Sun Ha Paek

Summary

Affiliation: Seoul National University
Country: Korea

Publications

  1. pmc A role of canonical transient receptor potential 5 channel in neuronal differentiation from A2B5 neural progenitor cells
    Hye Young Shin
    Department of Neurosurgery, Cancer Research Institute, Ischemic Hypoxic Disease Institute, College of Medicine, Seoul National University, Seoul, Korea
    PLoS ONE 5:e10359. 2010
  2. ncbi request reprint Brain-metastatic triple-negative breast cancer cells regain growth ability by altering gene expression patterns
    Youn Kyung Choi
    Cancer Research Institute, Ischemic Hypoxia Disease Institute, Seoul National University College of Medicine, 103 Daehak Ro, Jongno gu, Seoul, 110 799, South Korea Tel 82 220723993
    Cancer Genomics Proteomics 10:265-75. 2013
  3. doi request reprint The clinical impact of precise electrode positioning in STN DBS on three-year outcomes
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 327:25-31. 2013
  4. doi request reprint Electrode position determined by fused images of preoperative and postoperative magnetic resonance imaging and surgical outcome after subthalamic nucleus deep brain stimulation
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    Neurosurgery 63:925-36; discussion 936-7. 2008
  5. ncbi request reprint Sox2 expression in brain tumors: a reflection of the neuroglial differentiation pathway
    Ji Hoon Phi
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Am J Surg Pathol 32:103-12. 2008
  6. doi request reprint Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Chemotherapy 55:145-54. 2009
  7. pmc Recursive partitioning analysis of prognostic factors in WHO grade III glioma patients treated with radiotherapy or radiotherapy plus chemotherapy
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University, Seoul 110 744, Korea
    BMC Cancer 9:450. 2009
  8. ncbi request reprint Central neurocytoma: long-term outcomes of multimodal treatments and management strategies based on 30 years' experience in a single institute
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Neurosurgery 72:407-13; discussion 413-4. 2013
  9. doi request reprint Hearing outcomes after stereotactic radiosurgery for unilateral intracanalicular vestibular schwannomas: implication of transient volume expansion
    Young Hoon Kim
    Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam si, Korea
    Int J Radiat Oncol Biol Phys 85:61-7. 2013
  10. doi request reprint Gamma knife radiosurgery for skull base meningiomas: long-term radiologic and clinical outcome
    Jung Ho Han
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 72:1324-32. 2008

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. pmc A role of canonical transient receptor potential 5 channel in neuronal differentiation from A2B5 neural progenitor cells
    Hye Young Shin
    Department of Neurosurgery, Cancer Research Institute, Ischemic Hypoxic Disease Institute, College of Medicine, Seoul National University, Seoul, Korea
    PLoS ONE 5:e10359. 2010
    ..These results indicate that calcium regulation by TRPC5 would play a key role as a switch between proliferation and neuronal differentiation from NPCs...
  2. ncbi request reprint Brain-metastatic triple-negative breast cancer cells regain growth ability by altering gene expression patterns
    Youn Kyung Choi
    Cancer Research Institute, Ischemic Hypoxia Disease Institute, Seoul National University College of Medicine, 103 Daehak Ro, Jongno gu, Seoul, 110 799, South Korea Tel 82 220723993
    Cancer Genomics Proteomics 10:265-75. 2013
    ..BACKGROUD/AIM: Triple-negative breast cancer (TNBC) frequently metastasizes to the brain (BrM). However, genes responsible for BrM of TNBC are yet to be identified...
  3. doi request reprint The clinical impact of precise electrode positioning in STN DBS on three-year outcomes
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    J Neurol Sci 327:25-31. 2013
    ..We conclude that more accurate electrode positioning in the STN leads to better long-term outcomes in advanced PD patients following DBS...
  4. doi request reprint Electrode position determined by fused images of preoperative and postoperative magnetic resonance imaging and surgical outcome after subthalamic nucleus deep brain stimulation
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    Neurosurgery 63:925-36; discussion 936-7. 2008
    ..The aim of this study was to compare the surgical outcome of bilateral STN DBS with the electrode position estimated using fused magnetic resonance imaging...
  5. ncbi request reprint Sox2 expression in brain tumors: a reflection of the neuroglial differentiation pathway
    Ji Hoon Phi
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Am J Surg Pathol 32:103-12. 2008
    ..On the other hand, the aberrant coexpressions of Sox2 and of a neuronal marker were widely observed in glioblastomas, which reflects a disorganized differentiation pattern that characterizes highly malignant tumors...
  6. doi request reprint Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Chemotherapy 55:145-54. 2009
    ..We evaluated the benefit of preradiation chemotherapy with ACNU (nimustine) and CDDP (cisplatin) in patients with newly diagnosed glioblastoma by retrospective analysis...
