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Genomes and Genes | D S KimSummaryAffiliation: University of Ulsan Country: Korea Publications
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Publications
Acute exacerbation of idiopathic pulmonary fibrosisDong Soon Kim
Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea
Clin Chest Med 33:59-68. 2012..In 2007 Collard and colleagues created a Consensus Perspective, which proposed consensus definition and standard diagnostic criteria. This review primarily discusses studies performed after this Consensus Perspective...
A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing modeMi Hyun Ahn
Div of Allergy and Respiratory Medicine, Dept of Internal Medicine, Soonchunhyang Univ, Bucheon Hospital, 1174 Jung dong, Wonmi gu, Bucheon 420 020, Korea
Respir Res 12:73. 2011..The IL-8 protein and mRNA expression are increased in the lung with IPF. We evaluated the effect of single nucleotide polymorphisms (SNPs) of the IL-8 gene on the risk of IPF...
Diagnostic utility of the soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid from patients with bilateral lung infiltratesJin Won Huh
Department of Pulmonary and Critical Care Medicine, Ilsan Paik Hospital, Inje University, 2240, Daehwa dong, Ilsanseo gu, Goyang si, Gyeonggi Do, 411 706, Korea
Crit Care 12:R6. 2008..Here we evaluate the diagnostic role of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in bronchoalveolar lavage (BAL) specimens from patients with bilateral lung infiltrates...
Interstitial lung disease in rheumatoid arthritis: recent advancesDong Soon Kim
Asan Medical Center, University of Ulsan, Seoul, Republic of Korea
Curr Opin Pulm Med 12:346-53. 2006..Recent papers on rheumatoid arthritis suggest that this is not the same in all collagen diseases, and this paper will review previous data and discuss recent papers...
Classification and natural history of the idiopathic interstitial pneumoniasDong Soon Kim
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan, 388 1 Poongnap dong, Songpa Ku, Seoul, Korea, 138 736
Proc Am Thorac Soc 3:285-92. 2006..However, there is still confusion and controversy over the relationship between idiopathic pulmonary fibrosis and fibrotic nonspecific interstitial pneumonia...
Prevalence of chronic obstructive pulmonary disease in Korea: a population-based spirometry surveyDong Soon Kim
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, 388 1, Poongnap dong, Songpa Gu, Seoul, South Korea
Am J Respir Crit Care Med 172:842-7. 2005..Although chronic obstructive pulmonary disease is a leading cause of mortality and morbidity worldwide, there are only limited data on its prevalence, especially in Asia...
Acute exacerbation of idiopathic pulmonary fibrosis: incidence, risk factors and outcomeJ W Song
Dept of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul, South Korea
Eur Respir J 37:356-63. 2011..1- and 3-yr incidences of acute exacerbation were 14.2 and 20.7%, respectively. Never having smoked and low FVC were risk factors. Acute exacerbation had a serious impact on the overall survival of the patients with IPF...
Physiology is a stronger predictor of survival than pathology in fibrotic interstitial pneumoniaYangjin Jegal
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap Dong Songpa Ku, Seoul 138 736, South Korea
Am J Respir Crit Care Med 171:639-44. 2005..Our data confirmed the importance of physiological parameters including short-term change in FVC. However, at the time of diagnosis, histopathology was important for the prediction of prognosis and future change in lung function...
The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumoniaDong Soon Kim
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
Sarcoidosis Vasc Diffuse Lung Dis 19:121-7. 2002....
Acute exacerbation of idiopathic pulmonary fibrosis: frequency and clinical featuresD S Kim
Dept of Pulmonary and Critical Care Medicine, Asan Medical Center, Ulsan University, Poongnap dong, Songpa Ku, Seoul, Korea
Eur Respir J 27:143-50. 2006..The findings of this study demonstrate that acute exacerbation of idiopathic pulmonary fibrosis is rather common and this exacerbation is likely to have a spectrum of severity...
Heat shock response decreases endotoxin-induced acute lung injury in ratsY Koh
Department of Internal Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
Respirology 4:325-30. 1999..Transient whole-body hyperthermia was reported to reduce lung damage in a rat with intra-abdominal sepsis produced by caecal perforation...
Comparison of the response to the prone position between pulmonary and extrapulmonary acute respiratory distress syndromeC M Lim
Division of Pulmonary and Critical Care Medicine, Asan Medical Centre, College of Medicine, University of Ulsan, Seoul 138 600, Korea
Intensive Care Med 27:477-85. 2001..To determine whether the response to the prone position differs between acute respiratory distress syndrome (ARDS) resulting from a pulmonary cause (ARDSp) and that from an extrapulmonary cause (ARD-Sexp)...
