Yeong Wook Song


Affiliation: Seoul National University
Country: Korea


  1. Song Y, Lee E, Koh E, Cha H, Yoo B, Lee C, et al. Assessment of comparative pain relief and tolerability of SKI306X compared with celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clinical trial. Clin Ther. 2007;29:862-873 pubmed publisher
    ..Those studies found that SKI306X was associated with an anti-inflammatory and analgesic effect, and that it can delay the destruction of cartilage in rheumatoid arthritis (RA)...
  2. Kang E, Go D, Mimori T, Lee S, Kwon H, Park J, et al. Novel susceptibility alleles in HLA region for myositis and myositis specific autoantibodies in Korean patients. Semin Arthritis Rheum. 2019;: pubmed publisher
    ..Novel myositis susceptibility alleles, HLA-DRB1*12:02 and HLA-DRB1*14:03, were identified, together with MSA-associated HLA alleles unique to Korean patients with myositis. ..
  3. Lee J, Lee E, Ha Y, Kang E, Lee Y, Song Y. Serum KL-6 levels reflect the severity of interstitial lung disease associated with connective tissue disease. Arthritis Res Ther. 2019;21:58 pubmed publisher
    ..Serum KL-6 levels were increased in CTD-ILD patients and had a positive correlation with CT grade and a negative correlation with FVC and DLCO. Serum KL-6 levels may reflect CTD-ILD severity. ..
  4. Park E, Lee E, Lee Y, Ha Y, Yoo W, Choi B, et al. Infliximab biosimilar CT-P13 therapy in patients with Takayasu arteritis with low dose of glucocorticoids: a prospective single-arm study. Rheumatol Int. 2018;38:2233-2242 pubmed publisher
    ..There were no serious adverse events. Treatment with CT-P13 may lead to improvement in clinical, radiographic, and serological activities with lower glucocorticoid requirement in TAK.Trial registration number NCT02457585. ..
  5. Kim J, Lee S, Bae I, Shin D, Min D, Ham M, et al. Pyruvate Protects against Cellular Senescence through the Control of Mitochondrial and Lysosomal Function in Dermal Fibroblasts. J Invest Dermatol. 2018;138:2522-2530 pubmed publisher
    ..These results suggest that the pyruvate deprivation-induced senescence model can be used to study the connection between metabolism and senescence under normal conditions. ..
  6. Choi I, Baek H, Cho C, Lee Y, Chung W, Park Y, et al. Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial. BMC Musculoskelet Disord. 2014;15:375 pubmed publisher
    ..However, more patients in the pelubiprofen group experienced ADR and the frequency of gastrointestinal ADRs was higher in the pelubiprofen group. identifier: NCT01781702. ..
  7. request reprint
    Choi B, Oh H, Lee Y, Song Y. Prevalence and clinical impact of fibromyalgia in patients with primary Sjögren's syndrome. Clin Exp Rheumatol. 2016;34:S9-13 pubmed
    ..0072) decreased compared to those without FM. Our study showed that FM was prevalent in pSS. FM was associated with higher ESSPRI and more severe depression. ..
  8. Choi B, Yoon M, Shin K, Lee Y, Song Y. Characteristics of pleural effusions in systemic lupus erythematosus: differential diagnosis of lupus pleuritis. Lupus. 2015;24:321-6 pubmed publisher
    ..30 (0.30-5.66) versus 0.7 (0.12-1.47) mg/dl, p = 0.0062). In conclusion, pleural fluid ANA titer and serum CRP levels are significantly increased in lupus pleuritis. ..
  9. Lee J, Choi I, Kim J, Kim K, Lee E, Lee E, et al. Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA. BMC Musculoskelet Disord. 2015;16:190 pubmed publisher
    ..001, respectively). Anti-P. gingivalis and anti-ENO1 antibody titers were correlated with the severity of PD in RA. Anti-ENO1 antibody titers, but not anti-P. gingivalis antibody titers, were further associated with RA disease activity. ..

