Research Topics
Genomes and GenesSpecies | Yeon Joon ParkSummaryAffiliation: The Catholic University of Korea Country: Korea Publications
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Publications
Evaluation of Phoenix Automated Microbiology System for detecting extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii, and Serratia marcescensYeon Joon Park
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul 137 701, Korea
Ann Clin Lab Sci 37:75-8. 2007..8%). Considering the increasing prevalence of ESBL production among AmpC-producers, the BD Phoenix system could not be considered a reliable stand-alone ESBL detection method for the strains tested in our study...
Accumulation of plasmid-mediated fluoroquinolone resistance genes, qepA and qnrS1, in Enterobacter aerogenes co-producing RmtB and class A beta-lactamase LAP-1Yeon Joon Park
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Ann Clin Lab Sci 39:55-9. 2009....
Prevalence and diversity of qnr alleles in AmpC-producing Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii and Serratia marcescens: a multicentre study from KoreaYeon Joon Park
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul 137 701, Korea
J Antimicrob Chemother 60:868-71. 2007..To investigate the prevalence of qnr determinants, their influence on quinolone susceptibility and their association with other plasmid-mediated genes in AmpC-producing Enterobacteriaceae without any selection criteria...
Spread of Serratia marcescens coharboring aac(6')-Ib-cr, bla CTX-M, armA, and bla OXA-1 carried by conjugative IncL/M type plasmid in Korean hospitalsYeon Joon Park
Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea
Microb Drug Resist 15:97-102. 2009..Stringent infection control practices and further investigation of association between mobile elements and resistance genes are warranted...
Occurrence of extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteriaYeon Joon Park
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, Seoul 137 040, Korea
Diagn Microbiol Infect Dis 51:265-9. 2005..The FEP MIC > or = 1 microg/mL had the highest sensitivity (95.3%), specificity (82.7%), and positive (65.8%) and negative predictive values (98.3%)...
Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coliYeon Joon Park
Department of Laboratory Medicine, School of Medicine, The Catholic University of Korea, 505 Banpo Dong, Seocho Ku, Seoul, 137 701, South Korea
Diagn Microbiol Infect Dis 71:87-9. 2011..The presence of bla(CTX-M-14) and loss of OmpK36 were associated with higher carbapenem MICs...
Prevalence and mechanisms of decreased susceptibility to carbapenems in Klebsiella pneumoniae isolatesSoo Young Kim
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, St Vincent s Hospital, Suwon 442 723, South Korea
Diagn Microbiol Infect Dis 57:85-91. 2007..pneumoniae when bla(GES-3), bla(TEM-11), bla(SHV-12), bla(OXA-17), and/or bla(DHA-1) are produced in combination with porin loss. In addition, to our knowledge, this is the 1st report of bla(OXA-17) in Enterobacteriaceae...
Prevalence and characteristics of aac(6')-Ib-cr in AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens: a multicenter study from KoreaSoo Young Kim
Department of Laboratory Medicine, The Catholic University of Korea, St Vincent s Hospital, Paldal Gu, Suwon, South Korea
Diagn Microbiol Infect Dis 63:314-8. 2009..Although aac(6')-Ib-cr was uncommon in Korean AmpC producers, its association with various resistance genes and mobile elements would facilitate the dissemination of this variant...
Comparison of protocols for surveillance of methicillin-resistant Staphylococcus aureus (MRSA): medical staff vs ICU patientsSeungok Lee
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul, Korea
Ann Clin Lab Sci 37:248-50. 2007..1% on D-BAP vs 96.2% on B-BAP). The simple direct plating protocol was sufficiently sensitive for the medical staff members, but pre-enrichment was an essential step to increase detection of MRSA in the ICU patients...
