Kun Ho Yoon

Summary

Affiliation: The Catholic University of Korea
Country: Korea

Publications

  1. ncbi request reprint Epidemic obesity and type 2 diabetes in Asia
    Kun Ho Yoon
    Divison of Endocrinology and Metabolism, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea
    Lancet 368:1681-8. 2006
  2. ncbi request reprint The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men
    Ki Won Oh
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Sacred Heart Hospital, Hallym University, Pyungchon dong, Dongan Gu, Anyang City, Kyungki do, Chunchon, Korea
    Clin Endocrinol (Oxf) 63:131-8. 2005
  3. ncbi request reprint Hyperglycemia and hyperinsulinemia have additive effects on activation and proliferation of pancreatic stellate cells: possible explanation of islet-specific fibrosis in type 2 diabetes mellitus
    Oak kee Hong
    Immunology and Cell Biology Core Laboratory, Catholic Research Institutes of Medical Science, The Catholic University of Korea, Seoul, Korea
    J Cell Biochem 101:665-75. 2007
  4. ncbi request reprint Effectiveness and safety of a glucose data-filtering system with automatic response software to reduce the physician workload in managing type 2 diabetes
    Jae Hyoung Cho
    Department of Endocrinology and Metabolism, Catholic University of Korea, Seoul, Korea
    J Telemed Telecare 17:257-62. 2011
  5. pmc Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells
    Young Hye You
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
    Diabetes Metab J 35:119-29. 2011
  6. pmc Ubiquitous Diabetes Management System via Interactive Communication Based on Information Technologies: Clinical Effects and Perspectives
    Jae Hyoung Cho
    Department of Endocrinology, Seoul St Mary s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
    Korean Diabetes J 34:267-73. 2010
  7. pmc Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
    Bj rn Tyrberg
    UCSD Cancer Center, La Jolla, CA 92037 0912, USA
    BMC Endocr Disord 2:2. 2002
  8. ncbi request reprint Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
    Kun Ho Yoon
    Department of Endocrinology and Metabolism, Immunology, and Cell Biology Core Laboratory, Institutes of Medical Science, The Catholic University of Korea, Seoul, Korea 137 701
    J Clin Endocrinol Metab 88:2300-8. 2003
  9. ncbi request reprint Ramipril treatment suppresses islet fibrosis in Otsuka Long-Evans Tokushima fatty rats
    Seung Hyun Ko
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Immunology and Cell Biology Core Laboratory, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 316:114-22. 2004
  10. ncbi request reprint Proteomic analysis of differential protein expression in response to epidermal growth factor in neonatal porcine pancreatic cell monolayers
    Oak kee Hong
    Immunology and Cell Biology Core Laboratory, Catholic Research Institutes of Medical Science, The Catholic University of Korea, Banpo dong, Seocho Ku, Seoul, Korea
    J Cell Biochem 95:769-81. 2005

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Epidemic obesity and type 2 diabetes in Asia
    Kun Ho Yoon
    Divison of Endocrinology and Metabolism, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea
    Lancet 368:1681-8. 2006
    ..At the level of primary prevention, such programmes can be linked to other non-communicable disease prevention programmes that target lifestyle-related issues. The cost of inaction is clear and unacceptable...
  2. ncbi request reprint The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men
    Ki Won Oh
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Sacred Heart Hospital, Hallym University, Pyungchon dong, Dongan Gu, Anyang City, Kyungki do, Chunchon, Korea
    Clin Endocrinol (Oxf) 63:131-8. 2005
    ..We therefore examined whether the serum adipocytokine and ghrelin levels, markers of fat metabolism, are associated with BMD in male adults...
  3. ncbi request reprint Hyperglycemia and hyperinsulinemia have additive effects on activation and proliferation of pancreatic stellate cells: possible explanation of islet-specific fibrosis in type 2 diabetes mellitus
    Oak kee Hong
    Immunology and Cell Biology Core Laboratory, Catholic Research Institutes of Medical Science, The Catholic University of Korea, Seoul, Korea
    J Cell Biochem 101:665-75. 2007
    ..Thus, hyperglycemia and hyperinsulinemia are two crucial mitogenic factors that activate and proliferate PSCs, and the presence of both states will amplify this response...
  4. ncbi request reprint Effectiveness and safety of a glucose data-filtering system with automatic response software to reduce the physician workload in managing type 2 diabetes
    Jae Hyoung Cho
    Department of Endocrinology and Metabolism, Catholic University of Korea, Seoul, Korea
    J Telemed Telecare 17:257-62. 2011
    ..The results suggest that it could improve the cost-effectiveness of online communication systems and form the basis of future clinical applications...
  5. pmc Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells
    Young Hye You
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
    Diabetes Metab J 35:119-29. 2011
    ..PDX-1/VP16, BETA2/NeuroD, and MafA overexpression have been shown to influence the differentiation and proliferation of pancreatic stem cells. However, few studies have been conducted using adult animal pancreatic stem cells...
  6. pmc Ubiquitous Diabetes Management System via Interactive Communication Based on Information Technologies: Clinical Effects and Perspectives
    Jae Hyoung Cho
    Department of Endocrinology, Seoul St Mary s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
    Korean Diabetes J 34:267-73. 2010
    ..Further investigations to demonstrate the clinical outcomes of such a system should be conducted, hopefully leading to a new paradigm of diabetes management...
