G H Kang


Affiliation: Seoul National University
Country: Korea


  1. Kim Y, Lee K, Jeong S, Wen X, Cho N, Kang G. DLEC1 methylation is associated with a better clinical outcome in patients with intrahepatic cholangiocarcinoma of the small duct subtype. Virchows Arch. 2019;: pubmed publisher
    ..Our findings suggest that DLEC1 methylation can be utilized to identify a subset with a better prognosis in intrahepatic cholangiocarcinomas of the small duct type. ..
  2. Kim K, Lee K, Cho H, Kim Y, Yang H, Kim W, et al. Prognostic implications of tumor-infiltrating FoxP3+ regulatory T cells and CD8+ cytotoxic T cells in microsatellite-unstable gastric cancers. Hum Pathol. 2014;45:285-93 pubmed publisher
  3. Kim Y, Wen X, Jeong S, Cho N, Kim W, Kang G. Combinatory low methylation statuses of SAT-α and L1 are associated with shortened survival time in patients with advanced gastric cancer. Gastric Cancer. 2018;: pubmed publisher
    ..SAT-α methylation status can be used to further divide gastric cancers with L1 hypomethylation into subsets of gastric cancers with better and worse prognosis. ..
  4. Jang B, Kim H, Chang W, Bae J, Kim W, Kang G. Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression. Am J Pathol. 2018;188:2236-2250 pubmed publisher
    ..Likewise, knockdown of LGR5 expression resulted in a decline in the colony-forming and migration capacities in LoVo cells. Taken together, our data suggest a suppressive role of LGR5 in CRC progression. ..
  5. Kang J, Song S, Yun J, Jeon M, Cha Y, Lee S, et al. Identification of long-range epigenetic silencing on chromosome 15q25 and its clinical implication in gastric cancer. Am J Pathol. 2015;185:666-78 pubmed publisher
    ..Patients with LRES showed lower recurrence and better prognosis, indicating that stratifying patients according to underlying molecular features, such as LRES regions, may better predict recurrence and survival. ..
  6. Song Y, Kim Y, Cho N, Yang H, Kim W, Kang G. Methylation status of long interspersed element-1 in advanced gastric cancer and its prognostic implication. Gastric Cancer. 2016;19:98-106 pubmed publisher
  7. Kim J, Kim K, Rhee Y, Bae J, Cho N, Lee H, et al. Gastric-type expression signature in serrated pathway-associated colorectal tumors. Hum Pathol. 2015;46:643-56 pubmed publisher
    ..In conclusion, the early gain of gastric differentiation and late loss of intestinal differentiation are immunophenotypic features in the serrated pathway to colorectal carcinoma. ..
  8. Bae J, Rhee Y, Kim K, Wen X, Song Y, Cho N, et al. Are clinicopathological features of colorectal cancers with methylation in half of CpG island methylator phenotype panel markers different from those of CpG island methylator phenotype-high colorectal cancers?. Hum Pathol. 2016;47:85-94 pubmed publisher
  9. Kang G. Four molecular subtypes of colorectal cancer and their precursor lesions. Arch Pathol Lab Med. 2011;135:698-703 pubmed publisher
    ..In particular, the clinicopathologic features of MSI+ CRCs differ depending on the CIMP status. Further understanding of the heterogeneity in CRC molecular pathways may help to explain the diverse morphologic features of CRCs. ..

More Information


  1. Bae J, Lee J, Cho J, Lim S, Kang G. Synchronous mucosal Schwann-cell hamartomas in a young adult suggestive of mucosal Schwann-cell harmatomatosis: a case report. BMC Gastroenterol. 2015;15:128 pubmed publisher
    ..To the best of our knowledge, this is the first report of a case of multiple mucosal Schwann-cell hamartomas. ..
  2. Lee D, Han S, Cha Y, Lee K, Kim T, Oh D, et al. Prognostic influence of body mass index and body weight gain during adjuvant FOLFOX chemotherapy in Korean colorectal cancer patients. BMC Cancer. 2015;15:690 pubmed publisher
    ..0 kg/m(2)). In Korean colorectal cancer patients treated with adjuvant FOLFOX chemotherapy, body weight gain during the treatment period has a negative prognostic influence in overweight and obese patients. ..
  3. Jang B, Kim H, Chang W, Bae J, Oh H, Wen X, et al. Prognostic significance of stromal GREM1 expression in colorectal cancer. Hum Pathol. 2017;62:56-65 pubmed publisher
  4. Park H, Kim J, Cho N, Lee H, Kang G. Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma. Virchows Arch. 2017;471:329-336 pubmed publisher
    ..In conclusion, high amounts of intratumoral Fn are correlated with increased macrophage infiltration and CDKN2A promoter methylation in MSI-H CRCs. ..
  5. Kim K, Lee T, Kim J, Cho N, Kim W, Kang G. Deletion in HSP110 T17: correlation with wild-type HSP110 expression and prognostic significance in microsatellite-unstable advanced gastric cancers. Hum Pathol. 2017;67:109-118 pubmed publisher
    ..Large HSP110 T17 was not a prognostic indicator in MSI-H GCs. ..
  6. Jeong S, Lee K, Wen X, Kim Y, Cho N, Jang J, et al. Tumoral LINE-1 hypomethylation is associated with poor survival of patients with intrahepatic cholangiocarcinoma. BMC Cancer. 2017;17:588 pubmed publisher
    ..Our findings suggest that tumoral LINE-1 hypomethylation could be a molecular biomarker heralding poor prognosis of patients with intrahepatic cholangiocarcinoma. Our findings need to be validated in further study. ..