Research Topics
| Hwan Young LeeSummaryAffiliation: Yonsei University College of Medicine Country: Korea Publications
| Collaborators
|
Detail Information
Publications
Body fluid identification in forensicsJa Hyun An
Department of Forensic Medicine, Yonsei University College of Medicine, Yonsei University, Seoul, Korea
BMB Rep 45:545-53. 2012..In this review, we provide an overview of the present knowledge and the most recent developments in forensic body fluid identification and discuss its possible practical application to forensic casework...
Potential forensic application of DNA methylation profiling to body fluid identificationHwan Young Lee
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120 752, South Korea
Int J Legal Med 126:55-62. 2012....
mtDNAmanager: a Web-based tool for the management and quality analysis of mitochondrial DNA control-region sequencesHwan Young Lee
Department of Forensic Medicine, Yonsei University College of Medicine, Seoul, Korea
BMC Bioinformatics 9:483. 2008..However, recent research has shown that using mtDNA phylogeny and referring to known mtDNA haplotypes can be useful for checking the quality of sequence data...- Mitochondrial DNA control region sequences in Koreans: identification of useful variable sites and phylogenetic analysis for mtDNA data quality controlHwan Young Lee
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, College of Medicine, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, 120-752, Seoul, South Korea
Int J Legal Med 120:5-14. 2006..8%) into various East Asian haplogroups or sub-haplogroups. Haplogroup-directed database comparisons confirmed the absence of any major systematic errors in our data, e.g., a mix-up of site designations, base shifts or mistypings... - Forensic evaluation and haplotypes of 19 Y-chromosomal STR loci in KoreansMyung Jin Park
Department of Forensic Medicine, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
Forensic Sci Int 152:133-47. 2005..These results including the haplotype data at 19 Y-STR loci in the present study would provide useful information in forensic practice in a Korean population... - Genetic characterization and assessment of authenticity of ancient Korean skeletal remainsHwan Young Lee
Department of Forensic Medicine and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul 120 752, Korea
Hum Biol 80:239-50. 2008.... - East Asian mtDNA haplogroup determination in Koreans: haplogroup-level coding region SNP analysis and subhaplogroup-level control region sequence analysisHwan Young Lee
Department of Forensic Medicine, Yonsei University College of Medicine, Seoul, Korea
Electrophoresis 27:4408-18. 2006.... - Rapid direct PCR for ABO blood typingHwan Young Lee
Department of Forensic Medicine, Yonsei University College of Medicine, Seodaemun gu, Seoul, Korea
J Forensic Sci 56:S179-82. 2011.... - Population data of nine miniSTR loci in KoreansUkhee Chung
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 134 Sinchon dong, Seodaemun gu, Seoul 120 752, Republic of Korea
Forensic Sci Int 168:e51-3. 2007..These data demonstrated that D10S1248, D2S441, D22S1045, D14S1434, and D6S474 are as highly informative as the CODIS STRs suggesting that the miniSTRs could be useful for forensic analysis of degraded DNA... - Characterization of deletions in the DYS385 flanking region and null alleles associated with AZFc microdeletions in KoreansMyung Jin Park
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seodaemun gu, Seoul, Korea
J Forensic Sci 53:331-4. 2008..The DYS448 deletion appears relatively frequent in Asians... - DNA typing for the identification of old skeletal remains from Korean War victimsHwan Young Lee
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul 120 752, Korea
J Forensic Sci 55:1422-9. 2010..The present analysis emphasizes the value of mini- and Y-STR systems as well as an efficient DNA extraction method in DNA testing for the identification of old skeletal remains... - Y-STR analysis of degraded DNA using reduced-size ampliconsMyung Jin Park
Department of Forensic Medicine, Yonsei University College of Medicine, 134 Sinchon dong, Seodaemun gu, Seoul, 120 752, South Korea
Int J Legal Med 121:152-7. 2007..This comparison demonstrated that the new Y-miniplex sets can produce a better signal from degraded DNA than the AmpFlSTR Yfiler kit... - Haplotypes and mutation analysis of 22 Y-chromosomal STRs in Korean father-son pairsHwan Young Lee
Department of Forensic Medicine and BK21 Project for Medical Science, Yonsei University College of Medicine, 134 Sinchon dong, Seodaemun gu, Seoul, 120 752, South Korea
Int J Legal Med 121:128-35. 2007..36 x 10(-3) (95% ci 2.03-2.73 x 10(-33))... - Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in KoreansHwan Young Lee
Department of Forensic Medicine, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
Forensic Sci Int 148:107-12. 2005..905x10(-10) and 98.9%, respectively. The SNPs in this study offer a small but highly accurate database that will be an essential reference for SNP-based forensic application in the future... - Differential distribution of human mitochondrial DNA in somatic tissues and hairsHwan Young Lee
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, College of Medicine, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea
