Hyungdon Yun

Summary

Affiliation: Yeungnam University
Country: Korea

Publications

  1. pmc Engineering of daidzein 3'-hydroxylase P450 enzyme into catalytically self-sufficient cytochrome P450
    Kwon Young Choi
    School of Chemical and Biological Engineering, Institute of Bioengineering, Seoul National University, Seoul, South Korea
    Microb Cell Fact 11:81. 2012
  2. doi request reprint One-pot one-step deracemization of amines using ω-transaminases
    Giyoung Shin
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea
    Chem Commun (Camb) 49:8629-31. 2013
  3. doi request reprint Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminase
    Young Man Seo
    School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, South Korea
    Org Biomol Chem 10:2482-5. 2012
  4. doi request reprint Biosynthetic substitution of tyrosine in green fluorescent protein with its surrogate fluorotyrosine in Escherichia coli
    Niraikulam Ayyadurai
    School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
    Biotechnol Lett 33:2201-7. 2011
  5. pmc Crystallization and preliminary X-ray crystallographic studies of β-transaminase from Mesorhizobium sp. strain LUK
    Bokyung Kim
    School of Biotechnology, Yeungnam University, Gyeongsan, Republic of Korea
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:231-3. 2011
  6. doi request reprint An in silico approach to evaluate the polyspecificity of methionyl-tRNA synthetases
    Saravanan Prabhu Nadarajan
    School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
    J Mol Graph Model 39:79-86. 2013
  7. doi request reprint Kinetic resolution of aromatic β-amino acids by ω-transaminase
    Han Seop Bea
    School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, Korea
    Chem Commun (Camb) 47:5894-6. 2011
  8. ncbi request reprint Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobin
    Young Man Seo
    School of Biotechnology, Yeungnam University, Japan
    Biosci Biotechnol Biochem 75:820-2. 2011
  9. doi request reprint Enhancing the biophysical properties of mRFP1 through incorporation of fluoroproline
    Kanagavel Deepankumar
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea
    Biochem Biophys Res Commun 440:509-14. 2013
  10. ncbi request reprint Enzymatic synthesis of L-tert-leucine with branched chain aminotransferase
    Young Man Seo
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712 749, Korea
    J Microbiol Biotechnol 21:1049-52. 2011

Collaborators

  • Byung Gee Kim
  • Sam Mathew
  • Yong Ho Khang
  • Hyung Joon Cha
  • Sun Gu Lee
  • Niraikulam Ayyadurai
  • Kanagavel Deepankumar
  • Young Man Seo
  • Saravanan Prabhu Nadarajan
  • Han Seop Bea
  • Nadarajan Saravanan Prabhu
  • Giyoung Shin
  • Kwon Young Choi
  • Minsu Shon
  • Byeo Ri An
  • Da Hye Jung
  • Changmin Sung
  • Hyung Yeon Park
  • Eunok Jung
  • Bishnu Prasad Pandey
  • Nataraj Chitrapriya
  • Aran Kim
  • Eunjung Song
  • Nediljko Budisa
  • Nahum Lee
  • Yoon Jung Jang
  • Hye Jeong Park
  • Seog K Kim
  • Nagasundarapandian Soundrarajan

