Ji Hoe Heo

Summary

Affiliation: Yonsei University
Country: Korea

Publications

  1. ncbi request reprint Free radicals as triggers of brain edema formation after stroke
    Ji Hoe Heo
    Department of Neurology, National Core Research Center for Nanomedical Technology, Brain Korea 21 Project for Medical Sciences, Seoul
    Free Radic Biol Med 39:51-70. 2005
  2. ncbi request reprint Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure
    Ji Hoe Heo
    Department of Neurology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Stroke 34:e48-50. 2003
  3. ncbi request reprint Immediate reocclusion following a successful thrombolysis in acute stroke: a pilot study
    Ji Hoe Heo
    Department of Neurology, Yonsei University College of Medicine, Brain Korea 21 Project, Seoul, Korea
    Neurology 60:1684-7. 2003
  4. doi request reprint The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea
    Atherosclerosis 219:887-91. 2011
  5. doi request reprint Safety and outcome after thrombolytic treatment in ischemic stroke patients with high-risk cardioembolic sources and prior subtherapeutic warfarin use
    Young Dae Kim
    Department of Neurology, Severance Hospital Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 298:101-5. 2010
  6. doi request reprint Prediction of long-term outcome by percent improvement after the first day of thrombolytic treatment in stroke patients
    Hyo Suk Nam
    Department of Neurology and National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, South Korea
    J Neurol Sci 281:69-73. 2009
  7. ncbi request reprint Early recanalization after intravenous administration of recombinant tissue plasminogen activator as assessed by pre- and post-thrombolytic angiography in acute ischemic stroke patients
    Kyung Yul Lee
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemoon ku, 120 752, Seoul, Korea
    Stroke 38:192-3. 2007
  8. doi request reprint Plasma osteoprotegerin levels increase with the severity of cerebral artery atherosclerosis
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea
    Clin Biochem 46:1036-40. 2013
  9. doi request reprint Stroke severity in concomitant cardiac sources of embolism in patients with atrial fibrillation
    Young Dae Kim
    Department of Neurology, Severance Hospital Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 298:23-7. 2010
  10. ncbi request reprint Mechanism of infarction involving ipsilateral carotid and posterior cerebral artery territories
    Jae Hoon Yang
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 24:445-51. 2007

Collaborators

Detail Information

Publications90

  1. ncbi request reprint Free radicals as triggers of brain edema formation after stroke
    Ji Hoe Heo
    Department of Neurology, National Core Research Center for Nanomedical Technology, Brain Korea 21 Project for Medical Sciences, Seoul
    Free Radic Biol Med 39:51-70. 2005
    ..The development of effective therapeutic strategies aimed at reducing brain edema based on targeting specific molecular pathways involved may reduce death and disability from stroke...
  2. ncbi request reprint Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure
    Ji Hoe Heo
    Department of Neurology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Stroke 34:e48-50. 2003
    ..Platelet-rich thrombi are resistant to thrombolytics. Matrix metalloproteinases (MMPs) may be involved in platelet aggregation and contribute to thrombolysis failure in stroke patients...
  3. ncbi request reprint Immediate reocclusion following a successful thrombolysis in acute stroke: a pilot study
    Ji Hoe Heo
    Department of Neurology, Yonsei University College of Medicine, Brain Korea 21 Project, Seoul, Korea
    Neurology 60:1684-7. 2003
    ..Rapid thrombotic reocclusion after successful thrombolysis is commonly observed in patients after an acute stroke. Administration of abciximab may lead to reperfusion of the reoccluded artery...
  4. doi request reprint The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea
    Atherosclerosis 219:887-91. 2011
    ..If present, we sought to determine whether the relationship differed between atherosclerosis in the intracranial artery and atherosclerosis in the extracranial artery...
  5. doi request reprint Safety and outcome after thrombolytic treatment in ischemic stroke patients with high-risk cardioembolic sources and prior subtherapeutic warfarin use
    Young Dae Kim
    Department of Neurology, Severance Hospital Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 298:101-5. 2010
    ..However, it remains uncertain whether the prior warfarin use actually increases their risk of bleeding in patients treated with thrombolysis...
  6. doi request reprint Prediction of long-term outcome by percent improvement after the first day of thrombolytic treatment in stroke patients
    Hyo Suk Nam
    Department of Neurology and National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, South Korea
    J Neurol Sci 281:69-73. 2009
    ..We investigated a method for assessing early improvement and predictive factors of early and late outcomes in patients receiving thrombolytic therapy...
