Young Hyeh Ko

Summary

Affiliation: Sungkyunkwan University
Country: Korea

Publications

  1. pmc Primary central nervous system ALK positive anaplastic large cell lymphoma with predominantly leptomeningeal involvement in an adult
    Jae Sung Park
    Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Korea
    Yonsei Med J 54:791-6. 2013
  2. doi request reprint Enteropathy-associated T-cell lymphoma--a clinicopathologic and array comparative genomic hybridization study
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University, Kangnamgu, Seoul 135 710, Korea
    Hum Pathol 41:1231-7. 2010
  3. doi request reprint Aggressive natural killer cell leukemia: is Epstein-Barr virus negativity an indicator of a favorable prognosis?
    Young Hyeh Ko
    Department of Pathology, Division of Hematology and Oncology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea
    Acta Haematol 120:199-206. 2008
  4. pmc Systemic EBV+ T-cell lymphoma in elderly patients: comparison with children and young adult patients
    Sanghui Park
    Department of Pathology, Gil Medical Center, Gachon University of Medicine and Science, Namdonggu, Guwoldong, 1198, Incheon, South Korea
    Virchows Arch 453:155-63. 2008
  5. doi request reprint Metabolic tumor volumes by [18F]-fluorodeoxyglucose PET/CT correlate with occult metastasis in oral squamous cell carcinoma of the tongue
    Man Ki Chung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Ann Surg Oncol 16:3111-7. 2009
  6. doi request reprint Expression of mitotic checkpoint proteins BUB1B and MAD2L1 in salivary duct carcinomas
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Oral Pathol Med 39:349-55. 2010
  7. pmc The clinical usefulness of (18)F-FDG PET/CT for the evaluation of lymph node metastasis in periorbital malignancies
    Chung Hwan Baek
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 10:1-7. 2009
  8. doi request reprint 18F-FDG uptake and its clinical relevance in primary gastric lymphoma
    Jun Ho Yi
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkunkwan University School of Medicine, Seoul, Korea
    Hematol Oncol 28:57-61. 2010
  9. doi request reprint Treatment outcome of adult patients with Burkitt lymphoma: results using the LMB protocol in Korea
    Moon Ki Choi
    Division of Hematology Oncology, Department of Medicine Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, South Korea
    Ann Hematol 88:1099-106. 2009
  10. doi request reprint Clinical features and treatment outcomes of lymphoplasmacytic lymphoma: a single center experience in Korea
    Young Woong Won
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, South Korea
    Ann Hematol 89:1011-8. 2010

Collaborators

Detail Information

Publications87

  1. pmc Primary central nervous system ALK positive anaplastic large cell lymphoma with predominantly leptomeningeal involvement in an adult
    Jae Sung Park
    Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Korea
    Yonsei Med J 54:791-6. 2013
    ..We present the first case of primary leptomeningeal ALK-positive ALCL where the clinical course, pathologic characteristics and treatment modality are described as well as a review of literature...
  2. doi request reprint Enteropathy-associated T-cell lymphoma--a clinicopathologic and array comparative genomic hybridization study
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University, Kangnamgu, Seoul 135 710, Korea
    Hum Pathol 41:1231-7. 2010
    ..31 (2/5). These results suggest that the most prevalent type of enteropathy-associated T-cell lymphoma in this geographic region is type 2, and the genetic changes associated with it are similar to those in Western countries...
  3. doi request reprint Aggressive natural killer cell leukemia: is Epstein-Barr virus negativity an indicator of a favorable prognosis?
    Young Hyeh Ko
    Department of Pathology, Division of Hematology and Oncology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea
    Acta Haematol 120:199-206. 2008
    ..EBV-negative patients achieved complete remission, but tumors often relapsed after a short interval. In conclusion, EBV-negative ANKL is an uncommon malignancy that pursues a less aggressive clinical course than EBV-positive ANKL...
  4. pmc Systemic EBV+ T-cell lymphoma in elderly patients: comparison with children and young adult patients
    Sanghui Park
    Department of Pathology, Gil Medical Center, Gachon University of Medicine and Science, Namdonggu, Guwoldong, 1198, Incheon, South Korea
    Virchows Arch 453:155-63. 2008
    ..Additional factors related to senility may play a role in the disruption of homeostasis between the virus and the host's immune system...
  5. doi request reprint Metabolic tumor volumes by [18F]-fluorodeoxyglucose PET/CT correlate with occult metastasis in oral squamous cell carcinoma of the tongue
    Man Ki Chung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Ann Surg Oncol 16:3111-7. 2009
    ....
