private Bag 360, Chichiri, Blantyre 3, Malawi
    Trans R Soc Trop Med Hyg 97:91-6. 2003
    ..4). Severe bacterial infections, TB and AIDS caused 68% of deaths. HIV dominates adult medicine, is a major part of adult surgery, is the main cause of death in hospital and affects the economically active age group of the population...
  4. ncbi request reprint Challenges in the prevention, diagnosis, and treatment of malaria in human immunodeficiency virus infected adults in sub-Saharan Africa
    Paula E Brentlinger
    Department of Health Services, School of Public Health and Community Medicine, Box 357660, University of Washington, Seattle, WA 98195, USA
    Arch Intern Med 167:1827-36. 2007
    ..The likelihood of HIV-malaria coinfection may affect clinical management of patients. The extent to which standard clinical guidelines address HIV-malaria coinfection is unclear...
  5. ncbi request reprint Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa
    Laith J Abu-Raddad
    Statistical Center for HIV Aids Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Science 314:1603-6. 2006
    ..Hence, transient and repeated increases in HIV viral load resulting from recurrent co-infection with malaria may be an important factor in promoting the spread of HIV in sub-Saharan Africa...
  6. ncbi request reprint Effects of HIV-1 serostatus, HIV-1 RNA concentration, and CD4 cell count on the incidence of malaria infection in a cohort of adults in rural Malawi
    Padmaja Patnaik
    Department of Epidemiology, University of North Carolina at Chapel Hill, 27599, USA
    J Infect Dis 192:984-91. 2005
    ....
  7. ncbi request reprint HIV infection and malaria--understanding the interactions
    James G Kublin
    J Infect Dis 193:1-3. 2006
  8. pmc Association between the pharmacokinetics and in vivo therapeutic efficacy of sulfadoxine-pyrimethamine in Malawian children
    Fraction K Dzinjalamala
    University of Cape Town, Division of Clinical Pharmacology, K50 Old Main Building, Groote Schuur Hospital, Cape Town 7925, South Africa
    Antimicrob Agents Chemother 49:3601-6. 2005
    ..falciparum should be interpreted with caution and needs further validation...
  9. ncbi request reprint Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria
    Fraction K Dzinjalamala
    Division of Pharmacology, University of Cape Town, Cape Town, South Africa
    Am J Trop Med Hyg 72:267-72. 2005
    ....
  10. ncbi request reprint Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites
    Sarah J Bates
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    J Infect Dis 190:1783-92. 2004
    ..Overall, these results suggest that dhfr alleles that confer high levels of resistance to antifolates are rare, even in eastern and southern Africa, where pyrimethamine has been intensively used...
  11. pmc Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study
    Christopher V Plowe
    Malaria Section, Center for Vaccine Development, University of Maryland School of Medicine, 685 West Baltimore Street, HSF1 480, Baltimore, MD 21044, USA
    BMJ 328:545. 2004
    ..To measure the efficacy of sulfadoxine-pyrimethamine treatment of falciparum malaria in Malawi from 1998 to 2002, after a change from chloroquine to sulfadoxine-pyrimethamine as first line treatment in that country in 1993...
  12. ncbi request reprint Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi
    James G Kublin
    Malaria Section, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Infect Dis 187:1870-5. 2003
    ..The reintroduction of chloroquine, ideally in combination with another antimalarial drug, should be considered in areas where chloroquine resistance has declined and safe and affordable alternatives remain unavailable...
  13. ncbi request reprint Immediate-type hypersensitivity and other clinical reactions in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites
    Robert Edelman
    Department of Medicine, University of Maryland School of Medicine, Room 480, 685 West Baltimore Street, Baltimore, MD 21201 USA
    Vaccine 21:269-80. 2002
    ..Five of five non-immunized persons were also ITH-ST negative. ITH-STs may help identify individuals sensitized to malaria peptides and at potential risk of developing systemic allergic reactions after re-vaccination...
  14. ncbi request reprint Delayed-type hypersensitivity in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites
    James G Kublin
    Department of Medicine and Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, USA
    Vaccine 20:1853-61. 2002
    ..We conclude that the presence of T cell functional activity reflected by a positive DTH skin test response to the MAP antigen serves as another marker for vaccine immunogenicity...
  15. ncbi request reprint Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria
    James G Kublin
    Malaria Section, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, USA
    J Infect Dis 185:380-8. 2002
    ..If this model is validated in other populations, it will finally be possible to use molecular markers for surveillance of antifolate-resistant P. falciparum malaria in Africa...