  7. ncbi request reprint Early recanalization after intravenous administration of recombinant tissue plasminogen activator as assessed by pre- and post-thrombolytic angiography in acute ischemic stroke patients
    Kyung Yul Lee
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemoon ku, 120 752, Seoul, Korea
    Stroke 38:192-3. 2007
    ..Recanalization rates after the intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment have been poorly studied in acute stroke...
  8. doi request reprint Plasma osteoprotegerin levels increase with the severity of cerebral artery atherosclerosis
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea
    Clin Biochem 46:1036-40. 2013
    ..We investigated whether plasma OPG levels were associated with the presence and severity of cerebral atherosclerosis...
  9. doi request reprint Stroke severity in concomitant cardiac sources of embolism in patients with atrial fibrillation
    Young Dae Kim
    Department of Neurology, Severance Hospital Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 298:23-7. 2010
    ..We investigated among stroke patients with AF whether stroke severity is different between patients with concomitant potential cardiac sources of embolism and those without...
  10. ncbi request reprint Mechanism of infarction involving ipsilateral carotid and posterior cerebral artery territories
    Jae Hoon Yang
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 24:445-51. 2007
    ..We investigated the potential mechanism of infarction involving the territories of both the internal carotid artery (ICA) and the ipsilateral posterior cerebral artery (PCA)...
  11. ncbi request reprint Sequential combination of intravenous recombinant tissue plasminogen activator and intra-arterial urokinase in acute ischemic stroke
    Kyung Yul Lee
    Department of Neurology, BK21 Projects for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea
    AJNR Am J Neuroradiol 25:1470-5. 2004
    ..We prospectively evaluated the effectiveness and safety of sequential combination of IV rTPA and IA UK in acute ischemic stroke...
  12. pmc The influence of anti-platelet resistance on the development of cerebral ischemic lesion after carotid artery stenting
    Tae Jin Song
    Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju ro, Gangnam Gu, Seoul 135 720, Korea
    Yonsei Med J 54:288-94. 2013
    ..We, therefore, investigated the effects of anti-platelet resistance on the development of cerebral ischemic lesions after CAS...
  13. doi request reprint Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemoon ku, 120 752 Seoul, Republic of Korea
    Atherosclerosis 224:113-7. 2012
    ..We investigated whether low ABI is associated with long-term functional outcome in patients with acute cerebral infarction...
  14. doi request reprint Association of plasma osteoprotegerin levels with stroke severity and functional outcome in acute ischaemic stroke patients
    Tae Jin Song
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Biomarkers 17:738-44. 2012
    ..These results suggest pleiotropic roles of OPG in mediating atherosclerosis and ischaemic brain injury. OPG is a potential biomarker for predicting neurologic outcome in stroke...
  15. doi request reprint Different prognostic value of white blood cell subtypes in patients with acute cerebral infarction
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea
    Atherosclerosis 222:464-7. 2012
    ..We aimed to investigate the relationship of each white blood cells (WBC) subtype with neurologic severity and outcome in acute stroke...
  16. pmc Beneficial effects of stroke-unit care in stroke patients with atrial fibrillation
    Hye Yeon Choi
    Department of Neurology, Yonsei University College of Medicine, Kangdong Hospital, 50 Yonsei ro, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 54:301-5. 2013
    ..We investigated the effects of the SU on the detection of AF and the rate of warfarin therapy in patients with AF...
  17. doi request reprint Ischemic stroke: measurement of intracranial artery calcifications can improve prediction of asymptomatic coronary artery disease
    Sung Soo Ahn
    Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea
    Radiology 268:842-9. 2013
    ....
  18. doi request reprint The clinical syndrome and etiological mechanism of infarction involving the nucleus prepositus hypoglossi
    Hyun Ji Cho
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 26:178-83. 2008
    ..The present study investigated the clinical spectrum and etiological mechanism of isolated, small infarctions involving the NPH area demonstrated on MRI...
  19. doi request reprint Red blood cell distribution width is associated with poor clinical outcome in acute cerebral infarction
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Thromb Haemost 108:349-56. 2012
    ..RDW may be used as a biomarker for the prediction of long-term outcomes in patients with acute cerebral infarction...
  20. doi request reprint Transoesophageal echocardiography in patients with acute stroke with sinus rhythm and no cardiac disease history
    Hyun Ji Cho
    Department of Neurology, Yonsei University College of Medicine, 250 Seongsan no, Seodaemoon Gu, Seoul 120 752, Korea
    J Neurol Neurosurg Psychiatry 81:412-5. 2010
    ..However, the role of TOE in patients with ischaemic stroke with normal sinus rhythm (NSR) and no cardiac disease remains uncertain...
  21. ncbi request reprint A new subtype classification of ischemic stroke based on treatment and etiologic mechanism
    Sang Won Han
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, Republic of Korea
    Eur Neurol 57:96-102. 2007
    ..82). The new classification system for brain infarction was easy to use and had high inter-rater reliability...