  6. doi request reprint Expression of mitotic checkpoint proteins BUB1B and MAD2L1 in salivary duct carcinomas
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Oral Pathol Med 39:349-55. 2010
    ..We aimed here to investigate the expression of mitotic checkpoint proteins benzimidazole 1 homolog beta (BUB1B) and mitosis arrest-deficient 2 like 1 (MAD2L1) in SDCs and to determine their possible role as surrogate prognostic markers...
  7. pmc The clinical usefulness of (18)F-FDG PET/CT for the evaluation of lymph node metastasis in periorbital malignancies
    Chung Hwan Baek
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 10:1-7. 2009
    ..The aim of this study was to assess the clinical role of (18)F-FDG PET/CT for the evaluation of lymph node metastasis in periorbital malignancies, compared with CT alone...
  8. doi request reprint 18F-FDG uptake and its clinical relevance in primary gastric lymphoma
    Jun Ho Yi
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkunkwan University School of Medicine, Seoul, Korea
    Hematol Oncol 28:57-61. 2010
    ....
  9. doi request reprint Treatment outcome of adult patients with Burkitt lymphoma: results using the LMB protocol in Korea
    Moon Ki Choi
    Division of Hematology Oncology, Department of Medicine Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, South Korea
    Ann Hematol 88:1099-106. 2009
    ..However, considering the high incidence of treatment-related deaths and the poor outcome of non-CR patients, risk-adapted modification of the induction phase is warranted...
  10. doi request reprint Clinical features and treatment outcomes of lymphoplasmacytic lymphoma: a single center experience in Korea
    Young Woong Won
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, South Korea
    Ann Hematol 89:1011-8. 2010
    ..The treatment approach was too heterogeneous to draw firm conclusions, however, and treatment recommendations in the future should utilize a uniform treatment strategy...
  11. doi request reprint Prognostic relevance of pretreatment quality of life in diffuse large B-cell lymphoma patients treated with rituximab-CHOP: Results from a prospective cohort study
    Hyun Ae Jung
    Department of Medicine, Division of Hematology Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, Korea
    Ann Hematol 91:1747-56. 2012
    ..This pretreatment QoL also independently predicted overall survival in the multivariate analysis. Thus, the pretreatment assessment of QoL may be a valid prognostic marker for DLBCL patients treated with R-CHOP...
  12. ncbi request reprint Can [18F]-fluorodeoxyglucose standardized uptake values of PET imaging predict pathologic extrathyroid invasion of thyroid papillary microcarcinomas?
    Han Sin Jeong
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Laryngoscope 116:2133-7. 2006
    ....
  13. doi request reprint Improved treatment outcome of primary mediastinal large B-cell lymphoma after introduction of rituximab in Korean patients
    Hee Kyung Ahn
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Korea
    Int J Hematol 91:456-63. 2010
    ..081). In conclusion, our comparison suggests that R-CHOP may increase response and reduce relapse resulting in prolongation of progression-free survival of patients with PMBCL...
  14. ncbi request reprint Effect of positive bone marrow EBV in situ hybridization in staging and survival of localized extranodal natural killer/T-cell lymphoma, nasal-type
    Jeeyun Lee
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Cancer Res 13:3250-4. 2007
    ..The aim of the study was to determine the effect of EBV-encoded RNA-1 in situ hybridization (EBER-1 ISH) in bone marrow specimens on survival outcome in patients with clinical stage I/II natural killer/T-cell lymphoma...
  15. doi request reprint Unusual presentation of Ewing sarcoma in the adrenal gland: a secondary malignancy from a survivor of Burkitt lymphoma
    Sung Hee Lim
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong Gangnam gu, Seoul 135 710, Korea
    Jpn J Clin Oncol 43:676-80. 2013
    ....
  16. doi request reprint Correlation between lymphatic vessel density and regional metastasis in squamous cell carcinoma of the tongue
    Man Ki Chung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Head Neck 32:445-51. 2010
    ..The aim of this study was to investigate the correlation between lymphatic vessel density in squamous cell carcinoma of the tongue and regional metastasis...
  17. doi request reprint Comparison of treatment strategies for patients with intestinal diffuse large B-cell lymphoma: surgical resection followed by chemotherapy versus chemotherapy alone
    Seok Jin Kim
    Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Blood 117:1958-65. 2011
    ..Surgical resection followed by chemotherapy might be an effective treatment strategy with acceptable QOL deterioration for localized intestinal DLBCL. This study was registered at www.clinicaltrials.gov as #NCT01043302...
