FDG-PET staging and importance of lymph node SUV in head and neck cancerGregory J Kubicek
Thomas Jefferson University Hospital, Philadelphia, PA, USA
Head Neck Oncol 2:19. 2010
..The NCCN guidelines do not recommend FDG-PET as a part of standard workup. The purpose of this report is to examine the role of FDG-PET imaging in altering management and providing prognostic information for HNC...
Chemotherapy in head and neck cancer: clinical predictors of tolerance and outcomesGregory J Kubicek
Department of Radiation Oncology, University of Pittsburgh Medical Center, PA, USA
Am J Clin Oncol 34:380-4. 2011
..However, little data are available regarding the best chemotherapy agent and dosing, or factors associated with chemotherapy compliance...
- Phase I trial using the proteasome inhibitor bortezomib and concurrent chemoradiotherapy for head-and-neck malignancies
Gregory J Kubicek
Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 83:1192-7. 2012
..This Phase I dose-escalation study examined the potential of bortezomib in combination with cisplatin chemotherapy and concurrent radiation in the treatment of locally advanced and recurrent HNC...
- Target delineation in stereotactic body radiation therapy for recurrent head and neck cancer: a retrospective analysis of the impact of margins and automated PET-CT segmentation
Kyle Wang
Department of Radiation Oncology, University of Pittsburg Cancer Institute, Pittsburg, PA, USA
Radiother Oncol 106:90-5. 2013
..We assessed the impact of retrospectively adding margins/automated PET volumes to the gross tumor volume (GTV) in patients with post-SBRT recurrences...
- Combined transperineal implant and external beam radiation for the treatment of prostate cancer: a large patient cohort in the community setting
Gregory J Kubicek
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA
Brachytherapy 10:449-53. 2011
..Our purpose was to report the results of combined modality therapy from a single institution in the community setting...
- Value of fluoro-2-deoxy-D-glucose-positron emission tomography for detecting metastatic lesions in head and neck cancer
Shannon E Fogh
Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
Am J Clin Oncol 35:311-5. 2012
..The purpose of this report is to examine the accuracy of staging PET scans for detecting distant metastatic disease in patients with HNC...
- A retrospective, deformable registration analysis of the impact of PET-CT planning on patterns of failure in stereotactic body radiation therapy for recurrent head and neck cancer
Kyle Wang
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
Head Neck Oncol 4:12. 2012
..We analyzed the patterns of failure following SBRT for rSCCHN and assessed the impact of PET-CT treatment planning on these patterns of failure...
- Importance of treatment institution in head and neck cancer radiotherapy
Gregory J Kubicek
Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19147, USA
Otolaryngol Head Neck Surg 141:172-6. 2009
..Our goal is to determine if these potential AC advantages correspond to a difference in treatment outcome...
- New advances in high-technology radiotherapy for head and neck cancer
Gregory J Kubicek
Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
Hematol Oncol Clin North Am 22:1165-80, viii. 2008
..Some of these advances are discussed in this article...
- Phase I trial using proteasome inhibitor bortezomib and concurrent temozolomide and radiotherapy for central nervous system malignancies
Gregory J Kubicek
Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 74:433-9. 2009
..To evaluate the toxicity and response rate of bortezomib with concurrent radiotherapy and temozolomide in the treatment of patients with central nervous system malignancies...
- Do elderly patients experience increased perioperative or postoperative morbidity or mortality when given neoadjuvant chemoradiation before esophagectomy?
Shannon E Fogh
Department of Radiation Oncology, University of California, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 80:1372-6. 2011
....
- The role of cetuximab in the management of head and neck cancers
Peyman Kabolizadeh
University of Pittsburgh Cancer Institute, Department of Radiation Oncology, Pittsburgh, PA 15232, USA
Expert Opin Biol Ther 12:517-28. 2012
..While cetuximab is a valuable tool in the treatment of SCCHN, more studies are needed to maximize the efficacy of this mAb in clinical settings and to identify the subpopulation of patients that truly benefit from its use...
- PSA decrease during combined-modality radiotherapy predicts for treatment outcome
Gregory J Kubicek
Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 78:759-62. 2010
..Although reports have focused on the importance of pretreatment PSA levels, doubling time, and posttreatment nadirs, there is little information on the value of PSA during the course of radiotherapy...