Ann Hum Genet 70:59-65. 2006..Each hair shaft may have a restricted or clonal set of mtDNA molecules derived from a discrete group of stem cells... - A modified mini-primer set for analyzing mitochondrial DNA control region sequences from highly degraded forensic samplesHwan Young Lee
Department of Forensic Medicine, Yonsei University College of Medicine, Yonsei University, Seoul, Korea
Biotechniques 44:555-6, 558. 2008.... - Mitochondrial DNA CA dinucleotide repeats in Koreans: the presence of length heteroplasmyUkhee Chung
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, College of Medicine Yonsei University, 134 Shinchon-dong Seodaemun-gu, 120-752 Seoul, Korea
Int J Legal Med 119:50-3. 2005..A total of 4 alleles with 4-7 repeat units were observed and the genetic diversity was estimated to be 0.5120 in 500 unrelated Koreans. Interestingly, three individuals showed two or three length variants, i.e. length heteroplasmy... - Understanding the Y chromosome variation in Korea--relevance of combined haplogroup and haplotype analysesMyung Jin Park
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul, 120 752, South Korea
Int J Legal Med 126:589-99. 2012..These high-resolution haplogroup and haplotype data will improve our understanding of regional Y-chromosome variation or recent migration routes and will also help to infer haplogroup background or common ancestry... - Population genetic study of four closely-linked X-STR trios in KoreansJeong Eun Sim
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
Mol Biol Rep 37:333-7. 2010..98, and 77.1% of all haplotypes showed a frequency less than 0.01. Therefore, the four closely-linked X-STR trios will contribute to complex kinship testing in Koreans... - Genetic polymorphism and haplotype analysis of 4 tightly linked X-STR duos in KoreansEun Jin Lim
Department of Forensic Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul, Korea
Croat Med J 50:305-12. 2009..To investigate genetic polymorphism and haplotypes of tightly linked X-chromosomal short tandem repeat (X-STR) clusters in Koreans... - Simple and highly effective DNA extraction methods from old skeletal remains using silica columnsHwan Young Lee
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul 120 752, Republic of Korea
Forensic Sci Int Genet 4:275-80. 2010..We have successfully used this modified technique to perform STR analysis for 55-year-old skeletal remains. The results of this study will contribute to solve the forensic cases dealing with skeletal remains... - A genetic investigation of Korean mummies from the Joseon DynastyNa Young Kim
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul, 120 752, Korea
Mol Biol Rep 38:115-21. 2011..The small size amplicon strategy and the authentication process in the present study will be effectively applicable to future genetic analyses of various forensic and ancient samples... - Genetic characteristics and population study of 4 X-chromosomal STRs in Koreans: evidence for a null allele at DXS9898Hwan Young Lee
Department of Forensic Medicine, College of Medicine, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, 120-752 Seoul, Korea
Int J Legal Med 118:355-60. 2004..The test of homogeneity between allele frequencies revealed that there are some discrepancies in allele distributions between Koreans and Germans... - DNA methylation-specific multiplex assays for body fluid identificationJa Hyun An
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul, 120 752, South Korea
Int J Legal Med 127:35-43. 2013..Although including more markers for body fluid identification might be necessary, this study adds to the support that body fluid identification by DNA methylation profiles could be a valuable tool for forensic analysis of body fluids... - Y-SNP miniplexes for East Asian Y-chromosomal haplogroup determination in degraded DNAMyung Jin Park
Department of Forensic Medicine and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul 120 752, South Korea
Forensic Sci Int Genet 7:75-81. 2013..3%), followed by haplogroups C3 (xC3c, C3d, C3e) (16.0%) and O3a3c1 (11.0%). These multiplex sets will be useful tools for Y-chromosomal haplogroup determination in anthropological and forensic studies of East Asian populations... - Forensic and genetic characterization of mtDNA from Pathans of PakistanAllah Rakha
Department of Forensic Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul, South Korea
Int J Legal Med 125:841-8. 2011..Data presented here may contribute to the accuracy of forensic mtDNA comparisons in the Pathans of Pakistan... - A one step multiplex PCR assay for rapid screening of East Asian mtDNA haplogroups on forensic samplesHwan Young Lee
Department of Forensic Medicine, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul, South Korea
Leg Med (Tokyo) 15:50-4. 2013..Therefore, it would be a simple, rapid, and reliable detection method useful for large-scale screening of mtDNA variations to determine East Asian mtDNA haplogroups... - Quantitative and qualitative profiling of mitochondrial DNA length heteroplasmyHwan Young Lee
Department of Forensic Medicine, College of Medicine, Seoul, Korea
Electrophoresis 25:28-34. 2004....