Combined use of QuantiFERON-TB Gold assay and chest computed tomography in a tuberculosis outbreakW J Lew
The Korean Institute of Tuberculosis, Seoul, Korea
Int J Tuberc Lung Dis 13:633-9. 2009....
Value of ICAM-1 expression and soluble ICAM-1 level as a marker of activity in sarcoidosisD S Kim
Department of Internal Medicine, Asan Medical Center, Ulsan University, Seoul, Korea
Chest 115:1059-65. 1999..Adhesion molecules are required for the migration of inflammatory cells; thus, they may be markers of activity in sarcoidosis...
Pulmonary tuberculosis with acute respiratory failureY J Kim
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Eur Respir J 32:1625-30. 2008..The present study reveals the need for randomised controlled trials to clarify the role of corticosteroids as adjunctive therapy in the management of tuberculous pneumonia with acute respiratory failure...
Lung cancer in patients with idiopathic pulmonary fibrosisJ Park
Dept of Pulmonary Medicine, Asan Medical Center, School of Medicine, University of Ulsan, Seoul, Korea
Eur Respir J 17:1216-9. 2001..These findings suggest that in combined lung cancer and idiopathic pulmonary fibrosis patients, the features of the lung cancer are similar to the total lung cancer population...
The roles of fractalkine/CX3CR1 system in neuronal death following pilocarpine-induced status epilepticusS I Yeo
Department of Anatomy and Neurobiology, College of Medicine, Hallym University, Chunchon, Kangwon Do 200 702, South Korea
J Neuroimmunol 234:93-102. 2011..These findings suggest that fractalkine/CX3CR1 system may play an important role in SE-induced neuronal damages via neuron-microglial interactions...
The prognosis of respiratory failure in patients with tuberculous destroyed lungJ H Park
Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
Int J Tuberc Lung Dis 5:963-7. 2001..A higher PaCO2 measurement could indicate a better survival rate in this group of patients...
The value of interleukin-12 as an activity marker of pulmonary sarcoidosisD S Kim
Department of Pulmonary Medicine, Asan Medical Center, University of Ulsan, School of Medicine, Seoul, Korea
Sarcoidosis Vasc Diffuse Lung Dis 17:271-6. 2000..IL-12 is a major cytokine inducing Th1 differentiation of naive T cells. This study was performed to test whether IL-12 can be a marker for disease activity and possibly a prognosis in sarcoidosis...
Closing volume influences the postural effect on oxygenation in unilateral lung diseaseK H Choe
Pulmonary and Critical Care Division, Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea
Am J Respir Crit Care Med 161:1957-62. 2000..597, p = 0.015). This study has shown that closing volume, as well as posture, might be involved in determining oxygenation in lateral recumbency in patients with unilateral lung disease...
Mechanistic scheme and effect of "extended sigh" as a recruitment maneuver in patients with acute respiratory distress syndrome: a preliminary studyC M Lim
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Crit Care Med 29:1255-60. 2001..To devise a new form of sigh ("extended sigh") capable of providing a sufficient recruiting pressure x time, and to test it as a recruitment maneuver in patients with acute respiratory distress syndrome...
Clinical course and lung function change of idiopathic nonspecific interstitial pneumoniaI N Park
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Pungnap 2dong, Songpa Gu, Seoul 138 736, Korea
Eur Respir J 33:68-76. 2009..Some patients developed collagen vascular diseases at a later date...
Cigarette smoke extract induces endothelin-1 via protein kinase C in pulmonary artery endothelial cellsS D Lee
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, College of Medicine Ulsan University, Songpa Gu, 138 736 Seoul, Korea
Am J Physiol Lung Cell Mol Physiol 281:L403-11. 2001..Thus our data suggest that CSE stimulates ET-1 gene expression via PKC in PAECs. CSE and platelets showed a synergistic effect on ET-1 gene expression, possibly through the activation of platelets by CSE...
Effects of heat pretreatment on histopathology, cytokine production, and surfactant in endotoxin-induced acute lung injuryY Koh
Department of Internal Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
Inflammation 25:187-96. 2001..These observations suggest that IL-10 might play a role in decreasing LPS-induced acute lung injury after heat-pretreatment...
Transforming growth factor-beta1 induces endothelin-1 in a bovine pulmonary artery endothelial cell line and rat lungs via cAMPS D Lee
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, College of Medicine Ulsan University, 388 1 Poongnab dong, Songpa Gu, Seoul, Korea
Pulm Pharmacol Ther 13:257-65. 2000..Thus our data suggest that TGF-beta1 stimulates ET-1 gene expression in BPAECs and in rat lungs via a cAMP dependent mechanism...
