Research Topics

Genomes and Genes

Kook Hyung Kim


Affiliation: Seoul National University
Country: Korea


  1. Alazem M, Tseng K, Chang W, Seo J, Kim K. Elements Involved in the Rsv3-Mediated Extreme Resistance against an Avirulent Strain of Soybean Mosaic Virus. Viruses. 2018;10: pubmed publisher
    ..The results also suggest that suppression of the JA pathway in the case of G5H is important for the Rsv3-mediated ER. ..
  2. Tran P, Choi H, Choi D, Kim K. Molecular characterization of Pvr9 that confers a hypersensitive response to Pepper mottle virus (a potyvirus) in Nicotiana benthamiana. Virology. 2015;481:113-23 pubmed publisher
    ..The 5' upstream region of Pvr9 from cultivar CM334 had higher transcription activity than the region from cultivar Floral Gem. The cultivars CM334 and Floral Gem had non-functional Pvr9 homologs with loss-of-function mutations. ..
  3. Son M, Choi H, Kim K. Specific binding of Fusarium graminearum Hex1 protein to untranslated regions of the genomic RNA of Fusarium graminearum virus 1 correlates with increased accumulation of both strands of viral RNA. Virology. 2016;489:202-11 pubmed publisher
    ..These results indicate that the FgHex1 functions in the synthesis of both strands of FgV1 RNA and therefore in FgV1 replication probably by specifically binding to the FgV1 genomic RNA. ..
  4. Kim H, Cho W, Lian S, Kim K. Identification of residues or motif(s) of the rice stripe virus NS3 protein required for self-interaction and for silencing suppressor activity. Virus Res. 2017;235:14-23 pubmed publisher
    ..These results suggest that RSV requires NS3 self-interaction to suppress RNA silencing and to thereby counter host defenses. ..
  5. Yu J, Lee K, Cho W, Park J, Kim K. Differential Contribution of RNA Interference Components in Response to Distinct Fusarium graminearum Virus Infections. J Virol. 2018;92: pubmed publisher
    ..graminearum developed a more complex and robust RNA silencing system against mycoviruses and that FgDICER-1 and FgDICER-2 and FgAGO-1 and FgAGO-2 had redundant roles in antiviral RNA silencing. ..
  6. Cho W, Yu J, Lee K, Son M, Min K, Lee Y, et al. Genome-wide expression profiling shows transcriptional reprogramming in Fusarium graminearum by Fusarium graminearum virus 1-DK21 infection. BMC Genomics. 2012;13:173 pubmed publisher
    ..Taken together, our data aid in the understanding of how FgV1-DK21 regulates the transcriptional reprogramming of F. graminearum. ..
  7. Lian S, Cho W, Jo Y, Kim S, Kim K. Interaction study of rice stripe virus proteins reveals a region of the nucleocapsid protein (NP) required for NP self-interaction and nuclear localization. Virus Res. 2014;183:6-14 pubmed publisher
    ..Overall, our results indicate that the N-terminal region (aa 1-47) of the NP is important for NP self-interaction and that six aa residues (42-47) are essential for both NP self-interaction and nuclear localization. ..
  8. Tran P, Choi H, Choi D, Kim K. Virus-induced gene silencing reveals signal transduction components required for the Pvr9-mediated hypersensitive response in Nicotiana benthamiana. Virology. 2016;495:167-72 pubmed publisher
    ..These results suggest that the Pvr9-mediated HR is possibly related to the SA pathway but not the ET, JA, ROS or NO pathways. ..
  9. Tran P, Widyasari K, Park J, Kim K. Engineering an auto-activated R protein that is in vivo activated by a viral protease. Virology. 2017;510:242-247 pubmed publisher
    ..Our results suggest the potential for transforming malfunctioning and auto-activated R proteins into a new construct targeting potyviral NIa proteases. ..

More Information


  1. Tran P, Widyasari K, Seo J, Kim K. Isolation and validation of a candidate Rsv3 gene from a soybean genotype that confers strain-specific resistance to soybean mosaic virus. Virology. 2018;513:153-159 pubmed publisher
    ..Our results therefore provide additional line of evidence to support that Glyma.14g204700 is likely Rsv3 gene that confers strain-specific resistance to SMV. ..