Affiliation: Yonsei University
Park J, Yun J, Shi Y, Han J, Li X, Jin Z, et al
. Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers. Int J Mol Sci. 2019;20: pubmed publisher
..The helix III region of the 140-153 residues near the active site and the DDE triad show a higher dynamic profile in the non-cryogenic structure, which is comparable to dynamics data obtained from NMR spectroscopy in solution state. ..
Lee I, Choi S, Yun J, Seo S, Choi S, Choi K, et al
. Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5. Biochem Biophys Res Commun. 2017;485:584-590 pubmed publisher
..Molecular modeling based on NMR and X-ray crystallographic data yielded detailed information about the Dvl1/CXXC5 interaction, which will be useful for designing inhibitors. ..
Shrestha P, Yun J, Ko Y, Kim M, Bae Y, Lee W. C-terminal tail of NADPH oxidase organizer 1 (Noxo1) mediates interaction with NADPH oxidase activator (Noxa1) in the NOX1 complex. Biochem Biophys Res Commun. 2017;490:594-600 pubmed publisher
Shrestha P, Yun J, Ko Y, Yeon K, Kim D, Lee H, et al
. NMR uncovers direct interaction between human NEDD4-1 and p34SEI-1. Biochem Biophys Res Commun. 2017;490:984-990 pubmed publisher
..Our data will provide insights into the molecular mechanism of NEDD4-1 and p34SEI-1 interaction, which will be directly used for drug design which inhibits the molecular interaction involved in different cancer signaling. ..