  7. pmc Recursive partitioning analysis of prognostic factors in WHO grade III glioma patients treated with radiotherapy or radiotherapy plus chemotherapy
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University, Seoul 110 744, Korea
    BMC Cancer 9:450. 2009
    ..To our knowledge, this is the first study to address the results of RPA specifically for WHO grade III gliomas...
  8. ncbi request reprint Central neurocytoma: long-term outcomes of multimodal treatments and management strategies based on 30 years' experience in a single institute
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Neurosurgery 72:407-13; discussion 413-4. 2013
    ..A thorough investigation of the long-term outcomes of central neurocytoma (CN) after different treatments is required to establish optimal management strategies...
  9. doi request reprint Hearing outcomes after stereotactic radiosurgery for unilateral intracanalicular vestibular schwannomas: implication of transient volume expansion
    Young Hoon Kim
    Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam si, Korea
    Int J Radiat Oncol Biol Phys 85:61-7. 2013
    ..We evaluated the prognostic factors for hearing outcomes after stereotactic radiosurgery (SRS) for unilateral sporadic intracanalicular vestibular schwannomas (IC-VSs) as a clinical homogeneous group of VSs...
  10. doi request reprint Gamma knife radiosurgery for skull base meningiomas: long-term radiologic and clinical outcome
    Jung Ho Han
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 72:1324-32. 2008
    ..To analyze the long-term outcomes in patients with skull base meningiomas (SBMNGs) treated with Gamma Knife radiosurgery (GKRS)...
  11. doi request reprint Radiosurgery for atypical and anaplastic meningiomas: histopathological predictors of local tumor control
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Stereotact Funct Neurosurg 90:316-24. 2012
    ..We investigated the radiosurgical outcomes of patients with nonbenign meningiomas retrospectively and sought to identify prognostic factors for local tumor control after radiosurgery with an emphasis on histopathology...
  12. ncbi request reprint Endogenous neurogenesis and neovascularization in the neocortex of the rat after focal cerebral ischemia
    Hye Young Shin
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosci Res 86:356-67. 2008
    ..Endogenous neurogenesis and neovascularization were substantially activated and occurred in close proximity to one other in the ipsilateral neocortex of the ischemic rat brain...
  13. doi request reprint Radiosurgery for brain metastasis from advanced gastric cancer
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Bundang gu, Seongnam si, Gyeonggi do 463 707, Korea
    Acta Neurochir (Wien) 152:605-10. 2010
    ..We retrospectively evaluated the survival of patients with brain metastases from advanced gastric cancer (AGC) after radiosurgery (RS)...
  14. pmc Electrode position and the clinical outcome after bilateral subthalamic nucleus stimulation
    Sun Ha Paek
    Movement Disorder Center and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 26:1344-55. 2011
    ..Our findings suggest that the better symptom relief including speech with a reduced LEDD is expected in the patients whose electrodes are accurately positioned in both STN...
  15. doi request reprint Fusion image-based programming after subthalamic nucleus deep brain stimulation
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea
    World Neurosurg 75:517-24. 2011
    ..To propose fusion image-based programming to adjust patients with advanced Parkinson disease (PD) effectively after subthalamic nucleus (STN) deep brain stimulation (DBS)...
  16. doi request reprint Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University, Seoul, Korea
    Neuropathology 29:443-9. 2009
    ..529). The most noteworthy explanation for the result is that the synergistic antitumor effects of ACNU and cisplatin resulting from inactivation of MGMT by cisplatin in MGMT active tumors offset the drug resistance...
  17. doi request reprint Protective role of COMP-Ang1 in ischemic rat brain
    Hye Young Shin
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosci Res 88:1052-63. 2010
    ..Taken together, COMP-Ang1 reduced infarct volume and consequently attenuated post-ischemic neurological deficits through enhanced angiogenesis and increased viable cell mass of neuronal cells...
  18. doi request reprint Radiosurgery for para-IAC meningiomas: the effect of radiation dose to the cochlea on hearing outcome
    Young Hoon Kim
    Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam si, Korea
    Int J Radiat Oncol Biol Phys 84:675-80. 2012
    ..This study was performed to assess the radiosurgical results of meningiomas extending into the internal acoustic canal (para-IAC meningiomas), with a particular focus on the effect of radiation dose to the cochlea on hearing outcome...
  19. doi request reprint Surgically treated brain tumors: a retrospective case series of 10,009 cases at a single institution
    Young Hoon Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    World Neurosurg 76:555-63. 2011
    ..To evaluate the chronologic trends in brain tumor surgery at a single institution over 53 years (1957-2009)...
  20. doi request reprint Early significant tumor volume reduction after radiosurgery in brain metastases from renal cell carcinoma results in long-term survival
    Wook Ha Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 82:1749-55. 2012
    ..To retrospectively evaluate survival of patients with brain metastasis from renal cell carcinoma (RCC) after radiosurgery...