  22. ncbi request reprint Paradoxically accelerated fatal brain herniation following thrombolytic therapy in acute ischemic stroke
    Sang Won Han
    Department of Neurology, National Core Research Center for Nanomedical Technology, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seodaemoon ku, Seoul, Korea
    Neurocrit Care 5:35-8. 2006
    ..The use of plasminogen activators (PAs) in acute stroke patients has dual effects. PAs are beneficial by dissolving thrombi occluding an artery, but may be harmful by their proteolytic and excitotoxic actions...
  23. doi request reprint Serum alkaline phosphatase and phosphate in cerebral atherosclerosis and functional outcomes after cerebral infarction
    Jinkwon Kim
    From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea J K Department of Neurology, Ewha Womans University, Seoul, Republic of Korea T J S and Departments of Neurology J K, D S, H S N, Y D K, J H H and Biostatistics H S L, C M N, Yonsei University College of Medicine, Seoul, Republic of Korea
    Stroke 44:3547-9. 2013
    ..However, the association of ALP/phosphate with cerebral atherosclerosis and prognosis in patients with acute stroke is not well known...
  24. ncbi request reprint Frequency and significance of cardiac sources of embolism in the TOAST classification
    Sang Won Han
    Department of Neurology, Sanggyepaik Hospital, Inje University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 24:463-8. 2007
    ....
  25. doi request reprint Interarm blood pressure difference and mortality in patients with acute ischemic stroke
    Jinkwon Kim
    Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam si, Korea
    Neurology 80:1457-64. 2013
    ..The objective of this study was to assess the prognostic value of interarm difference of blood pressure (IAD) measured in acute ischemic stroke and to investigate its association with systemic atherosclerosis...
  26. doi request reprint Characteristics and the fate of intraluminal thrombus of the intracranial and extracranial cerebral arteries in acute ischemic stroke patients
    Hye Yeon Choi
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, Korea
    Eur Neurol 62:72-8. 2009
    ..The characteristics and fate of intraluminal thrombus (IT), which may incidentally be detected in acute stroke patients, are not well known and the optimal treatment strategy for IT remains controversial...
  27. doi request reprint Increases in cerebral atherosclerosis according to CHADS2 scores in patients with stroke with nonvalvular atrial fibrillation
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, 250 Seongsan no, Seodaemoon Gu, Seoul, 120 752, Korea
    Stroke 42:930-4. 2011
    ..The aim of this study was to determine whether there are differences in the presence and burden of concomitant cerebral atherosclerosis according to CHADS(2) scores in patients with stroke with nonvalvular atrial fibrillation...
  28. doi request reprint Ischaemic cardiovascular mortality in patients with non-valvular atrial fibrillation according to CHADS₂ score
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Thromb Haemost 105:712-20. 2011
    ..The CHADS₂ and CHA₂DS₂-VASc scores provide valuable information for identifying high-risk individuals for fatal ischaemic heart and brain diseases among stroke patients with NVAF...
  29. doi request reprint Simple microwire and microcatheter mechanical thrombolysis with adjuvant intraarterial urokinase for treatment of hyperacute ischemic stroke patients
    Dong Joon Kim
    Department of Radiology, Yonsei University College of Medicine, Seoul, Korea
    Acta Radiol 49:351-7. 2008
    ..Mechanical thrombolysis may effectively enhance the efficacy of thrombolysis for hyperacute ischemic stroke patients...
  30. doi request reprint A computerized in-hospital alert system for thrombolysis in acute stroke
    Ji Hoe Heo
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Stroke 41:1978-83. 2010
    ....
  31. pmc Incremental Value of Left Atrial Global Longitudinal Strain for Prediction of Post Stroke Atrial Fibrillation in Patients with Acute Ischemic Stroke
    Darae Kim
    Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea
    J Cardiovasc Ultrasound 24:20-7. 2016
    ..For better risk stratification for post-stroke AF, we studied left atrial (LA) size and mechanical function using two-dimensional (2D) speckle tracking imaging in patients with acute ischemic stroke...
  32. pmc Association between Aortic Atheroma and Cerebral Small Vessel Disease in Patients with Ischemic Stroke
    Tae Jin Song
    Department of Neurology, Ewha Womans University College of Medicine, Seoul, Korea
    J Stroke 18:312-320. 2016
    ..This study evaluated the relationship between presence and burden of AAs and those of SVDs in patients with acute ischemic stroke...