More Information


  1. Chung S, Ha Y, Kang E, Lee Y, Song Y. The psychosocial status of the family members of rheumatoid arthritis patients in Korea. Rheumatol Int. 2016;36:719-24 pubmed publisher
    ..Our data show that the family members of RA patients have an increased prevalence of stress and depression. Physicians who treat RA patients should also consider the needs and the burden of family members. ..
  2. Shin K, Park S, Park W, Baek H, Lee Y, Kang S, et al. Monthly Oral Ibandronate Reduces Bone Loss in Korean Women With Rheumatoid Arthritis and Osteopenia Receiving Long-term Glucocorticoids: A 48-week Double-blinded Randomized Placebo-controlled Investigator-initiated Trial. Clin Ther. 2017;39:268-278.e2 pubmed publisher
    ..Longer follow-up studies are needed to investigate the benefit of ibandronate on fracture rate reduction in this subset of patients. identifier: NCT01287533. ..
  3. Park J, Kim J, Moon J, Ahn E, Lee E, Lee E, et al. Altered lipoproteins in patients with systemic lupus erythematosus are associated with augmented oxidative stress: a potential role in atherosclerosis. Arthritis Res Ther. 2016;18:306 pubmed publisher
    ..001). Lipoproteins from SLE patients exhibited greater oxidative potential, which might contribute to accelerated atherosclerosis in SLE. ..
  4. Kang E, Lee S, Ascherman D, Lee Y, Lee E, Lee E, et al. Temporal relationship between cancer and myositis identifies two distinctive subgroups of cancers: impact on cancer risk and survival in patients with myositis. Rheumatology (Oxford). 2016;55:1631-41 pubmed publisher
    ..Multiple types of cancers showed elevated SIRs among CAM, but none among CNM. Given that cancer stages in CAM were far advanced at diagnosis, mortality risk was greater in patients with CAM. ..
  5. Lee J, Park J, Lee E, Lee E, Song Y. Circulating exosomes from patients with systemic lupus erythematosus induce an proinflammatory immune response. Arthritis Res Ther. 2016;18:264 pubmed
    ..846, p?=?0.008). The circulating exosomes are immunologically active and their levels correlate with disease activity in SLE patients. The circulating exosomes might serve as novel biomarkers of SLE disease activity. ..
  6. Kim J, Lee E, Lee E, Lee Y, Yoo H, Choi J, et al. Atorvastatin inhibits osteoclastogenesis by decreasing the expression of RANKL in the synoviocytes of rheumatoid arthritis. Arthritis Res Ther. 2012;14:R187 pubmed publisher
    ..These results suggest that atorvastatin inhibits osteoclastogenesis and bone destruction in RA patients. ..
  7. Kim J, Choi J, Park S, Yang S, Park J, Shin K, et al. Therapeutic effect of anti-C-X-C motif chemokine 10 (CXCL10) antibody on C protein-induced myositis mouse. Arthritis Res Ther. 2014;16:R126 pubmed publisher
    ..625 vs. anti-RVG1 treatment group, 1.25, P?=?0.007). CXCL10/CXCR3 expression was increased in the inflammation of CIM model and its blockade suppressed inflammation in muscle. ..
  8. Oh B, Suh D, Bae D, Ha N, Choi Y, Yoo H, et al. Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro. Arthritis Res Ther. 2017;19:154 pubmed publisher
    ..CKD-L increased CTLA-4 expression and the suppressive function of Treg cells. These results suggest that CKD-L may have a beneficial effect in the treatment of RA. ..
  9. Park J, Mecoli C, Alexanderson H, Regardt M, Christopher Stine L, Casal Domínguez M, et al. Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study. J Rheumatol. 2017;44:1683-1687 pubmed publisher
    ..At the next biennial OMERACT meeting, we aim to present and seek voting on a Myositis Preliminary PRO Core Set to enable ultimate measure selection and development. ..
  10. Go D, Shin K, Baek H, Kang S, Kang Y, Jun J, et al. Pivotal factors for successful withdrawal of nonsteroidal anti-inflammatory drugs in rheumatoid arthritis patients in remission or with low-disease activity. Clin Rheumatol. 2018;37:307-314 pubmed publisher
    ..014) and sustained effectiveness (OR 0.284, 95% CI 0.091-0.883, p = 0.030). Joint pain in RA patients in remission or with LDA can be well managed without NSAIDs, especially in those without swollen joints at the time of cessation. ..
  11. Kang E, Kim S, Park M, Choi J, Choi I, Kim M, et al. Behçet's disease risk association fine-mapped on the IL23R-IL12RB2 intergenic region in Koreans. Arthritis Res Ther. 2017;19:227 pubmed publisher
    ..BD susceptibility association was fine-mapped on the intergenic region between IL23R and IL12RB2 as marked by three correlated SNPs, rs1495965, rs1495966, and rs4655535. ..
  12. Lee S, Kang S, Kang E, Choi B, Masek Hammerman K, Syed J, et al. CXCL10/CXCR3 axis is associated with disease activity and the development of mucocutaneous lesions in patients with Behçet's disease. Sci Rep. 2017;7:14720 pubmed publisher
    ..These results suggest that the CXCL10/CXCR3 axis may contribute to the pathogenesis of BD. ..
  13. Kim H, Song Y. ANCA-associated vasculitis: report from Korea. Clin Exp Nephrol. 2013;17:708-711 pubmed publisher
    ..The data provided here may need to be confirmed in large-scale studies...
  14. Song Y, Kang E. Autoantibodies in rheumatoid arthritis: rheumatoid factors and anticitrullinated protein antibodies. QJM. 2010;103:139-46 pubmed publisher
    ..This review presents and discusses the current state of the art regarding RF and ACPA in RA. ..