Successful en bloc resection of primary hepatocellular carcinoma directly invading the stomach and pancreasDimitris P Korkolis
Department of Surgical Oncology, Hellenic Anticancer Institute, Saint Savvas Hospital, 22 Socratous Street, 1st Floor, Kifissia, Athens 14561, Greece
World J Gastroenterol 15:1134-7. 2009
..Direct invasion of HCC into the GI tract is rarely encountered. Complete surgical resection should be considered in selected patients with an appropriate hepatic functional reserve...
Intravascular papillary endothelial hyperplasia (Masson's hemangioma) presenting as a soft-tissue sarcomaDimitris P Korkolis
Department of Surgical Oncology, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
Anticancer Res 25:1409-12. 2005
..A case of intravascular papillary endothelial hyperplasia clinically diagnosed and treated as a low-grade angiosarcoma, in a 60-year-old man, presenting with a mass in the left thigh, is reported...
Merkel cell carcinoma: clinicopathological aspects of an unusual neoplasmI E Liapakis
Department of Plastic and Reconstructive Surgery, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
J BUON 12:173-9. 2007
..Such patients have a grim prognosis, with a median survival of 9 months. Successful outcome most often is seen in patients with early diagnosis and complete excision...
Short-term preoperative radiotherapy is a safe approach for treatment of locally advanced rectal cancerD P Korkolis
First Department of Surgery, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
Int J Colorectal Dis 21:1-6. 2006
..An increase in postoperative mortality and morbidity has also been observed, however. We therefore evaluated early postoperative complications in patients treated with neoadjuvant radiotherapy for locally advanced rectal adenocarcinoma...
Pre-operative chemoradiotherapy with oral capecitabine in locally advanced, resectable rectal cancerDimitris P Korkolis
First Department of Surgery, Hellenic Anticancer Institute, St Savvas Hospital, Athens, Greece
Anticancer Res 27:541-5. 2007
..The aim of the study was to evaluate the efficacy and tolerance of pre-operative chemoradiotherapy with oral capecitabine in Greek patients with locally advanced, resectable rectal cancer...
Dermatofibrosarcoma protuberans: clinicopathological aspects of an unusual cutaneous tumorD P Korkolis
First Department of Surgical Oncology, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
Anticancer Res 27:1631-4. 2007
..Mohs' micrographic surgery together with advanced reconstructive techniques provides satisfactory results even for tumors involving the face or distal extremities...
Primary malignant melanoma of the duodenum: aggressive management and long-term survival of an unusual oncologic entityDimitris P Korkolis
Department of Surgery, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
South Med J 101:836-9. 2008
..Primary malignant melanoma of the duodenum is an existing, though unusual, oncologic entity. Aggressive surgery remains the treatment of choice offering both symptom palliation and long-term survival...
Current assessment and management of spontaneous pneumomediastinum: experience in 24 adult patientsGeorge J Koullias
Section of Cardiothoracic Surgery, Yale New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA
Eur J Cardiothorac Surg 25:852-5. 2004
..The purpose of this study was to review our experience in dealing with this entity and detail a reasonable course of assessment and management...
Solitary fibrous tumor of the liver expressing CD34 and vimentin: a case reportDimitris P Korkolis
Department of Surgical Oncology, Hellenic Anticancer Institute, Saint Savvas Hospital, 22 Socratous Street, 1st Floor, Kifissia, 14561 Athens, Greece
World J Gastroenterol 14:6261-4. 2008
..With less than 30 reported cases in the literature, little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy. Complete surgical resection remains the cornerstone of its treatment...
Recombinant leptin administration improves early angiogenesis in full-thickness skin flaps: an experimental studyI E Liapakis
Department of Plastic and Reconstructive Surgery, Hellenic Anticancer Institute, Aghios Savvas Hospital, Athens, Greece
In Vivo 22:247-52. 2008
..In addition, leptin seems to play an important role in angiogenesis as it promotes the formation of new blood vessels...
