Research Topics

Genomes and Genes


Chang Kyu Lee


Affiliation: Seoul National University
Country: Korea


  1. Hwang J, Oh J, Lee D, Choi K, Park C, Lee C. Identification and differential expression patterns of porcine OCT4 variants. Reproduction. 2015;149:55-66 pubmed publisher
  2. Kim E, Hwang S, Yoo H, Yoon J, Jeon Y, Kim H, et al. Putative embryonic stem cells derived from porcine cloned blastocysts using induced pluripotent stem cells as donors. Theriogenology. 2016;85:601-16 pubmed publisher
    ..This is the first study to establish and characterize the iPSC-derived putative ESC lines and compare them with other lines derived from different origins in pigs. ..
  3. Hwang J, Oh J, Park C, Lee D, Lee C. Dosage compensation of X-chromosome inactivation center-linked genes in porcine preimplantation embryos: Non-chromosome-wide initiation of X-chromosome inactivation in blastocysts. Mech Dev. 2015;138 Pt 3:246-55 pubmed publisher
    ..In addition, a few XIC-linked genes would likely achieve dosage compensation, but XCI would not be completed in porcine blastocysts. ..
  4. Uh K, Park C, Choi K, Park J, Jeong Y, Roh S, et al. Analysis of imprinted IGF2/H19 gene methylation and expression in normal fertilized and parthenogenetic embryonic stem cells of pigs. Anim Reprod Sci. 2014;147:47-55 pubmed publisher
    ..Therefore, with their uni-parental genotype, the pluripotent differentiation potentials of PG ES cells could be a valuable tool for understanding genomic imprinting in embryonic development. ..