In Ki Kim
Affiliation: University of Ulsan
Kim J, Kim Y, Bang S, Yoo H, Kim I, Chang S, et al
. L-765,314 Suppresses Melanin Synthesis by Regulating Tyrosinase Activity. Molecules. 2019;24: pubmed publisher
Thida M, Kim D, Tran T, Pham M, Lee H, Kim I, et al
. Gambogic acid induces apoptotic cell death in T98G glioma cells. Bioorg Med Chem Lett. 2016;26:1097-1101 pubmed publisher
..Furthermore, GA induced reactive oxygen species (ROS) generation in T98G cells. Our results indicate that GA increases Bax- and AIF-associated apoptotic signaling in glioblastoma cells. ..
Hong M, Kim H, Kim I. Ribosomal protein L19 overexpression activates the unfolded protein response and sensitizes MCF7 breast cancer cells to endoplasmic reticulum stress-induced cell death. Biochem Biophys Res Commun. 2014;450:673-8 pubmed publisher
..Our findings suggest that upregulation of RPL19 induces ER stress, resulting in increased sensitivity to ER stress and enhanced cell death in MCF7 breast cancer cells. ..
Lee K, Yang S, Park S, Choi Y, Shin H, Pak J, et al
. Depletion of the cereblon gene activates the unfolded protein response and protects cells from ER stress-induced cell death. Biochem Biophys Res Commun. 2015;458:34-9 pubmed publisher
..We propose that CRBN plays a role in cellular stress signaling, including the unfolded protein response, by controlling the activity of AMPK. ..
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
..We suggest from these data that AMC-01 and its derivative compounds can be used as chemical probes in future studies of the role of eIF2-Î± in protein synthesis-related cell physiology. ..
Kim N, Choi J, Park H, Kim I, Kim H. Amphotericin B, an Anti-Fungal Medication, Directly Increases the Cytotoxicity of NK Cells. Int J Mol Sci. 2017;18: pubmed publisher
..The results of the present study indicate that AMP-B could serve a dual function as an anti-fungal and immunomodulatory drug. ..