M G Lee

Summary

Affiliation: Yonsei University
Country: Korea

Publications

  1. ncbi Coordination of pancreatic HCO3- secretion by protein-protein interaction between membrane transporters
    M G Lee
    Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea
    JOP 2:203-6. 2001
  2. ncbi Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3- exchange in mouse submandibular and pancreatic ducts
    M G Lee
    Department of Pharmacology, Yonsei University College of Medicine, Seoul 120 752, Korea
    J Biol Chem 274:14670-7. 1999
  3. ncbi Regulatory interaction between the cystic fibrosis transmembrane conductance regulator and HCO3- salvage mechanisms in model systems and the mouse pancreatic duct
    W Ahn
    Department of Pharmacology and Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul 120 752, Korea
    J Biol Chem 276:17236-43. 2001
  4. ncbi Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects
    Y J Lee
    Department of Pharmacology, College of Medicine, Yonsei University, Seoul, Korea
    Int J Clin Pharmacol Ther 48:36-45. 2010
  5. ncbi Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct
    M G Lee
    Department of Pharmacology, College of Medicine, Yonsei University, Seoul, Korea
    J Clin Invest 105:1651-8. 2000
  6. ncbi Rifampin enhances the glucose-lowering effect of metformin and increases OCT1 mRNA levels in healthy participants
    S K Cho
    Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea
    Clin Pharmacol Ther 89:416-21. 2011
  7. ncbi Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells
    J H Shin
    The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea
    Acta Physiol (Oxf) 191:99-110. 2007
  8. ncbi Isolated splenic metastasis from colorectal carcinoma: a case report
    J C Kim
    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
    J Korean Med Sci 15:355-8. 2000
  9. ncbi Virulent Treponema pallidum 47 kDa antigen regulates the expression of cell adhesion molecules and binding of T-lymphocytes to cultured human dermal microvascular endothelial cells
    K H Lee
    Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 41:623-33. 2000
  10. ncbi Efficiency of combined colonoscopy and computed tomography for diagnosis of colonic actinomycosis: a retrospective evaluation of eight consecutive patients
    J C Kim
    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
    Int J Colorectal Dis 15:236-42. 2000

