Ki Hoon Han

Summary

Affiliation: University of Ulsan
Country: Korea

Publications

  1. doi request reprint Vascular expression of the chemokine CX3CL1 promotes osteoclast recruitment and exacerbates bone resorption in an irradiated murine model
    Ki Hoon Han
    Department of Cardiology, School of Medicine, University of Ulsan, Asan Medical Center, Seoul 138 736, Republic of Korea Electronic address
    Bone 61:91-101. 2014
  2. pmc The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine
    Mi Kyung Chang
    University of Ulsan College of Medicine, Asan Medical Center, 388 1 Pungnap 2 dong Songpa gu 138 736, Seoul, South Korea
    J Inflamm (Lond) 9:42. 2012
  3. ncbi request reprint HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo
    Ki Hoon Han
    Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
    Circulation 111:1439-47. 2005
  4. ncbi request reprint C-reactive protein promotes monocyte chemoattractant protein-1--mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes
    Ki Hoon Han
    Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Circulation 109:2566-71. 2004
  5. doi request reprint CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages
    Ki Hoon Han
    Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul, Republic of Korea
    Cardiovasc Res 84:378-86. 2009
  6. ncbi request reprint Incidence, mechanism, predictors, and long-term prognosis of late stent malapposition after bare-metal stent implantation
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Cardiac Center, Asan Medical Center, Seoul, Korea
    Circulation 109:881-6. 2004
  7. ncbi request reprint Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era
    Tae Hyun Yang
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 96:1389-92. 2005
  8. ncbi request reprint Comparison of coronary plaque rupture between stable angina and acute myocardial infarction: a three-vessel intravascular ultrasound study in 235 patients
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Circulation 110:928-33. 2004
  9. ncbi request reprint FcgammaRIIa mediates C-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4
    Jewon Ryu
    Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Cardiovasc Res 75:555-65. 2007
  10. ncbi request reprint Two-year follow-up of the quantitative angiographic and volumetric intravascular ultrasound analysis after nonpolymeric paclitaxel-eluting stent implantation: late "catch-up" phenomenon from ASPECT Study
    Duk Woo Park
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Am Coll Cardiol 48:2432-9. 2006

Collaborators

Detail Information

Publications51

  1. doi request reprint Vascular expression of the chemokine CX3CL1 promotes osteoclast recruitment and exacerbates bone resorption in an irradiated murine model
    Ki Hoon Han
    Department of Cardiology, School of Medicine, University of Ulsan, Asan Medical Center, Seoul 138 736, Republic of Korea Electronic address
    Bone 61:91-101. 2014
    ..These results demonstrate that the de novo CX3CL1-CX3CR1 axis plays a pivotal role in osteoclast recruitment and subsequent bone resorption, and verify its therapeutic potential as a new target for anti-resorptive treatment. ..
  2. pmc The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine
    Mi Kyung Chang
    University of Ulsan College of Medicine, Asan Medical Center, 388 1 Pungnap 2 dong Songpa gu 138 736, Seoul, South Korea
    J Inflamm (Lond) 9:42. 2012
    ..CONCLUSIONS: The formation of complexes between CRP and PC-containing oxPLs, such as LPC, suppresses the pro-atherogenic effects of CRP and LPC on macrophages. This effect may in part retard the progression of atherosclerosis...
  3. ncbi request reprint HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo
    Ki Hoon Han
    Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
    Circulation 111:1439-47. 2005
    ..The present study investigated whether 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibition affects CCR2 gene expression and CCR2-dependent monocyte recruitment...
  4. ncbi request reprint C-reactive protein promotes monocyte chemoattractant protein-1--mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes
    Ki Hoon Han
    Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Circulation 109:2566-71. 2004
    ..In addition, recent data suggest that CRP may directly promote atherogenesis. In this study, we investigated whether CRP can directly activate human circulating monocytes...
  5. doi request reprint CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages
    Ki Hoon Han
    Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul, Republic of Korea
    Cardiovasc Res 84:378-86. 2009
    ..We investigated the mechanism by which cannabinoid receptors-1 (CB1) and -2 (CB2) modulate inflammatory activities of macrophages...