  7. pmc Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
    Bj rn Tyrberg
    UCSD Cancer Center, La Jolla, CA 92037 0912, USA
    BMC Endocr Disord 2:2. 2002
    ..An increase of Ogg1 in islet cell mitochondria is consistent with a model in which hyperglycemia and consequent increased beta-cell oxidative metabolism lead to DNA damage and the induction of Ogg1 expression...
  8. ncbi request reprint Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
    Kun Ho Yoon
    Department of Endocrinology and Metabolism, Immunology, and Cell Biology Core Laboratory, Institutes of Medical Science, The Catholic University of Korea, Seoul, Korea 137 701
    J Clin Endocrinol Metab 88:2300-8. 2003
    ..Moreover, decreased beta-cell but increased alpha-cell proportion in the islets suggests for a selective beta-cell loss in the pathogenesis of Korean type 2 diabetes...
  9. ncbi request reprint Ramipril treatment suppresses islet fibrosis in Otsuka Long-Evans Tokushima fatty rats
    Seung Hyun Ko
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Immunology and Cell Biology Core Laboratory, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 316:114-22. 2004
    ..To our knowledge, this is the first report suggesting the potential effect of ramipril on the prevention of islet destruction by fibrosis in the animal model of type 2 diabetes mellitus...
  10. ncbi request reprint Proteomic analysis of differential protein expression in response to epidermal growth factor in neonatal porcine pancreatic cell monolayers
    Oak kee Hong
    Immunology and Cell Biology Core Laboratory, Catholic Research Institutes of Medical Science, The Catholic University of Korea, Banpo dong, Seocho Ku, Seoul, Korea
    J Cell Biochem 95:769-81. 2005
    ..HnRNP A2/B1, hemoglobin, cyclin A1, and ACE2 may play roles in the proliferation of epithelial cells in response to EGF...
  11. ncbi request reprint Long-term effect of the Internet-based glucose monitoring system on HbA1c reduction and glucose stability: a 30-month follow-up study for diabetes management with a ubiquitous medical care system
    Jae Hyoung Cho
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    Diabetes Care 29:2625-31. 2006
    ..To investigate the long-term effectiveness of the Internet-based glucose monitoring system (IBGMS) on glucose control in patients with type 2 diabetes...
  12. ncbi request reprint The effect of rosiglitazone on serum lipoprotein(a) levels in Korean patients with type 2 diabetes mellitus
    Seung Hyun Ko
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea, South Korea
    Metabolism 52:731-4. 2003
    ....
  13. pmc Relationship between vitamin D, parathyroid hormone, and bone mineral density in elderly Koreans
    Guilsun Kim
    Department of Internal Medicine, Division of Endocrinology and Metabolism, Seoul St Mary s Hospital, The Catholic University of Korea, Seoul, Korea
    J Korean Med Sci 27:636-43. 2012
    ..Older people seemingly need higher 25(OH)D levels to offset age-associated hyperparathyroidism. Elderly vitamin D-inadequate women in the winter are most vulnerable to age-associated hyperparathyroidism...
  14. doi request reprint Both sitagliptin analogue & pioglitazone preserve the beta-cell proportion in the islets with different mechanism in non-obese and obese diabetic mice
    Jin A Yeom
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul
    BMB Rep 44:713-8. 2011
    ..BMB reports 2011; 44(11): 713-718]...
  15. ncbi request reprint Differentially up-regulated genes in proliferating porcine neonatal pancreas cells caused by epidermal growth factor
    Sung Yoon Jeon
    Department of Endocrinology and Metabolism, Immunology and Cell Biology Core Laboratory, The Catholic University of Korea, Seoul, Korea
    J Cell Biochem 91:354-64. 2004
    ..We confirmed the up-regulation of these genes by Northern blot and semi-quantitative RT-PCR at various time points. The present findings opened new targets for the research on the mechanisms of pancreatic duct cell proliferation by EGF...
  16. ncbi request reprint Development of web-based diabetic patient management system using short message service (SMS)
    Hyuk Sang Kwon
    Department of Internal Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Bapo Dong, Seocho Ku, Seoul 137 701, Republic of Korea
    Diabetes Res Clin Pract 66:S133-7. 2004
    ..0% after applying this program to patients with the HbA1c of 7% or higher at baseline (P = 0.010). We propose this web-based diabetic patient management system as a new tool for communication between health care providers and patients...
  17. doi request reprint Insulin resistance and inflammation may have an additional role in the link between cystatin C and cardiovascular disease in type 2 diabetes mellitus patients
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, St Vincent s Hospital, Suwon 442 723, Korea
    Metabolism 59:241-6. 2010
    ..These components may have a role in addition to that of eGFR in explaining the link between cystatin C and CVD in type 2 diabetes mellitus patients...
  18. doi request reprint Rapamycin suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters
    Cheng lin Sun
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    Transplantation 90:717-24. 2010
    ..Herein, we evaluated the effects of rapamycin on porcine neonatal pancreas cell clusters (NPCCs), which primarily comprised pancreatic precursors, and attempted to find an intracellular mechanism about the harmful effects of rapamycin...