  21. ncbi request reprint Radiosurgery for central neurocytoma: long-term outcome and failure pattern
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, 101 Daehangno, Jongno gu, Seoul, 110 744, Korea
    J Neurooncol 115:505-11. 2013
    ..However, long-term radiological follow-up is mandatory. In particular, more careful consideration during margin delineation and planning procedure is required in the secondary GKRS group...
  22. doi request reprint Radiosurgery for large brain metastases
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Int J Radiat Oncol Biol Phys 83:113-20. 2012
    ..To determine the efficacy and safety of radiosurgery in patients with large brain metastases treated with radiosurgery...
  23. doi request reprint Is it effective to raise the irradiation dose from 80 to 85 Gy in gamma knife radiosurgery for trigeminal neuralgia?
    Yong Hwy Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, South Korea
    Stereotact Funct Neurosurg 88:169-76. 2010
    ..In order to assess the effect of raising gamma knife radiosurgery (GKS) doses from 80 to 85 Gy for the treatment of trigeminal neuralgia (TN), the authors analyzed the outcomes of GKS in each group...
  24. doi request reprint The risk factors of symptomatic communicating hydrocephalus after stereotactic radiosurgery for unilateral vestibular schwannoma: the implication of brain atrophy
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Int J Radiat Oncol Biol Phys 84:937-42. 2012
    ..To identify the effect of brain atrophy on the development of symptomatic communicating hydrocephalus (SCHCP) after stereotactic radiosurgery (SRS) for sporadic unilateral vestibular schwannomas (VS)...
  25. ncbi request reprint The clinicopathologic values of the molecules associated with the main pathogenesis of the glioblastoma
    Bomi Kim
    Department of Pathology, Inje University, College of Medicine, Busan, Republic of Korea
    J Neurol Sci 294:112-8. 2010
    ..05). Longer survival (survival length, > or =3 years) was statistically less frequent in the patients in the EGFR FISH-positive group (p=0.031)...
  26. doi request reprint Effects of human neural stem cell transplantation in canine spinal cord hemisection
    Seung Hoon Lee
    Department of Neurology, Seoul National University and Seoul National University Hospital, Seoul, Korea
    Neurol Res 31:996-1002. 2009
    ..In the present work, the authors sought to determine whether the transplantation of human NSCs improves functional outcome in a canine SCI model and whether transplanted NSCs survive and differentiate...
  27. doi request reprint Hearing preservation in patients with unilateral vestibular schwannoma who undergo stereotactic radiosurgery: Reinterpretation of the auditory brainstem response
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Cancer 118:5441-7. 2012
    ....
  28. doi request reprint Stereotactic radiosurgery for brain metastases from hepatocellular carcinoma
    Jung Ho Han
    Department of Neurosurgery, Seoul National University Bundang Hospital, Gyeonggi Do, Seongnam, Korea
    J Neurooncol 115:45-51. 2013
    ..010). The prognosis of patients with brain metastases from HCC is dismal even with the modern technology of radiosurgery. The marginal dose prescribed should be reevaluated to improve upon the current poor local control rates. ..
  29. doi request reprint The benefit of subthalamic deep brain stimulation for pain in Parkinson disease: a 2-year follow-up study
    Han Joon Kim
    Department of Neurology, Movement Disorder Center, Neuroscience Research Institute, College of Medicine, Seoul National University Hospital, Seoul, Korea
    Neurosurgery 70:18-23; discussion 23-4. 2012
    ..In a previous study, we showed that subthalamic deep brain stimulation (STN DBS) improves pain as well as motor symptoms 3 months after surgery in PD patients...
  30. doi request reprint Gamma Knife stereotactic radiosurgery for intracranial hemangiopericytomas
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurooncol 99:115-22. 2010
    ..Close radiological follow-up is also necessary for early detection of small recurrent lesions...
  31. doi request reprint Tissue expression of manganese superoxide dismutase is a candidate prognostic marker for glioblastoma
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Oncology 77:178-81. 2009
    ..Characterization of a rare subgroup of glioblastoma patients who survive for more than 3 years (long-term survival glioblastoma, LTSGBL, patients) may be helpful to identify prognostic factors...
  32. doi request reprint Clinical and neuroimaging outcome of cerebral arteriovenous malformations after Gamma Knife surgery: analysis of the radiation injury rate depending on the arteriovenous malformation volume
    Jung Ho Han
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosurg 109:191-8. 2008
    ....
  33. ncbi request reprint Gamma knife radiosurgery for central neurocytoma: primary and secondary treatment
    Chae Yong Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Cancer 110:2276-84. 2007
    ..The authors retrospectively reviewed long-term outcomes of 13 patients with CN treated with GK SRS...
  34. doi request reprint The enigma of bifocal germ cell tumors in the suprasellar and pineal regions: synchronous lesions or metastasis?
    Ji Hoon Phi
    Division of Pediatric Neurosurgery, Seoul National University Children s Hospital, Seoul, Korea
    J Neurosurg Pediatr 11:107-14. 2013
    ..Bifocal GCTs may be caused by synchronous tumors or by metastatic spread of tumor cells from one site to the other. The prognosis associated with bifocal GCTs has also been a cause of concern...