Distinguishing tuberculosis from Mycobacterium avium complex disease using an interferon-gamma release assayS W Ra
Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
Int J Tuberc Lung Dis 15:635-40. 2011..Although the QuantiFERON-TB (QFT) test, the first-generation QFT-G test, employs a non-specific PPD antigen, avium sensitin is also used as a stimulating antigen...
Establishing a surveillance network for severe lower respiratory tract infections in Korean infants and young childrenJ K Chun
Department of Pediatrics, Yonsei University College of Medicine, Severance Children s Hospital, 250 Seongsanno, Seodaemun gu, Seoul, 120 752, South Korea
Eur J Clin Microbiol Infect Dis 28:841-4. 2009..Using our methods to detect viral causes seemed to be acceptable for the national surveillance of severe acute respiratory infections in infants and children...
Hypothermia attenuates vascular manifestations of ventilator-induced lung injury in ratsC M Lim
Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 138 600
Lung 181:23-34. 2003..In conclusion, hypothermia in rats attenuated the degrees of vascular manifestations and alveolar epithelial injuries induced by injurious ventilation, and preserved the mechanical properties of the lung...
GenoType® MTBDRplus assay detection of drug-resistant tuberculosis in routine practice in KoreaJ Lyu
Department of Pulmonary and Critical Care Medicine, Inje University Haeundae Paik Hospital, Haeundae gu, Busan, South Korea
Int J Tuberc Lung Dis 17:120-4. 2013..Korea is an intermediate-burden country with high rates of tuberculosis (TB) drug resistance...
Potential roles of D-serine and serine racemase in experimental temporal lobe epilepsyH J Ryu
Department of Anatomy and Neurobiology, College of Medicine, Hallym University, Chunchon, Kangwon Do, Republic of Korea
J Neurosci Res 88:2469-82. 2010..Furthermore, serine racemase may be involved in migration and differentiation of immature astrocytes, which is relevant to reactive astrogliosis...
Acute exacerbation of interstitial pneumonia other than idiopathic pulmonary fibrosisI Nae Park
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Pungnap 2dong, Songpa Gu, Seoul 138 736, Korea
Chest 132:214-20. 2007..However, clinical data on AE in non-IPF interstitial pneumonia are sparse. This study was performed to find the frequency, clinical features, and outcome of AE in non-IPF interstitial pneumonia...
Overexpression of HSP70 prevents ultraviolet B-induced apoptosis of a human melanoma cell lineK C Park
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
Arch Dermatol Res 292:482-7. 2000..These results suggest that UVB-induced apoptosis of melanoma cells is accompanied by caspase-3 activation and PARP cleavage, which can be prevented by an overexpression of HSP70...
Growth related secretion and production of GM-CSF by epithelial cell lineK C Park
Department of Dermatology and Artificial Organ Laboratory, Clinical Research Institute, Seoul National University College of Medicine, Yungon dong 28, Chongno Gu, 110 744, Seoul, South Korea
J Dermatol Sci 25:53-8. 2001..Thus, it might be said that GM-CSF produced by proliferating keratinocytes possibly contributes to wound healing and melanogenesis at the site of injury...
Pathogenic role of endothelin 1 in hemodynamic dysfunction in experimental acute pulmonary thromboembolismJ H Lee
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, Seoul, Korea
Am J Respir Crit Care Med 164:1282-7. 2001..These findings suggest that ET-1 partially contributes to hemodynamic derangements of APE, and that ET(A) receptor antagonists might constitute a useful therapeutic tool for APE...
Nitric oxide and molsidomine in the management of pulmonary hypertension in Takayasu's arteritisS D Lee
Department of Internal Medicine, Asan Medical Center, College of Medicine, Ulsan University, Seoul, Korea
Chest 119:302-7. 2001..With molsidomine, 4 mg tid, dyspnea, exercise capacity, and hemodynamic parameters were improved. These favorable responses have lasted during the 3-month follow-up period in all patients...
Combined use of a TST and the T-SPOT®.TB assay for latent tuberculosis infection diagnosis before anti-TNF-α treatmentY J Jung
Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Int J Tuberc Lung Dis 16:1300-6. 2012..However, the tuberculin skin test (TST) has limitations, and the role of interferon-gamma release assays has not yet been determined...
Cerebral metabolic abnormalities in COPD patients detected by localized proton magnetic resonance spectroscopyT S Shim
Division of Pulmonary and Critical Care Medicine, Han Yang University Hospital, Seoul, Korea
Chest 120:1506-13. 2001....