  18. doi request reprint Bortezomib in combination with CHOP as first-line treatment for patients with stage III/IV peripheral T-cell lymphomas: a multicentre, single-arm, phase 2 trial
    Seok Jin Kim
    Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Eur J Cancer 48:3223-31. 2012
    ....
  19. doi request reprint Phase II trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed, stage IE to IIE, nasal, extranodal NK/T-Cell Lymphoma: Consortium for Improving Survival of Lymphoma study
    Seok Jin Kim
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Oncol 27:6027-32. 2009
    ....
  20. doi request reprint Tumor volume assessment by 18F-FDG PET/CT in patients with oral cavity cancer with dental artifacts on CT or MR images
    Chung Hwan Baek
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Nucl Med 49:1422-8. 2008
    ....
  21. doi request reprint Metabolic tumor volume of [18F]-fluorodeoxyglucose positron emission tomography/computed tomography predicts short-term outcome to radiotherapy with or without chemotherapy in pharyngeal cancer
    Man Ki Chung
    Departments of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Cancer Res 15:5861-8. 2009
    ....
  22. doi request reprint Intraoperative identification of suspicious palpable lymph nodes as an integral part of sentinel node biopsy in patients with breast cancer
    Young Jin Choi
    Department of Surgery, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Surg Today 38:390-4. 2008
    ..We studied the effectiveness of the biopsy of suspicious palpable lymph nodes (LNs) in reducing the number of FN results...
  23. doi request reprint Clinical features and treatment outcomes of non-Hodgkin's lymphomas involving rare extranodal sites: a single-center experience
    Jina Yun
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Haematol 123:48-54. 2010
    ..The involvement of certain organs such as the adrenal gland and ovaries is rare in non-Hodgkin's lymphoma (NHL). There are few studies comparing clinical features and prognosis based on the extranodal organ involved...
  24. ncbi request reprint Accuracy of MRI for estimating residual tumor size after neoadjuvant chemotherapy in locally advanced breast cancer: relation to response patterns on MRI
    Hyun Jung Kim
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Oncol 46:996-1003. 2007
    ....
  25. doi request reprint Reappraisal of KIT mutation in adenoid cystic carcinomas of the salivary gland
    Ji Youn Sung
    Department of Pathology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea
    J Oral Pathol Med 41:415-23. 2012
    ..While overexpression of KIT protein has been well documented in adenoid cystic carcinomas (ACCs), mutation of KIT gene has been a controversial issue. We wanted to evaluate clinical value of the KIT mutation and protein expression in ACC...
  26. doi request reprint Primary gastrointestinal follicular lymphoma: single-center 12-year experiences
    Youn Ju Na
    Samsung Medical Center, Seoul, Korea
    Hepatogastroenterology 59:751-3. 2012
    ..Primary gastrointestinal follicular lymphoma (GI-FL) is very rare and its natural course is barley known. This study aimed to evaluate the clinical characteristics of primary gastrointestinal follicular lymphoma (GI-FL)...
  27. ncbi request reprint The impact of Epstein-Barr virus status on clinical outcome in diffuse large B-cell lymphoma
    Sarah Park
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong Kangnam Ku, Seoul 135 710, Korea
    Blood 110:972-8. 2007
    ..9-fold (95% CI, 1.1-8.1) risk for death. Taken together, DLBCL patients with EBER in situ hybridization+ pursued more rapidly deteriorating clinical course with poorer treatment response, survival, and progression-free survival...
  28. doi request reprint Hypoxia-associated protein expression in primary central nervous system diffuse large B-cell lymphoma: does it predict prognosis?
    Jung A Kim
    Division of Hematology Oncology, Department of Medicine, Seoul Paik Hospital, Inje University School of Medicine, Seoul, Korea
    Leuk Lymphoma 52:205-13. 2011
    ..In conclusion, hypoxia-associated proteins were expressed in PCNSL, suggesting a hypoxic microenvironment. However, the prognostic relevance of these proteins for PCNSL was not demonstrated in this study...
  29. doi request reprint Incidence, risk factors and clinical features of venous thromboembolism in newly diagnosed lymphoma patients: results from a prospective cohort study with Asian population
    Lee Chun Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Thromb Res 130:e6-12. 2012
    ..Venous thromboembolism (VTE) may be associated with treatment failure rate and quality of life deterioration in lymphoma patients. However, the majority of data regarding VTE has come from retrospective studies done in Western countries...