  19. ncbi request reprint Association of serum bone morphogenetic protein 4 levels with obesity and metabolic syndrome in non-diabetic individuals
    Jang Won Son
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, 62 Yeoido Dong, Seoul, Korea
    Endocr J 58:39-46. 2011
    ..Whether BMP-4 may be involved in the pathogenesis of obesity and metabolic syndrome deserves further investigation...
  20. ncbi request reprint High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system
    Seung Hyun Ko
    Department of Internal Medicine, Division of Endocrinology and Metabolism, The Catholic University of Korea, Seoul
    J Cell Biochem 98:343-55. 2006
    ..The data suggest that pancreatic inflammation and fibrosis aggravated by hyperglycemia, and Ang II play an important role in this pathogenesis...
  21. ncbi request reprint Establishment of blood glucose monitoring system using the internet
    Hyuk Sang Kwon
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    Diabetes Care 27:478-83. 2004
    ..The Internet is used worldwide as a communication tool. To improve the quality of diabetes control, we investigated the effectiveness of an Internet-based blood glucose monitoring system (IBGMS) on controlling the changes in HbA(1c) levels...
  22. ncbi request reprint A comparative study of the effects of a dipeptidyl peptidase-IV inhibitor and sulfonylurea on glucose variability in patients with type 2 diabetes with inadequate glycemic control on metformin
    Hun Sung Kim
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    Diabetes Technol Ther 15:810-6. 2013
    ..This study aimed to compare the effects of sitagliptin on glycemic change and 24-h blood glucose variability with those of the sulfonylurea glimepiride...
  23. pmc Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice
    Young Eun Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    PLoS ONE 7:e50412. 2012
    ..These findings suggest that RSV may have a therapeutic implication in the prevention and management of diabetes...
  24. ncbi request reprint Prevalence, awareness, treatment, and control of hypertension among people over 40 years old in a rural area of South Korea: The Chungju Metabolic Disease Cohort (CMC) Study
    Hong Seok Lee
    Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul 137 701, South Korea
    Clin Exp Hypertens 32:166-78. 2010
    ..Our findings indicate that appropriate health care should be given to hypertensive subjects on the basis of these risk factors and according to their sex...
  25. doi request reprint Identifying latent autoimmune diabetes in adults in Korea: the role of C-peptide and metabolic syndrome
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Diabetes Res Clin Pract 83:e62-5. 2009
    ..The prevalence of LADA was 5.1%. Low C-peptide level and absence of metabolic syndrome were variables independently associated with the diagnosis of LADA...
  26. ncbi request reprint Identifying metabolically obese but normal-weight (MONW) individuals in a nondiabetic Korean population: the Chungju Metabolic disease Cohort (CMC) study
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    Clin Endocrinol (Oxf) 75:475-81. 2011
    ..To investigate the prevalence and identify the phenotype of individuals suspected to be metabolically obese but normal weight (MONW)...
  27. doi request reprint Rosiglitazone protects the pancreatic beta-cell death induced by cyclosporine A
    Ji Won Kim
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 390:763-8. 2009
    ..Thus, Rosi signaling directly modulates the ER stress response, promoting beta-cell adaptation and survival. Rosi might be an appropriate drug for preventing and treating CsA-induced PTDM...
  28. doi request reprint Long-term changes of the prevalence and control rate of hypertension among Korean adults with diagnosed diabetes: 1998-2008 Korean National Health and Nutrition Examination Survey
    Seung Hyun Ko
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Republic of Korea
    Diabetes Res Clin Pract 97:151-7. 2012
    ..We investigated the long-term changes in the prevalence and the control rate of hypertension among Korean adults diagnosed with diabetes...
  29. doi request reprint Serum uric acid level is associated with metabolic syndrome and microalbuminuria in Korean patients with type 2 diabetes mellitus
    Eun Sook Kim
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
    J Diabetes Complications 25:309-13. 2011
    ..To determine the relationship between serum uric acid, metabolic syndrome (MetS), and albuminuria in type 2 diabetic patients...
  30. pmc Prevalence and associated factors of diabetic retinopathy in rural Korea: the Chungju metabolic disease cohort study
    Ji Hyun Kim
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
    J Korean Med Sci 26:1068-73. 2011
    ..This emphasizes that regular screening for diabetic retinopathy and more aggressive management of glycemia can reduce the number of people who develop diabetic retinopathy...
  31. doi request reprint Targeting PGC-1α to overcome the harmful effects of glucocorticoids in porcine neonatal pancreas cell clusters
    Ji Won Kim
    1 Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea 2 Convergent Research Consortium for Immunologic Disease, The Catholic University of Korea, Seoul, Korea 3 Address correspondence to Kun Ho Yoon, MD, PhD, Department of Endocrinology and Metabolism, Seoul St Mary s Hospital, The Catholic University of Korea, 505, Banpo dong, Seocho Gu 137 040, Seoul, Korea
    Transplantation 97:273-9. 2014
    ..However, the molecular mechanism has not been clarified...