  35. doi request reprint Radiotherapy followed by adjuvant temozolomide with or without neoadjuvant ACNU-CDDP chemotherapy in newly diagnosed glioblastomas: a prospective randomized controlled multicenter phase III trial
    Il Han Kim
    Department of Radiation Oncology, Cancer Research Institute, Seoul National University Hospital, 28 Yeongeon dong, Jongno gu, Seoul 110 744, Korea
    J Neurooncol 103:595-602. 2011
    ..Future studies should aim to identify a subpopulation at reduced risk for ACNU-CDDP toxicity so that the potential of this protocol can be realized...
  36. ncbi request reprint Long-term outcome of conventional radiation therapy for central neurocytoma
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurooncol 90:25-30. 2008
    ..Conventional RT seemed to effectively control residual CN after surgery. However, more sophisticated radiation techniques should be applied to minimize the late sequela...
  37. doi request reprint Bilateral subthalamic deep brain stimulation in Parkinson disease patients with severe tremor
    Han Joon Kim
    Department of Neurology, Movement Disorder Center, Neuroscience Research Institute, BK21, College of Medicine, Seoul National University Hospital, Seoul, Korea
    Neurosurgery 67:626-32; discussion 632. 2010
    ..Previous studies have shown that subthalamic nucleus (STN) deep brain stimulation (DBS) improves tremor in Parkinson disease (PD). However, the patients included in those studies were unselected for tremor severity...
  38. doi request reprint Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model
    Keun Tae Cho
    Department of Neurosurgery, Dongguk University Seoul and Dongguk University Ilsan Hospital, Goyang, Republic of Korea
    J Neurol Surg A Cent Eur Neurosurg 73:132-41. 2012
    ..Taken together, new therapeutic strategies other than the simple addition of radiosurgery deserve to be investigated in the interest of enhancing the effects of radiosurgery...
  39. doi request reprint Efficacy of corticosteroids in hearing preservation after radiosurgery for vestibular schwannoma: a prospective study
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    Stereotact Funct Neurosurg 89:25-33. 2011
    ..We prospectively investigated the efficacy of corticosteroid medication in salvaging acute hearing deterioration after radiosurgery for vestibular schwannoma (VS) and analyzed prognostic factors for hearing preservation...
  40. ncbi request reprint The role of adjuvant radiotherapy in atypical meningioma
    Hae Jin Park
    Department of Radiation Oncology, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak Ro, Jongno gu, Seoul, 110 799, Korea
    J Neurooncol 115:241-7. 2013
    ..Our results may contribute to the routine use of ART, especially after incomplete resection, until the outcomes of ongoing prospective trials are available...
  41. ncbi request reprint Development of dose-volume relation model for gamma knife surgery of non-skull base intracranial meningiomas
    Hyun Tai Chung
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 74:1027-32. 2009
    ..To provide a dose-volume relationship for gamma knife surgery (GKS) of non-skull base intracranial meningiomas...
  42. ncbi request reprint Surgically treated tuberculum sellae and diaphragm sellae meningiomas: the importance of short-term visual outcome
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Neurosurgery 59:238-43; discussion 238-43. 2006
    ..Prognostic and diagnostic values of short- and long-term postoperative visual outcome and etiology for postoperative visual deterioration are discussed with special attention...
  43. ncbi request reprint Gamma Knife surgery and trigeminal schwannoma: is it possible to preserve cranial nerve function?
    Ji Hoon Phi
    Department of Neurosurgery, Seoul National University College of Medicine, Korea
    J Neurosurg 107:727-32. 2007
    ..The conditions associated with the development of cranial neuropathies after radiosurgery were scrutinized...
  44. doi request reprint Longitudinal analysis of visual outcomes after surgical treatment of adult craniopharyngiomas
    Young Hoon Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Neurosurgery 71:715-21. 2012
    ..Craniopharyngiomas (CRPs) often cause visual deterioration (VD) due to the close vicinity of the optic apparatus...
  45. ncbi request reprint Microhemorrhage, a possible mechanism for cyst formation in vestibular schwannomas
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Korea
    J Neurosurg 105:576-80. 2006
    ..Little is known, however, about the mechanism of cyst formation. In this study the authors compared neuroimaging and histological characteristics of cystic with solid VS to determine the pathogenesis of the cystic subgroup...
  46. ncbi request reprint Long-term outcome of trigeminal neurinomas with modified classification focusing on petrous erosion
    Ho Shin Gwak
    Department of Neurosurgery, Korea Cancer Center Hospital, Seoul, South Korea
    Surg Neurol 60:39-48; discussion 48. 2003
    ..Modified classification based on the tumor distribution over petrous ridge is suggested to select the optimal surgical approach and to predict the outcome...