  6. ncbi request reprint Incidence, mechanism, predictors, and long-term prognosis of late stent malapposition after bare-metal stent implantation
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Cardiac Center, Asan Medical Center, Seoul, Korea
    Circulation 109:881-6. 2004
    ..Predictors and long-term prognosis of late stent malapposition (LSM) after bare-metal stent (BMS) implantation are unknown...
  7. ncbi request reprint Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era
    Tae Hyun Yang
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 96:1389-92. 2005
    ..In conclusion, in this study of real-world patients who underwent DES implantation, patients who had DM had restenotic rates and clinical outcomes that were similar to those in patients who did not have DM...
  8. ncbi request reprint Comparison of coronary plaque rupture between stable angina and acute myocardial infarction: a three-vessel intravascular ultrasound study in 235 patients
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Circulation 110:928-33. 2004
    ..We evaluated the incidence and predictors of single and multiple plaque ruptures in acute myocardial infarction (AMI) and stable angina pectoris (SAP)...
  9. ncbi request reprint FcgammaRIIa mediates C-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4
    Jewon Ryu
    Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Cardiovasc Res 75:555-65. 2007
    ..We investigated the mechanism by which C-reactive protein (CRP) affects pro-inflammatory activities of vascular smooth muscle cells (VSMCs)...
  10. ncbi request reprint Two-year follow-up of the quantitative angiographic and volumetric intravascular ultrasound analysis after nonpolymeric paclitaxel-eluting stent implantation: late "catch-up" phenomenon from ASPECT Study
    Duk Woo Park
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Am Coll Cardiol 48:2432-9. 2006
    ..This study used serial angiographic and intravascular ultrasound (IVUS) analysis to evaluate the long-term efficacy of a nonpolymeric, paclitaxel-eluting stent coating on intimal hyperplasia (IH) 2 years after implantation...
  11. ncbi request reprint Intravascular ultrasound assessment of patterns of arterial remodeling in the absence of significant reference segment plaque burden in patients with coronary artery disease
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap2 Dong, Songpa Gu, Seoul 138 736, South Korea
    J Am Coll Cardiol 42:806-10. 2003
    ..Intravascular ultrasound (IVUS) assessment of lesion remodeling compares lesions to reference segments. However, reference segments are rarely disease-free and, therefore, have also undergone remodeling changes...
  12. ncbi request reprint Usefulness of follow-up low-density lipoprotein cholesterol level as an independent predictor of changes of coronary atherosclerotic plaque size as determined by intravascular ultrasound analysis after statin (atorvastatin or simvastatin) therapy
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 98:866-70. 2006
    ..Aggressive lipid-lowering treatments with statins to decrease the follow-up LDL cholesterol level to <100 mg/dl are recommended...
  13. ncbi request reprint Late stent malapposition after drug-eluting stent implantation: an intravascular ultrasound analysis with long-term follow-up
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Circulation 113:414-9. 2006
    ..Late stent malapposition (LSM) after drug-eluting stent (DES) implantation has not been evaluated sufficiently in real-world practice...
  14. ncbi request reprint Comparison of cilostazol and clopidogrel after successful coronary stenting
    Seung Whan Lee
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 95:859-62. 2005
    ..6% each) did not differ statistically between groups. These results indicate that cilostazol is as safe and effective as clopidogrel in preventing thrombotic complications after stenting...
  15. ncbi request reprint Late intravascular ultrasound findings of patients treated with brachytherapy for diffuse in-stent restenosis
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
    Catheter Cardiovasc Interv 63:208-14. 2004
    ..However, quantitative evidence of late catch-up was evident in most patients and was significantly associated with 24-month TLR in some patients...
  16. ncbi request reprint Comparison between sirolimus- and Paclitaxel-eluting stents for the treatment of chronic total occlusions
    Jae Sik Jang
    Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    J Invasive Cardiol 18:205-8. 2006
    ..This study evaluated the clinical and angiographic effectiveness of sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) implantation for chronic total occlusion (CTO) lesions...