  32. doi request reprint Altered calcium homeostasis is correlated with the presence of metabolic syndrome and diabetes in middle-aged and elderly Korean subjects: the Chungju Metabolic Disease Cohort study (CMC study)
    Mee Kyoung Kim
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Atherosclerosis 212:674-81. 2010
    ..To clarify the association of serum calcium level with metabolic syndrome (MetS) and diabetes in middle-aged and elderly Korean subjects...
  33. ncbi request reprint Prospective study of lipoprotein(a) as a risk factor for deteriorating renal function in type 2 diabetic patients with overt proteinuria
    Ki Ho Song
    Department of Internal Medicine, Catholic University of Korea, Seoul, Korea
    Diabetes Care 28:1718-23. 2005
    ..The aim of this study was to determine whether Lp(a) is an independent risk factor for deteriorating renal function in type 2 diabetic patients with nephropathy...
  34. pmc Diabetic peripheral neuropathy is associated with increased arterial stiffness without changes in carotid intima-media thickness in type 2 diabetes
    Eun Sook Kim
    Division of Endocrinology, Department of Internal Medicine, Incheon St Mary s Hospital, The Catholic University of Korea, Incheon, Korea
    Diabetes Care 34:1403-5. 2011
    ..This study was conducted to investigate the association of diabetic peripheral neuropathy (DPN) with both arterial stiffness and intima-media thickness (IMT)...
  35. ncbi request reprint Glucocorticoid treatment independently affects expansion and transdifferentiation of porcine neonatal pancreas cell clusters
    Ji Won Kim
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    BMB Rep 45:51-6. 2012
    ..PGC-1α plays an important role in the expansion and transdifferentiation of porcine NPCCs, and the initial 2 weeks following transplantation of porcine NPCCs is a critical period in determining the final β-cell mass in grafts...
  36. doi request reprint Usefulness of albuminuria as predictor for coronary artery stenosis, regardless of estimated glomerular filtration rate, in patients with type 2 diabetes mellitus
    Jang Won Son
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic University of Korea, Bucheon St Mary s Hospital, Bucheon, Korea
    Am J Cardiol 110:1434-9. 2012
    ..710 with carotid IMT plus ACR, p = 0.0144). In conclusion, the presence of albuminuria is an independent predictor for significant coronary stenosis in patients with type 2 DM and subclinical atherosclerosis...
  37. doi request reprint Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells
    Gyeong Ryul Ryu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 439:258-63. 2013
    ..In conclusion, we demonstrated that high glucose increased oxidative stress in primary rat PSCs, thereby facilitating the activation of these cells, while antioxidant treatment attenuated high glucose-induced PSC activation...
  38. ncbi request reprint Loss of beta-cells with fibrotic islet destruction in type 2 diabetes mellitus
    Ji Won Kim
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    Front Biosci 13:6022-33. 2008
    ....
  39. ncbi request reprint In vitro transdifferentiation of adult pancreatic acinar cells into insulin-expressing cells
    Ki Ho Song
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 316:1094-100. 2004
    ..This study provides the first evidence that adult pancreatic acinar cells could be differentiated into insulin-expressing cells in vitro...
  40. doi request reprint Antioxidant treatment may protect pancreatic beta cells through the attenuation of islet fibrosis in an animal model of type 2 diabetes
    Esder Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 414:397-402. 2011
    ..Our data suggest that antioxidants may protect beta cells through the attenuation of both islet fibrosis and beta cell apoptosis in type 2 diabetes...
  41. doi request reprint Serum BMP-4 levels in relation to arterial stiffness and carotid atherosclerosis in patients with Type 2 diabetes
    Jang Won Son
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Bucheon St Mary s Hospital, Bucheon, Republic of Korea
    Biomark Med 5:827-35. 2011
    ..The aim of this study was to evaluate the association between the circulating BMP-4 levels and atherosclerosis in patients with Type 2 diabetes...
  42. pmc Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes
    Mee Kyoung Kim
    Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
    Korean J Intern Med 24:227-32. 2009
    ..Thiazolidinediones reduce urinary albumin excretion and may prevent the development of renal injury. We evaluated the long-term effects of rosiglitazone on the progression of renal dysfunction in patients with type 2 diabetes mellitus...
  43. pmc Generation of functional insulin-producing cells from neonatal porcine liver-derived cells by PDX1/VP16, BETA2/NeuroD and MafA
    Dong Sik Ham
    Department of Endocrinology and Metabolism, College of Medicine, The Catholic University of Korea, Seoul, Korea Seoul St Mary s Hospital Convergent Research Consortium for Immunologic Disease, Seoul, Korea
    PLoS ONE 8:e79076. 2013
    ....
  44. pmc Optimal waist circumference cutoff value reflecting insulin resistance as a diagnostic criterion of metabolic syndrome in a nondiabetic Korean population aged 40 years and over: the Chungju Metabolic Disease Cohort (CMC) study
    Yong Moon Park
    Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seocho Gu, Seoul 137 701, Korea
    Yonsei Med J 51:511-8. 2010
    ..We aimed at determining the cutoff value of waist circumference with respect to its ability to reflect insulin resistance in a Korean population...