Evaluation of phenotypic screening methods for detecting plasmid-mediated AmpC beta-lactamases-producing isolates of Escherichia coli and Klebsiella pneumoniaeKyungwon Lee
Department of Laboratory Medicine, Yonsei University Hospital, Seoul 120-752, South Korea
Diagn Microbiol Infect Dis 53:319-23. 2005..6% of bla(DHA-1) allele-positive isolates. These phenotypic tests should be useful to screen P-M AmpC beta-lactamase-producing E. coli and K. pneumoniae isolates...
Occurrence and mechanisms of amikacin resistance and its association with beta-lactamases in Pseudomonas aeruginosa: a Korean nationwide studyJa Young Kim
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
J Antimicrob Chemother 62:479-83. 2008..We investigated the occurrence and mechanism of amikacin resistance and its association with various beta-lactamase genes in Pseudomonas aeruginosa isolates...
Evaluation of Vitek2 and BD Phoenix in antimicrobial susceptibility testing of Acinetobacter baumannii and Pseudomonas aeruginosaDong Wook Jekarl
Department of Laboratory Medicine, College of Medicine, Seoul St Mary s Hospital, The Catholic University of Korea, Seoul, 137 701, Republic of Korea
Diagn Microbiol Infect Dis 67:384-6. 2010..Both systems showed overall categoric agreement of < or =90% for cefepime and ceftazidime against A. baumannii and imipenem and cefepime (and ceftazidime with Vitek2) against P. aeruginosa because of high minor error rates...
Donor-specific HLA class I and CREG antibodies in complement-dependent cytotoxicity-negative renal transplantsYonggoo Kim
Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea
Ann Clin Lab Sci 40:330-5. 2010..001). This study demonstrates that detection of DSA, including DS-HLA and DS-CREG, using the SA-PRA assay is useful to identify the renal allograft recipients with poor transplant outcome...
Molecular analysis of isoniazid resistance in Mycobacterium tuberculosis isolates recovered from South KoreaSoo Young Kim
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, St Vincent s Hospital, 93 Chi dong, 442 723, Paldal Ku, Suwon, South Korea
Diagn Microbiol Infect Dis 47:497-502. 2003..The sensitivity and specificity of molecular analysis of the katG codon 315 and/or the inhA promoter region were 80.3 and 100%, respectively. Therefore, mutations in these regions are highly predictive of INH resistance in South Korea...
Further increases in carbapenem-, amikacin-, and fluoroquinolone-resistant isolates of Acinetobacter spp. and P. aeruginosa in Korea: KONSAR study 2009Kyungwon Lee
Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea
Yonsei Med J 52:793-802. 2011..The aim of this study was to analyze antimicrobial resistance data generated in 2009 by hospitals and commercial laboratories participating in the Korean Nationwide Surveillance of Antimicrobial Resistance program...
Aminoglycoside susceptibility profiles of Enterobacter cloacae isolates harboring the aac(6')-Ib geneSoo Young Kim
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, St Vincent s Hospital, Suwon, Korea
Korean J Lab Med 31:279-81. 2011....
False susceptibility to amikacin by VITEK 2 in Acinetobacter baumannii harboring armASunkyung Jung
Laboratory Medicine Department, St Mary s Hospital, The Catholic University of Korea, Seoul, Korea
Ann Clin Lab Sci 40:167-71. 2010..baumannii isolate harboring armA. This phenomenon was not observed in the Serratia marcescens isolate harboring armA, but was detected in its transconjugant E. coli J53...
Risk factors for mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia: impact of appropriate antimicrobial therapyYoun Jeong Kim
Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
J Korean Med Sci 27:471-5. 2012..05, 95% CI 1.65-39.2; P = 0.009) were independent risk factors for 14-day mortality. Early definite antimicrobial therapy had an influence on favorable outcomes in patients with A. baumannii bacteremia...
Comparative quantitative analysis of cluster of differentiation 45 antigen expression on lymphocyte subsetsMijeong Im
Department of Laboratory Medicine, Graduate School, The Catholic University of Korea, College of Medicine, Seoul, Korea
Korean J Lab Med 31:148-53. 2011..Here, we analyzed CD45 expression on lymphocyte subsets using flow cytometry in order to predict the susceptibility of normal lymphocytes to RIT...