Detail Information

Publications13

  1. pmc Engineering of daidzein 3'-hydroxylase P450 enzyme into catalytically self-sufficient cytochrome P450
    Kwon Young Choi
    School of Chemical and Biological Engineering, Institute of Bioengineering, Seoul National University, Seoul, South Korea
    Microb Cell Fact 11:81. 2012
    ..Finally, a recombinant Streptomyces avermitilis host for the expression of 3'-ASDH and production of the hydroxylated product was developed. The conversion that was attained (34.6%) was 5.2-fold higher than that of the wild-type...
  2. doi request reprint One-pot one-step deracemization of amines using ω-transaminases
    Giyoung Shin
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea
    Chem Commun (Camb) 49:8629-31. 2013
    ..Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion. ..
  3. doi request reprint Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminase
    Young Man Seo
    School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, South Korea
    Org Biomol Chem 10:2482-5. 2012
    ..A whole cell reaction using a biphasic system converted 500 mM racemic homoalanine to 485 mM L-homoalanine (>99% ee)...
  4. doi request reprint Biosynthetic substitution of tyrosine in green fluorescent protein with its surrogate fluorotyrosine in Escherichia coli
    Niraikulam Ayyadurai
    School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
    Biotechnol Lett 33:2201-7. 2011
    ....
  5. pmc Crystallization and preliminary X-ray crystallographic studies of β-transaminase from Mesorhizobium sp. strain LUK
    Bokyung Kim
    School of Biotechnology, Yeungnam University, Gyeongsan, Republic of Korea
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:231-3. 2011
    ..X-ray diffraction data were collected to a resolution of 2.5 Å from a crystal that belonged to the orthorhombic space group C222(1), with unit-cell parameters a = 90.91, b = 192.17, c = 52.75 Å...
  6. doi request reprint An in silico approach to evaluate the polyspecificity of methionyl-tRNA synthetases
    Saravanan Prabhu Nadarajan
    School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
    J Mol Graph Model 39:79-86. 2013
    ..Given the close similarity in the active site residues of these systems, we evaluated the polyspecificity of MetRSs...
  7. doi request reprint Kinetic resolution of aromatic β-amino acids by ω-transaminase
    Han Seop Bea
    School of Biotechnology, Yeungnam University, Gyeongbuk, 712 749, Korea
    Chem Commun (Camb) 47:5894-6. 2011
    ..Racemic aromatic β-amino acids have been kinetically resolved into (R)-β-amino acids with high enantiomeric excess (>99%) by a novel ω-TA with ca. 50% conversion...
  8. ncbi request reprint Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobin
    Young Man Seo
    School of Biotechnology, Yeungnam University, Japan
    Biosci Biotechnol Biochem 75:820-2. 2011
    ..9 s⁻¹). rac-3-Flouroalanine (500 mM) was kinetically resolved into (R)-3-fluoroalanine with high enatiomeric excess (>99%) by VHb-DAAO with about 52% conversion...
  9. doi request reprint Enhancing the biophysical properties of mRFP1 through incorporation of fluoroproline
    Kanagavel Deepankumar
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea
    Biochem Biophys Res Commun 440:509-14. 2013
    ..Our study showed that a successful enhancement in the biophysical property of mRFP1-P63A[(4R)-FP] using non-canonical amino acid mutagenesis after mutating non-permissive site Pro63 into Ala. ..
  10. ncbi request reprint Enzymatic synthesis of L-tert-leucine with branched chain aminotransferase
    Young Man Seo
    School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 712 749, Korea
    J Microbiol Biotechnol 21:1049-52. 2011
    ..In the BCAT/ AspAT/PDC coupling reaction, 89.2 mM L-tert-leucine (ee >99%) was asymmetrically synthesized from 100 mM trimethylpyruvate...
  11. doi request reprint Bioconjugation of L-3,4-dihydroxyphenylalanine containing protein with a polysaccharide
    Niraikulam Ayyadurai
    School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
    Bioconjug Chem 22:551-5. 2011
    ..This novel approach holds great promise for widespread use to prepare protein conjugates and synthetic biology applications...
  12. doi request reprint A facile and efficient method for the incorporation of multiple unnatural amino acids into a single protein
    Niraikulam Ayyadurai
    School of Biotechnology, Yeungnam University, South Korea
    Chem Commun (Camb) 47:3430-2. 2011
    ..This single protein exhibited two different novel functionalities acquired from the genetically incorporated unnatural amino acids, which is an interesting and not an inherent property of the protein...
  13. ncbi request reprint Asymmetric synthesis of (S)-alpha-methylbenzylamine by recombinant Escherichia coli co-expressing omega-transaminase and acetolactate synthase
    Hyungdon Yun
    School of Biotechnology, Yeungnam University, Gyeongbuk, Korea
    Biosci Biotechnol Biochem 72:3030-3. 2008
    ..5-fold, and the inhibitory (S)-alpha-MBA produced in the omega-transaminase reaction solution (pH 8.0) moved into the extraction solution (pH 3.0) via an organic solvent...