Research Topics
Genomes and Genes | Rina YuSummaryAffiliation: University of Ulsan Country: Korea Publications
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Publications
Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese miceRina Yu
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, Korea
Obesity (Silver Spring) 14:1353-62. 2006..To determine whether chemokines, which play a pivotal role in monocyte/macrophage trafficking, modulate macrophage infiltration into and activation in the adipose tissues...
Inflammatory components of adipose tissue as target for treatment of metabolic syndromeRina Yu
Department of Food Science and Nutrition, University of Ulsan, Ulsan, South Korea
Forum Nutr 61:95-103. 2009..In particular, we focus on the hypothesis that anti-inflammatory food factors/phytochemicals may be useful for inhibiting the initiation and development of obesity-induced inflammation and metabolic syndrome...- Involvement of leukotactin-1, a novel CC chemokine, in human atherosclerosisRina Yu
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, South Korea
Atherosclerosis 174:35-42. 2004..Lkn-1 stimulated endothelial cells to release ICAM-1, which is implicated in atherogenesis. Taken together, our data suggest that Lkn-1 plays an important role in the development of atherosclerosis... - Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophagesJi Hye Kang
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, South Korea
FEBS Lett 581:4389-96. 2007..Capsaicin may be a useful phytochemical for attenuating obesity-induced inflammation and obesity-related complications... - HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intoleranceHa Jung Kim
Department of Food Science and Nutrition, University of Ulsan, Ulsan, South Korea
FEBS Lett 585:2285-90. 2011..These findings indicate that HVEM may be a useful target for combating obesity-induced inflammatory responses and insulin resistance... - Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat dietJi Hye Kang
Department of Food Science and Nutrition, University of Ulsan, Ulsan, South Korea
Obesity (Silver Spring) 18:780-7. 2010..The effects of capsaicin in adipose tissue and liver are related to its dual action on PPARalpha and TRPV-1 expression/activation... - Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytesHae Mi Woo
Department of Food Science and Nutrition, University of Ulsan, Mugeo dong, Nam Ku, Ulsan, South Korea
Life Sci 80:926-31. 2007..These spice-derived components may have a potential to improve chronic inflammatory conditions in obesity... - Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic miceJi Hye Kang
Department of Food Science and Nutrition, University of Ulsan, Nam Ku, Ulsan, Republic of Korea
J Med Food 14:310-5. 2011..Capsaicin may be useful as a dietary factor for reducing obesity-related metabolic dysregulation... - Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2Ji Hye Kang
Department of Food Science and Nutrition, University of Ulsan, Mugeo dong, Nam Ku, Ulsan 680 749, Republic of Korea
Cancer Lett 261:84-92. 2008.... 
Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disordersChu Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Ulsan, South Korea
Diabetes 60:3159-68. 2011..Both 4-1BB and 4-1BBL have been shown to play an important role in the pathogenesis of various inflammatory diseases...- Chemokine and chemokine receptor gene expression in the mesenteric adipose tissue of KKAy miceHan Sam Lee
Department of Biological Sciences and Immunomodulation Research Center, University of Ulsan, Nam Ku Moogu Dong San29, Ulsan 680 749, Republic of Korea
Cytokine 46:160-5. 2009..To investigate chemokines and their receptors gene expression in the intra-abdominal adipose tissue of diabetic/obese mice... - The immune signaling molecule 4-1BB stimulation reduces adiposity, insulin resistance, and hepatosteatosis in obese miceChu Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Mugeo dong, Nam Ku, Ulsan 680 749, South Korea
Endocrinology 151:4725-35. 2010..Manipulation of 4-1BB may provide a unique immunological strategy against obesity and metabolic disorders... - Soybean saponins suppress the release of proinflammatory mediators by LPS-stimulated peritoneal macrophagesJi-Hye Kang
Department of Food Science and Nutrition, University of Ulsan, Mugeo-dong, Nam-ku, Ulsan 680-749, South Korea
Cancer Lett 230:219-27. 2005..The anti-inflammatory properties of soybean saponins may be useful for ameliorating inflammatory diseases as well as suppressing tumor progression... - Macrophage inflammatory protein-related protein-2, a novel CC chemokine, can regulate preadipocyte migration and adipocyte differentiationChu-Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Mugeo-dong, Nam-ku, Ulsan 680-749, South Korea
FEBS Lett 548:125-30. 2003..MRP-2 may be another adipocytokine, which can be involved in the adipocyte-related pathological process... - Absence of herpes virus entry mediator (HVEM) increases bone mass by attenuating receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesisWoon Ki Kim
Department of Biological Sciences, University of Ulsan, Ulsan 680 749, Korea
Endocrinology 153:4808-17. 2012..The higher bone mass in the femurs of HVEM-knockout mice could be, at least in part, due to attenuated osteoclastogenesis and bone resorption resulting from decreased receptor activator of nuclear factor-κB ligand signaling in the OC... - Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cellsChu-Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Ulsan
J Med Food 7:267-73. 2004..Capsaicin may have a beneficial effect for the treatment of colon cancer... - LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEMHong Min Kim