Correction of Pseudoreticulocytosis in Leukocytosis Samples Using the Sysmex XE-2100 Analyzer Depends on the Type and Number of White Blood CellsAhhyun Kim
Department of Laboratory Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
Ann Lab Med 32:392-8. 2012..In this study, we analyzed reticulocyte counts in leukocytosis samples, in an effort to identify a correction method...
Application of calculated panel reactive antibody using HLA frequencies in KoreansJi Young Jang
Department of Laboratory Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea
Ann Lab Med 32:66-72. 2012..We developed a CPRA calculator based on the HLA frequencies in Koreans to measure sensitization levels in Korean patients...
Comparison of Seeplex VRE detection kit with ChromID VRE agar for detection of vancomycin-resistant enterococci in rectal swab specimensSo Young Lee
Department of Laboratory Medicine, Seoul St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul 137 701, Korea
Ann Clin Lab Sci 40:163-6. 2010..Unexpectedly, 15.7% of VRE were vanA-positive Enterococcus species other than E. faecium and E. faecalis. Vigilance is suggested to see if these species eventually emerge as significant pathogens...
Detection of anti-aquaporin-4 antibodies in neuromyelitis optica: comparison of tissue-based and cell-based indirect immunofluorescence assays and ELISAYoon Joo Kim
Department of Laboratory Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea
J Clin Lab Anal 26:184-9. 2012..01). In summary, we observed an increased prevalence of NMO-IgG in patients with NMO and NMO spectrum disorders. ELISA-AQP4 may be more sensitive and specific when confirmed by IIF-AQP4...
Prevalence of acquired fosfomycin resistance among extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae clinical isolates in Korea and IS26-composite transposon surrounding fosA3So Young Lee
Department of Laboratory Medicine, College of Medicine, Catholic University of Korea, Seoul, Korea
J Antimicrob Chemother 67:2843-7. 2012..To investigate the prevalence of plasmid-mediated fosfomycin resistance determinants among extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae and their genetic environments...
Pretransplant IFN-γ ELISPOT assay as a potential screening test to select immunosuppression protocols for patients receiving basiliximab induction therapyYonggoo Kim
Department of Laboratory Medicine, Seoul St Mary s Hospital, The Catholic University of Korea, Seoul, Korea
Transl Res 160:230-6. 2012..Our results suggest that the pretransplant ELISPOT (+) may assess the risk of poor post-transplant outcomes in patients with basiliximab induction...
Comparative study of immunofluorescent antinuclear antibody test and line immunoassay detecting 15 specific autoantibodies in patients with systemic rheumatic diseaseSun Ah Lee
Department of Laboratory Medicine, School of Medicine, The Catholic University of Korea, 505 Banpo Dong, Seocho Gu, Seoul, South Korea
J Clin Lab Anal 26:307-14. 2012..In patients with clinical suspicion of SRD, screening with both FANA and sp-ANAs tests could improve diagnostic efficiency...
Diagnostic value of Elecsys S100 as a marker of acute brain injury in the emergency departmentEun Jee Oh
Department of Laboratory Medicine, College of Medicine, Catholic University of Korea, Seoul, Korea
J Clin Lab Anal 21:387-92. 2007..478). In conclusion, serum S100 levels can be used in the emergency department as an additional screening tool to identify CCT- or MRI-positive ABI...
[Acute hemolysis and renal failure caused by hepatitis A infection with underlying glucose-6-phosphate dehydrogenase deficiency]Dong Wook Jekarl
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Korean J Lab Med 27:188-91. 2007..Because hepatitis A infection in patient with G6PD deficiency present much more severe clinical symptoms, G6PD enzyme should be examined in patients with triggering factors of hemolysis such as hepatitis A infection...
