Affiliation: Seoul National University
Yang I, Lee J, Lee J, Hahn D, Chin J, Won D, et al
. Scalalactams A⁻D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge. Molecules. 2018;23: pubmed publisher
..Scalalactams A⁻D (1⁻4) did not show FXR antagonistic activity nor cytotoxicity up to 100 μM. ..
Kim D, Lee J, Londhe A, Kadayat T, Joo J, Hwang H, et al
. Synthesis and evaluation of an orally available "Y"-shaped biaryl peroxisome proliferator-activated receptor δ agonist. Bioorg Med Chem. 2018;26:4382-4389 pubmed publisher
..Our overall results clearly demonstrate that this orally administrable PPARδ agonist 3a is a viable drug candidate for the treatment of various PPARδ-related disorders. ..
Yang I, Choi H, Nam S, Kang H. A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp. Arch Pharm Res. 2015;38:1970-4 pubmed publisher
..The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25Â Î¼gÂ ml(-1), respectively. ..
Wang W, Kim H, Patil R, Giri A, Won D, Hahn D, et al
. Cadiolides J-M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinboja. Bioorg Med Chem Lett. 2017;27:574-577 pubmed publisher
Yim C, Le T, Lee T, Yang I, Choi H, Lee J, et al
. Saccharomonopyrones A-C, New ?-Pyrones from a Marine Sediment-Derived Bacterium Saccharomonospora sp. CNQ-490. Mar Drugs. 2017;15: pubmed publisher
..Saccharomonopyrone A exhibited weak antioxidant activity using a cation radical scavenging activity assay with an IC50 value of 140 ?M. ..