  33. doi request reprint Prognostic value of urine dipstick proteinuria on mortality after acute ischemic stroke
    Jinkwon Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea Department of Neurology, Bundang Cha Medical Center, CHA University School of Medicine, Seongnam, South Korea
    Atherosclerosis 253:118-123. 2016
    ..This study was aimed at investigating the prognostic value of proteinuria measured by urine dipstick in patients with acute ischemic stroke...
  34. pmc Gray-Matter Volume Estimate Score: A Novel Semi-Automatic Method Measuring Early Ischemic Change on CT
    Dongbeom Song
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    J Stroke 18:80-6. 2016
    ..This study aimed to compare GRAVES and Alberta Stroke Program Early CT Score (ASPECTS) with regards to outcome prediction and inter-rater agreement...
  35. doi request reprint Time-Dependent Thrombus Resolution After Tissue-Type Plasminogen Activator in Patients With Stroke and Mice
    Young Dae Kim
    From the Department of Neurology Y D K, H S N, S H K, D S, K L, J Y, J H H, Severance Integrative Research Institutes for Cerebral and Cardiovascular Diseases I K, S H Y, Department of Biostatistics H S L, Yonsei University College of Medicine, Seoul, Korea Department of Neurology, Yonsei Wonju University College of Medicine, Wonju, Korea S H K and Department of Radiology, Gachon University, Gil Medical Center, Incheon, Korea E Y K
    Stroke 46:1877-82. 2015
    ..We investigated the relationship between the degree of thrombus resolution and the time from stroke onset or thrombus formation to intravenous tissue-type plasminogen activator (tPA) treatment...
  36. doi request reprint Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke
    Jinkwon Kim
    From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi Do, Korea J K Department of Neurology, Ewha Womans University, Seoul, Korea T J S and Departments of Neurology J K, E H K, K J L, D S, H S N, Y D K, J H H and Biostatistics H S L, C M N, Yonsei University College of Medicine, Seoul, Korea
    Stroke 45:2305-10. 2014
    ..We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes...
  37. pmc Lack of association between stroke and left atrial out-pouching structures: results of a case-control study
    Ji Young Ko
    Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    PLoS ONE 8:e76617. 2013
    ..Clinical significance of out-pouching structures of the left atrium (LA) as potential embolic sources remains unclear. We sought to evaluate the association between stroke and LA out-pouching structures...
  38. doi request reprint Incidence of embolism associated with carotid artery stenting: open-cell versus closed-cell stents
    Keun Young Park
    Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurosurg 119:642-7. 2013
    ..The purpose of this study was to evaluate the influence of stent design on the incidence of procedural and postprocedural embolism associated with CAS treatment...
  39. doi request reprint The frequency and risk of preclinical coronary artery disease detected using multichannel cardiac computed tomography in patients with ischemic stroke
    Joonsang Yoo
    Department of Neurology, Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Yonsei University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 33:286-94. 2012
    ..However, association between coronary and cerebral artery atherosclerosis in stroke patients has not fully been investigated. This study aimed at examining the frequency and high-risk groups of CAD in ischemic stroke patients...
  40. ncbi request reprint Chronic cerebral hypoperfusion protects against acute focal ischemia, improves motor function, and results in vascular remodeling
    Seo Hyun Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Curr Neurovasc Res 5:28-36. 2008
    ..05). Strokes were less severe when the vicinity subjected to infarction was preconditioned with chronic cerebral hypoperfusion. Increasing the vascular reserve with adaptive vascular remodeling may have contributed to this response...
  41. doi request reprint Classic risk factors for atherosclerosis are not major determinants for location of extracranial or intracranial cerebral atherosclerosis
    Young Dae Kim
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, Korea
    Neuroepidemiology 32:201-7. 2009
    ..This study aimed to determine if there are any specific risk factors for EC or IC atherosclerosis...
  42. pmc Increasing frequency and burden of cerebral artery atherosclerosis in Korean stroke patients
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, 250 Seongsan ro, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 51:318-25. 2010
    ..This study was aimed at determining the frequency and distribution of atherosclerosis in the cerebral arteries and associated temporal changes over the past eight-year period among Korean stroke patients...
  43. ncbi request reprint Improved time intervals by implementation of computerized physician order entry-based stroke team approach
    Hyo Suk Nam
    Department of Neurology, National Core Research Center for Nanomedical Technology, Brain Korea 21 Project for Medical Sciences, Ajou University School of Medicine, Suwon, Republic of Korea
    Cerebrovasc Dis 23:289-93. 2007
    ..A computerized physician order entry (CPOE) system can improve communication and provide immediate access to information, which may be useful for an effective team approach program targeted to reduce in-hospital time delays...