Detail Information

Publications23

  1. ncbi Coordination of pancreatic HCO3- secretion by protein-protein interaction between membrane transporters
    M G Lee
    Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea
    JOP 2:203-6. 2001
    ..These findings reveal that protein complexes in the plasma membrane of pancreatic duct cells are highly organized for efficient HCO(3)(-) secretion...
  2. ncbi Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3- exchange in mouse submandibular and pancreatic ducts
    M G Lee
    Department of Pharmacology, Yonsei University College of Medicine, Seoul 120 752, Korea
    J Biol Chem 274:14670-7. 1999
    ..We conclude that CFTR regulates luminal Cl-/HCO3- exchange activity in CFTR-expressing cells, and we discuss the possible physiological significance of these findings regarding cystic fibrosis...
  3. ncbi Regulatory interaction between the cystic fibrosis transmembrane conductance regulator and HCO3- salvage mechanisms in model systems and the mouse pancreatic duct
    W Ahn
    Department of Pharmacology and Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul 120 752, Korea
    J Biol Chem 276:17236-43. 2001
    ..These findings reveal that CFTR controls overall HCO3- homeostasis by regulating both pancreatic ductal HCO3- secretory and salvage mechanisms...
  4. ncbi Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects
    Y J Lee
    Department of Pharmacology, College of Medicine, Yonsei University, Seoul, Korea
    Int J Clin Pharmacol Ther 48:36-45. 2010
    ..This study aimed to evaluate the effect of genetic polymorphisms of SLCO1B1 and ABCB1 on the pharmacokinetics of atorvastatin and its metabolites...
  5. ncbi Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct
    M G Lee
    Department of Pharmacology, College of Medicine, Yonsei University, Seoul, Korea
    J Clin Invest 105:1651-8. 2000
    ..Inhibition of the transporters during stimulated secretion aids in producing the HCO(3)(-)-rich pancreatic juice...
  6. ncbi Rifampin enhances the glucose-lowering effect of metformin and increases OCT1 mRNA levels in healthy participants
    S K Cho
    Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea
    Clin Pharmacol Ther 89:416-21. 2011
    ..1-fold in peripheral blood cells (P = 0.001); however, OCT2 mRNA was not detected. Our results suggest that rifampin increases OCT1 expression and hepatic uptake of metformin, leading to enhanced glucose-lowering action...
  7. ncbi Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells
    J H Shin
    The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea
    Acta Physiol (Oxf) 191:99-110. 2007
    ..The aim of this study was to investigate the regulation of AE mRNA expression level in accordance with mucociliary differentiation and the functional expression of AEs cultured normal human nasal epithelial (NHNE) cells...
  8. ncbi Isolated splenic metastasis from colorectal carcinoma: a case report
    J C Kim
    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
    J Korean Med Sci 15:355-8. 2000
    ..As all reported cases showed elevated serum CEA at the time of metastasis, isolated splenic metastasis might be associated with CEA in regard to its biological functions of immunosuppression and adhesion...
  9. ncbi Virulent Treponema pallidum 47 kDa antigen regulates the expression of cell adhesion molecules and binding of T-lymphocytes to cultured human dermal microvascular endothelial cells
    K H Lee
    Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 41:623-33. 2000
    ..The whole process may play an important role in the immunopathogenesis of syphilis and it is likely that TNF-alpha and IL-1alpha are involved...
  10. ncbi Efficiency of combined colonoscopy and computed tomography for diagnosis of colonic actinomycosis: a retrospective evaluation of eight consecutive patients
    J C Kim
    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
    Int J Colorectal Dis 15:236-42. 2000
    ..A combination of colonoscopy and CT appears to be important for both diagnosis and management because of their compensatory findings of mucosal and extramucosal lesions, respectively...
  11. ncbi Extramammary Paget's disease with aggressive behavior: a report of two cases
    J C Kim
    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
    J Korean Med Sci 14:223-6. 1999
    ..Because wide local excision of the lesion alone may be occasionally insufficient, a careful follow-up must be done to detect recurrence or internal malignancy...
  12. ncbi Intracellular calcium mobilization induces immediate early gene pip92 via Src and mitogen-activated protein kinase in immortalized hippocampal cells
    K C Chung
    Department of Pharmacology and Brain Research Institute, Yonsei University College of Medicine, Seoul 120 752, Korea
    J Biol Chem 276:2132-8. 2001
    ....
  13. ncbi Association of ABCB1 polymorphisms with the efficacy of ondansetron for postoperative nausea and vomiting
    E M Choi
    Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea
    Anaesthesia 65:996-1000. 2010
    ..In conclusion, ABCB1 genotypes may be a clinical predictor of responsiveness for ondansetron...
  14. ncbi The cholecystokinin receptor antagonist L-364,718 reduces taurocholate-induced pancreatitis in rats
    K H Kim
    Department of Pharmacology, Yonsei University, College of Medicine, Seoul, Korea
    Int J Pancreatol 20:205-11. 1996
    ....
  15. ncbi Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae
    H K Song
    Department of Chemistry College of Natural Sciences, Seoul National University, Seoul, 151 742, Korea
    J Mol Biol 293:753-61. 1999
    ..This study sheds light on the best characterized eukaryotic phosphorelay system...
  16. ncbi Gastric schwannomas: radiological features with endoscopic and pathological correlation
    H S Hong
    Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seodaemoon Gu, Seoul, Korea
    Clin Radiol 63:536-42. 2008
    ..To describe the radiological, endoscopic, and pathological findings of gastric schwannomas in 16 patients...
  17. ncbi Heterogeneity in the processing defect of SLC26A4 mutants
    J S Yoon
    Department of Pharmacology and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    J Med Genet 45:411-9. 2008
    ....
  18. ncbi Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans
    J H Choi
    Department of Pharmacology, Yonsei University College of Medicine, Seoul, Korea
    Clin Pharmacol Ther 83:251-7. 2008
    ....
  19. ncbi DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-kappaB
    S Lee
    Department of Pharmacology, Kyungpook National University Medical School, Daegu, Korea
    Cell Biol Toxicol 23:105-12. 2007
    ..Our in vitro studies provide evidence that DA-9601 might contribute to the treatment of mast cell-derived allergic inflammatory diseases...
  20. ncbi Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses
    M G Lee
    School of Life Sciences and Biotechnology, Korea University, Seoul, Korea
    Oncogene 25:5807-22. 2006
    ....
  21. ncbi Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release
    M G Lee
    Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea
    Biol Pharm Bull 24:303-6. 2001
    ..Our data indicate that costunolide induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release. This is the first report on the mechanism of the anticancer effect of costunolide...
  22. ncbi ELISA inhibition test using monoclonal antibody specific for Treponema pallidum as the serologic test for syphilis
    K K Whang
    Department of Dermatology, Ewha Womans University College of Medicine, Seoul, Korea
    Acta Derm Venereol 75:397-9. 1995
    ..VDRL and TPHA titers were correlated with the percentage inhibitions. Therefore the ELISA inhibition test using Mab specific for T. pallidum might well be a suitable tool as a new serologic test for syphilis...
  23. ncbi Detection of Treponema pallidum in tissue: a comparative study of the avidin-biotin-peroxidase complex, indirect immunoperoxidase, FTA-ABS complement techniques and the darkfield method
    W S Lee
    Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 32:335-41. 1991
    ..Histologically, most of the treponemes were located in the upper dermis, epidermis and vessel walls in the order named, and rarely in the lower dermis of the syphilitic skin lesions...