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In Sup Kil
Affiliation: Skin Research Institute
Ji Y, Chae S, Lee H, Park I, Kim C, Ismail T, et al. Peroxiredoxin5 controls vertebrate ciliogenesis by modulating mitochondrial ROS. Antioxid Redox Signal. 2018;: pubmed publisher
..The loss of Prdx5 is associated with excessive production of ROS resulting in mitochondrial dysfunction and aberrant ciliogenesis. ..
Kim J, Lee S, Bae I, Shin D, Min D, Ham M, et al. Pyruvate Protects against Cellular Senescence through the Control of Mitochondrial and Lysosomal Function in Dermal Fibroblasts. J Invest Dermatol. 2018;138:2522-2530 pubmed publisher
..These results suggest that the pyruvate deprivation-induced senescence model can be used to study the connection between metabolism and senescence under normal conditions. ..