  30. doi request reprint Twist1 is an independent prognostic factor of esophageal squamous cell carcinoma and associated with its epithelial-mesenchymal transition
    Keun Woo Lee
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Gangnam Gu, Seoul, Korea
    Ann Surg Oncol 19:326-35. 2012
    ..However, its specific role is different depending on the type of cancer. The functional role and clinical significance of Twist1 in esophageal squamous cell carcinoma (ESCC) have been rarely studied...
  31. ncbi request reprint [Microsatellite instability in gastric B-cell lymphoma]
    Hyuk Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Gastroenterol 47:205-12. 2006
    ..However, the role of MSI in the development of gastric B-cell lymphomas remains unsettled. We aimed to investigate the clinical significance of MSI in patients with gastric B-cell lymphoma...
  32. ncbi request reprint Marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue: imaging findings in 21 patients
    Young A Bae
    Department of Radiology, Samsung Medical Center, 50, IlWon Dong, Kangnam Ku, Seoul 135 710, Korea
    Chest 133:433-40. 2008
    ..Few articles have been published on imaging findings of marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue (BALT) of the lung. We present CT scan and 18F-fluorodeoxyglucose (FDG) PET scan findings of the disease...
  33. ncbi request reprint Primary pulmonary non-Hodgkin's lymphoma
    Jung Han Kim
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 135 710 Seoul, Korea
    Jpn J Clin Oncol 34:510-4. 2004
    ..Although there have been a few reviews of this lymphoma, clinical features, diagnostic procedure, optimal management and prognostic factors have not been well defined...
  34. doi request reprint Clinical features and treatment outcomes of adult B- and T-lymphoblastic lymphoma: results of multicentre analysis in Korea
    Myung Hee Chang
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Leuk Lymphoma 50:1119-25. 2009
    ..05). In conclusion, clinical features and treatment outcome of Asian adult LBL were comparable to previous results, and the prognosis is still poor despite intensive chemotherapy...
  35. doi request reprint Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ
    Kyeung Min Joo
    Department of Anatomy and Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135 710, Korea
    Cell Rep 3:260-73. 2013
    ..Together, the patient-specific orthotopic GBM xenograft library represent the preclinically and clinically valuable "patient tumor's phenocopy" that represents molecular and functional heterogeneity of GBMs...
  36. pmc The spectrum of Epstein-Barr virus-associated lymphoproliferative disease in Korea: incidence of disease entities by age groups
    Eun Yoon Cho
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 23:185-92. 2008
    ..In old patients, decreased immunity associated with old age and environmental cofactors may provoke the development of peripheral T cell lymphoma, unspecified, and diffuse large B cell lymphoma...
  37. doi request reprint Insulin-like growth factor binding protein-3, in association with IGF-1 receptor, can predict prognosis in squamous cell carcinoma of the head and neck
    Jong Mu Sun
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Oral Oncol 47:714-9. 2011
    ..017). In conclusion, it is suggested that IGFBP-3 expression, in a state of co-expression with IGF-1R, can predict poor prognosis in SCCHN patients...
  38. doi request reprint Primary cutaneous Epstein-Barr virus-associated T-cell lymphoproliferative disorder-2 cases with unusual, prolonged clinical course
    Sanghui Park
    Department of Pathology, Gil Medical Center, Gachon University, Incheon, Korea
    Am J Dermatopathol 32:832-6. 2010
    ..We suggest that these cases represent a peculiar subtype of EBV+ cutaneous T-cell lymphoma, with a tendency to localize in the skin of the extremities and has an indolent clinical course...
  39. doi request reprint Clinical features and prognostic factors of patients with "peripheral T cell lymphoma, unspecified"
    Yuna Lee
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Ann Hematol 88:111-9. 2009
    ..1 months (95% CI, 0.0-40.5) and 35.5 months (95% CI, 1.2-69.8), respectively. Poor performance status, the presence of B symptoms, IPI scores >or=3 and PIT class >or=2 were predictive prognostic factors for survival...
  40. doi request reprint Extent of local invasion and safe resection in cT1-2 tonsil cancer
    JungBok Lee
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Surg Oncol 107:469-73. 2013
    ..Thus, we aim to determine the extent of local invasion in terms of mucosal spread and deep infiltration in stage T1-2 tonsil cancer...