  44. ncbi request reprint Rescue localized intra-arterial thrombolysis for hyperacute MCA ischemic stroke patients after early non-responsive intravenous tissue plasminogen activator therapy
    Dong Joon Kim
    Department of Diagnostic Radiology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul, 120 752, South Korea
    Neuroradiology 47:616-21. 2005
    ..In conclusion, rescue LIT therapy can be considered as a treatment option for patients not showing early response to full dose i.v. tPA therapy. Larger scale studies for further validation of this protocol may be necessary...
  45. pmc Effect and Safety of Rosuvastatin in Acute Ischemic Stroke
    Ji Hoe Heo
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    J Stroke 18:87-95. 2016
    ..However, statins may increase the risk of intracerebral hemorrhage. We investigated the effect and safety of rosuvastatin in acute stroke patients...
  46. doi request reprint Comprehensive code stroke program to reduce reperfusion delay for in-hospital stroke patients
    Joonsang Yoo
    Department of Neurology, Severance Stroke Center, Yonsei University College of Medicine, Seoul, Korea
    Int J Stroke 11:656-62. 2016
    ..Stroke may occur during hospital admission (in-hospital stroke). Although patients with in-hospital stroke are potentially good candidates for reperfusion therapy, they often do not receive treatment as rapidly as expected...
  47. doi request reprint Poor Outcome of Stroke Patients With Atrial Fibrillation in the Presence of Coexisting Spontaneous Echo Contrast
    Joonsang Yoo
    From the Department of Neurology J Y, D S, J H B, Y D K, H S N, J K, J H H, Cardiology Division, Severance Cardiovascular Hospital G R H, and Biostatistics Collaboration Unit H S L, Yonsei University College of Medicine, Seoul, Korea and Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Korea J K
    Stroke 47:1920-2. 2016
    ..Spontaneous echo contrast (SEC) is frequently detected in patients with atrial fibrillation (AF). Coexisting SEC in patients with AF may be associated with heightened thrombogenicity, which affects stroke outcomes...
  48. doi request reprint Value of utilizing both ASPECTS and CT angiography collateral score for outcome prediction in acute ischemic stroke
    Dongbeom Song
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Int J Stroke 10:1018-23. 2015
    ..Alberta Stroke Program Early CT Score (ASPECTS) represents the extent of irreversibly damaged tissue; while CT angiography collateral score (CTA-CS) denotes the degree of collaterals...
  49. pmc Impact of temporary opening using a stent retriever on clinical outcome in acute ischemic stroke
    Dongbeom Song
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    PLoS ONE 10:e0124551. 2015
    ..We investigated if temporary opening of occluded vessels using a stent retriever before final reperfusion might improve clinical outcome in acute ischemic stroke patients who received the endovascular reperfusion treatment...
  50. pmc Factors associated with ischemic stroke on therapeutic anticoagulation in patients with nonvalvular atrial fibrillation
    Young Dae Kim
    Department of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 56:410-7. 2015
    ..In this study, we investigated the stroke mechanism and the factors associated with ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF) who were on optimal oral anticoagulation with warfarin...
  51. pmc Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice
    Il Kwon
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea
    PLoS ONE 8:e81165. 2013
    ..Saxatilin inhibited multiple integrins by acting on platelets, and was safe and effective in resolving thrombi in mice. ..
  52. doi request reprint Predicting asymptomatic coronary artery disease in patients with ischemic stroke and transient ischemic attack: the PRECORIS score
    David Calvet
    From Paris Descartes University, Centre de Psychiatrie et Neurosciences INSERM UMR 894, Paris, France D C, G T, J L M Department of Neurology, Centre Hospitalier Sainte Anne, Paris, France D C, G T, J L M Departments of Neurology D S, J Y, J H H and Radiology B W C, Yonsei University College of Medicine, Seoul, Korea and Department of Radiology, Centre Cardiolique du Nord, Saint Denis, France J L S
    Stroke 45:82-6. 2014
    ..Identifying occult coronary artery stenosis may improve secondary prevention of stroke patients. The aim of this study was to derive and validate a simple score to predict severe occult coronary artery stenosis in stroke patients...
  53. doi request reprint Long-term mortality in patients with stroke of undetermined etiology
    Hyo Suk Nam
    Department of Neurology, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul, 120 752, Korea
    Stroke 43:2948-56. 2012
    ..The determination of stroke etiology is essential for planning treatment for stroke prevention. However, the etiology of stroke is undetermined in many patients...
  54. doi request reprint Determinants of infarction patterns in cardioembolic stroke
    Young Dae Kim
    Department of Neurology, Severance Hospital Integrative Research Institute for Cerebral and Cardiovascular Diseases, Seoul, Korea
    Eur Neurol 66:145-50. 2011
    ..However, it remains unknown which factors contribute to these different infarction patterns in patients with potential cardiac sources of embolism (PCSE)...