  45. ncbi request reprint Transcriptional mechanism of suppression of insulin gene expression by AMP-activated protein kinase activator 5-amino-4-imidazolecarboxamide riboside (AICAR) in beta-cells
    Ji Won Kim
    Department of Endocrinology and Metabolism, The Catholic University of Korea, 505, Ban po Dong, Seocho Gu, Seoul 137 090, Republic of Korea
    Biochem Biophys Res Commun 365:614-20. 2008
    ..Therefore, AMPK may function as a key molecule, which conveys extracellular metabolic signals into the cells and finely tunes expression of beta-cell specific transcription factors in response to glucose level...
  46. ncbi request reprint Suppression of peroxisome proliferator-activated receptor gamma-coactivator-1alpha normalizes the glucolipotoxicity-induced decreased BETA2/NeuroD gene transcription and improved glucose tolerance in diabetic rats
    Ji Won Kim
    Department of Internal Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, Seoul 137 040, Korea
    Endocrinology 150:4074-83. 2009
    ....
  47. doi request reprint Effects on diabetes management of a health-care provider mediated, remote coaching system via a PDA-type glucometer and the Internet
    Jae Hyoung Cho
    Department of Endocrinology and Metabolism, College of Medicine, Catholic University of Korea, Seoul, Korea
    J Telemed Telecare 17:365-70. 2011
    ..The new system could be implemented widely and would contribute to improving the quality of diabetes care, even in isolated rural areas...
  48. doi request reprint Transforming growth factor-β induces epithelial to mesenchymal transition and suppresses the proliferation and transdifferentiation of cultured human pancreatic duct cells
    Jeong Ah Shin
    Department of Endocrinology and Metabolism, The Catholic University of Korea, Seoul, Korea
    J Cell Biochem 112:179-88. 2011
    ..Our results are the first report of TGF-β1 effects for EMT and ductal cell transdifferentiation and proliferation at the protein level in human pancreatic duct cells...
  49. ncbi request reprint The relationship between thyroid nodules and uterine fibroids
    Min Hee Kim
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St Mary s Hospital, The Catholic University of Korea, College of Medicine, Seocho Gu, Seoul, Korea
    Endocr J 57:615-21. 2010
    ..Our study suggested that uterine fibroids in women were definitely associated with thyroid nodules and estrogen might have a pivotal role in occurrence of both uterine fibroids and thyroid nodules...
  50. pmc Progression of cardiovascular autonomic dysfunction in patients with type 2 diabetes: a 7-year follow-up study
    Seung Hyun Ko
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    Diabetes Care 31:1832-6. 2008
    ..We investigated whether cardiovascular autonomic dysfunction was associated with glycemic control status over time in patients with type 2 diabetes...
  51. doi request reprint Factors associated with control of blood pressure among elderly people diagnosed with hypertension in a rural area of South Korea: the Chungju Metabolic Disease Cohort Study (CMC study)
    Hong Seok Lee
    Seoul St Mary s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Blood Press 19:31-9. 2010
    ..This study aimed to investigate the factors associated with control of hypertension in elderly people (>or=60 years old) diagnosed with hypertension...
  52. doi request reprint Incretin secretion is not restored by short-term strict glycaemic control in Korean hyperglycaemic patients with type 2 diabetes
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, St Vincent s Hospital, 93 6, Ji dong, Paldal Gu, Suwon 442 723, Republic of Korea
    Diabetes Res Clin Pract 92:74-81. 2011
    ..To determine whether short-term strict glycaemic control could restore incretin secretion in type 2 diabetic patients. The factors associated with incretin levels were also investigated...
  53. pmc Prevalence and clinical characteristics of the metabolic syndrome in middle-aged Korean adults
    Hyuk Sang Kwon
    Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul
    Korean J Intern Med 20:310-6. 2005
    ..The aim of this study was to analyze the prevalence and clinical characteristic of the metabolic syndrome of adults, over 40 years old, living in Korea...
  54. pmc Exercise treadmill test in detecting asymptomatic coronary artery disease in type 2 diabetes mellitus
    Mee Kyoung Kim
    Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea
    Diabetes Metab J 35:34-40. 2011
    ..The present study was designed to develop criteria for screening patients with type 2 diabetes mellitus (T2DM) for asymptomatic coronary artery disease (CAD)...
  55. doi request reprint Effects of pravastatin on serum adiponectin levels in female patients with type 2 diabetes mellitus
    Ji Hyun Kim
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Atherosclerosis 227:355-9. 2013
    ..This study aimed to evaluate whether pravastatin increase serum total and high molecular weight adiponectin levels and improve insulin sensitivity in female patients with type 2 diabetes mellitus and hypercholesterolemia...
  56. pmc Predicting the development of diabetes using the product of triglycerides and glucose: the Chungju Metabolic Disease Cohort (CMC) study
    Seung Hwan Lee
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St Mary s Hospital, Seoul, Korea
    PLoS ONE 9:e90430. 2014
    ..To determine whether the TyG index, a product of the levels of triglycerides and fasting plasma glucose (FPG) might be a valuable marker for predicting future diabetes...
  57. ncbi request reprint Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats
    Byung Ha Chung
    Xenotransplantation Center, Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea
    Am J Transplant 5:1856-67. 2005
    ..These data suggest that RGTZ has a protective effect against CsA-induced pancreatic and renal injury...
