Research Topics
Genomes and GenesSpecies | Boong Nyun KimSummaryAffiliation: Seoul National University Country: Korea Publications
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Detail Information
Publications
Regional cerebral perfusion abnormalities in attention deficit/hyperactivity disorder. Statistical parametric mapping analysisBoong Nyun Kim
Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, Clinical Research Institute, Seoul National University Hospital, 28 Yungundong, Chongrogu, Seoul, Korea
Eur Arch Psychiatry Clin Neurosci 252:219-25. 2002..A voxel based investigation of cerebral blood flow was conducted to identify brain function differences in the resting state between children with Attention Deficit Hyperactivity Disorder (ADHD) and normal controls...
The relationship between regional cerebral blood flow and response to methylphenidate in children with attention-deficit hyperactivity disorder: comparison between non-responders to methylphenidate and respondersSoo Churl Cho
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, 28 Yungundong, Chongnogu, Seoul, Republic of Korea
J Psychiatr Res 41:459-65. 2007..The current findings suggest that non-responders to MPH may have different patterns of rCBF in brain regions, which have been known as a part of frontal-striatal circuitry and posterior attentional system, respectively...
Clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorderJae Won Kim
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Korea
Alcohol Alcohol 41:407-11. 2006..To examine the clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorder (ADHD)...
Possible association of the alpha-2A-adrenergic receptor gene with response time variability in attention deficit hyperactivity disorderSoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
Am J Med Genet B Neuropsychiatr Genet 147:957-63. 2008..In addition, our results provide evidence for the possible role of these two polymorphisms in ADHD symptom expression, such as increased response time variability...
Regional differences in cerebral perfusion associated with the alpha-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorderBoong Nyun Kim
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul, Republic of Korea
J Psychiatry Neurosci 35:330-6. 2010..Our aim was to examine whether the presence of a risk allele of the ADRA2A MspI polymorphism is associated with differences in regional cerebral blood flow in boys with ADHD...
Regional brain perfusion before and after treatment with methylphenidate may be associated with the G1287A polymorphism of the norepinephrine transporter gene in children with attention-deficit/hyperactivity disorderMin Hyeon Park
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Neurosci Lett 514:159-63. 2012..Further studies should clearly elucidate the relationship between treatment response and functional connectivity in the brain according to this genetic polymorphism...
Possible association of norepinephrine transporter -3081(A/T) polymorphism with methylphenidate response in attention deficit hyperactivity disorderBoong Nyun Kim
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Behav Brain Funct 6:57. 2010..The aims of this study were to examine the association of the SLC6A2 -3081(A/T) and G1287A polymorphisms with MPH response in ADHD...
Full syndrome and subthreshold attention-deficit/hyperactivity disorder in a Korean community sample: comorbidity and temperament findingsSoo Churl Cho
Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Korea
Eur Child Adolesc Psychiatry 18:447-57. 2009..The main objective of this study was to investigate the comorbid disorders and temperamental profiles of full syndrome and subthreshold attention-deficit/hyperactivity disorder (ADHD)...
Effect of ADRA2A and BDNF gene-gene interaction on the continuous performance test phenotypeSoo Churl Cho
Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, Seoul National University College of Medicine, Korea
Psychiatr Genet 21:132-5. 2011..011) of the CPT. Our study provides preliminary evidence for the effect of the BDNF and ADRA2A gene-gene interaction on performance on the CPT in attention-deficit/hyperactivity disorder...
The dopamine transporter gene and the impulsivity phenotype in attention deficit hyperactivity disorder: a case-control association study in a Korean sampleJae Won Kim
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul, Republic of Korea
J Psychiatr Res 40:730-7. 2006..05). The results of this study suggest the possibility of an association between the DAT1 9-repeat allele and the impulsivity phenotype of ADHD...