Sarcoidosis in Korea: report of the Second Nationwide SurveyD S Kim
Korean Academy of Tuberculosis and Respiratory Diseases, Department of Pulmonary Medicine, Asan Medical Center, University of Ulsan, School of Medicine, Seoul, Korea
Sarcoidosis Vasc Diffuse Lung Dis 18:176-80. 2001..To investigate whether sarcoidosis is continuously increasing in Korea and verify the clinical pattern, the second nationwide survey was performed...
Non-tuberculous mycobacterial diseases presenting as solitary pulmonary nodulesJ Lim
Division of Pulmonary and Critical Care Medicine, Gangneung Asan Hospital, Gangneung, Korea
Int J Tuberc Lung Dis 14:1635-40. 2010..South Korea, 2005-2007...
Human rotavirus genotypes in hospitalized children, South Korea, April 2005 to March 2007S Y Lee
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Incheon St Mary s Hospital, Incheon, South Korea
Vaccine 27:F97-101. 2009..This large-scale surveillance study provides important insights into rotavirus genotype distribution and pattern changes in South Korea...
Maternal and fetal survival following surgery and chemotherapy of endodermal sinus tumor of the ovary during pregnancy: a case reportD S Kim
Department of Obstetrics and Gynecology, School of Medicine, Hanyang University, Seoul, Korea
Obstet Gynecol 73:503-7. 1989..We believe this is the first reported case of maternal survival past 2 years and the earliest chemotherapy done in the early second trimester of pregnancy without resulting in fetal abnormalities...
Impact of short-term exposure to fluoroquinolones on ofloxacin resistance in HIV-negative patients with tuberculosisI N Park
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Int J Tuberc Lung Dis 11:319-24. 2007..Seoul, Korea, a country with an intermediate tuberculosis (TB) burden and low prevalence of human immunodeficiency virus (HIV) infection...
Phase II study of radiotherapy with three-dimensional conformal boost concurrent with paclitaxel and cisplatin for Stage IIIB non-small-cell lung cancerYoung Seok Kim
Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, South Korea
Int J Radiat Oncol Biol Phys 62:76-81. 2005..Further investigations are needed to improve the local control...
Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis?Jin Won Huh
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, 388 1, Poongnap dong, Songpa Gu, Seoul, Korea
Chest 133:1101-6. 2008..The aim of this study was to investigate the role of MMP-7 in IIP by comparing its expression in usual interstitial pneumonia (UIP) and cryptogenic organizing pneumonia (COP)...
Naked DNA expressing two isoforms of hepatocyte growth factor induces collateral artery augmentation in a rabbit model of limb ischemiaW B Pyun
Department of Cardiology, Medical College of Ewha Womans University, Mokdong Hospital, Seoul, Korea
Gene Ther 17:1442-52. 2010..These results showed that transfer of the genomic-cDNA hybrid of the HGF gene could be used as a potential therapeutic approach to human vascular diseases...
UVB-induced GM-CSF production is suppressed by dexamethasone in HaCaT cellsD S Kim
Department of Dermatology, Seoul National University, College of Medicine, Korea
Photodermatol Photoimmunol Photomed 17:121-5. 2001..CONCLUSION: Results showed that dexamethasone suppressed basal release and UVB-induced production of GM-CSF by keratinocytes...
Significance of high-risk human papillomavirus detection by polymerase chain reaction in primary cervical cancer screeningY L Oh
Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, Korea
Cytopathology 12:75-83. 2001..The combination of Pap smear and high-risk HPV testing by PCR might reduce unnecessary colposcopy-guided biopsy of women with cytological diagnosis of ASCUS...
Expression of the HMGI(Y) gene in human colorectal cancerD H Kim
Department of Pathology, Hallym University, Seoul, Korea
Int J Cancer 84:376-80. 1999..Our results indicate that the HMGI(Y) expression may occur at an early stage of carcinogenesis and correlate with cell proliferation. Int. J. Cancer (Pred. Oncol.), 84:376-380, 1999...
Incidence of tuberculosis among health care workers at a private university hospital in South KoreaK W Jo
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Centre, Seoul, Korea
Int J Tuberc Lung Dis 12:436-40. 2008..A private university hospital in South Korea...
Aberrant expression of cyclin D1 is associated with poor prognosis in early stage cervical cancer of the uterusD S Bae
Department of Obstetrics and Gynecology, Sungkyunkwan University School of Medicine, Seoul, 135-710, Korea
Gynecol Oncol 81:341-7. 2001..We conclude that immunohistochemical assessment of cyclin D1 can be a useful molecular marker for predicting prognosis in early stage cervical cancer of the uterus...
