Dong Myung Shin
Affiliation: University of Ulsan
Jue M, Lee S, Paulson B, Namgoong J, Yu H, Kim G, et al
. Optimization of ZnO Nanorod-Based Surface Enhanced Raman Scattering Substrates for Bio-Applications. Nanomaterials (Basel). 2019;9: pubmed publisher
..These results establish design guidelines for future use of Au-ZnO nanorods in the study and early diagnosis of inflammatory diseases. ..
Lee S, Namgoong J, Yu H, Jue M, Kim G, Jeon S, et al
. Diagnosis in a Preclinical Model of Bladder Pain Syndrome Using a Au/ZnO Nanorod-based SERS Substrate. Nanomaterials (Basel). 2019;9: pubmed publisher
..The PCA results are plotted in 2D and 3D. The Raman signals and statistical analyses obtained from the nano-sized biomarkers of intractable inflammatory diseases demonstrate the possibility of an early diagnosis. ..
Choi D, Han J, Shin J, Ryu C, Yu H, Kim A, et al
. Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion. Sci Rep. 2018;8:9782 pubmed publisher
..Downregulation of WNT11 results in fibrotic changes of bladder epithelial cells and is associated with the pathogenesis and differential diagnosis of NHIC. Decreased expression of WNT11 is a potential biomarker for predicting NHIC. ..
Kim Y, Jin H, Heo J, Ju H, Lee H, Kim S, et al
. Small hypoxia-primed mesenchymal stem cells attenuate graft-versus-host disease. Leukemia. 2018;32:2672-2684 pubmed publisher
..Collectively, our findings suggest that SHC-MSCs can improve the clinical treatment of allogeneic conflicts, including GVHD. ..
Lim J, Kim Y, Heo J, Kim K, Lee S, Lee S, et al
. Priming with ceramide-1 phosphate promotes the therapeutic effect of mesenchymal stem/stromal cells on pulmonary artery hypertension. Biochem Biophys Res Commun. 2016;473:35-41 pubmed publisher
Jeong E, Yoon J, Lim J, Shin J, Cho A, Heo J, et al
. Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function. Stem Cell Reports. 2018;10:600-614 pubmed publisher
..Our results indicate that high glutathione levels are required for maintaining SC functions, and monitoring glutathione dynamics and heterogeneity can advance our understanding of the cellular responses to oxidative stress. ..
Shin D, Liu R, Wu W, Waigel S, Zacharias W, Ratajczak M, et al
. Global gene expression analysis of very small embryonic-like stem cells reveals that the Ezh2-dependent bivalent domain mechanism contributes to their pluripotent state. Stem Cells Dev. 2012;21:1639-52 pubmed publisher
Heo J, Lim J, Lee S, Jeong J, Kang H, Kim Y, et al
. Sirt1 Regulates DNA Methylation and Differentiation Potential of Embryonic Stem Cells by Antagonizing Dnmt3l. Cell Rep. 2017;18:1930-1945 pubmed publisher
..This study sheds light on mechanisms that restrain DNA methylation of developmentally vital genes operating in ESCs. ..
Kim A, Yu H, Lim J, Ryu C, Kim Y, Heo J, et al
. Improved efficacy and in vivo cellular properties of human embryonic stem cell derivative in a preclinical model of bladder pain syndrome. Sci Rep. 2017;7:8872 pubmed publisher
..The present study provides the first evidence for improved therapeutic efficacy, long-term safety, and in vivo distribution and cellular properties of hESC derivatives in preclinical models of IC/BPS. ..