Weontae Lee


Affiliation: Yonsei University
Country: Korea


  1. Park J, Yun J, Shi Y, Han J, Li X, Jin Z, et al. Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers. Int J Mol Sci. 2019;20: pubmed publisher
    ..The helix III region of the 140-153 residues near the active site and the DDE triad show a higher dynamic profile in the non-cryogenic structure, which is comparable to dynamics data obtained from NMR spectroscopy in solution state. ..
  2. Lee I, Choi S, Yun J, Seo S, Choi S, Choi K, et al. Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5. Biochem Biophys Res Commun. 2017;485:584-590 pubmed publisher
    ..Molecular modeling based on NMR and X-ray crystallographic data yielded detailed information about the Dvl1/CXXC5 interaction, which will be useful for designing inhibitors. ..
  3. Shrestha P, Yun J, Ko Y, Kim M, Bae Y, Lee W. C-terminal tail of NADPH oxidase organizer 1 (Noxo1) mediates interaction with NADPH oxidase activator (Noxa1) in the NOX1 complex. Biochem Biophys Res Commun. 2017;490:594-600 pubmed publisher
  4. Shrestha P, Yun J, Ko Y, Yeon K, Kim D, Lee H, et al. NMR uncovers direct interaction between human NEDD4-1 and p34SEI-1. Biochem Biophys Res Commun. 2017;490:984-990 pubmed publisher
    ..Our data will provide insights into the molecular mechanism of NEDD4-1 and p34SEI-1 interaction, which will be directly used for drug design which inhibits the molecular interaction involved in different cancer signaling. ..