Department of Biological Science, University of Ulsan, Nam Ku, Ulsan, South Korea
FEBS Lett 585:579-84. 2011..These findings indicate that sLIGHT enhances adipose tissue inflammatory responses through its interaction with HVEM... - Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanismJun Young Park
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, Republic of Korea
FEBS Lett 572:266-70. 2004..7 cells, indicating that capsaicin acts like a ligand for PPARgamma. Our data demonstrate for the first time that the anti-inflammatory action of capsaicin may be mediated by PPARgamma activation in LPS-stimulated RAW 264.7 cells... - Alteration of a macrophages inflammatory protein-related protein-2 (MRP-2) response by high fat and cholesterol diet in miceRina Yu
Department of Food Science and Nutrition, University of Ulsan, Mugeo dong Nam ku, Ulsan 680 749, South Korea
Life Sci 70:2535-45. 2002..These results suggest that MRP-2 may be an important contributing factor in the development of atherosclerosis... - Potential involvement of CCL23 in atherosclerotic lesion formation/progression by the enhancement of chemotaxis, adhesion molecule expression, and MMP-2 release from monocytesChu Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Ulsan, 680 749, South Korea
Inflamm Res 60:889-95. 2011..In the present study, we investigated the role of CCL23 in the development of human atherosclerosis, which is characterized by an inflammatory disease... - Diet enriched with korean pine nut oil improves mitochondrial oxidative metabolism in skeletal muscle and brown adipose tissue in diet-induced obesityNgoc Hoan Le
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, South Korea
J Agric Food Chem 60:11935-41. 2012..Our findings suggest that PNO may have potential as a dietary supplement for counteracting obesity and metabolic dysregulation... - Saturated fatty acids enhance osteoclast survivalSo Ra Oh
Department of Biological Sciences BK21 Program, University of Ulsan, Ulsan 680 749, Korea
J Lipid Res 51:892-9. 2010..SFA caused the production of MIP-1alpha and led to activation of nuclear factor (NF)-kappaB in the OC. The absence of Toll-like receptor 4 (TLR4) or myeloid differentiation factor 88 (MyD88) abolished the survival effect of SFA on OC... - Osteoclastogenesis by bone marrow-derived macrophages is enhanced in obese miceTae Wook Kyung
Department of Biological Sciences BK21 Program and the Immunomodulation Research Center, University of Ulsan, Ulsan 680 749, Korea
J Nutr 139:502-6. 2009..Our results suggest that obesity is associated with bone loss via enhanced osteoclastogenesis due to reduced IL-10 production by the BMM from obese mice... - Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophagesChu-Sook Kim
Department of Food Science and Nutrition, University of Ulsan, Mugeo-dong, Nam-ku, Ulsan 680-749, South Korea
Cell Signal 15:299-306. 2003..Both capsaicin and capsazepine may be a promising drug candidates for ameliorating inflammatory diseases and cancer... - Administration of 6-gingerol greatly enhances the number of tumor-infiltrating lymphocytes in murine tumorsSeong A Ju
Biomedical Research Center, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea
Int J Cancer 130:2618-28. 2012..Our results strongly suggest that 6-gingerol can be used in tumor immunotherapy to increase the number of TILs... - Chemokine Lkn-1/CCL15 enhances matrix metalloproteinase-9 release from human macrophages and macrophage-derived foam cellsSang Hee Kwon
Department of Food Science and Nutrition, University of Ulsan, Ulsan 680 749, Korea
Nutr Res Pract 2:134-7. 2008..Our data suggest that the action of Lkn-1/CCL15 on macrophages and foam cells to release MMP-9 may contribute to plaque destabilization in the progression of atherosclerosis... - Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6Hye Soon Park
Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, South Korea
Diabetes Res Clin Pract 69:29-35. 2005..To investigate the relationship between serum concentrations of the cytokines C-reactive protein (CRP), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6, and obesity and visceral adiposity... - Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophagesShizuka Hirai
Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
Life Sci 81:1272-9. 2007..Naringenin chalcone may be useful for ameliorating the inflammatory changes in obese adipose tissue... - The role of adipocytokines in adipocyte-related pathological processesByung-S Youn
KOMED Institute for Life Science, Korea University, Seoul, Korea
Drug News Perspect 17:293-8. 2004..In this review, we summarize recent advances in understanding the roles of adiponectin and resistin in the causation of metabolic diseases and consider the prospects for treating metabolic disorders by targeting these two adipocytokines... - Abietic acid activates peroxisome proliferator-activated receptor-gamma (PPARgamma) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolismNobuyuki Takahashi
Laboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan
FEBS Lett 550:190-4. 2003..The present work suggests a novel possibility that abietic acid, a naturally occurring compound, can be used not only for anti-inflammation but also for regulating lipid metabolism and atherosclerosis... - Dietary regulation of nuclear receptors in obesity-related metabolic syndromeTeruo Kawada
Kyoto University, Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Uji, Kyoto 611 0011, Japan
Asia Pac J Clin Nutr 17:126-30. 2008..These findings indicate that dietary factor acts as an agonist of PPARs and is a valuable medical and food component for the gradual improvement of metabolic syndrome...