  47. doi request reprint Long-term outcome of gamma knife radiosurgery for treatment of typical trigeminal neuralgia
    Jung Ho Han
    Department of Neurosurgery, Seoul National University College of Medicine, 28 Yeongeon dong, Chongno Gu, Seoul, Korea
    Int J Radiat Oncol Biol Phys 75:822-7. 2009
    ..To analyze the long-term outcomes of patients with typical trigeminal neuralgia treated with gamma knife radiosurgery (GKRS)...
  48. ncbi request reprint Stereotactic radiosurgery for cavernous sinus hemangiomas
    Sang Woo Song
    Department of Neurosurgery, Seoul National University College of Medicine, 101 Daehang ro Jongno gu, Seoul, 110 744, Korea
    J Neurooncol 118:163-8. 2014
    ..7%) cranial nerves and partial remission in two (14.3%). There were no radiation-induced neuropathies or complications during the follow-up period. SRS appears to be an effective and safe treatment modality for the management of CSHs...
  49. doi request reprint Acute brain reaction to DBS electrodes after deep brain stimulation: chronological observation
    Jin Wook Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, 110 744, Korea
    Acta Neurochir (Wien) 155:2365-71; discussion 2371. 2013
    ..The aim of this study was to clarify this rare phenomenon using chronological observations and to suggest a feasible mechanism...
  50. pmc Early experience of pre- and post-contrast 7.0T MRI in brain tumors
    Seung Leal Paek
    Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 28:1362-72. 2013
    ..Further studies are needed to develop refined MRI protocols for better images of brain tumors located in the skull base, parasellar, and adjacent major cerebrovascular structures. ..
  51. ncbi request reprint Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson's disease
    Han Joon Kim
    Department of Neurology and Movement Disorder Center, Parkinson Study Group, and Neuroscience Research Institute, College of Medicine, Seoul National University, 28 Yongon Dong, Chongno Gu, Seoul, 110 744, Korea
    J Neurol 261:1090-6. 2014
    ..In addition, preoperative PD-MCI was a risk factor for dementia after STN DBS. ..
  52. ncbi request reprint Investigation of molecular factors associated with malignant transformation of oligodendroglioma by proteomic study of a single case of rapid tumor progression
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, 28 Yeongeon dong, Jongno gu, Seoul 110 744, South Korea
    J Cancer Res Clin Oncol 134:255-62. 2008
    ....
  53. ncbi request reprint The selection of the optimal therapeutic strategy for petroclival meningiomas
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul 110 744, South Korea
    Surg Neurol 66:160-5; discussion 165-6. 2006
    ..Broad experience with the management of petroclival meningiomas was analyzed to optimize therapeutic strategy...
  54. doi request reprint Pulmonary resection in patients with nonsmall-cell lung cancer treated with gamma-knife radiosurgery for synchronous brain metastases
    Seung Yeob Yang
    Department of Neurosurgery, Dongguk University International Hospital, Gyeonggi Do, Korea
    Cancer 112:1780-6. 2008
    ..The aim of the current study was to determine whether a pulmonary resection and gamma-knife radiosurgery (GKRS) protocol is superior to GKRS alone in selected patients with stage IV nonsmall-cell lung cancer (NSCLC)...
  55. ncbi request reprint Therapeutic strategy for large vestibular schwannomas
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Chongno Gu, Seoul, Korea
    J Neurooncol 77:167-71. 2006
    ..NTR or R-STR with adjuvant radiosurgery might be acceptable therapeutic options for large VS in terms of achieving good tumor control and functional preservation of facial nerve...
  56. doi request reprint Is MRI a reliable tool to locate the electrode after deep brain stimulation surgery? Comparison study of CT and MRI for the localization of electrodes after DBS
    Ji Yeoun Lee
    Department of Neurosurgery, Seoul National University College of Medicine, Jongno gu, Seoul, South Korea
    Acta Neurochir (Wien) 152:2029-36. 2010
    ..Under the hypothesis that MRI is not adequate for evaluation of electrode position after deep brain stimulation, this study is aimed at validating the accuracy of MRI in electrode localization in comparison with CT scan...
  57. doi request reprint Comparison of electrode location between immediate postoperative day and 6 months after bilateral subthalamic nucleus deep brain stimulation
    Yong Hwy Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Jongno gu, South Korea
    Acta Neurochir (Wien) 152:2037-45. 2010
    ..We compared the electrode positions of subthalamic nucleus (STN) deep brain stimulation (DBS) estimated at the immediate postoperative period with those estimated 6 months after surgery...
  58. doi request reprint Intracranial capillary hemangioma: extra-axial tumorous lesions closely mimicking meningioma
    Ji Hoon Phi
    Division of Pediatric Neurosurgery, Seoul National University Children s Hospital, 101 Daehak Ro, Jongno gu, Seoul, 110 744, Republic of Korea
    J Neurooncol 109:177-85. 2012
    ..Capillary hemangioma should be considered in the diagnosis of extra-axial, contrast-enhancing lesions, especially in children and adolescents...