Prevalence and patterns of anti-nuclear antibodies in Korean children with juvenile idiopathic arthritis according to ILAR criteriaJ I Shin
Department of Paediatrics, Yonsei University College of Medicine, Severance Children s Hospital, Seoul, Korea
Scand J Rheumatol 37:348-51. 2008..To investigate the prevalence and patterns of anti-nuclear antibodies (ANA) in different subtypes of juvenile idiopathic arthritis (JIA) according to the International League of Associations for Rheumatology (ILAR) criteria...
Suitable whole blood levels 2 hours after neoral in liver transplant patients: experiences at a single centerK H Kim
Division of HBP Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Transplant Proc 38:2971-3. 2006..Owing to concerns about drug toxicity due to excessive immunosuppression, C2 adjustments to target blood levels may represent an advance. The present study measured C2 and levels to determine which correlated more closely with AUC(0-4)...
Histopathologic pattern and clinical features of rheumatoid arthritis-associated interstitial lung diseaseHyun-Kyung Lee
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan, College of Medicine, 388-1, Poongnap-dong, Songpa-ku, Seoul, Korea 138-73
Chest 127:2019-27. 2005..2 years and 3.7 years, respectively. CONCLUSIONS: The histopathologic type of RA-ILD was diverse; in our study population, the UIP pattern seemed to be more prevalent than the NSIP pattern...
Hypothermia inhibits cytokine release of alveolar macrophage and activation of nuclear factor kappaB in endotoxemic lungChae Man Lim
POB 145 Songpa, 138 600 Seoul, Korea
Intensive Care Med 30:1638-44. 2004....
Weekly low dose paclitaxel and cisplatin as first-line chemotherapy for advanced non-small cell lung cancerSang We Kim
Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap Dong Songpa Ku, Seoul 138 736, South Korea
Lung Cancer 41:221-6. 2003..This study indicates that weekly low dose chemotherapy using paclitaxel and cisplatin could be given safely to the patients with NSCLC and showed a promising response rate...
Phase II study of three-dimensional conformal radiotherapy and concurrent mitomycin-C, vinblastine, and cisplatin chemotherapy for Stage III locally advanced, unresectable, non-small-cell lung cancerSang-Wook Lee
Department of Radiation Oncology, Asan Medical Center, University of Ulsan Medical College, Songpa-ku, Seoul, South Korea
Int J Radiat Oncol Biol Phys 56:996-1004. 2003..More effective treatment schemes are required to improve local disease control and overall survival...
Morphometric effects of the recruitment maneuver on saline-lavaged canine lungs. A computed tomographic analysisChae Man Lim
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Anesthesiology 99:71-80. 2003..Little is known about lung-morphometric effects of the RM as compared with positive end-expiratory pressure (PEEP) titration (PT) without the RM...
Abnormal peripheral blood T-lymphocyte subsets in a subgroup of patients with COPDWon Dong Kim
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Chest 122:437-44. 2002..These findings suggest that T-lymphocyte abnormalities might be involved in the pathogenesis of airflow limitation in people who smoke...
Hypothermia protects against endotoxin-induced acute lung injury in ratsChae Man Lim
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 138 600
Intensive Care Med 29:453-9. 2003..Because an activation of circulating neutrophils and their sequestration into the lung are important pathogenetic phenomena in endotoxin-associated lung injury, we conjectured that hypothermia could prevent this type of lung injury...
Adequately washed bronchoscope does not induce false-positive amplification tests on bronchial aspirates in the diagnosis of pulmonary tuberculosisTae Sun Shim
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Chest 121:774-81. 2002....
The effects of humidity and serum on the surface microhardness and morphology of five retrograde filling materialsJ S Kang
Department of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul, Korea
Scanning 34:207-14. 2012..However, further long-term studies considering other factors, such as biocompatibility (i.e. cellular toxicity) and retention, are needed to be collaborated with these findings in the clinical context...
Right posterior portal vein stenosis developed after living donor liver transplantation using a modified right lobe graft with a type 2 portal vein: a case reportY D Yu
Department of Surgery, Division of HBP Surgery and Liver Transplantation, Korea University College of Medicine, Seoul, Korea
Transplant Proc 44:585-7. 2012....
Effects of low-level arsenic exposure on urinary N-acetyl-β-D-glucosaminidase activityS Y Eom
Department of Preventive Medicine and Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea
Hum Exp Toxicol 30:1885-91. 2011..44 U/g creatinine and especially in those who had not consumed seafood recently. These facts suggest that a relatively low-level exposure to inorganic arsenic produces renal tubular damage in humans...
Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazoleD S Kim
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
Exp Clin Endocrinol Diabetes 108:146-50. 2000..This case study would also like to point out that plasma ACTH and cortisol levels were decreased effectively by the combination of octreotide and ketoconazole in this instance of ectopic ACTH syndrome...
Effects of oncostatin M on hormone release of rat pituitary cells in primary cultureD S Kim
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
J Korean Med Sci 15:323-6. 2000..We conclude OSM has a stimulatory effect on ACTH secretion in normal rat pituitary cell cultures, and OSM acts mainly on corticotroph, supporting the potential role of OSM to modulate immune-endocrine regulation in the pituitary...
Bacille Calmette Guérin (BCG) can induce Kawasaki disease-like features in programmed death-1 (PD-1) gene knockout miceJ K Chun
Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju, Korea
Clin Exp Rheumatol 29:743-50. 2011..We investigated the associative role of programmed death-1 (PD-1) gene in the pathogenesis of KD by injecting bacilli Calmette Guérin (BCG) to PD-1 gene knockout (PD-1KO) mice...
Clonal expansion of CD8+ T cells in Kawasaki diseaseI H Choi
Department of Microbiology, Yonsei University College of Medicine, Seodaemoon ku, Seoul, Korea
J Immunol 159:481-6. 1997..Our data suggest that the conventional Ags rather than a superantigen were involved in the pathogenesis of acute KD...
Prevalence and patterns of left ventricular hypertrophy in patients with predialysis chronic renal failureS K Ha
Department of Internal Medicine, Yongdong Severance Hospital, Institute of Kidney Disease, Yonsei University, College of Medicine, Seoul, Korea
J Korean Med Sci 13:488-94. 1998..5%) was the main pattern of LVH. Several factors such as anemia, systolic and diastolic BP, renal function and PTH influence LVMI...
Circulating interleukin 17 is increased in the acute stage of Kawasaki diseaseM H Sohn
Department of Pediatrics and Institute for Immunology and Immunological Diseases, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Scand J Rheumatol 32:364-6. 2003..In the acute phase, levels of IL-6 were 83.52 +/- 19.12 pg/L, which correlated well with the serum levels of IL-17. CONCLUSION: These results suggest that IL-17 may be involved in the development of, or the effects of inflammation in KD...
Postoperative adjuvant chemotherapy and radiotherapy for stage II and III non-small cell lung cancer (NSCLC)Sang-Wook Lee
Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-dong, Songpa-Gyu, Seoul 138-736, South Korea
Lung Cancer 37:65-71. 2002..A prospective randomized trial, which compares this regimen to surgery alone or postoperative adjuvant radiotherapy is needed...
Clinical features and outcomes of idiopathic pulmonary alveolar proteinosis in Korean populationMin Kwang Byun
Division of Pulmonary Medicine, Department of Internal Medicine, Yonsei University, College of Medicine, Yonsei University Health System, Seoul, Korea
J Korean Med Sci 25:393-8. 2010..The clinical features and pulmonary parameters of Korean patients with idiopathic PAP are consistent with reports in other published studies. Whole lung lavage appears to be the most effective form of treatment...
The effects of hypothermia on endotoxin-primed lungJae Yong Chin
Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Anesth Analg 104:1171-8, tables of contents. 2007..We investigated whether hypothermia induced after the onset of such neutrophilic inflammation reduces acute lung injury...
A nationwide survey of lymphangioleiomyomatosis in Korea: recent increase in newly diagnosed patientsHye Yun Park
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
J Korean Med Sci 25:1182-6. 2010..It is concluded that the reason for the increase of newly diagnosed patients is the result of increase in detection of the early stage LAM by the widespread use of chest CT screening...
Recovery from lung injury in survivors of acute respiratory distress syndrome: difference between pulmonary and extrapulmonary subtypesSun Jong Kim
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 138-736 Songpa-gu, Seoul, Korea
Intensive Care Med 30:1960-3. 2004..CONCLUSIONS: These results suggest that ARDSp would leave more severe lung sequelae than ARDSexp, but the clinical relevance of their difference is questionable...
Association between stress and asthma symptoms: a population-based studyYeon-Mok Oh
Department of Internal Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
Respirology 9:363-8. 2004..5 (95% CI 1.0, 2.3), 2.4 (95% CI 1.6, 3.6) and 4.0 (95% CI 2.5, 6.4), respectively. CONCLUSION: This cross-sectional study shows an association between stress and asthma symptoms in the general population of South Korea...