  41. doi request reprint Genomic copy number alterations associated with the early brain metastasis of non-small cell lung cancer
    Hye Won Lee
    Cancer Stem Cell Research Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Republic of Korea
    Int J Oncol 41:2013-20. 2012
    ..Although more validation is needed, the genetic signatures elucidated in this study help to identify useful molecular markers deļ¬ning an NSCLC patient subgroup at risk of early BM, guiding therapeutic decisions...
  42. pmc Stereotactic core-needle biopsy of non-mass calcifications: outcome and accuracy at long-term follow-up
    Boo Kyung Han
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 4:217-23. 2003
    ....
  43. doi request reprint Correlation of lymphatic vessel density and vascular endothelial growth factor with nodal metastasis in papillary thyroid microcarcinoma
    Man Ki Chung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Head Neck 34:846-51. 2012
    ....
  44. doi request reprint Intraoral sonography-assisted resection of T1-2 tongue cancer for adequate deep resection
    Chung Hwan Baek
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Otolaryngol Head Neck Surg 139:805-10. 2008
    ..To investigate the clinical usefulness of intraoral sonography-assisted resection for securing adequate deep resection margins in T1-2 tongue cancers...
  45. doi request reprint Expression of JL1 in Burkitt lymphoma is associated with improved overall survival
    Ilseon Hwang
    Department of Pathology, Keimyung University School of Medicine, 194 Dongsan dong, Choong Ku, Daegu, South Korea
    Virchows Arch 459:353-9. 2011
    ..043) analysis. JL1 expression in Burkitt lymphoma was positively correlated with overall survival and better response to chemotherapy, suggesting that JL1 may be a prognostic marker for risk stratification in these patients...
  46. ncbi request reprint Granzyme B leakage-induced apoptosis is a crucial mechanism of cell death in nasal-type NK/T-cell lymphoma
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Lab Invest 87:241-50. 2007
    ..These results suggested that granzyme B leakage induces cell death in NK/T-cell lymphomas via both caspase-dependent and -independent mechanisms, and this leads to the extensive necrosis that is commonly seen in NK/T-cell lymphoma...
  47. doi request reprint Genomic profiling combined with gene expression profiling in primary central nervous system lymphoma
    Chang Ohk Sung
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Seoul, South Korea
    Blood 117:1291-300. 2011
    ..In conclusion, this study identified novel tumor suppressor genes that may serve as therapeutic targets of PCNSL...
  48. doi request reprint Methylation of p16INK4A and mitotic arrest defective protein 2 (MAD2) genes in gastric marginal-zone B-cell lymphomas
    Sanghui Park
    Department of Pathology, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Republic of Korea
    Acta Haematol 120:217-24. 2008
    ..The objective of this study was to investigate the role of promoter methylation of p16(INK4A) and MAD2 genes in gastric marginal-zone B-cell lymphoma (MZBCL)...
  49. pmc Primary CNS lymphoma other than DLBCL: a descriptive analysis of clinical features and treatment outcomes
    Taekyu Lim
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, South Korea
    Ann Hematol 90:1391-8. 2011
    ..In conclusion, primary CNS lymphoma other than DLBCL occurred more in younger patients and showed a generally good prognosis, except for Burkitt's lymphoma. Further research on treatment strategies for Burkitt's lymphoma is needed...
  50. pmc EBV-Positive T/NK-Cell Lymphoproliferative Disease of Childhood
    Mineui Hong
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Pathol 47:137-47. 2013
    ..This study reviewed the clinicopathological spectrum of EBV-associated T- and natural killer (NK)-cell LPD, including STLPD and CAEBV infection, with an analysis of T-cell clonality...
  51. doi request reprint Isolation of side population cells in B-cell non-Hodgkin's lymphomas
    Mi Ran Lee
    Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Haematol 129:10-7. 2013
    ..Side population (SP) cells are characterized by the ability to exclude Hoechst 33342 dye due to high expression of the ATP-binding cassette transporter. This ability is associated with drug-resistant characteristics of cancer stem cells...
  52. ncbi request reprint Clinicopathologic features and treatment outcomes in malignant lymphoma of pediatric and young adult patients in Korea: comparison of korean all-ages group and Western younger age group
    In Gyu Hwang
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Lymphoma Myeloma 7:580-6. 2007
    ..The aim of this study is to define distinctive clinicopathologic features of malignant lymphoma in pediatric and young adult patients, particularly in Korea...
  53. ncbi request reprint Genome-wide array-based comparative genomic hybridization of ocular marginal zone B cell lymphoma: comparison with pulmonary and nodal marginal zone B cell lymphoma
    Won Seog Kim
    Division of Hemato Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Genes Chromosomes Cancer 46:776-83. 2007
    ..Deletion of chromosome band 6q23.3 in ocular MZBCL is a novel finding and may constitute a crucial genetic alteration in the pathogenesis of ocular MZBCL...
