Research Topics
| Hyungdon YunSummaryAffiliation: Yeungnam University Country: Korea Publications
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Detail Information
Publications
Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminaseYoung Man Seo
School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, South Korea
Org Biomol Chem 10:2482-5. 2012..A whole cell reaction using a biphasic system converted 500 mM racemic homoalanine to 485 mM L-homoalanine (>99% ee)...
Biosynthetic substitution of tyrosine in green fluorescent protein with its surrogate fluorotyrosine in Escherichia coliNiraikulam Ayyadurai
School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
Biotechnol Lett 33:2201-7. 2011....
Kinetic resolution of aromatic β-amino acids by ω-transaminaseHan Seop Bea
School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, Korea
Chem Commun (Camb) 47:5894-6. 2011..Racemic aromatic β-amino acids have been kinetically resolved into (R)-β-amino acids with high enantiomeric excess (>99%) by a novel ω-TA with ca. 50% conversion...
Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobinYoung Man Seo
School of Biotechnology, Yeungnam University, Japan
Biosci Biotechnol Biochem 75:820-2. 2011..9 s⁻¹). rac-3-Flouroalanine (500 mM) was kinetically resolved into (R)-3-fluoroalanine with high enatiomeric excess (>99%) by VHb-DAAO with about 52% conversion...
Crystallization and preliminary X-ray crystallographic studies of β-transaminase from Mesorhizobium sp. strain LUKBokyung Kim
School of Biotechnology, Yeungnam University, Gyeongsan, Republic of Korea
Acta Crystallogr Sect F Struct Biol Cryst Commun 67:231-3. 2011..X-ray diffraction data were collected to a resolution of 2.5 Å from a crystal that belonged to the orthorhombic space group C222(1), with unit-cell parameters a = 90.91, b = 192.17, c = 52.75 Å...
Asymmetric synthesis of (S)-alpha-methylbenzylamine by recombinant Escherichia coli co-expressing omega-transaminase and acetolactate synthaseHyungdon Yun
School of Biotechnology, Yeungnam University, Gyeongbuk, Korea
Biosci Biotechnol Biochem 72:3030-3. 2008..5-fold, and the inhibitory (S)-alpha-MBA produced in the omega-transaminase reaction solution (pH 8.0) moved into the extraction solution (pH 3.0) via an organic solvent...
A facile and efficient method for the incorporation of multiple unnatural amino acids into a single proteinNiraikulam Ayyadurai
School of Biotechnology, Yeungnam University, South Korea
Chem Commun (Camb) 47:3430-2. 2011..This single protein exhibited two different novel functionalities acquired from the genetically incorporated unnatural amino acids, which is an interesting and not an inherent property of the protein...
Bioconjugation of L-3,4-dihydroxyphenylalanine containing protein with a polysaccharideNiraikulam Ayyadurai
School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
Bioconjug Chem 22:551-5. 2011..This novel approach holds great promise for widespread use to prepare protein conjugates and synthetic biology applications...
Enzymatic synthesis of L-tert-leucine with branched chain aminotransferaseYoung Man Seo
School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712 749, Korea
J Microbiol Biotechnol 21:1049-52. 2011..In the BCAT/ AspAT/PDC coupling reaction, 89.2 mM L-tert-leucine (ee >99%) was asymmetrically synthesized from 100 mM trimethylpyruvate...