Changes in integrity of normal-appearing white matter in patients with moyamoya disease: a diffusion tensor imaging studyH Jeong
Departments of Radiology, Yonsei University College of Medicine, Seoul, Korea
AJNR Am J Neuroradiol 32:1893-8. 2011....
Acanthamoebiasis in Korea: two new cases with clinical cases reviewK Im
Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea
Yonsei Med J 39:478-84. 1998....
Pathogenesis of arachnoid cyst: congenital or traumatic?J U Choi
Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Pediatr Neurosurg 29:260-6. 1998..An other 7 patients had a history of perinatal trauma. We postulate that head trauma in infancy may contribute to the pathogenesis of arachnoid cyst in some cases...
The causative organisms of bacterial meningitis in Korean children, 1986-1995K H Kim
Department of Pediatrics, Ewha Womans University, Seoul, Korea
J Korean Med Sci 13:60-4. 1998..pneumoniae, H. influenzae, and N. meningitidis in order of frequency. Further study should be extended to nation-wide epidemiologic evaluation to show the incidence of bacterial meningitis caused by these three important organisms...
Comparison of the efficacy and safety of tramadol/acetaminophen combination therapy and gabapentin in the treatment of painful diabetic neuropathyS H Ko
The Catholic University of Korea, Seoul, Korea
Diabet Med 27:1033-40. 2010..This study compared the efficacy and safety of tramadol/acetaminophen (T/A) and gabapentin in the management of painful diabetic neuropathy...
IgE binding patterns to German cockroach whole body extract in Korean atopic asthmatic childrenS Y Lee
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
Yonsei Med J 39:409-16. 1998..Therefore, Bla g I (25-30 kDa) and Bla g II (36 kDa) could not be the absolute indicators of German cockroach sensitization and parameters of environmental control...
Ventricular pressure monitoring during bilateral decompression with dural expansionD S Yoo
Department of Neurosurgery, Uijongbu St Mary s Hospital, The Catholic University of Korea, College of Medicine, Seoul
J Neurosurg 91:953-9. 1999....
Effects of maintaining a remifentanil infusion on the recovery profiles during emergence from anaesthesia and tracheal extubationJ S Nho
Department of Anesthesiology, Kyung Hee University Hospital, Seoul, Republic of Korea
Br J Anaesth 103:817-21. 2009..We examined the effects of maintaining a remifentanil infusion on recovery profiles such as coughing and cardiovascular responses after general anaesthesia...
MMP-2 regulates human platelet activation by interacting with integrin alphaIIbbeta3W S Choi
National Research Laboratory, Department of Biochemistry, College of Science, Yonsei University, Seoul, Korea
J Thromb Haemost 6:517-23. 2008..Platelet MMPs have been implicated in the regulation of cellular activation and aggregation. Although the proaggregatory effect of MMP-2 has been demonstrated, the functional mechanism is not clearly understood...
Clinical validation of the lower limit of normal in lung diffusing capacity: is the lower 5th percentile really the best cut-off value?Seung Won Ra
Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Respir Physiol Neurobiol 167:354-6. 2009..Thus, the 90% CI or the lower 10th percentile for the cut-off value of the LLN might be better than the 95% CI or the lower 5th percentile in differentiating subjects with pathologic proven ILD from healthy subjects...
Mortality and risk factors for surgical lung biopsy in patients with idiopathic interstitial pneumoniaJoo Hun Park
Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap dong, Songpa Gu, Seoul 138 600, Republic of Korea
Eur J Cardiothorac Surg 31:1115-9. 2007..This study was performed to investigate the mortality and complication rate and identify the risk factors for surgical lung biopsy in patients with IIP...
Is hypercapnea a predictor of better survival in the patients who underwent mechanical ventilation for chronic obstructive pulmonary disease (COPD)?Joo Hun Park
Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea
Korean J Intern Med 21:1-9. 2006..There are contradictory reports concerning hypercapnia as a predictor of a better outcome in COPD. This study examined the clinical implications of hypercapnea in COPD patients (M:F = 59:19) who required mechanical ventilation...
Nonspecific interstitial pneumonia versus usual interstitial pneumonia: differences in the density histogram of high-resolution CTKyung-Hyun Do
Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
J Comput Assist Tomogr 29:544-8. 2005..3880 +/- 1.8183). CONCLUSION: The density histogram reflected the differences in the CT features between NSIP and UIP. Therefore, a density histogram may be helpful for differentiating NSIP from UIP without definite honeycombing...
Efficacy and tolerability of daily-half dose linezolid in patients with intractable multidrug-resistant tuberculosisI-Nae Park
Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-dong, Songpa-gu, Seoul, Korea
J Antimicrob Chemother 58:701-4. 2006..CONCLUSIONS: Although daily-half doses of linezolid were effective in patients with intractable or extensive MDR-TB, this dosage regimen did not reduce long-term use-related side effects, such as peripheral and optic neuropathy...
