Jaeyoung Ko


Affiliation: Skin Research Institute
Country: Korea


  1. Le T, Lee E, Lee J, Hong A, Yim C, Yang I, et al. Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium Saccharomonospora sp. Mar Drugs. 2019;17: pubmed publisher
    ..Saccharoquinoline (1) was found to have cytotoxicity against the HCT-116 cancer cell line by inducing G1 arrest, which leads to cell growth inhibition. ..
  2. Yang I, Lee J, Lee J, Hahn D, Chin J, Won D, et al. Scalalactams A⁻D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge. Molecules. 2018;23: pubmed publisher
    ..Scalalactams A⁻D (14) did not show FXR antagonistic activity nor cytotoxicity up to 100 μM. ..
  3. Jeong H, Lee C, Choi J, Hong Y, Shin S, Park J, et al. Flavokawains B and C, melanogenesis inhibitors, isolated from the root of Piper methysticum and synthesis of analogs. Bioorg Med Chem Lett. 2015;25:799-802 pubmed publisher
    ..Compound 1b was the most potent of these with an IC50 value of 2.3μM in melanogenesis inhibition assays using MSH-activated B16 melanoma cells. ..
  4. Kim D, Lee E, Lee J, Leutou A, Shin Y, Choi B, et al. Antartin, a Cytotoxic Zizaane-Type Sesquiterpenoid from a Streptomyces sp. Isolated from an Antarctic Marine Sediment. Mar Drugs. 2018;16: pubmed publisher
    ..Antartin (1) showed cytotoxicity against A549, H1299, and U87 cancer cell lines by causing cell cycle arrest at the G1 phase. ..
  5. Wang L, Oh J, Kim H, Lee W, Cui Y, Lee H, et al. Protective effect of polysaccharides from Celluclast-assisted extract of Hizikia fusiforme against hydrogen peroxide-induced oxidative stress in vitro in Vero cells and in vivo in zebrafish. Int J Biol Macromol. 2018;112:483-489 pubmed publisher
    ..These results suggest that HFPS may be useful as an antioxidant in medical and cosmetic industries. ..
  6. Jeong K, Yang M, Jin Y, Kim E, Ko J, Lee J. Identification of Major Flavone C-Glycosides and Their Optimized Extraction from Cymbidium kanran Using Deep Eutectic Solvents. Molecules. 2017;22: pubmed publisher
    ..441 mg g-1 flavone C-glycosides including 1.933 mg g-1 vicenin-2 was obtained. This total yield was 196%, 131%, and 71% more than those obtained using 100% methanol, water, and 70% methanol, respectively. ..