Genome diversity of the TetR family of transcriptional regulators in a metal-reducing bacterial family Geobacteraceae and other microbial speciesJulia Krushkal
Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, USA
OMICS 15:495-506. 2011
..In order to understand the role of the TetR regulatory family in Geobacteraceae, we have inferred phylogenetic relationships among the Geobacteraceae TetR proteins and their homologs in other microbial species...
- Genome-wide survey for PilR recognition sites of the metal-reducing prokaryote Geobacter sulfurreducens
Julia Krushkal
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Gene 469:31-44. 2010
..sulfurreducens PilR in regulation of production and assembly of pili and flagella...
Computational prediction of RpoS and RpoD regulatory sites in Geobacter sulfurreducens using sequence and gene expression informationBin Yan
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA
Gene 384:73-95. 2006
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- Genome-wide similarity search for transcription factors and their binding sites in a metal-reducing prokaryote Geobacter sulfurreducens
Bin Yan
Department of Preventive Medicine, University of Tennessee Health Science Center, 66 N Pauline St, Ste 633, Memphis, TN 38163, USA
Biosystems 90:421-41. 2007
..The closest homolog of E. coli RpoE in G. sulfurreducens may be more similar to FecI than to RpoE. These findings represent the first step in the understanding of the regulatory relationships in G. sulfurreducens on the genome scale...
- Genome-wide expression profiling in Geobacter sulfurreducens: identification of Fur and RpoS transcription regulatory sites in a relGsu mutant
Julia Krushkal
Department of Preventive Medicine, University of Tennessee Health Science Center, 66 N Pauline, Memphis, TN 38163, USA
Funct Integr Genomics 7:229-55. 2007
..These findings suggest that Fur- and RpoS-dependent gene expression in G. sulfurreducens is affected by Rel(Gsu)-mediated signaling...
Racial differences in gene-specific DNA methylation levels are present at birthRonald M Adkins
University of Tennessee Health Science Center, Memphis, TN 48103, USA
Birth Defects Res A Clin Mol Teratol 91:728-36. 2011
..The origin of these differences is inadequately understood, and this is a question of specific relevance to childhood and adult cancer...
- GSEL version 2, an online genome-wide query system of operon organization and regulatory sequence elements of Geobacter sulfurreducens
Yanhua Qu
Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
OMICS 13:439-49. 2009
..sulfurreducens, aiding in investigation of mechanisms that regulate its ability to generate electric power, bioremediate environmental waste, and adapt to environmental changes...
- Association of maternally inherited GNAS alleles with African-American male birth weight
Ronald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA
Int J Pediatr Obes 5:177-84. 2010
..We performed a survey of single nucleotide polymorphisms (SNPs) in 14 candidate genes to identify associations with birth weight variation...
- Newborn umbilical cord blood DNA methylation and gene expression levels exhibit limited association with birth weight
Ronald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA
Chem Biodivers 9:888-99. 2012
..However, our discovery of biologically plausible associations in a peripheral tissue suggests that further studies of tissues key to fetal growth regulation are warranted...
- Diversity of promoter elements in a Geobacter sulfurreducens mutant adapted to disruption in electron transfer
Julia Krushkal
Department of Preventive Medicine, University of Tennessee Health Science Center, 66 N Pauline Ste 633, Memphis, TN 38163, USA
Funct Integr Genomics 9:15-25. 2009
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- Phylogenetic classification of diverse LysR-type transcriptional regulators of a model prokaryote Geobacter sulfurreducens
Julia Krushkal
Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Mol Evol 74:187-205. 2012
..sulfurreducens LTTRs. This is the first study to date providing a detailed classification of LTTRs in the deltaproteobacterial family Geobacteraceae...
- Alpha-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults
Robert M Kelsey
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38104, USA
Psychophysiology 49:401-12. 2012
..Thus, specific associations emerged between genetic variations in α-Ars and cardiovascular reactivity in young Blacks...
- Site -2548 of the leptin gene is associated with gender-specific trends in newborn size and cord leptin levels
Ronald M Adkins
Children s Foundation Research Center and Center of Genomics and Bioinformatics, University of Tennessee Health Science Center, Memphis, TN 38122, USA
Int J Pediatr Obes 2:130-7. 2007
..We examined the relationships among leptin gene polymorphisms, size for gestational age, umbilical cord leptin, and gender...
- Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes
Ronald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee 38103, USA
Pediatr Res 68:429-34. 2010
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- Computational prediction of conserved operons and phylogenetic footprinting of transcription regulatory elements in the metal-reducing bacterial family Geobacteraceae
Bin Yan
Department of Preventive Medicine, Center of Genomics and Bioinformatics, University of Tennesee Health Science Center, 66 N. Pauline St, Ste. 633, Memphis, TN 38163, USA
J Theor Biol 230:133-44. 2004
..These predictions will aid in further elucidation of regulatory networks of gene interactions in Geobacteraceae...
- Parental ages and levels of DNA methylation in the newborn are correlated
Ronald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA
BMC Med Genet 12:47. 2011
..Only a proportion of these increased risks among the children of older parents can be attributed to nondisjunction and chromosomal rearrangements...
- Beta-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults
Robert M Kelsey
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
Psychophysiology 47:863-73. 2010
..Thus, specific patterns of associations emerged between genetic variations in beta-ARs and cardiovascular reactivity in young Blacks...
- Association between paternally inherited haplotypes upstream of the insulin gene and umbilical cord IGF-II levels
Ronald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee 38103, USA
Pediatr Res 62:451-5. 2007
..Analyses of haplotypes inferred from these two SNPs demonstrate a significant relationship between paternally transmitted haplotypes and newborn IGF-II levels, but no association with maternally transmitted haplotypes...
- Computational analysis of the evolution of the structure and function of 1-deoxy-D-xylulose-5-phosphate synthase, a key regulator of the mevalonate-independent pathway in plants
Julia Krushkal
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Gene 313:127-38. 2003
..To our knowledge this is the first suggestion that DXS is located specifically in the chloroplast thylakoid...