Acute cerebral phaeohyphomycosis due to Wangiella dermatitidis accompanied by cerebrospinal fluid eosinophiliaC L Chang
Department of Clinical Pathology, College of Medicine, Pusan National University, Pusan, Korea
J Clin Microbiol 38:1965-6. 2000..The present case suggested that this black yeast-like fungus should be included when the causes of CSF eosinophilia are considered, even though it is an extremely rare pathogen...
Antibiotic use at a pediatric ageD S Kim
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
Yonsei Med J 39:595-603. 1998..In this article, we describe these peculiarities of children and discuss the proper use of antibiotics in children...
Ten-year survival of patients with locally advanced, stage ib-iib cervical cancer after neoadjuvant chemotherapy and radical hysterectomyY Y Hwang
Department of Obstetrics and Gynecology, Hanyang University School of Medicine, No. 17, Haengdang-Dong, Sungdong-Ku, Seoul, South Korea
Gynecol Oncol 82:88-93. 2001..However, randomized controlled trials are needed to confirm this result...
Endoscopic approach to arachnoid cystJ U Choi
Department of Neurosurgery, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Childs Nerv Syst 15:285-91. 1999..There was no mortality or morbidity. We conclude that endoscopic procedures may be a promising alternative to microsurgical operations or shunting for the treatment of arachnoid cysts...
Active site modification of 4-aminobutyrate aminotransferase with ATP analogsD S Kim
Department of Biochemistry, Yonsei University College of Science, Seoul, Korea
Biochim Biophys Acta 916:265-70. 1987..It is postulated that the catalytic domain of 4-aminobutyrate aminotransferase is accessible to bulky reagents of greater length than the substrates 4-aminobutyrate and alpha-ketoglutarate...
Angioimmunoblastic lymphoma (AILD-type T-cell lymphoma) with hyperplastic germinal centersH J Ree
Samsung Medical Center, Seoul, Korea
Am J Surg Pathol 22:643-55. 1998..We conclude that hyperplastic germinal centers with ill-defined borders and frequent interfollicular tingible-body macrophages occur in a histologic variant of AITL that is necessary to recognize for early diagnosis and treatment...
Treatment of intravenous immunoglobulin-resistant Kawasaki disease with methotrexateS Y Ahn
Department of Paediatrics, College of Medicine, Yonsei University, Seoul, Korea
Scand J Rheumatol 34:136-9. 2005..There was no progression of coronary artery dilatation and MTX was discontinued with no recurrence of fever. No adverse effects of MTX were observed. CONCLUSION: Low-dose oral MTX is an effective treatment for refractory KD...
Elevated anti-alpha-enolase antibody levels in Kawasaki diseaseJ K Chun
Department of Paediatrics, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea
Scand J Rheumatol 37:48-52. 2008..The role of alpha-enolase in KD was assessed by measuring anti-alpha-enolase antibody (Ab) titres in patients with KD and the usefulness of anti-alpha-enolase Ab as a diagnostic tool in atypical KD patients was evaluated...
Total occlusion of left main coronary artery by dilated main pulmonary artery in a patient with severe pulmonary hypertensionJ Lee
Cardiology Division, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, 146-92, Dogok-dong, Kangnam-gu, Seoul 135-270, Korea
Korean J Intern Med 16:265-9. 2001....
Effect of alveolar recruitment maneuver in early acute respiratory distress syndrome according to antiderecruitment strategy, etiological category of diffuse lung injury, and body position of the patientChae-Man Lim
Department of Internal Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea
Crit Care Med 31:411-8. 2003..Pulmonary ARDS and extrapulmonary ARDS may be different pathophysiologic entities. An effective ARM may obviate the need for the prone position in ARDS at least in terms of oxygenation...
A simple and easy home-based pulmonary rehabilitation programme for patients with chronic lung diseasesJoo Ock Na
Division of Pulmonary and Critical Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
Monaldi Arch Chest Dis 63:30-6. 2005..CONCLUSIONS: We developed a simple home-based pulmonary rehabilitation programme, which seems to be clinically feasible and effective...
Elevated serum CA-125 levels in patients with non-tuberculous mycobacterial lung diseaseSun Young Kim
Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Respirology 15:357-60. 2010..This study showed that serum CA-125 levels were elevated in some patients with NTM pulmonary disease. Further studies are needed to investigate the usefulness of serum CA-125 measurements in patients with NTM pulmonary disease...
