Myungshin Kim


Affiliation: The Catholic University of Korea
Country: Korea


  1. Jang W, Kim J, Chae H, Kim M, Koh K, Park C, et al. Hereditary spherocytosis caused by copy number variation in SPTB gene identified through targeted next-generation sequencing. Int J Hematol. 2019;: pubmed publisher
    ..In addition, chromosomal microarray may be useful in defining combined deleted genes. Additional evaluations should thus be considered in the diagnosis of HS, especially when CNV is revealed as disease-causing abnormality. ..
  2. Jang W, Park J, Kwon A, Choi H, Kim J, Lee G, et al. CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia. Exp Mol Med. 2019;51:4 pubmed publisher
    ..Different susceptible genetic backgrounds exist based on the CDKN2B downregulation mechanism. ..
  3. Jo I, Chung N, Lee S, Kwon A, Kim J, Choi H, et al. Considerations for monitoring minimal residual disease using immunoglobulin clonality in patients with precursor B-cell lymphoblastic leukemia. Clin Chim Acta. 2019;488:81-89 pubmed publisher
    ..The Ig clonality assay via HTS will be a promising tool for MRD monitoring of B-ALL through an adequate strategy to identify and monitor individual clones and determine repertoire diversity. ..
  4. Kim Y, Jekarl D, Kim J, Kwon A, Choi H, Lee S, et al. Genetic and epigenetic alterations of bone marrow stromal cells in myelodysplastic syndrome and acute myeloid leukemia patients. Stem Cell Res. 2015;14:177-84 pubmed publisher
    ..9±3.8, 69.4±4.2, respectively). These findings seem worthy of further evaluation of their association with ineffective hematopoiesis and leukemogenesis. ..
  5. Lee S, Park B, Kim J, Jekarl D, Choi H, Lee S, et al. The effect of fibroblast growth factor on distinct differentiation potential of cord blood-derived unrestricted somatic stem cells and Wharton's jelly-derived mesenchymal stem/stromal cells. Cytotherapy. 2015;17:1723-31 pubmed publisher
    ..bFGF supplementation improved the growth capacity and adipogenic differentiation of CB-USSCs. ..
  6. Chae H, Han E, Yoo J, Lee J, Lee J, Cha K, et al. Heavy/light chain assay as a biomarker for diagnosis and follow-up of multiple myeloma. Clin Chim Acta. 2018;479:7-13 pubmed publisher
  7. Kim J, Kim Y, Choi H, Kwon A, Jekarl D, Lee S, et al. Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells. Cell Death Dis. 2018;9:139 pubmed publisher
    ..These results indicate that the decrement of UBC expression plays a pivotal role in replicative senescence of hBM-MSCs. ..
  8. Chae H, Cho S, Yu H, Cha K, Lee S, Kim M, et al. Determination of posaconazole concentration with LC-MS/MS in adult patients with hematologic malignancy. Clin Chim Acta. 2015;450:220-6 pubmed publisher
    ..0063) were significantly associated with higher and lower posaconazole concentrations, respectively. TDM of posaconazole oral suspension formulation is recommended based on the exposure-response relationship of the present study. ..
  9. Han E, Kim M, Kim Y, Han K, Lim J, Kang D, et al. Practical informativeness of short tandem repeat loci for chimerism analysis in hematopoietic stem cell transplantation. Clin Chim Acta. 2017;468:51-59 pubmed publisher

More Information


  1. Jeong C, Lee J, Kim J, Chae H, Park H, Kim M, et al. Novel COL9A3 mutation in a family diagnosed with multiple epiphyseal dysplasia: a case report. BMC Musculoskelet Disord. 2014;15:371 pubmed publisher
  2. Chae H, Kim J, Lee G, Jang W, Park J, Jekarl D, et al. Considerations when using next-generation sequencing for genetic diagnosis of long-QT syndrome in the clinical testing laboratory. Clin Chim Acta. 2017;464:128-135 pubmed publisher
    ..We developed and validated this robust, high-throughput NGS test and informatics pipeline for LQTS diagnosis suitable for the clinical testing laboratory. ..
  3. Park J, Song M, Jang W, Chae H, Lee G, Kim K, et al. Peptide nucleic acid probe-based fluorescence melting curve analysis for rapid screening of common JAK2, MPL, and CALR mutations. Clin Chim Acta. 2017;465:82-90 pubmed publisher
    ..PNA-based FMCA for detecting common JAK2, MPL, and CALR mutations is a rapid, simple, and sensitive technique in BCR-ABL1-negative MPNs with >10% mutant allele at the time of initial diagnosis. ..
  4. Han J, Lee I, Jang W, Shin S, Park J, Kim M. Identification of a novel de novo nonsense mutation of the NSD1 gene in monozygotic twins discordant for Sotos syndrome. Clin Chim Acta. 2017;470:31-35 pubmed publisher
  5. Lee J, Kim Y, Yi H, Diecke S, Kim J, Jung H, et al. Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis. Arthritis Res Ther. 2014;16:R41 pubmed publisher
    ..FLSs derived from RA and OA could be cell resources for iPSC reprogramming. Disease- and patient-specific iPSCs have the potential to be applied in clinical settings as source materials for molecular diagnosis and regenerative therapy. ..