Phylogenetic groups and virulence factors in pathogenic and commensal strains of Escherichia coli and their association with blaCTX-MSeungok Lee
Dept of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea
Ann Clin Lab Sci 40:361-7. 2010..Considering the possibility that these virulence genes, together with antimicrobial resistance genes, can spread to other strains, further study and ongoing surveillance seem to be required...
Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: a KONSAR study in 2002Kyungwon Lee
Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea
Yonsei Med J 45:598-608. 2004..aeruginosa and Acinetobacter spp. increased gradually, and imipenem- resistant E. coli and K. pneumoniae appeared for the first time. Continued surveillance is required to prevent further spread of these serious resistances...
[Detection of allergen specific IgE by AdvanSure Allergy Screen test]Eun Jee Oh
Department of Laboratory Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea
Korean J Lab Med 30:420-31. 2010..We evaluated the clinical usefulness of a newly introduced multiple antigen screen test, Advansure Allergy Screen (LG Life Science, Korea) (LG-Screen) for the detection of allergen specific IgE...
Risk factors for vancomycin-resistant enterococci infection and mortality in colonized patients on intensive care unit admissionYoun Jeong Kim
Division of Infectious Disease, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea Infection Control Department, Seoul St Mary s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Am J Infect Control 40:1018-9. 2012..6%) in whom VRE perianal swab cultures were obtained. Of these, 28 (11.9%) developed VRE infection. Control of infectious sources is crucial to decrease development of VRE infections and optimize the survival of VRE-colonized patients...
Predictive value of interferon-γ ELISPOT assay in HIV 1-infected patients in an intermediate tuberculosis-endemic areaYoun Jeong Kim
Division of Infectious Diseases, Department of Internal Medicine, Seoul St Mary s Hospital, The Catholic University of Korea, Republic of Korea
AIDS Res Hum Retroviruses 28:1038-43. 2012..Advanced HIV-infected patients who showed a positive TB ELISPOT assay had a higher rate of progression to TB in the intermediate TB-endemic area...
Differential blast counts obtained by automated blood cell analyzersSeungwon Jung
Department of Laboratory Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
Korean J Lab Med 30:540-6. 2010..Automated blood cell analyzers often read leukemic blasts as normal cells. In this study, we evaluated the 5-part differential patterns of blasts using automated analyzers to determine if they can differentiate among blast types...
Reliable, accurate determination of the leukocyte differential of leukopenic samples by using Hematoflow methodYongjun Jo
Department of Laboratory Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
Korean J Lab Med 31:131-7. 2011..We evaluated the efficacy of the Hematoflow method for determining the leukocyte differential in leukopenic samples and compared this method with the manual differential method...
Comparison of the Abbott Architect i2000 assay, the Roche Modular Analytics E170 assay, and an immunoradiometric assay for serum hepatitis B virus markersHyunjung Kim
Department of Laboratory Medicine, The Catholic University of Korea, Kangnam St Mary s Hospital, 505 Banpo Dong, Seocho Ku, Seoul, South Korea
Ann Clin Lab Sci 37:256-9. 2007..9%) followed by the IRMA kit (54.1%) and Architect i2000 (51.0%). This study shows substantial differences between the assay results by the three methods, which should be taken into account in determinations of serum HBV markers...
[Performance evaluation of BD GeneOhm MRSA PCR assay for detection of nasal colonization of methicillin-resistant Staphylococcus aureus at endemic intensive care units]Sang Hyuk Park
Department of Laboratory Medicine, University of Ulsan College of Medicine, Seoul, Korea
Korean J Lab Med 29:439-47. 2009..We evaluated the performance of BD GeneOhm MRSA PCR assay versus MRSASelect (Bio-Rad, France) and broth enrichment cultures for detection of MRSA from nasal swabs...