  59. pmc Primary culture of central neurocytoma: a case report
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University, Seoul, Korea
    J Korean Med Sci 25:798-803. 2010
    ..It is suggested that CN has the characteristics of neuronal stem cells and potential to differentiate into mature neuron and glial cells depending on the environmental cue...
  60. pmc The experience of ligation of transverse or sigmoid sinus in surgery of large petroclival meningiomas
    Sung Kyun Hwang
    Department of Neurosurgery, College of Medicine Seoul National University and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 17:544-8. 2002
    ..Our observation suggests that the transverse or sigmoid sinus ligation is tolerable to patients who show the drainage patterns of type A, type B, and type C, if the test clamping proves to be safe...
  61. doi request reprint Young-onset multiple system atrophy
    Han Joon Kim
    Department of Neurology, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
    J Neurol Sci 319:168-70. 2012
    ..Multiple system atrophy (MSA) rarely begins before the age of 40 and detailed descriptions of young-onset MSA are lacking...
  62. doi request reprint Brain metastasis from renal cell carcinoma
    Yong Hwy Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Prog Neurol Surg 25:163-75. 2012
    ..Therefore, SRS must be emphasized in the management of brain metastasis from RCC and individual various combined treatment strategies could be suggested...
  63. doi request reprint Radiosurgical treatment of vestibular schwannomas in patients with neurofibromatosis type 2: tumor control and hearing preservation
    Ji Hoon Phi
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea
    Cancer 115:390-8. 2009
    ..The authors investigated the radiologically proven tumor control rate after gamma knife radiosurgery. The factors that affect tumor control and serviceable hearing preservation were analyzed...
  64. doi request reprint Parkin mutation and deep brain stimulation outcome
    Hee Jin Kim
    Department of Neurology, Konkuk University Medical Center, Seoul, Republic of Korea
    J Clin Neurosci 21:107-10. 2014
    ..The therapeutic effect of DBS did not differ between patients with and without parkin mutations. ..
  65. doi request reprint Radiosurgery for unruptured cerebral arteriovenous malformations: long-term seizure outcome
    Seung Yeob Yang
    Department of Neurosurgery, Dongguk University Graduate School, Seoul, Korea
    Neurology 78:1292-8. 2012
    ..This study aimed to determine the effect of radiosurgery on seizure outcome depending on AVM obliteration and on the development of new seizure in patients with AVM...
  66. doi request reprint Great hospitals of Asia: the Department of Neurosurgery at Seoul National University College of Medicine
    Dong Gyu Kim
    Department of Neurosurgery, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Korea
    World Neurosurg 75:397-406. 2011
    ..This article traces the clinical, academic, and scientific development of the department, its present activities, and its future direction...
  67. doi request reprint Clinical experiences with spontaneous intracranial hypotension: a proposal of a diagnostic approach and treatment
    Sang Hoon Yoon
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, South Korea
    Clin Neurol Neurosurg 113:373-9. 2011
    ..We analyzed our clinical experience with patients with intracranial hypotension and developed a strategic model for the diagnosis mainly using Radioisotope (RI) cisternography and treatment of spontaneous intracranial hypotension (SIH)...
  68. doi request reprint Effect of deep brain stimulation on pain in Parkinson disease
    Han Joon Kim
    Department of Neurology, Movement Disorder Center, and Neuroscience Research Institute, BK21, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
    J Neurol Sci 310:251-5. 2011
    ..In this article we review reports on the improvement of pain in PD by surgical interventions such as subthalamic deep brain stimulation (STN DBS), and discuss the possible mechanisms by which STN DBS improves pain in PD...
  69. doi request reprint Cortico-muscular coherence increases with tremor improvement after deep brain stimulation in Parkinson's disease
    Hame Park
    MEG Center, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongno gu, Seoul 110 744, Korea
    Neuroreport 20:1444-9. 2009
    ..This suggests that deep brain stimulation resulted in better cortico-muscular coordination...
  70. pmc STN DBS of Advanced Parkinson's Disease Experienced in a Specialized Monitoring Unit with a Prospective Protocol
    Ji Yeoun Lee
    Department of Neurosurgery, Cancer Research Institute, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Korean Neurosurg Soc 44:26-35. 2008
    ..This study aimed to assess the short-term outcome of STN stimulation for patients with advanced PD evaluated in a 24-hour monitoring unit for movement disorder (MUMD) using a prospective protocol...
  71. ncbi request reprint Molecular characterization of the NF2 gene in Korean patients with neurofibromatosis type 2: a report of four novel mutations
    Moon Woo Seong
    Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea
    Korean J Lab Med 30:190-4. 2010
    ..In this study, we conducted a comprehensive mutational analysis in 7 Korean NF2 patients by performing direct sequencing and gene-dosage assessment...