  54. pmc A case of coexistent angiosarcoma and follicular carcinoma of the thyroid
    Na Rae Kim
    Department of Pathology, Gachon Medical School, Gil Medical Center, Incheon, Korea
    J Korean Med Sci 18:908-13. 2003
    ..This combination has never been described in the literature. Although restricted to a single case, the present case further supports that angiosarcoma is a true existent entity rather than a variant of anaplastic carcinoma...
  55. doi request reprint Discrepant immunophenotypic characteristics between the lymph node and bone marrow in two mixed-phenotype acute leukemia patients
    Min Jung Song
    Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Lab Med 29:396-401. 2009
    ..Therefore, integration of all the relevant results, including those of the bone marrow studies, may be helpful for accurate diagnosis and selecting appropriate treatment modalities...
  56. doi request reprint Methylation and API2/MALT1 fusion in colorectal extranodal marginal zone lymphoma
    Dong H Sinn
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Mod Pathol 22:314-20. 2009
    ..Our results suggest that methylation profiles define a clinically more aggressive subgroup and multiclonal origin for marginal zone B-cell lymphoma of MALT with multiorgan involvement...
  57. ncbi request reprint Intestinal lymphoma: exploration of the prognostic factors and the optimal treatment
    Jeeyun Lee
    Division of Hematology Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Leuk Lymphoma 45:339-44. 2004
    ..In localized diseases (stage 1 and 2), the primary surgical treatment had the most favorable influence on failure-free survival (P < 0.05). The resection of localized intestinal lymphoma may be appropriate as the primary treatment...
  58. doi request reprint Measurement of tyrosine hydroxylase transcripts in bone marrow using biopsied tissue instead of aspirates for neuroblastoma
    Seung Tae Lee
    Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Pediatr Blood Cancer 55:273-8. 2010
    ..However, its clinical utility following chemotherapy has not been thoroughly investigated...
  59. doi request reprint Should children with non-Hodgkin lymphoma be treated with different protocols according to histopathologic subtype?
    Soo Hyun Lee
    Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Pediatr Blood Cancer 60:1842-7. 2013
    ..This study was performed to evaluate the efficacy of this protocol in children with non-Hodgkin lymphoma (NHL), irrespective of histopathologic subtype...
  60. doi request reprint World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphoma in Korea: a retrospective study at a single tertiary institution
    Ji Hye Park
    Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Am Acad Dermatol 67:1200-9. 2012
    ..Data are limited regarding the features of cutaneous lymphoma (CL) presented according to the World Health Organization (WHO) and the European Organization for Research and Treatment of Cancer (EORTC) classification (2005) in Korea...
  61. doi request reprint Efficacy of continuous venovenous hemofiltration with chemotherapy in patients with Burkitt lymphoma and leukemia at high risk of tumor lysis syndrome
    Kyung A Choi
    Division of Nephrology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, South Korea
    Ann Hematol 88:639-45. 2009
    ..The 1-year event-free survival and overall survival rates were both 82%. In conclusion, chemotherapy combined with CVVH might be effective and safe in patients with advanced Burkitt lymphoma and leukemia at a high risk of developing TLS...
  62. doi request reprint Expression of JL1 is an effective adjunctive marker of leukemia cutis
    Young Soo Park
    Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Arch Pathol Lab Med 134:95-102. 2010
    ..Here, we introduce JL1, a novel leukemia-associated surface antigen, which is not expressed in mature human tissue but in cortical thymocytes and small subpopulations of bone marrow hematopoietic precursors...
  63. doi request reprint Composite marginal zone B cell lymphoma and enteropathy-type T cell lymphoma of the stomach: a case report
    Won Kyoung Yun
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, Republic of Korea
    Eur J Gastroenterol Hepatol 20:791-5. 2008
    ..The simultaneous occurrence of mucosa-associated lymphoid tissue lymphoma and enteropathy-type T cell lymphoma is exceptional and has never been reported. We discuss the possible pathogenetic relationship between the two neoplasms...
  64. pmc Gastric syphilis mimicking adenocarcinoma: a case report
    Yoon La Choi
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 21:559-62. 2006
    ....