  55. doi request reprint Carotid stenting in acute ischemic stroke patients with intraluminal thrombus
    Tai Hyung Kwon
    Department of Radiology, Yonsei University College of Medicine, 250 Seongsanno, Seoul, 120 752, South Korea
    Neuroradiology 53:773-8. 2011
    ..We evaluated the feasibility and outcome of carotid stenting in acute ischemic stroke patients with carotid stenosis and intraluminal thrombus...
  56. pmc Increased Risk of Cardiovascular Events in Stroke Patients Who had Not Undergone Evaluation for Coronary Artery Disease
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 58:114-122. 2017
    ..We compared long-term cardio-cerebrovascular outcomes between patients who underwent MDCT and those who did not...
  57. doi request reprint D-dimer for prediction of long-term outcome in cryptogenic stroke patients with patent foramen ovale
    Young Dae Kim
    Ji Hoe Heo, MD, PhD, Department of Neurology, Yonsei University College of Medicine, 50 1 Yonsei ro, Seodaemoon Gu, Seoul, 120 752, Korea, Tel 82 2 2228 1605, Fax 82 2 393 0705, E mail
    Thromb Haemost 114:614-22. 2015
    ..The coexistence of PFO and a high D-dimer level increased the risk of recurrent ischaemic stroke. The D-dimer test in cryptogenic stroke patients may be useful for predicting outcomes and deciding treatment strategy. ..
  58. doi request reprint Long-term mortality in patients with coexisting potential causes of ischemic stroke
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Int J Stroke 10:541-6. 2015
    ..Multiple potential causes of stroke may coexist in ischemic stroke patients, which may affect long-term outcome...
  59. doi request reprint Incidence and risk factors for diffusion-weighted imaging (+) lesions after intracranial stenting and its relationship with symptomatic ischemic complications
    Keun Young Park
    From the Departments of Neurosurgery K Y P, Radiology B M K, D J K, D I K, and Neurology J H H, H S N, Y D K, D S, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea
    Stroke 45:3298-303. 2014
    ..This study aimed to evaluate the incidence, distribution, risk factors, and clinical implications of DWI (+) after intracranial stenting...
  60. doi request reprint Fc-saxatilin, a snake venom disintegrin, suppresses hypoxia-induced vascular leakage by regulating endothelial occludin expression
    Hyun Jung Choi
    Ji Hoe Heo, MD, PhD, Department of Neurology, Yonsei University College of Medicine, 50 1 Yonsei ro, Seodaemun gu, Seoul, 120 752, Republic of Korea, Tel 82 2 2228 1605, Fax 82 2 2227 7906, E mail
    Thromb Haemost . 2016
    ....
  61. doi request reprint Timely Interventions can Increase Smoking Cessation Rate in Men with Ischemic Stroke
    Min Jeong Lee
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    J Korean Acad Nurs 46:610-7. 2016
    ..The aim of this study was to demonstrate the usefulness of the timely interventions for smoking cessation in men with acute ischemic stroke...
  62. doi request reprint The Ischemic Stroke Predictive Risk Score Predicts Early Neurological Deterioration
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Stroke Cerebrovasc Dis 25:819-24. 2016
    ..The aim of this study was to investigate whether there are differences in the occurrence of END according to the ischemic stroke predictive risk score (iScore), which was developed to predict short- and long-term mortality...
  63. pmc The Computerized Table Setting Test for Detecting Unilateral Neglect
    Seok Jong Chung
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    PLoS ONE 11:e0147030. 2016
    ..To facilitate the evaluation of unilateral spatial neglect, we developed a new application that runs on a tablet device and investigated its feasibility in stroke patients...
  64. doi request reprint Association of cerebral microbleeds with mortality in stroke patients having atrial fibrillation
    Tae Jin Song
    From the Departments of Neurology T J S, D S, H S N, Y D K, J H H and Biostatistics H S L, Yonsei University College of Medicine, Seoul Department of Neurology T J S, Ewha Womans University School of Medicine, Seoul and Department of Neurology J K, CHA Bundang Medical Centre, CHA University, Seongnam, Korea
    Neurology 83:1308-15. 2014
    ..We investigated the association of cerebral microbleeds (CMBs) with long-term mortality in patients with nonvalvular atrial fibrillation (NVAF) according to burden and distribution of CMBs...
  65. pmc Long-term mortality according to the characteristics of early neurological deterioration in ischemic stroke patients
    Young Dae Kim
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Yonsei Med J 55:669-75. 2014
    ..The aim of this study was to investigate whether there are differences in long-term mortality according to the characteristics of END among acute ischemic stroke or transient ischemic attack patients...