The effect of OROS methylphenidate on the sleep of children with attention-deficit/hyperactivity disorderHyo Won Kim
Department of Neuropsychiatry, Dongguk University Ilsan Hospital, Korea
Int Clin Psychopharmacol 25:107-15. 2010..001, P=0.036, eta(2)(p)=0.185; F(1)=7.237, P=0.013, eta(2)(p)=0.248). These results suggest that OROS MPH in open-label treatment does not seem to impair sleep and may even improve some aspects of sleep...
Effect of environmental exposure to lead and tobacco smoke on inattentive and hyperactive symptoms and neurocognitive performance in childrenSoo Churl Cho
Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Korea
J Child Psychol Psychiatry 51:1050-7. 2010..The present study assessed the association between blood lead and urinary cotinine levels and inattentive and hyperactive symptoms and neurocognitive performance in children...
No evidence of an association between norepinephrine transporter gene polymorphisms and attention deficit hyperactivity disorder: a family-based and case-control association study in a Korean sampleSoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
Neuropsychobiology 57:131-8. 2008..Our findings do not support SLC6A2 as a major genetic susceptibility factor in ADHD...
Association between the alpha-2C-adrenergic receptor gene and attention deficit hyperactivity disorder in a Korean sampleSoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul, Republic of Korea
Neurosci Lett 446:108-11. 2008..In addition, our results provide evidence that the temperament of Novelty Seeking and ADHD might share molecular genetic characteristics related to the noradrenergic system...
Association between dietary behaviors and attention-deficit/hyperactivity disorder and learning disabilities in school-aged childrenSubin Park
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Psychiatry Res 198:468-76. 2012..These findings are in general the same results in other studies on ADHD children in other countries. However, the cross-sectional study design prevents our ability to assess causal relationships...
Possible effect of norepinephrine transporter polymorphisms on methylphenidate-induced changes in neuropsychological function in attention-deficit hyperactivity disorderSubin Park
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Behav Brain Funct 8:22. 2012..We examined the relationship between polymorphisms in the norepinephrine transporter SLC6A2 gene and attentional performance before and after medication in children with ADHD...
Gender-specific association of the brain-derived neurotrophic factor gene with attention-deficit/hyperactivity disorderSoo Churl Cho
Department of Child and Adolescent Psychiatry, Seoul National University College of Medicine, Seoul, Korea
Psychiatry Investig 7:285-90. 2010..We aimed to explore the relationships between ADHD and BDNF gene polymorphism...
Genome-wide association scan of korean autism spectrum disorders with language delay: a preliminary studySoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Korea
Psychiatry Investig 8:61-6. 2011..Although several genome-wide studies on ASD have suggested a number of candidate genes, few studies have reported the association or linkage of specific endophenotypes to ASDs...
The reliability and validity of Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version- Korean version (K-SADS-PL-K)Young Shin Kim
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Hallym University Sacred Heart Hospital, Anyang, Korea
Yonsei Med J 45:81-9. 2004..Future studies will examine the validity and reliability of the K-SADS-PL-K in larger samples, including adolescents and community samples on a variety of child and adolescent psychiatric disorders...
Are Teacher Ratings and Parent Ratings Differently Associated with Children's Intelligence and Cognitive Performance?Soo Churl Cho
Department of Child and Adolescent Psychiatry, Seoul National University College of Medicine, Seoul, Korea
Psychiatry Investig 8:15-21. 2011..The present study investigated whether teacher ratings and parent ratings of inattentive or hyperactive/impulsive symptoms were differently associated with intelligence or cognitive performance in Korean children...
A 6-month follow-up study of posttraumatic stress and anxiety/depressive symptoms in Korean children after direct or indirect exposure to a single incident of traumaBoong Nyun Kim
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
J Clin Psychiatry 70:1148-54. 2009....
Neurocognitive effects of switching from methylphenidate-IR to OROS-methylphenidate in children with ADHDYeni Kim
Department of Psychiatry, Division of Child and Adolescent Psychiatry, Institute of Human Behavioral Medicine, Seoul National University Hospital, Seoul, Korea
Hum Psychopharmacol 24:95-102. 2009..This study evaluated neurocognitive changes after switching from immediate release forms of methylphenidate (MPH-IR) to osmotic release oral system methylphenidate (OROS-MPH)...