  65. doi request reprint Aggressive B cell lymphomas of the gastrointestinal tract: clinicopathologic and genetic analysis
    Song Yi Choi
    Department of Pathology, Chungbuk National University Hospital, Cheongju, South Korea
    Virchows Arch 459:495-502. 2011
    ..The overall prognosis of patients with DLBCL/BL was the worst among aggressive B cell lymphomas. DLBCL/BL is uncommon category of B cell lymphoma in the GI tract with aggressive clinical course despite of intensive chemotherapy...
  66. ncbi request reprint Egr-1, a new downstream molecule of Epstein-Barr virus latent membrane protein 1
    Joo Hyun Kim
    Biomedical Research Institute, Samsung Medical Center, 50 Irwon dong, Kangnam Gu, Seoul 135 710, Republic of Korea
    FEBS Lett 581:623-8. 2007
    ..Third, Egr-1 knockdown decreased LMP1-induced expression of Bfl-1. Similar relationships among EBV infection, Egr-1 and drug resistance were also observed in tissues of peripheral T-cell lymphoma-unspecified (PTCL-u) patients...
  67. ncbi request reprint Expression of CD56 antigen in Langerhans cell histiocytosis associated with T-lymphoblastic lymphoma in a same lymph node
    Young Hyeh Ko
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam Gu, Ilwon dong 50, 135 710 Seoul, South
    Virchows Arch 448:90-4. 2006
    ..Neither admixed eosinophils nor multinucleated giant cells were observed. The pathogenetic mechanism of CD56 expression in LCH associated with LBL is discussed...
  68. doi request reprint ALK-positive diffuse large B-cell lymphoma: report of three cases
    Hyoun Wook Lee
    Department of Pathology, Dong A University, Pusan, Korea
    Hematol Oncol 26:108-13. 2008
    ..These three cases suggest that different types of cytogenetic aberrations may involve the ALK gene in ALK-positive diffuse large B-cell lymphoma leading to peculiar immunohistochemical staining patterns...
  69. doi request reprint A unique case of blastoid variant of mantle cell lymphoma with an aberrant CD5-/CD10+/Bcl-6+/CD56+ immunophenotype: a case report
    Sanghui Park
    Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea
    Tumori 98:e111-4. 2012
    ..Cases of CD56-positive mantle cell lymphoma (MCL) have not previously been described in the literature. We present a case of CD56-positive MCL. To the best of our knowledge, this is the first case report of MCL expressing CD56...
  70. doi request reprint Endoscopic findings in mantle cell lymphoma with gastrointestinal tract involvement
    Jung Ha Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Haematol 127:129-34. 2012
    ..Mantle cell lymphoma (MCL) of the gastrointestinal (GI) tract is a rare disease with a poor prognosis. The aim of this study was to determine clinical and endoscopic characteristics of patients with GI MCL...
  71. pmc Bone marrow is involved in less than 10% of patients with nasal-type NK/T cell lymphoma at initial diagnosis
    Chang Okh Sung
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea
    J Korean Med Sci 19:229-33. 2004
    ..In conclusion, marrow involvement in nasal NK/T cell lymphoma is infrequent at initial diagnosis, and EBV ISH is a useful technique for identifying the minor subgroup of patients which have easily overlooked neoplastic involvement...
  72. doi request reprint Autologous hematopoietic stem cell transplantation in extranodal natural killer/T cell lymphoma: a multinational, multicenter, matched controlled study
    Jeeyun Lee
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Biol Blood Marrow Transplant 14:1356-64. 2008
    ..These findings suggest that, in particular, patients in CR with high NKIPI risk scores at diagnosis should receive full consideration for HSCT...
  73. pmc Multidetector CT and MR imaging of cardiac tumors
    Eun Young Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    Korean J Radiol 10:164-75. 2009
    ..Presurgical assessment of malignant cardiac tumors with the use of MDCT and MRI may allow determination of the resectability of tumors and planning for the reconstruction of cardiac chambers...
  74. pmc Nasal chondromesenchymal hamartoma: CT and MR imaging findings
    Ji Eun Kim
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 10:416-9. 2009
    ..A nasal chondromesenchymal hamartoma is a rare benign pediatric hamartoma that can simulate malignancy. Although rare, knowledge of this entity is essential to avoid potentially harmful therapies...
  75. pmc De novo CD5 positive diffuse large B-cell lymphomas with bone marrow involvement in Korean
    Sun Young Kong
    Departments of Laboratory Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 19:815-9. 2004
    ..To the best of our knowledge, this is the first report on de novo CD5+ DLBCL in Koreans...
