Research Topics
| G H KangSummaryAffiliation: University of Ulsan Country: Korea Publications
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Detail Information
Publications
Clinicopathologic characteristics of replication error-positive gastric carcinomaG H Kang
Department of Diagnostic Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
Mod Pathol 12:15-20. 1999..In conclusion, RER+ gastric carcinomas demonstrated distinct clinicopathologic features, and BAT-26 was a useful marker for assessing the RER status of gastric carcinomas...
Correlation of methylation of the hMLH1 promoter with lack of expression of hMLH1 in sporadic gastric carcinomas with replication errorG H Kang
Department of Pathology, Ulsan University College of Medicine, Asan Medical Center, Seoul, Korea
Lab Invest 79:903-9. 1999..These results suggest that hypermethylation of the hMLH1 promoter region may be the principal mechanism of gene inactivation in sporadic gastric carcinomas with a high frequency of MSI...
Gross type-matched study of clinicopathologic features of advanced gastric carcinoma with replication errorG H Kang
Department of Diagnostic Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Pathol Int 49:1053-9. 1999..Most of the previously known clinicopathological features of RER+ AGC were related to Borrmann type 2, except for female sex, older age, expanding pattern, and low DNA index...
Methylation of the hMLH1 promoter in multiple gastric carcinomas with microsatellite instabilityH Y Jung
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Pathol Int 51:445-51. 2001..None of the tumors showed hMSH2 hypermethylation. These results suggest that epigenetic changes in the hMLH1 promoter account for the genesis of multiple gastric carcinoma with high frequency MSI...
CpG island methylation in premalignant stages of gastric carcinomaG H Kang
Department of Pathology, Seoul National University College of Medicine and Cancer Research Institute, Korea
Cancer Res 61:2847-51. 2001..001) as well as from premalignant lesions to carcinomas (P = 0.002). These results suggest that CpG island hypermethylation occur early in multistep gastric carcinogenesis and tend to accumulate along the multistep carcinogenesis...
Somatic mutations of the first 14 exons of APC in hamartomatous polyps of the colonJ C Kim
Laboratory of Gastrointestinal Cancer Biology and Genetics, Department of Surgery, University of Ulsan College of Medicine and Asan Institute for Life Sciences, 388 1 Poongnap dong, Songpa Ku, Seoul, Korea
Hum Mutat 14:351-2. 1999..Since all mutations were missense or silent mutations occurred in exons not previously known to have functionally relevant area, their phenotypic implication appeared to be limited...
Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomasY H Shim
Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
Lab Invest 80:689-95. 2000..The relatively high frequency of hypermethylation on p16 and the strong correlation between the immunoreactivity and methylation patterns suggest that methylation is an important mechanism for p16 gene inactivation in GC...
Isolated splenic metastasis from colorectal carcinoma: a case reportJ C Kim
Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
J Korean Med Sci 15:355-8. 2000..As all reported cases showed elevated serum CEA at the time of metastasis, isolated splenic metastasis might be associated with CEA in regard to its biological functions of immunosuppression and adhesion...
Efficiency of combined colonoscopy and computed tomography for diagnosis of colonic actinomycosis: a retrospective evaluation of eight consecutive patientsJ C Kim
Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
Int J Colorectal Dis 15:236-42. 2000..A combination of colonoscopy and CT appears to be important for both diagnosis and management because of their compensatory findings of mucosal and extramucosal lesions, respectively...
Applicability of carcinoembryonic antigen-specific monoclonal antibodies to radioimmunoguided surgery for human colorectal carcinomaJ C Kim
Department of Surgery, University of Ulsan College of Medicine and Asan Institute for Life Sciences, Seoul, Korea
Cancer Res 60:4825-9. 2000..66-pretreated mice. A study using specific anti-CEA MAbs suggested PR1A3 as an efficient immune probe for RIGS in colorectal carcinoma with a low rate of false-positive detection...
Pelioid-type hepatocellular carcinoma masquerading as a hepatic hemangioma on technetium-99m red blood cell scintigraphyE K Ji
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Clin Nucl Med 26:33-5. 2001..Pathologic examination showed that the portion of the hepatocellular carcinoma that showed increased uptake on Tc-99m RBC scintigraphy had peliosis, which is the likely cause of the radiotracer avidity...
Papillary immature metaplasia of the uterine cervix: a report of 5 cases with an emphasis on the differential diagnosis from reactive squamous metaplasia, high-grade squamous intraepithelial lesion and papillary squamous cell carcinomaG H Kang
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
J Korean Med Sci 16:762-8. 2001..There were no significant differences of Ki-67 labeling index and mitotic index between PIM and SM. The expression of p53 varied among the groups and thus it was not helpful for the differential diagnosis...
Source of errors in the evaluation of early rectal cancer by endoluminal ultrasonographyJ C Kim
Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea
Dis Colon Rectum 44:1302-9. 2001..1 percent) of the 28 errors might have been avoided. Therefore, a clear image by endoluminal sonography can effectively distinguish mucosal from submucosal lesions in early rectal cancer...
DNA hypermethylation in gastric cancerT Y Kim
National Research Laboratory for Cancer Epigenetics, Cancer Research Institute, Seoul, Korea
Aliment Pharmacol Ther 20:131-42. 2004..A better understanding of DNA hypermethylation will provide us with new opportunities in the diagnosis and therapy of gastric cancer...
Hypermethylation of CpG island loci and hypomethylation of LINE-1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological featuresN Y Cho
Laboratory of Epigenetics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
J Pathol 211:269-77. 2007....