Associations between symptoms of attention deficit hyperactivity disorder, depression, and suicide in Korean female adolescentsSoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Korea
Depress Anxiety 25:E142-6. 2008....
Long-term sustained benefits of clozapine treatment in refractory early onset schizophrenia: a retrospective study in Korean children and adolescentsYeni Kim
Division of Child, Adolescent Psychiatry, Department of Psychiatry and Institute of Human Behavioral Medicine, Seoul National University Hospital, Korea
Hum Psychopharmacol 23:715-22. 2008..We retrospectively examined the therapeutic dosage, clinical response, and side effect profiles of long-term clozapine treatment in Korean children and adolescents with refractory EOS or very early onset schizophrenia (VEOS)...
Biogenetic temperament and character profiles and attention deficit hyperactivity disorder symptoms in Korean adolescents with problematic Internet useSoo Churl Cho
Department of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Chongno Gu, Seoul, Republic of Korea
Cyberpsychol Behav 11:735-7. 2008..The results of this study suggest that temperament/character patterns should be considered in accounts of the etiology of problematic Internet use...
Dopaminergic and noradrenergic gene polymorphisms and response to methylphenidate in korean children with attention-deficit/hyperactivity disorder: is there an interaction?Soon Beom Hong
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
J Child Adolesc Psychopharmacol 22:343-52. 2012....
Temperament and character among Korean children and adolescents with anxiety disordersSoo Churl Cho
Division of Child and Adolescent Psychiatry, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
Eur Child Adolesc Psychiatry 18:60-4. 2009..Children and adolescents with anxiety disorders have different temperaments and character profiles in accordance with diagnostic groups, which implies the specific pathophysiological mechanism of each anxiety disorder...
Retrospective case series of aripiprazole augmentation in pervasive developmental disordersYeni Kim
Division of Child and Adolescent Psychiatry, Department of Psychiatry and Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Korea
Psychiatry Investig 7:220-3. 2010..The results of this study suggest that aripiprazole augmentation may be used safely in maladaptive behaviors of some populations of PDD. However, future studies are required to confirm these preliminary findings...
Computing the shape of brain networks using graph filtration and Gromov-Hausdorff metricHyekyoung Lee
Department of Nuclear Medicine, Seoul National University, College of Medicine, Seoul, Korea
Med Image Comput Comput Assist Interv 14:302-9. 2011....
Copy number variations associated with idiopathic autism identified by whole-genome microarray-based comparative genomic hybridizationSoo Churl Cho
Department of Psychiatry, Seoul National University Hospital, Korea
Psychiatr Genet 19:177-85. 2009..To explore the idiopathic ASD-associated copy number variations (CNVs), we conducted case-control study using whole-genome copy number analysis...
Regional cerebral blood flow in children with attention deficit hyperactivity disorder: comparison before and after methylphenidate treatmentJae Sung Lee
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea
Hum Brain Mapp 24:157-64. 2005..These changes might be associated with improving ADHD to control attention and motor response to irrelevant environmental stimuli after methylphenidate treatment...
Interaction between GSTM1/GSTT1 polymorphism and blood mercury on birth weightBo Eun Lee
Department of Preventive Medicine, School of Medicine, Ewha Woman s University, Seoul, Korea
Environ Health Perspect 118:437-43. 2010..Mercury (Hg) is toxic to both the reproductive and nervous systems. In addition, glutathione S-transferases (GSTs), which conjugate glutathione to a variety of electrophilic compounds, are involved in the detoxification of Hg...
Microsatellite marker in gamma - aminobutyric acid - a receptor beta 3 subunit gene and autism spectrum disorders in Korean triosHanik K Yoo
Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Yonsei Med J 50:304-6. 2009..025), whereas a population-based case-control study, however, showed no association between ASD and GABRB3 microsatellite polymorphism. Our data provide preliminary evidence that GABRB3 gene is associated with ASD in Korea...