  76. ncbi request reprint Epstein-Barr virus infected natural killer cell lymphoma in a patient with hypersensitivity to mosquito bite
    Jae Hoon Cho
    Department of Otolaryngology, Head and Neck Surgery, Kounkuk University Medical School, Seoul, South Korea
    J Infect 52:e173-6. 2006
    ..He was diagnosed as having Tokura-Ishihara disease and receives chemotherapy now. Here, we report a case of this disease with a precise pathological description on the lymph node biopsy...
  77. doi request reprint Prognostic significance of O6-methylguanine DNA methyltransferase and p57 methylation in patients with diffuse large B-cell lymphomas
    Sun Mi Lee
    Department of Pathology, The Catholic University of Korea, Seoul, Korea
    APMIS 117:87-94. 2009
    ..Our results demonstrate that aberrant promoter methylation of MGMT and p57 is an additional biological marker for predicting increased overall survival in patients with DLBCL...
  78. doi request reprint Nasal polyps with metaplastic ossification: CT and MR imaging findings
    Yi Kyung Kim
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Kangnam Ku, Seoul, 135 710, South Korea
    Neuroradiology 52:1179-84. 2010
    ..Metaplastic ossification is a rare event in nasal polyps. The purpose of this study was to review the computed tomography (CT) and magnetic resonance (MR) imaging findings of nasal polyps with metaplastic ossification...
  79. doi request reprint Canaliculocele presenting as a medial canthal mass
    Jin Chul Kim
    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Ophthal Plast Reconstr Surg 25:236-8. 2009
    ..Canaliculocele should be considered in the differential diagnoses of a medial canthal mass...
  80. pmc Primary T-cell lymphoma of the thyroid associated with Hashimoto's thyroiditis, histologically mimicking MALT-lymphoma
    Na Rae Kim
    Department of Pathology, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea
    J Korean Med Sci 25:481-4. 2010
    ..This is the second case of cytotoxic T-cell lymphoma reported in the thyroid gland so far. Unique association between thyroid follicles and neoplastic lymphocytes may be characteristic feature of this type of T-cell lymphoma...
  81. pmc MET expression in sporadic renal cell carcinomas
    Jong Sun Choi
    Department of Pathology, Cheil General Hospital, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, Korea
    J Korean Med Sci 21:672-7. 2006
    ..In case of MET expression observed in clear cell RCC, it might correlate with those clinicopathological parameters implying aggressive behavior...
  82. ncbi request reprint Intraoperative examination of sentinel lymph nodes by ultrarapid immunohistochemistry in breast cancer
    Young Jin Choi
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul 135 710, Korea
    Jpn J Clin Oncol 36:489-93. 2006
    ..The present study was undertaken to develop a reliable protocol for the ultrarapid IHC of SLNs...
  83. doi request reprint Clinicopathologic characteristics of CD99-positive diffuse large B-cell lymphoma
    Sang Pyo Lee
    Department of Medicine, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea
    Acta Haematol 125:167-74. 2011
    ..However, few studies have investigated the prognostic impact of CD99 in diffuse large B-cell lymphoma (DLBCL)...
  84. pmc Isolated biliary granulocytic sarcoma followed by acute myelogeneous leukemia with multilineage dysplasia: a case report and literature review
    Chang Ohk Sung
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 21:550-4. 2006
    ..A histologic evaluation by aggressive diagnostic intervention is important and may improve prognosis...
  85. doi request reprint A retrospective study to compare two methotrexate-based regimens for primary central nervous system lymphoma
    Ji Eun Uhm
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Leuk Lymphoma 50:1110-8. 2009
    ....
  86. ncbi request reprint Synchronous adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma in a single stomach
    Sun Young Lee
    Department of Medicine, Konkuk University College of Medicine, Seoul, Korea
    Jpn J Clin Oncol 35:591-4. 2005
    ..Synchronous gastric adenocarcinoma and primary gastric mucosa-associated lymphoid tissue (MALT) lymphoma are rare, and the characteristics of these tumors are still unclear...
  87. ncbi request reprint A novel complex t(2;5;13)(p23;q35;q14) in small cell variant type anaplastic large cell lymphoma with peripheral involvement
    Sun Young Kong
    Department of Laboratory Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, 50 Ilwon Dong, Gangnam Gu, Seoul, Republic of Korea
    Cancer Genet Cytogenet 154:183-5. 2004
    ..A cytogenetic study showed a complex translocation, t(2;5;13)(p23;q35;q14). Fluorescence in situ hybridization with ALK break-apart probes confirmed that the three-break rearrangement involves the ALK gene...