  17. ncbi request reprint Paclitaxel coating reduces in-stent intimal hyperplasia in human coronary arteries: a serial volumetric intravascular ultrasound analysis from the Asian Paclitaxel-Eluting Stent Clinical Trial (ASPECT)
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Songpa Gu, Seoul, Korea
    Circulation 107:517-20. 2003
    ..The aim of this study was to use serial volumetric intravascular ultrasound (IVUS) to evaluate the effect of a paclitaxel coating on in-stent intimal hyperplasia (IH)...
  18. doi request reprint Comparison of zotarolimus-eluting stents with sirolimus-eluting and paclitaxel-eluting stents: intimal hyperplasia and vascular changes assessed by volumetric intravascular ultrasound analysis
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Circ Cardiovasc Interv 4:139-45. 2011
    ....
  19. ncbi request reprint Comparison of simple and complex stenting techniques in the treatment of unprotected left main coronary artery bifurcation stenosis
    Young Hak Kim
    The Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 97:1597-601. 2006
    ..Compared with the complex stenting technique, the simple technique was technically easier and appeared to be more effective in improving long-term outcomes in patients with normal LCxs...
  20. doi request reprint Long-term vascular changes after drug-eluting stent implantation assessed by serial volumetric intravascular ultrasound analysis
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 105:1402-8. 2010
    ..In conclusion, although IH continued to increase beyond 6 months, the growth rate of intima and luminal loss attenuated with time...
  21. ncbi request reprint Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia
    Jewon Ryu
    Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap 2 dong Songpa gu 138 736, Seoul 138 736, Republic of Korea
    Cardiovasc Res 78:333-40. 2008
    ..The present study investigated the detailed mechanism by which fractalkine (Fkn), a CX3C chemokine, induces angiogenesis and its functional implication in alleviating ischaemia in vivo...
  22. ncbi request reprint Bail-out stenting for left main coronary artery dissection during catheter-based procedure: acute and long-term results
    Seung Whan Lee
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Clin Cardiol 27:393-5. 2004
    ..The optimal treatment of patients with left main coronary artery (LMCA) dissection during catheter-based procedure remains uncertain...
  23. doi request reprint Tissue characterization of in-stent neointima using intravascular ultrasound radiofrequency data analysis
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 106:1561-5. 2010
    ..In conclusion, this VH-IVUS analysis showed that BMS- and DES-treated lesions develop in-stent necrotic core and dense calcium, suggesting the development of in-stent neoatherosclerosis...
  24. doi request reprint Duration of dual antiplatelet therapy after implantation of drug-eluting stents
    Seung Jung Park
    Department of Cardiology, Center for Medical Research and Information, University of Ulsan College of Medicine, Seoul, South Korea
    N Engl J Med 362:1374-82. 2010
    ..The potential benefits and risks of the use of dual antiplatelet therapy beyond a 12-month period in patients receiving drug-eluting stents have not been clearly established...
  25. ncbi request reprint The site of plaque rupture in native coronary arteries: a three-vessel intravascular ultrasound analysis
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Am Coll Cardiol 46:261-5. 2005
    ..We evaluated the axial location of plaque ruptures in native coronary arteries...
  26. doi request reprint Tumor necrosis factor-alpha potentiates RhoA-mediated monocyte transmigratory activity in vivo at a picomolar level
    Sunny Lim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Arterioscler Thromb Vasc Biol 29:2138-45. 2009
    ..We investigated whether these picomolar levels of TNF-alpha directly modulate the functional activities of circulating monocytes...
  27. ncbi request reprint Early and late clinical outcomes after primary stenting of the unprotected left main coronary artery stenosis in the setting of acute myocardial infarction
    Seung Whan Lee
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap dong, Songpa Gu, Seoul 138 736, South Korea
    Int J Cardiol 97:73-6. 2004
    ..The study was aimed to evaluate the effect of primary stenting in patients with left main coronary artery (LMCA) disease in the setting of acute myocardial infarction (AMI)...
  28. ncbi request reprint Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Catheter Cardiovasc Interv 65:247-53. 2005
    ..However, IH progression was observed in 24% of in-stent lesions. No significant changes of EEM or lumen area occurred in the reference segments...