  72. pmc Recurrent juvenile nasopharyngeal angiofibroma treated with gamma knife surgery
    Chul Kee Park
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Medical Research Center, Seoul National University Hospital, Chongno Gu, Seoul, Korea
    J Korean Med Sci 21:773-7. 2006
    ..Usually JNA can be exclusively diagnosed by radiological study alone. So this report of successful treatment of JNA with GKS may provide an important clue for the novel indication of GKS...
  73. ncbi request reprint Simple measurement of spinal cord evoked potential: a valuable data source in the rat spinal cord injury model
    Jong Pil Park
    Department of Neurosurgery, Seoul National University College of Medicine, 28 Yeongeon dong, Jongno gu, Seoul 110 744, Korea
    J Clin Neurosci 14:1099-105. 2007
    ..Complete destruction of pyramidal tracts in both dorsal and ventral fibers was essential for long-term impairment of locomotion...
  74. doi request reprint Data management system in a movement disorder center: technical report
    Sun Ha Paek
    Department of Neurosurgery, Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Stereotact Funct Neurosurg 88:216-23. 2010
    ..We designed a specialized monitoring unit and data management system with systematic storage and easy access for a deep brain stimulation program of patients with movement disorders...
  75. ncbi request reprint Phase II study of chemotherapy with ACNU plus cisplatin followed by cranial irradiation in patients with newly diagnosed glioblastoma multiforme
    In Sil Choi
    Department of Internal Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
    J Neurooncol 60:171-6. 2002
    ....
  76. ncbi request reprint Olfactory neuroblastomas: survival rate and prognostic factor
    Sung Kyun Hwang
    Department of Neurosurgery, Ewha Womans University College of Medicine, Seoul, Korea
    J Neurooncol 59:217-26. 2002
    ....
  77. pmc Long-term Outcomes of Gamma Knife Stereotactic Radiosurgery of Vestibular Schwannomas
    Kang Min Kim
    Department of Neurosurgery, Seoul National University, College of Medicine, Seoul, Korea
    J Korean Neurosurg Soc 42:286-92. 2007
    ..We evaluated the tumor control rate, patterns of tumor volume change and preservation of hearing following low-dose radiation for vestibular schwannomas in a homogeneous cohort group in which the mean marginal dose was 12 Gy...
  78. doi request reprint Galectin-3: a useful biomarker for differential diagnosis of brain tumors
    Sung Hye Park
    Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
    Neuropathology 28:497-506. 2008
    ....
  79. pmc Clinical application of 7.0 T magnetic resonance images in Gamma Knife radiosurgery for a patient with brain metastases
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University Hospital, Cancer Research Institute, Ischemic Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea
    J Korean Med Sci 26:839-43. 2011
    ..Furthermore 7.0 T MR images provide better visualization of brain tumors without image distortion in comparison to 1.5 T MR images...
  80. pmc Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival
    Sang Soo Kang
    Center for Neural Science, Future Fusion Technology Laboratory, Seoul National University, Seoul, Republic of Korea
    Cancer Res 70:1173-83. 2010
    ..These findings suggest IP(3)R3 as a novel therapeutic target and identify caffeine as a possible adjunct therapy to slow invasive growth of glioblastoma...
  81. ncbi request reprint Supratentorial primitive neuroectodermal tumors in adults
    Dong Gyu Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Republic of Korea
    J Neurooncol 60:43-52. 2002
    ..Intratumoral calcifications and the Ki-67 labelling index might be prognostic factors, however, it should be considered that the sample size is too small and not all patients were evaluated...
  82. ncbi request reprint Patient-specific embryonic stem cells derived from human SCNT blastocysts
    Woo Suk Hwang
    College of Veterinary Medicine, Seoul National University, Seoul 151 742, Korea
    Science 308:1777-83. 2005
    ..Before clinical use of these cells can occur, preclinical evidence is required to prove that transplantation of differentiated NT-hESCs can be safe, effective, and tolerated...
  83. ncbi request reprint Gamma knife surgery of superficially located meningioma
    Dong Gyu Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosurg 102:255-8. 2005
    ..The authors analyzed tumor control rates and complications in patients with superficially located meningiomas after gamma knife surgery (GKS)...
  84. ncbi request reprint Expression of Sox2 in mature and immature teratomas of central nervous system
    Ji Hoon Phi
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Mod Pathol 20:742-8. 2007
    ..Since Sox2 is strongly expressed in the primitive neuroepithelial tissues of central nervous system immature teratomas, it may be a useful biomarker for the diagnosis and quantitative grading of central nervous system immature teratomas...
  85. doi request reprint Non-Hodgkin lymphoma of the cranial vault with retrobulbar metastasis mimicking a subacute subdural hematoma: case report
    Sang Hoon Yoon
    Department of Neurosurgery Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
    J Neurosurg 108:1018-20. 2008
    ..The lesion in this case was misdiagnosed as a subdural hematoma, and shows the importance of including lymphoma in the differential diagnosis of subdural mass lesions...