  58. doi request reprint Impact of common type 2 diabetes risk gene variants on future type 2 diabetes in the non-diabetic population in Korea
    Se Eun Park
    Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Hum Genet 57:265-8. 2012
    ..The genetic variations in KCNQ1 are associated with future development of T2DM in Koreans, which might be mediated by differences in insulin secretory function...
  59. doi request reprint Potentiation of the early-phase insulin response by a prior meal contributes to the second-meal phenomenon in type 2 diabetes
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, St Vincent s Hospital, Suwon, Korea
    Am J Physiol Endocrinol Metab 301:E984-90. 2011
    ..679, P = 0.0003). The second-meal phenomenon was evident in patients with type 2 diabetes. Potentiation of the early-phase insulin response by a prior meal contributes to this phenomenon in type 2 diabetes...
  60. pmc Factors Associated with Insulin Resistance in a Middle-Aged Non-Obese Rural Population: The Chungju Metabolic Disease Cohort (CMC) Study
    Sun Young Lim
    Graduate School of Public Health, The Catholic University of Korea, Seoul, Korea
    Epidemiol Health 33:e2011009. 2011
    ..We aimed to determine the characteristics affecting insulin resistance in non-obese middle-aged adults in a rural community...
  61. pmc Predictive clinical parameters and glycemic efficacy of vildagliptin treatment in korean subjects with type 2 diabetes
    Jin Sun Chang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St Mary s Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
    Diabetes Metab J 37:72-80. 2013
    ..The aims of this study are to investigate the glycemic efficacy and predictive parameters of vildagliptin therapy in Korean subjects with type 2 diabetes...
  62. ncbi request reprint A short message service by cellular phone in type 2 diabetic patients for 12 months
    Kun Ho Yoon
    Department of Internal Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul 137 701, Republic of Korea
    Diabetes Res Clin Pract 79:256-61. 2008
    ..Investigate the effectiveness of an educational intervention that used both the cellular phone with a short messaging service (SMS) and the Internet on the glycemic control of the patients with type 2 diabetes mellitus...
  63. ncbi request reprint A patient with combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2
    Seung Hwan Lee
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea
    Gynecol Endocrinol 23:252-6. 2007
    ..Potential mechanisms for their interrelation and the possibility that PCOS is an autoimmune disease are discussed...
  64. ncbi request reprint Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia
    Dong Jun Lim
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137 701, Korea
    Endocr J 54:537-41. 2007
    ..When evaluating acromegaly in type 2 diabetes under poorly controlled glycemia, cautious IGF-1 analysis is needed after sufficient glycemic control...
  65. doi request reprint Prevention of diabetes: a strategic approach for individual patients
    Jeong Ah Shin
    Department of Endocrinology and Metabolism, Seoul St Mary s Hospital, The Catholic University of Korea School of Medicine, Seoul, Korea
    Diabetes Metab Res Rev 28:79-84. 2012
    ..In this review, we will summarize the known evidence on treatment- and cost-effectiveness of drug and lifestyle treatment. Additionally, we will propose a strategic approach algorithm that is applicable to clinical practice...
  66. doi request reprint Novel culture technique involving an histone deacetylase inhibitor reduces the marginal islet mass to correct streptozotocin-induced diabetes
    Jun Seop Shin
    Korea Islet Transplantation Institute, Inc, Seoul, Korea
    Cell Transplant 20:1321-32. 2011
    ....
  67. doi request reprint Diabetic retinopathy is associated with subclinical atherosclerosis in newly diagnosed type 2 diabetes mellitus
    Jang Won Son
    Division of Endocrinology and Metabolism, Department of Internal Medicine, St Mary s Hospital, The Catholic University of Korea, 62, Yeoido dong, Yeoung deungpo gu, Seoul 150 713, Republic of Korea
    Diabetes Res Clin Pract 91:253-9. 2011
    ..We aimed to evaluate the association between diabetic microangiopathy and subclinical atherosclerosis as a marker of cardiovascular disease (CVD) risk in patients with newly diagnosed type 2 diabetes...
  68. ncbi request reprint Adrenal tuberculosis in Cushing's disease with bilateral macronodular adrenocortical hyperplasia
    Hyuk Sang Kwon
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea
    Endocr J 53:219-23. 2006
    ..In summary, to the best of our knowledge, this is the first case of Cushing's disease coexisting with both adrenal tuberculosis simulating a bilateral MNH...
  69. ncbi request reprint Inducible nitric oxide synthase-nitric oxide plays an important role in acute and severe hypoxic injury to pancreatic beta cells
    Seung Hyun Ko
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    Transplantation 85:323-30. 2008
    ..The aim of the present study was to investigate whether acute and severe hypoxic injury could involve inducible nitric oxide synthase (iNOS)-nitric oxide (NO) signaling in beta cells...
  70. doi request reprint Clinical characteristics of Korean patients with new-onset diabetes presenting with diabetic ketoacidosis
    Mee Kyoung Kim
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Diabetes Res Clin Pract 85:e8-11. 2009
    ..Ketosis-prone type 2 diabetes was common (42%) among this group of Korean patients with new-onset diabetes presenting with diabetic ketoacidosis. These patients were younger, showed a greater defect in insulin secretion...