  29. ncbi request reprint Randomized comparison of debulking followed by stenting versus stenting alone for ostial left anterior descending artery stenosis: intravascular ultrasound guidance
    Young Hak Kim
    Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Am Heart J 148:663-9. 2004
    ..This study was aimed to evaluate the effect of DCA followed by stenting on ostial LAD stenosis under the guidance of intravascular ultrasound (IVUS)...
  30. doi request reprint Late and very late drug-eluting stent malapposition: serial 2-year quantitative IVUS analysis
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, Korea
    Circ Cardiovasc Interv 3:335-40. 2010
    ..The long-term natural history of acquired malapposition continues to be the subject of debate...
  31. doi request reprint Mechanisms of in-stent restenosis after drug-eluting stent implantation: intravascular ultrasound analysis
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Circ Cardiovasc Interv 4:9-14. 2011
    ..We used intravascular ultrasound (IVUS) to (1) clarify the mechanisms of luminal loss after drug-eluting stent (DES) implantation and (2) classify morphological patterns of in-stent restenosis (ISR)...
  32. ncbi request reprint C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression
    Yuna Kim
    Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    FEBS Lett 588:625-31. 2014
    ..Therefore the pro-apoptotic pathway of CRP-CD32-Nox2-p53-BTG2 may contribute to the retardation of the atherogenic process. ..
  33. ncbi request reprint Diabetic retinopathy as a predictor of late clinical events following percutaneous coronary intervention
    Young Hak Kim
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap dong, Songpa Gu, Seoul, 138 736, Korea
    J Invasive Cardiol 14:599-602. 2002
    ..17). In conclusion, the presence of retinopathy might be a predictor of mortality after PCI in DM patients; however, it might not be related to the development of other major cardiac and cerebrovascular events...
  34. ncbi request reprint Serial intravascular ultrasound evidence of both plaque stabilization and lesion progression in patients with ruptured coronary plaques: effects of statin therapy on ruptured coronary plaque
    Myeong Ki Hong
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
    Atherosclerosis 191:107-14. 2007
    ..Conversely, healing of non-statin-treated non-culprit/non-target lesion plaque ruptures can be responsible for lesion progression requiring revascularization...
  35. ncbi request reprint Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration
    Je Won Ryu
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Arterioscler Thromb Vasc Biol 24:864-70. 2004
    ..Here we investigated whether UCP2 regulates expression of genes involved in monocyte recruitment...
  36. ncbi request reprint Comparison of angiographic patterns of in-stent restenosis between sirolimus- and paclitaxel-eluting stent
    Chang Bum Park
    Department of Internal Medicine, Seoul Veterans Hospital, Seoul, South Korea
    Int J Cardiol 120:387-90. 2007
    ..But the different angiographic patterns of ISR and its prognosis between sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) has not been properly addressed in large scale studies...
  37. pmc Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty
    Hyun Suk Yang
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Korean J Intern Med 20:21-5. 2005
    ....
  38. ncbi request reprint Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis
    Seung Whan Lee
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Am Coll Cardiol 46:1833-7. 2005
    ..We evaluated safety and efficacy of triple antiplatelet therapy with aspirin, clopidogrel, or ticlopidine and cilostazol after coronary stenting...
  39. doi request reprint Effect of intravascular ultrasound findings on long-term repeat revascularization in patients undergoing drug-eluting stent implantation for severe unprotected left main bifurcation narrowing
    Soo Jin Kang
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Am J Cardiol 107:367-73. 2011
    ....
  40. ncbi request reprint Lysophosphatidylcholine up-regulates CXCR4 chemokine receptor expression in human CD4 T cells
    Ki Hoon Han
    College of Medicine, Asan Medical Center, 388 1 Pungnap 2 dong, Songpa Gu 138 736, Seoul, South Korea
    J Leukoc Biol 76:195-202. 2004
    ..The data suggest that the presence of lysoPC and SDF-1 in atherosclerotic lesions may trigger inflammatory responses mediated by CD4 T cells, which may play an important role in progression of atherosclerosis...
