Chang Young Jang

Summary

Affiliation: Sookmyung Women's University
Country: Korea

Publications

  1. doi request reprint Mitotic kinases regulate MT-polymerizing/MT-bundling activity of DDA3
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Biochem Biophys Res Commun 408:174-9. 2011
  2. doi request reprint DDA3 associates with MCAK and controls chromosome congression
    Chang Young Jang
    School of Pharmacy, Sookmyung Women s University, Seoul 140 742, Republic of Korea
    Biochem Biophys Res Commun 407:610-4. 2011
  3. pmc Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
    Akiko Seki
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Science 320:1655-8. 2008
  4. pmc DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 181:255-67. 2008
  5. pmc Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain
    Jim Wong
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mol Biol Cell 19:2083-91. 2008
  6. pmc Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
    Akiko Seki
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 181:65-78. 2008
  7. ncbi request reprint The N-terminal domain of DDA3 regulates the spindle-association of the microtubule depolymerase Kif2a and controls the mitotic function of DDA3
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA, USA
    Cell Cycle 8:3165-71. 2009
  8. pmc Phospho-regulation of DDA3 function in mitosis
    Chang Young Jang
    Department of Biological Sciences, Stanford University, CA 94305 5020, USA
    Biochem Biophys Res Commun 393:259-63. 2010
  9. pmc FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle
    Hui Zhu
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 183:835-48. 2008
  10. pmc Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Sci 122:1334-41. 2009

Collaborators

  • Guowei Fang
  • Hyunil Ha
  • Chan Soo Shin
  • Ling Chen
  • Hui Zhu
  • Akiko Seki
  • Byung Soo Choi
  • Jung Min Lee
  • John R Yates
  • Jim Wong
  • Judith A Coppinger
  • Ji Eun Park
  • Juhyun Lee
  • Sun Young Ji
  • Hyojung Park
  • Hea Young Park
  • Dong Seok Lee
  • Zang Hee Lee
  • A Long Sae Mi Noh
  • Mijung Yim
  • Ju Hee Kang
  • Ting Zheng
  • Haining Du
  • Robert Lerrigo

Detail Information

Publications12

  1. doi request reprint Mitotic kinases regulate MT-polymerizing/MT-bundling activity of DDA3
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Biochem Biophys Res Commun 408:174-9. 2011
    ..We conclude that kinases control the function of DDA3 in the cell cycle by regulating its MT-polymerizing/bundling activities through sequential phosphorylation...
  2. doi request reprint DDA3 associates with MCAK and controls chromosome congression
    Chang Young Jang
    School of Pharmacy, Sookmyung Women s University, Seoul 140 742, Republic of Korea
    Biochem Biophys Res Commun 407:610-4. 2011
    ..On the other hand, the localization of chromosomal passenger complex (CPC) and the kinase activity of Aurora B are normal in DDA3-depleted cells. We conclude that MCAK and CENP-E are involved in DDA3-mediated chromosome congression...
  3. pmc Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry
    Akiko Seki
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Science 320:1655-8. 2008
    ..Thus, Bora and Aur-A control mitotic entry, which provides a mechanism for one of the most important yet ill-defined events in the cell cycle...
  4. pmc DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 181:255-67. 2008
    ..Thus, DDA3 represents a new class of MT-destabilizing protein that controls spindle dynamics and mitotic progression by regulating MT depolymerases...
  5. pmc Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain
    Jim Wong
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mol Biol Cell 19:2083-91. 2008
    ..We concluded that phosphorylation of HURP by Aurora A provides a regulatory mechanism for the control of spindle assembly and function...
  6. pmc Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
    Akiko Seki
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 181:65-78. 2008
    ..We conclude that tight regulation of the Bora protein by its synthesis and degradation is critical for cell cycle progression...
  7. ncbi request reprint The N-terminal domain of DDA3 regulates the spindle-association of the microtubule depolymerase Kif2a and controls the mitotic function of DDA3
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA, USA
    Cell Cycle 8:3165-71. 2009
    ..The C-terminal domain confers its ability to associate with the mitotic spindle, while the regulatory N-terminal domain controls the microtubule-binding by the C-terminal domain and determines the cellular activity of the DDA3 protein...
  8. pmc Phospho-regulation of DDA3 function in mitosis
    Chang Young Jang
    Department of Biological Sciences, Stanford University, CA 94305 5020, USA
    Biochem Biophys Res Commun 393:259-63. 2010
    ..We conclude that the mitotic function of DDA3 is regulated by phosphorylation on the Ser225 residue...
  9. pmc FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle
    Hui Zhu
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Biol 183:835-48. 2008
    ..Our study provides a biochemical mechanism for MT-dependent MT amplification and for the maturation of kinetochore fibers in mammalian cells...
  10. pmc Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a
    Chang Young Jang
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    J Cell Sci 122:1334-41. 2009
    ....
  11. doi request reprint Sirt3 controls chromosome alignment by regulating spindle dynamics during mitosis
    Byung Soo Choi
    Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women s University, Seoul 140 742, Republic of Korea
    Biochem Biophys Res Commun 444:662-9. 2014
    ..The findings collectively suggest that Sirt3 is not a tubulin deacetylase but regulates the attachment of spindle MTs to the kinetochore and the subsequent chromosome alignment by increasing spindle dynamics. ..
  12. doi request reprint 5-Lipoxygenase mediates RANKL-induced osteoclast formation via the cysteinyl leukotriene receptor 1
    Jung Min Lee
    College of Pharmacy, Sookmyung Women s University, Seoul 140 742, Republic of Korea
    J Immunol 189:5284-92. 2012
    ..Taken together, the results of this study demonstrate that 5-LO is a key mediator of RANKL-induced osteoclast formation and possibly a novel therapeutic target for bone-resorption diseases...