  71. ncbi request reprint Mobile communication using a mobile phone with a glucometer for glucose control in Type 2 patients with diabetes: as effective as an Internet-based glucose monitoring system
    Jae Hyoung Cho
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul, Korea
    J Telemed Telecare 15:77-82. 2009
    ....
  72. ncbi request reprint The association of serum vitamin D level with presence of metabolic syndrome and hypertension in middle-aged Korean subjects
    Mee K Kim
    Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea
    Clin Endocrinol (Oxf) 73:330-8. 2010
    ..To examine the association of serum vitamin D level with metabolic syndrome (MetS) and hypertension (HTN) in middle-aged Korean subjects...
  73. ncbi request reprint A telephone-delivered intervention to improve glycemic control in type 2 diabetic patients
    Jeong Ah Oh
    College of Nursing, The Catholic University of Korea, 505 Banpo Dong, Secho gu, Seoul 137 701, Korea
    Yonsei Med J 44:1-8. 2003
    ..6%, in HbA1c. There were no significant differences in the body mass index (BMI) between the two groups. These findings indicated that a telephone-delivered intervention would improve HbA1c, but would not affect BMI...
  74. pmc Comparison of the efficacy of glimepiride, metformin, and rosiglitazone monotherapy in korean drug-naïve type 2 diabetic patients: the practical evidence of antidiabetic monotherapy study
    Kun Ho Yoon
    Department of Endocrinology, The Catholic University of Korea School of Medicine, Seoul, Korea
    Diabetes Metab J 35:26-33. 2011
    ..Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be clearly demonstrated...
  75. doi request reprint Effects of rosiglitazone on body fat distribution and insulin sensitivity in Korean type 2 diabetes mellitus patients
    You Cheol Hwang
    Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Republic of Korea
    Metabolism 57:479-87. 2008
    ..The RSG treatment improved the glucose control in type 2 diabetes mellitus. However, it is important to determine whether the glucose-lowering effect of RSG occurs mainly through direct enhancement of insulin sensitivity...
  76. pmc Low Density Lipoprotein Cholesterol Target Goal Attainment Rate and Physician Perceptions about Target Goal Achievement in Korean Patients with Diabetes
    Jenie Yoonoo Hwang
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Diabetes Metab J 35:628-36. 2011
    ....
  77. ncbi request reprint Body mass index is the most important determining factor for the degree of insulin resistance in non-obese type 2 diabetic patients in Korea
    Sang Ah Chang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea
    Metabolism 53:142-6. 2004
    ..These results suggest that the BMI is the most important determinant of insulin resistance, while TG and HDL-C levels might be good markers of insulin resistance in non-obese patients with type 2 diabetes mellitus in Korea...
  78. ncbi request reprint False-positive iodine uptake in thymic hyperplasia on diagnostic I-123 whole-body scan after total thyroidectomy
    Seung Hwan Lee
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Clin Nucl Med 32:154-5. 2007
  79. doi request reprint Continuous glucose monitoring: current clinical use
    Hun Sung Kim
    Department of Endocrinology and Metabolism, Seoul St Mary s Hospital, The Catholic University of Korea, Seoul, Korea
    Diabetes Metab Res Rev 28:73-8. 2012
    ..CGM-integrated communication systems using information technology such as smart phone help controlling blood glucose more easily and effectively...
  80. pmc Perception of clinicians and diabetic patients on the importance of postprandial glucose control and diabetes education status: a cross sectional survey
    Ji Hun Choi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Diabetes Metab J 36:120-7. 2012
    ..This study was conducted in order to survey the perceptions of clinicians and diabetic patients with respect to PPG management and the current status of diabetes education...
  81. pmc Effects of a 6-Month Exenatide Therapy on HbA1c and Weight in Korean Patients with Type 2 Diabetes: A Retrospective Cohort Study
    Juyoung Shin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Diabetes Metab J 36:364-70. 2012
    ..Therefore, this retrospective cohort study was designed to analyze the effects of exenatide on blood glucose level and body weight in Korean patients with type 2 diabetes mellitus...
  82. ncbi request reprint Activation of AMP-activated protein kinase mediates acute and severe hypoxic injury to pancreatic beta cells
    Gyeong Ryul Ryu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    Biochem Biophys Res Commun 386:356-62. 2009
    ..These results suggest that AMPK, in association with oxidative stress, plays an important role in acute and severe hypoxic injury to pancreatic beta cells...
  83. pmc Thy1-positive bone marrow stem cells express liver-specific genes in vitro and can mature into hepatocytes in vivo
    Si Hyun Bae
    Department of Internal Medicine, Kangnam St Mary s Hospital, The Catholic University of Korea, 505 Banpo Dong, Seocho Gu, Seoul, 137 701, South Korea
    Hepatol Int 2:63-71. 2008
    ..Thy1-positive bone marrow stem cells may represent preexisting hepatocyte-specific stem cells...
  84. ncbi request reprint Glycated albumin causes pancreatic β-cells dysfunction through autophagy dysfunction
    Young Mi Song
    Brain Korea 21 Project for Medical Science, Seoul 120 752, Korea
    Endocrinology 154:2626-39. 2013
    ....