  86. doi request reprint Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells
    Jung Eun Gil
    Laboratory of Stem Cell Biology, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
    FEBS Lett 583:561-7. 2009
    ..These results support the beneficial effect of VN on oligodendrocytic differentiation of hESCs...
  87. ncbi request reprint Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University, Seoul, South Korea
    Neurosurgery 56:1021-34; discussion 1021-34. 2005
    ..Patients with brain metastases were analyzed retrospectively to assess the risks and benefits of surgery with modern neurosurgical techniques, including image guidance coupled as indicated with corticography...
  88. ncbi request reprint Chromosome 1p and 19q status and p53 and p16 expression patterns as prognostic indicators of oligodendroglial tumors: a clinicopathological study using fluorescence in situ hybridization
    Yoon Kyung Jeon
    Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
    Neuropathology 27:10-20. 2007
    ..011). Therefore, in oligodendrogliomas, the absence of the combined deletion of 1p and 19q and the aberrant expression of p53 or loss of p16 could be used as poor prognostic markers...
  89. ncbi request reprint Recurrence of Cushing's disease after primary transsphenoidal surgery in a university hospital in Korea
    Jung Hee Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Endocr J 59:881-8. 2012
    ..Preoperative serum cortisol level and pathologic confirmation of an adenoma may have a predictive value for recurrence of CD after TSS...
  90. doi request reprint Functional neuroimaging of the 6-OHDA lesion rat model of Parkinson's disease
    Dong Pyo Jang
    Department of Biomedical Engineering, Hanyang University, Seoul, Republic of Korea
    Neurosci Lett 513:187-92. 2012
    ..In conclusion, In vivo cerebral mapping of the 6-OHDA-lesioned rats using [(18)F]-FDG PET showed correspondence at the functional levels to the cortico-subcortical network impairment observed in PD patients...
  91. ncbi request reprint Bo Sung Sim (1924-2001): a pioneer of neurosurgery in Korea
    Dong Gyu Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosurg 105:494-7. 2006
    ..Sim was a true neurosurgeon-a teacher, a scientist, and a superb pioneer in Korean neurosurgery...
  92. pmc Atypical extraventricular neurocytoma
    Hyunho Choi
    Department of Neurosurgery, Cancer Research Institute, Ischemic Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea
    J Korean Neurosurg Soc 50:381-4. 2011
    ..We emphasize that EVN should be included in the differential diagnosis of oligodendroglioma...
  93. pmc Development of a stereotactic device for gamma knife irradiation of small animals
    Hyun Tai Chung
    Department of Neurosurgery, Seoul National University, College of Medicine, Seoul, Korea
    J Korean Neurosurg Soc 43:26-30. 2008
    ..The authors developed a stereotactic device for irradiation of small animals with Leksell Gamma Knife(R) Model C. Development and verification procedures were described in this article...
  94. ncbi request reprint Correlation of clinical and biological parameters with peritumoral edema in meningioma
    Sun Ha Paek
    Department of Neurosurgery, Clinical Research Institute of Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
    J Neurooncol 60:235-45. 2002
    ..The expressions of MMP-2, -9, and TIMPs as well as VEGF in meningioma suggests that they are strongly related with the presence of PTE in meiningiomas, and that they might play the important role in the formation of PTE in meningiomas...
  95. ncbi request reprint Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exercise
    Dae Yul Kim
    Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Neurosci Res 58:164-75. 2007
    ..In addition, it was found that cell inoculation should be replaced by a noninvasive procedure...
  96. ncbi request reprint Aggressive vestibular schwannomas with postoperative rapid growth: clinicopathological analysis of 15 cases
    Sung Kyun Hwang
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Neurosurgery 51:1381-90; discussion 1390-1. 2002
    ..Our objective was to investigate the clinicopathological characteristics of these tumors and to elucidate factors that can predict rapid regrowth or recurrence after surgical resection...
  97. ncbi request reprint Hearing preservation after gamma knife stereotactic radiosurgery of vestibular schwannoma
    Sun Ha Paek
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Korea
    Cancer 104:580-90. 2005
    ....
  98. ncbi request reprint Linear accelerator radiosurgery for central neurocytoma: a case report
    Chae Yong Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Neurooncol 61:249-54. 2003
    ..LINAC radiosurgery is suggested to be a good treatment modality for residual or recurrent central neurocytoma...
  99. ncbi request reprint Surgical treatment of symptomatic Rathke cleft cysts: clinical features and results with special attention to recurrence
    Jeong Eun Kim
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    J Neurosurg 100:33-40. 2004
    ..Rathke cleft cysts (RCCs) are rarely symptomatic. The purpose of this study was to clarify the clinical, neuroimaging, surgical, and pathological features of symptomatic RCCs with special attention to their recurrence...
  100. ncbi request reprint Clinicopathological study of seven cases of symptomatic supratentorial subependymoma
    So Hyang Im
    Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Neurooncol 61:57-67. 2003
    ..For symptomatic supratentorial subependymomas, gross total resection is the treatment of choice and radiation has little effect on tumor control...