Girish J Kotwal

Summary

Publications

  1. pmc Investigation of interaction of vaccinia virus complement control protein and curcumin with complement components c3 and c3b using quartz crystal microbalance with dissipation monitoring technology
    Amod P Kulkarni
    Division of Neuroscience, Department of Human Biology, University of Cape Town, Cape Town South Africa
    Open Biochem J 4:9-21. 2010
  2. ncbi request reprint Avian Influenza in Humans--First Annual Conference. Latest advances on prevention, therapies and protective measures. 29-30 June 2006, Paris, France
    Girish J Kotwal
    Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory Cape Town 7925, South Africa
    IDrugs 9:625-6. 2006
  3. doi request reprint Genetic diversity-independent neutralization of pandemic viruses (e.g. HIV), potentially pandemic (e.g. H5N1 strain of influenza) and carcinogenic (e.g. HBV and HCV) viruses and possible agents of bioterrorism (variola) by enveloped virus neutralizing com
    Girish J Kotwal
    Department of Medicine, University of Massachusettes, Worcester, MA 01605, USA
    Vaccine 26:3055-8. 2008
  4. doi request reprint Central nervous system distribution of the poxviral proteins after intranasal administration of proteins and titering of vaccinia virus in the brain after intracranial administration
    Amod P Kulkarni
    Division of Anatomical Pathology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Methods Mol Biol 890:305-26. 2012
  5. doi request reprint Application of quartz crystal microbalance with dissipation monitoring technology for studying interactions of poxviral proteins with their ligands
    Amod P Kulkarni
    Division of Anatomical Pathology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Methods Mol Biol 890:289-303. 2012
  6. doi request reprint Characterization of poxvirus-encoded proteins that regulate innate immune signaling pathways
    Florentina Rus
    Division of Infectious Disease, Department of Medicine, University of Massachusetts School of Medicine, Worcester, MA, USA
    Methods Mol Biol 890:273-88. 2012
  7. doi request reprint Vaccinia virus complement control protein (VCP) improves kidney structure and function following ischemia/reperfusion injury in rats
    Yohannes T Ghebremariam
    Division of Medical Virology, IIDMM, University of Cape Town, FHS, Cape Town, South Africa Division of General Surgery, Department of Surgery, University of Cape Town, GSH, FHS, Cape Town, South Africa
    J Surg Res 159:747-54. 2010
  8. doi request reprint Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test
    Amod P Kulkarni
    Division of Medical Virology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, Anzio Road, Observatory 07925, Cape Town, South Africa
    Biogerontology 9:405-20. 2008
  9. ncbi request reprint Purification of 3 monomeric monocot mannose-binding lectins and their evaluation for antipoxviral activity: potential applications in multiple viral diseases caused by enveloped viruses
    Amandeep Kaur
    Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, 143 005 Punjab, India
    Biochem Cell Biol 85:88-95. 2007
  10. ncbi request reprint Antiviral activity of purified human breast milk mucin
    Habtom H Habte
    Department of Surgery, University of Cape Town, Cape Town, South Africa
    Neonatology 92:96-104. 2007

Collaborators

  • Amod P Kulkarni
  • Lauriston A Kellaway
  • Florentina Rus
  • Dhirendra Govender
  • Yohannes T Ghebremariam
  • Amandeep Kaur
  • Habtom H Habte
  • Melissa Abrahams
  • Michela Ballardin
  • Ngoc Pham
  • William L Marshall
  • Kayla Morlock
  • Neal Silverman
  • Krishna Murthy
  • Marilyn Tyler
  • Zoe Lotz
  • Gert Engelbrecht
  • Philippa J Randall
  • Del Kahn
  • Nirvana S Pillay
  • ZoĆ« E Lotz
  • Jatinder Singh
  • Sukhdev Singh Kamboj
  • Delawir Kahn
  • Rajinder Singh
  • Marilyn G Tyler
  • Jerry Rodriques
  • A K Saxena
  • Anwar S Mall
  • Roberto Barale
  • Roberto Scarpato