  85. pmc Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells
    Min Koo Seo
    Research Institute of Immunobiology, Department of Biomedical Sciences, The Catholic University of Korea School of Medicine, Seoul, Korea
    Diabetes Metab J 35:72-9. 2011
    ..In this study, we examined if pancreatic cells transfected repeatedly with pEBVHGF can be successfully grafted to control blood glucose in a diabetes mouse model...
  86. pmc Management of blood pressure in patients with type 2 diabetes mellitus: a nationwide survey in korean
    Mi Hae Seo
    Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Diabetes Metab J 35:348-53. 2011
    ..Hypertension is common in patients with type 2 diabetes, affecting up to 60% of patients. The Korean Diabetes Association performed a nationwide survey about prevalence, awareness and control of hypertension among diabetic Koreans...
  87. pmc Service design attributes affecting diabetic patient preferences of telemedicine in South Korea
    Hayoung Park
    Technology Management, Economics and Policy Graduate Program, Seoul National University, Seoul, Republic of Korea
    Telemed J E Health 17:442-51. 2011
    ..In this study, we explore patients' valuations and preferences for each attribute of telemedicine service for diabetes management and evaluate patient willingness to pay for specific service attributes...
  88. doi request reprint Addressing the burden of type 2 diabetes and cardiovascular disease through the management of postprandial hyperglycaemia: an Asian-Pacific perspective and expert recommendations
    Wayne H H Sheu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    Diabetes Res Clin Pract 92:312-21. 2011
    ..Additionally, frequent meal-based testing and effective PPHG management are essential to the management of IGT and type 2 diabetes...
  89. ncbi request reprint Circulating osteoprotegerin levels are associated with age, waist-to-hip ratio, serum total cholesterol, and low-density lipoprotein cholesterol levels in healthy Korean women
    Eun Sook Oh
    Department of Internal Medicine, Miz Medi Hospital, Seoul, Republic of Korea
    Metabolism 54:49-54. 2005
    ..Out findings suggest that OPG may be an important paracrine factor of cardiovascular disease in the female population...
  90. ncbi request reprint The effect of bone marrow transplantation on the osteoblastic differentiation of human bone marrow stromal cells
    Won Young Lee
    Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Endocrinol Metab 87:329-35. 2002
    ..In conclusion, the differentiation of bone marrow stromal cells into osteoblasts was impaired after BMT, and this might contribute to post-BMT bone loss...
  91. doi request reprint Induction of efficient differentiation and survival of porcine neonatal pancreatic cell clusters using an EBV-based plasmid expressing HGF
    Min Sun Kim
    Research Institute of Immunobiology, Department of Biomedical Sciences, Catholic University of Korea, Seoul, Republic of Korea
    J Biochem 143:497-503. 2008
    ..Therefore, it may be possible to use EBV-based plasmids to modify pancreatic stem cells for xenotransplantation...
  92. ncbi request reprint Assessment of glycemic lability and severity of hypoglycemia in Korean patients with type 1 diabetes
    Soo Kyoung Kim
    Department of Endocrinology and Metabolism, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Endocr J 58:433-40. 2011
    ..The results showed that the hypoglycemic indexes in this study population were lower than the results from Ryan et al. Furthermore, the ADRR or modified LI were better measures for high risk of severe lability than were the LI and MAGE...
  93. ncbi request reprint Long-term treatment with ramipril attenuates renal osteopontin expression in diabetic rats
    Can Li
    Department of Internal Medicine and Anatomy, The Catholic University of Korea, Seoul, Korea
    Kidney Int 63:454-63. 2003
    ....
  94. ncbi request reprint A Novel IVS2-1G>A mutation causes aberrant splicing of the HRPT2 gene in a family with hyperparathyroidism-jaw tumor syndrome
    Sung Dae Moon
    Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul 137 701, Korea
    J Clin Endocrinol Metab 90:878-83. 2005
    ..These findings provide further evidence that mutation of HRPT2 is associated with the formation of parathyroid tumors in HPT-JT syndrome...
  95. ncbi request reprint Role of metformin in the initiation of pharmacotherapy for type 2 diabetes: an Asian-Pacific perspective
    Juliana C N Chan
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hongkong
    Diabetes Res Clin Pract 75:255-66. 2007
    ..These recommendations can serve as templates for development of local guidelines for Asian people with diabetes, given the ethnic and cultural diversity within the region...
  96. ncbi request reprint IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo
    Seung Eun Choi
    Department of Biochemistry, College of Medicine, Seoul National University, 28 Yongon dong Chongno gu, Seoul 110 799, South Korea
    Transpl Immunol 13:43-53. 2004
    ..This strategy could be exploited in the clinical setting to maintain functional islet mass...
  97. ncbi request reprint Development and retroviral transduction of porcine neonatal pancreatic islet cells in monolayer culture
    Krystyna Tatarkiewicz
    Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA
    Dev Growth Differ 45:39-50. 2003
    ..Furthermore, in such a culture setting, precursor duct cells have a high rate of proliferation and are more efficiently transduced with a retrovirus-based reporter gene than are beta cells...