  41. ncbi request reprint Five-year outcomes after stenting of unprotected left main coronary artery stenosis in patients with normal left ventricular function
    Bong Ki Lee
    Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University College of Medicine, Chunchon, Kangwon Do, Korea
    Int J Cardiol 115:208-13. 2007
    ..We analyzed the long-term (5-year) outcome of patients treated with stenting for unprotected left main coronary artery (LMCA) stenosis...
  42. ncbi request reprint Proteomic analysis of differential protein expression in neuropathic pain and electroacupuncture treatment models
    Ho Joong Sung
    Asan Institute for Life Sciences, Asan Medical Center, Seoul, South Korea
    Proteomics 4:2805-13. 2004
    ..Potential applications of our results include the identification and characterization of signaling pathways involved in EA treatment and further exploration of the role of selected identified proteins in the animal model...
  43. ncbi request reprint Differential effects of 9-cis retinoic acid on expression of CC chemokine receptors in human monocytes
    In Sik Kim
    Department of Clinical Laboratory Science, School of Medicine, Eulji University, Daejun 301 832, South Korea
    Biochem Pharmacol 68:611-20. 2004
    ....
  44. ncbi request reprint Early and late clinical outcomes after rotational atherectomy with stenting versus rotational atherectomy with balloon angioplasty for complex coronary lesions
    Seung Whan Lee
    Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Poongnap dong, Songpa Gu, Seoul, 138 736, Korea
    J Invasive Cardiol 16:406-9. 2004
    ..Compared with rotational atherectomy plus balloon angioplasty, routine stenting after rotational atherectomy does not provide additional benefits in the clinical outcomes in complex coronary lesions...
  45. ncbi request reprint Monocyte chemoattractant protein-1-induced angiogenesis is mediated by vascular endothelial growth factor-A
    Kyung Hee Hong
    Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, 388 1 Pungnap 2 dong Songpa gu 138 736, Seoul, South Korea
    Blood 105:1405-7. 2005
    ..These results suggest that MCP-1-induced angiogenesis is composed largely of 2 sequential steps: the induction of VEGF-A gene expression by MCP-1 and the subsequent VEGF-A-induced angiogenesis...
  46. doi request reprint Evaluation of short-term safety and efficacy of HMG-CoA reductase inhibitors in hypercholesterolemic patients with elevated serum alanine transaminase concentrations: PITCH study (PITavastatin versus atorvastatin to evaluate the effect on patients with hy
    Ki Hoon Han
    Asan Medical Center, University of Ulsan, 388 1 Pungnap 2 dong Songpa gu 138 736, Seoul, Republic of Korea
    J Clin Lipidol 6:340-51. 2012
    ..We evaluated the safety and efficacy of the 3-hydroxyl-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and pitavastatin in patients with mild-to-moderate increased levels of hepatic enzymes...
  47. ncbi request reprint LDL activates signaling pathways leading to an increase in cytosolic free calcium and stimulation of CD11b expression in monocytes
    Ki Hoon Han
    Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
    J Lipid Res 44:1332-40. 2003
    ..In a previous study, we showed that LDL induces the expression of CCR2 in monocytes. We conclude that this may be the underlying cause of the enhanced chemokine effect on CD11b expression and activation observed with these cells...
  48. ncbi request reprint Inhibition of the angiogenesis by the MCP-1 (monocyte chemoattractant protein-1) binding peptide
    Mee Young Kim
    Department of Molecular Biology, Institute of Nanosensor and Biotechnology, Dankook University, Hannam dong san 8, Yongsan Ku, Seoul 140 714, Republic of Korea
    FEBS Lett 579:1597-601. 2005
    ..Our observations indicate that the MCP-1-binding peptide exerts its anti-angiogenic effect by interfering with the interaction between MCP-1 and its receptor...
  49. ncbi request reprint The CC chemokine MCP-1 stimulates surface expression of CX3CR1 and enhances the adhesion of monocytes to fractalkine/CX3CL1 via p38 MAPK
    Simone R Green
    Department of Medicine, University of California, San Diego, La Jolla, 92093, USA
    J Immunol 176:7412-20. 2006
    ..Together, our data suggest that a chemokine signal is required for firm CX3CR1-dependent adhesion and demonstrate that CCR2 is an important regulator of CX3CL1-dependent leukocyte adhesion...