Comparison of the Bactec Fx Plus, Mycosis IC/F, Mycosis/F Lytic Blood Culture Media and the BacT/Alert 3D FA Media for Detection of Candida species in Seeded Blood Culture Specimens Containing Therapeutic Peak Levels of FluconazoleDong Wook Jekarl
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
J Clin Lab Anal 26:412-9. 2012..The performance of Bactec Fx Plus Aerobic/F (PA), Mycosis IC/F (MF), Myco/F Lytic (ML) media and BacT/Alert 3D FA (FA) media in detecting 15 Candida isolates in blood cultures to which fluconazole had been added was investigated...
Severe hemolytic disease of the newborn due to anti-Di b treated with phototherapy and intravenous immunoglobulinEun Jee Oh
Department of Laboratory Medicine, College of Medicine, Catholic University of Korea, 505 Banpo dong Seocho ku, Seoul, 137 040, South Korea
Ann Clin Lab Sci 38:80-2. 2008..Since most commercial antibody detection panels do not contain Di(b-) red cells, it is important to consider anti-Di(b) in cases of hemolytic disease of the newborn caused by an antibody against a high frequency antigen...
[Comparative evaluation of ELISA and Luminex panel reactive antibody assays for HLA alloantibody screening]Seonkyung Jung
Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea
Korean J Lab Med 29:473-80. 2009..In this study, we analyzed the panel reactive antibody (PRA) test results using ELISA and Luminex methods, and the results were compared with those of crossmatch test...
[Detection of platelet specific antibodies by modified antigen capture ELISA test.]Hyunjong Kim
Department of Laboratory Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea
Korean J Lab Med 26:192-7. 2006..The aim of this study was to evaluate the clinical usefulness of a Modified Antigen Capture Enzyme-linked immunosorbent assay (MACE) test in the diagnosis of AITP...
[Evaluation of Anti-dsDNA antibody tests: Crithidia luciliae immunofluorescence test, immunoblot, enzyme-linked immunosorbent assay, chemiluminescence immunoassay]Jin Young Yang
Department of Laboratory Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea
Korean J Lab Med 30:675-84. 2010..Although several methods are available, none of them is completely satisfactory and differences among them have been reported. We evaluated the diagnostic performance of 6 commercial kits for anti-dsDNA detection...
[Molecular analysis of two cases of severe congenital neutropenia]Joonhong Park
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Korean J Lab Med 30:111-6. 2010..But the patient B showed a partial response to G-CSF treatment and experienced several episodes of herpetic gingivostomatitis, oral ulcer, acute pharyngotonsillitis and otitis media during follow-up...
Comparison of culture screening protocols for methicillin-resistant Staphylococcus aureus (MRSA) using a chromogenic agar (MRSA-Select)Seungok Lee
Department of Laboratory Medicine, College of Medicine, Catholic University of Korea, Holy Family Hospital, Pucheon, Korea
Ann Clin Lab Sci 38:254-7. 2008..Salt-containing enrichment broth in conjunction with MRSA-Select (B-MRSA-Select) provides a promising way to increase sensitivity in initial and follow-up screening for MRSA...
Successful treatment of septic shock with purpura fulminans caused by Trichosporon asahii in an immunocompetent patientYoun Jeong Kim
Department of Internal Medicine, Kangnam St Mary s Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea
Ann Clin Lab Sci 37:366-9. 2007..We report a 46-yr-old man who had been healthy and who presented with septic shock and purpura fulminans caused by Trichosporon asahii. He responded well to antifungal therapy with amphotericin B and voriconazole...
MDCT abnormalities of small- and medium-sized bronchus in active tuberculosis: a new angle on an old diseaseJin Kyoung Oh
Department of Radiology, Seoul St Mary s Hospital, The Catholic University of Korea, Korea
Acta Radiol 52:167-72. 2011..Purpose To evaluate the prevalence and findings of MDCT abnormalities of small- and medium-sized bronchus (SMB) in active pulmonary tuberculosis (TB)...