  66. pmc Development of smartphone application that aids stroke screening and identifying nearby acute stroke care hospitals
    Hyo Suk Nam
    Department of Neurology, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 55:25-9. 2014
    ..The benefits of thrombolytic treatment are time-dependent. We developed a smartphone application that aids stroke patient self-screening and hospital selection, and may also decrease hospital arrival time...
  67. doi request reprint Quantification of intracranial internal carotid artery calcification on brain unenhanced CT: evaluation of its feasibility and assessment of the reliability of visual grading scales
    Sung Soo Ahn
    Department of Radiology and the Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea
    Eur Radiol 23:20-7. 2013
    ..The purpose of this study was to evaluate the feasibility of ICAC volume measurement and to correlate the volume with visual grading scales...
  68. doi request reprint Stroke units and stroke care services in Korea
    Hye Yeon Choi
    Department of Neurology, Kyung Hee University College of Medicine, Kangdong Hospital, Seoul, Korea
    Int J Stroke 7:336-40. 2012
    ..However, stroke units have not been widely implemented. Encouragement and support at the government or national stroke society level would promote the implementation of stroke units with little additional effort...
  69. pmc Mechanism of medullary infarction based on arterial territory involvement
    Kyoungsub Kim
    Department of Neurology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea
    J Clin Neurol 8:116-22. 2012
    ..The blood supply to the medulla oblongata is distinct from that of other areas of the brainstem, and thus the mechanism underlying medullary infarctions may be distinct. However, few studies have investigated this...
  70. doi request reprint Clinical significance of anti-annexin V antibody in acute cerebral ischemia
    Kee Ook Lee
    Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 305:53-6. 2011
    ..We investigated the clinical significance of the anti-annexin V antibody (aAV) in patients with acute cerebral ischemia; annexin V promotes anticoagulant activity via inhibition of prothrombin activation...
  71. doi request reprint Cortex-sparing infarctions in patients with occlusion of the middle cerebral artery
    Han Jin Cho
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    J Neurol Neurosurg Psychiatry 81:859-63. 2010
    ..In patients with a middle cerebral artery (MCA) occlusion, the involvement of the cortex may be affected by the presence of leptomeningeal anastomoses between the cerebral arteries...
  72. doi request reprint Clinical manifestations of cerebellar infarction according to specific lobular involvement
    Byoung Seok Ye
    Department of Neurology, Yonsei University College of Medicine, 250 Seongsanno, Seoul, 120 752, South Korea
    Cerebellum 9:571-9. 2010
    ..Our results showed that the cerebellar lobules are responsible for producing specific symptoms in cerebellar stroke patients...
  73. ncbi request reprint Predictive implications of recurrent transient ischemic attacks in large-artery atherosclerosis
    Seo Hyun Kim
    Department of Neurology, National Core Research Center for Nanomedical Technology, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea
    Cerebrovasc Dis 22:240-4. 2006
    ..It is uncertain whether recurrent transient ischemic attacks (R-TIAs), when comparing with single TIAs (S-TIAs), have any distinct mechanisms...
  74. ncbi request reprint Preconditioning with chronic cerebral hypoperfusion reduces a focal cerebral ischemic injury and increases apurinic/apyrimidinic endonuclease/redox factor-1 and matrix metalloproteinase-2 expression
    Sun Ah Choi
    Department of Neurology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemoon Gu, Seoul, 120 752, Korea
    Curr Neurovasc Res 4:89-97. 2007
    ..These findings provide experimental evidence that chronic cerebral hypoperfusion would be protective against subsequent severe ischemic insults...
  75. ncbi request reprint Detection of thrombus in acute ischemic stroke: value of thin-section noncontrast-computed tomography
    Eung Yeop Kim
    Department of Radiology, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea
    Stroke 36:2745-7. 2005
    ..The purpose of this study was to compare thin-section NCT with 5-mm NCT in the detection of thrombus in acute ischemic stroke...
  76. doi request reprint Contraversive ocular tilt reaction after the lateral medullary infarction
    Kyoo Ho Cho
    Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
    Neurologist 19:79-81. 2015
    ..A lateral medullary infarction usually causes ipsiversive OTR. This is the first report of contraversive OTR following the lateral medullary infarction...
  77. ncbi request reprint The usefulness of fractional anisotropy maps in localization of lacunar infarctions in striatum, internal capsule and thalamus
    Hyun Kyung Jeong
    Department of Radiology and Research, Institute of Radiological Sciences, Yonsei University College of Medicine, Seodaemungu, Seoul 120 752, Korea
    Neuroradiology 47:267-70. 2005
    ..Clinical presentation varies according to the exact location of lacunar infarctions, and more accurate diagnosis can be made by FA maps as well as conventional T2-weighted image and DWI...