Detail Information

Publications11

  1. pmc Investigation of interaction of vaccinia virus complement control protein and curcumin with complement components c3 and c3b using quartz crystal microbalance with dissipation monitoring technology
    Amod P Kulkarni
    Division of Neuroscience, Department of Human Biology, University of Cape Town, Cape Town South Africa
    Open Biochem J 4:9-21. 2010
    ..This technology was applied to characterize the interactions of VCP, Cur and appropriate controls with the key complement components. Cur as well as VCP showed binding to both C3 and to C3b, Cur however bound to C3b to a lesser extent...
  2. ncbi request reprint Avian Influenza in Humans--First Annual Conference. Latest advances on prevention, therapies and protective measures. 29-30 June 2006, Paris, France
    Girish J Kotwal
    Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory Cape Town 7925, South Africa
    IDrugs 9:625-6. 2006
  3. doi request reprint Genetic diversity-independent neutralization of pandemic viruses (e.g. HIV), potentially pandemic (e.g. H5N1 strain of influenza) and carcinogenic (e.g. HBV and HCV) viruses and possible agents of bioterrorism (variola) by enveloped virus neutralizing com
    Girish J Kotwal
    Department of Medicine, University of Massachusettes, Worcester, MA 01605, USA
    Vaccine 26:3055-8. 2008
    ..How EVNCs will be used in developing a vaccine achieving sterilizing immunity or prophylaxis needs to be researched...
  4. doi request reprint Central nervous system distribution of the poxviral proteins after intranasal administration of proteins and titering of vaccinia virus in the brain after intracranial administration
    Amod P Kulkarni
    Division of Anatomical Pathology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Methods Mol Biol 890:305-26. 2012
    ..These protocols can be extended to examine the distribution of viral antigens in the brain. A protocol is also included to quantitate vaccinia virus in different segments of the brain after intracranial administration of the virus...
  5. doi request reprint Application of quartz crystal microbalance with dissipation monitoring technology for studying interactions of poxviral proteins with their ligands
    Amod P Kulkarni
    Division of Anatomical Pathology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Methods Mol Biol 890:289-303. 2012
    ..The protocol can also be used as a prototype for studying both proteins and small-sized compounds (for use as anti-poxvirals) for their ability to interact with and/or inhibit the activity of their ligands...
  6. doi request reprint Characterization of poxvirus-encoded proteins that regulate innate immune signaling pathways
    Florentina Rus
    Division of Infectious Disease, Department of Medicine, University of Massachusetts School of Medicine, Worcester, MA, USA
    Methods Mol Biol 890:273-88. 2012
    ..Novel poxviral innate immune inhibitors are being identified via several approaches and these techniques promise to identify further complexities in the way that poxviruses interact with the host innate immune system...
  7. doi request reprint Vaccinia virus complement control protein (VCP) improves kidney structure and function following ischemia/reperfusion injury in rats
    Yohannes T Ghebremariam
    Division of Medical Virology, IIDMM, University of Cape Town, FHS, Cape Town, South Africa Division of General Surgery, Department of Surgery, University of Cape Town, GSH, FHS, Cape Town, South Africa
    J Surg Res 159:747-54. 2010
    ..The immunohistochemical study showed significant C3 deposition in the renal tubules of the PBS controls compared with the rVCP or VCP/hrVCP groups, suggesting that rVCP, VCP/hrVCP reduced I/R injury by inhibiting the biosynthesis of C3...
  8. doi request reprint Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test
    Amod P Kulkarni
    Division of Medical Virology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine IIDMM, University of Cape Town, Anzio Road, Observatory 07925, Cape Town, South Africa
    Biogerontology 9:405-20. 2008
    ..These results suggest that administration of VCP at an early age in transgenic mice may be effective in regulating the progression to the familial form of Alzheimer's disease at a later age...
  9. ncbi request reprint Purification of 3 monomeric monocot mannose-binding lectins and their evaluation for antipoxviral activity: potential applications in multiple viral diseases caused by enveloped viruses
    Amandeep Kaur
    Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, 143 005 Punjab, India
    Biochem Cell Biol 85:88-95. 2007
    ..In addition, Z. candida also exhibited significant anticancer activity against SNB-78, a CNS human cancer cell line...
  10. ncbi request reprint Antiviral activity of purified human breast milk mucin
    Habtom H Habte
    Department of Surgery, University of Cape Town, Cape Town, South Africa
    Neonatology 92:96-104. 2007
    ..4 million plaque-forming units/ml. As the milk mucin seems to aggregate poxviruses prior to their entry into host cells, it is possible that this mucin may also inhibit other enveloped viruses such as HIV from entry into host cells...
  11. ncbi request reprint In vitro mutagenicity studies of the antiretrovirals AZT, Didanosine, and 3TC and a plant antiviral extract Secomet-V derived from the Trifollium species
    Michela Ballardin
    Dipartimento di Scienze dell Uomo e dell Ambiente, University of Pisa, Italy
    Ann N Y Acad Sci 1056:303-10. 2005
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