Malignant hidradenoma: a report of two cases and review of the literatureI E Liapakis
Department of Plastic and Reconstructive Surgery, 2First Department of Surgical Oncology and 3Department of Surgical Pathology, Hellenic Anticancer Institute, Saint Savvas Hospital, Athens, Greece
Anticancer Res 26:2217-20. 2006
..Additional resection is generally required, with at least 2-cm clear margins, since surgery is the only effective treatment...
Mucocele of the appendiceal stump due to benign mucinous cystadenomaD P Korkolis
First Department of Surgery, Hellenic Anticancer Institute, St Savvas Hospital, Athens, Greece
Anticancer Res 26:635-8. 2006
..5 cm calcified tumor, which was excided together with the appendiceal remnant. Pathological diagnosis was that of a mucocele arising from the appendiceal stump due to the development of a benign mucinous cystadenoma...
Exogenously-administered leptin increases early incisional wound angiogenesis in an experimental animal modelI E Liapakis
Department of Plastic and Reconstructive Surgery and Saint Savvas Hospital, Athens, Greece
In Vivo 21:797-801. 2007
..In addition, leptin seems to play an important role in clinical angiogenesis by promoting the development of new blood vessels...
Tumor histology and stage but not p53, Her2-neu or cathepsin-D expression are independent prognostic factors in breast cancer patientsD P Korkolis
Department of Surgery, St Savvas Hospital, Athens, Greece
Anticancer Res 24:2061-8. 2004
..Additionally, our analysis indicates that deregulation of Her2-neu might characterize a subgroup of node-negative patients with poor prognosis who could benefit from an aggressive adjuvant therapy...
Dermatofibrosarcoma protuberans: a case series of 16 patients treated in a single institution with literature reviewMaria Archontaki
Department of Plastic and Reconstructive Surgery, Greek Anticancer Institute, St Savvas Hospital, Athens, Greece
Anticancer Res 30:3775-9. 2010
..Dermatofibrosarcoma protuberans is an uncommon skin tumour with a low to intermediate-grade of malignancy, characterized by progressive growth and a propensity for local recurrence...
Brief tamoxifen pretreatment enhances the chemosensitivity of gastric carcinoma cells to 5-fluorouracil in vitroGeorge J Koullias
Pinnacle Health Hospitals, Harrisburg, PA, USA
Anticancer Res 23:1575-80. 2003
..Several in vitro and in vivo studies examining the potential beneficial effects of adjuvant Tamoxifen (Tmx) have shown contradictory experimental and clinical results...
Tissue microarray detection of matrix metalloproteinases, in diseased tricuspid and bicuspid aortic valves with or without pathology of the ascending aortaGeorge J Koullias
Section of Cardiothoracic Surgery, Yale New Haven Hospital, New Haven, CT, USA
Eur J Cardiothorac Surg 26:1098-103. 2004
..The purpose of this study was to detect the presence of these enzymes in aortic valvular tissue in healthy and diseased aortic valves with or without the presence of synchronous ascending aortic pathology...
Early bioprosthetic mitral valve "pseudostenosis" after complete preservation of the native mitral apparatusDimitris P Korkolis
Department of Cardiothoracic Surgery, Yale-New Haven Hospital, Connecticut, USA
Ann Thorac Surg 74:1689-91. 2002
..This complication should be considered in patients in whom retention of the mitral valve apparatus has been performed. Such patients may benefit from long-term anticoagulation treatment to obviate this event...
Revascularization alone (without mitral valve repair) suffices in patients with advanced ischemic cardiomyopathy and mild-to-moderate mitral regurgitationGeorge A Tolis
Section of Cardiothoracic Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Ann Thorac Surg 74:1476-80; discussion 1480-1. 2002
..The improvement in MR likely results from improved left ventricular function and size consequent upon revascularization...