  78. ncbi request reprint Rescue collateral flow in color duplex sonography
    Sang Won Han
    Department of Neurology, National Core Research Center for Nanomedical Sciences, Seoul, Korea
    J Ultrasound Med 24:1137-9. 2005
  79. pmc An objective pronator drift test application (iPronator) using handheld device
    Soojeong Shin
    Department of Neurology, Yonsei University College of Medicine, Seodaemoon Gu, Seoul, Korea
    PLoS ONE 7:e41544. 2012
    ..The pronator drift test is widely used to detect mild arm weakness. We developed an application that runs on a handheld device to objectify the pronator drift test and investigated its feasibility in stroke patients...
  80. doi request reprint Therapeutic effect of magnesium lithospermate B on neointimal formation after balloon-induced vascular injury
    Kyu Yeon Hur
    Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, Republic of Korea
    Eur J Pharmacol 586:226-33. 2008
    ....
  81. pmc Stroke awareness decreases prehospital delay after acute ischemic stroke in Korea
    Young Seo Kim
    Department of Neurology, Seoul National University Hospital, Seoul, Republic of Korea
    BMC Neurol 11:2. 2011
    ..Our study aimed to investigate factors associated with prehospital delay after acute ischemic stroke in Korea...
  82. ncbi request reprint Lenticulostriate-medullary artery anastomoses in moyamoya disease
    Hyun Ji Cho
    Department of Neurology, Yonsei University College of Medicine, Shinchon dong, Seodaemoon Gu, Seoul, Korea
    Neurology 68:E21. 2007
  83. doi request reprint A mobile telemedicine system for remote consultation in cases of acute stroke
    Dong Keun Kim
    Center for Emergency Medical Informatics, Department of Medical Engineering, Yonsei University, College of Medicine, 134 Shinchon dong, Seodaemun Ku, Seoul, Korea
    J Telemed Telecare 15:102-7. 2009
    ..We conclude that specialists could generally conduct remote consultations for stroke patients either using a public mobile network or a wireless LAN...
  84. pmc Ultrastructural and temporal changes of the microvascular basement membrane and astrocyte interface following focal cerebral ischemia
    Il Kwon
    Department of Neurology, National Core Research Center for Nanomedical Technology, Yonsei University College of Medicine, Seoul, Korea
    J Neurosci Res 87:668-76. 2009
    ..Time courses of their alterations should be considered in the treatment targeted to the microvascular BM and its contact with astrocytes...
  85. ncbi request reprint Vestibular imbalance associated with a lesion in the nucleus prepositus hypoglossi area
    Sang Won Seo
    Department of Neurology, Brain Research Institute, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Shinchon Dong 134, Seodaemoon ku, Seoul 120 752, Korea
    Arch Neurol 61:1440-3. 2004
    ..Although the role of the human NPH is not well known, it may also function in postural balance, in view of its anatomic connections with the vestibular nuclei and vestibulocerebellum and of lesion studies in experimental animals...
  86. doi request reprint Patent foramen ovale: diagnosis with multidetector CT--comparison with transesophageal echocardiography
    Young Jin Kim
    Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University Health System, 250 Seongsanno, Seodaemun gu, Seoul, 120 752, Korea
    Radiology 250:61-7. 2009
    ..To evaluate the clinical feasibility and accuracy of 64-section multidetector computed tomography (CT) compared with transesophageal echocardiography (TEE) for diagnosis of a patent foramen ovale (PFO)...
  87. ncbi request reprint Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis
    Kyung Yul Lee
    Department of Neurology, Yongdong Severance Hospital, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, South Korea
    J Neurol Sci 220:73-8. 2004
    ..Inhibiting the MMPs may be an effective strategy for preventing or reducing the complications in tuberculous meningitis...
  88. ncbi request reprint Middle cerebral artery stenosis is a major clinical determinant in striatocapsular small, deep infarction
    Oh Young Bang
    Department of Neurology, College of Medicine, Ajou University, Woncheon dong San 5, Paldal Ku, Suwon, Kyungki do 442 749, South Korea
    Arch Neurol 59:259-63. 2002
    ..The significance of the stenotic lesions of the middle cerebral artery (MCA) in Asian patients with striatocapsular small, deep infarctions (SSDIs) remains undetermined...
  89. doi request reprint Intra-arterial thrombolytic therapy for hyperacute ischemic stroke caused by tandem occlusion
    Dong Joon Kim
    Department of Radiology, Research Institute of Radiological Science, Yongdong Severance Hospital, Seoul, South Korea
    Cerebrovasc Dis 26:184-9. 2008
    ..Although tandem occlusion is occasionally found during intra-arterial thrombolysis (IAT), as of yet no clear therapeutic strategy has been elucidated...