Eun Yi Moon


Affiliation: Sejong University
Country: Korea


  1. Kim D, Moon E, Yi J, Lee H, Park S, Ryu Y, et al. Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory. Neuroscience. 2015;310:51-62 pubmed publisher
    ..Taken together, these data demonstrate that Ac-SDKP functions as a regulator of neural proliferation and indicate that Ac-SDKP may be a therapeutic candidate for diseases characterized by neuronal loss. ..
  2. Lee J, Park S, Kim S, Um S, Moon E. Curcumin hampers the antitumor effect of vinblastine via the inhibition of microtubule dynamics and mitochondrial membrane potential in HeLa cervical cancer cells. Phytomedicine. 2016;23:705-13 pubmed publisher
    ..It also suggests that microtubule dynamics could be necessary for the optimal antitumor activity of vinblastine. Our results suggest that patients treated with vinblastine should not consume curcumin. ..
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    Moon E, Pyo S. Lipopolysaccharide stimulates Epac1-mediated Rap1/NF-kappaB pathway in Raw 264.7 murine macrophages. Immunol Lett. 2007;110:121-5 pubmed
    ..It suggests that Epac1-mediated Rap1/NF-kappaB pathway could be helpful for interpretation on various cAMP-mediated physiological responses and it could be used as a target to control their pathological abnormalities. ..
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    Moon E, Park H. B cell activating factor (BAFF) gene promoter activity depends upon co-activator, p300. Immunobiology. 2007;212:637-45 pubmed
    ..Data suggest that mBAFF expression could be regulated by promoter activation through NF-kappaB activation, which might be dependent on the cooperation with co-activator, p300. ..
  5. Moon E, Kang J, Han S, Yang K, Pyo S, Lee M, et al. Differential role of peroxiredoxin II (PrxII) on the expression of toll-like receptor 4 (TLR4) and B-cell activating factor (BAFF) in ovalbumin (OVA)-induced mouse asthma. Int Immunopharmacol. 2008;8:935-44 pubmed publisher
    ..Collectively, results show that PrxII may have benefits in asthma through reducing ROS. It suggests that BAFF and TLR4 expressions are differentially regulated by PrxII and TLR4 protein level may not be crucial in OVA-induced asthma. ..
  6. Moon E, Im Y, Ryu Y, Kang J. Actin-sequestering protein, thymosin beta-4, is a novel hypoxia responsive regulator. Clin Exp Metastasis. 2010;27:601-9 pubmed publisher
    ..It suggests that TB4 could be a hypoxia responsive regulator to control tumor cell migration in angiogenesis and tumor metastasis...
  7. Moon E, Lee J, Lee J, Song J, Pyo S. ROS/Epac1-mediated Rap1/NF-kappaB activation is required for the expression of BAFF in Raw264.7 murine macrophages. Cell Signal. 2011;23:1479-88 pubmed publisher
    ..It suggests for the first time that ROS/Epac1-mediated Rap1/NF-?B pathway could be required for BAFF expression. ..
  8. Moon E, Lee Y, Choi W, Lee M. Toll-like receptor 4-mediated cAMP production up-regulates B-cell activating factor expression in Raw264.7 macrophages. Exp Cell Res. 2011;317:2447-55 pubmed publisher
    ..With these data, it suggests that the activation of PKA and cAMP/Epac1/Rap1 pathways could be required for basal mBAFF expression, as well as being up-regulated in the TLR4-induced mBAFF expression. ..
  9. Ryu Y, Lee M, Lee J, Lee J, Jang S, Kang J, et al. γ-Irradiated cancer cells promote tumor growth by activation of Toll-like receptor 1-mediated inducible nitric oxide synthase in macrophages. J Leukoc Biol. 2015;97:711-21 pubmed publisher
    ..Our data suggest that iNOS in macrophages could be a useful target to regulate postradiotherapeutic responses in hosts and subsequently limit tumor regrowth. ..

More Information


  1. Chau G, Im D, Kang T, Bae J, Kim W, Pyo S, et al. mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress. J Cell Biol. 2017;216:2091-2105 pubmed publisher
    ..Thus, our results suggest that a nutrient-sensitive mTOR-regulated transcriptional network could be a novel target to improve β cell survival and glucose homeostasis in diabetes. ..
  2. Lee J, Park S, Han H, Gye M, Moon E. Di-(2-ethylhexyl) phthalate enhances melanoma tumor growth via differential effect on M1-and M2-polarized macrophages in mouse model. Environ Pollut. 2018;233:833-843 pubmed publisher
    ..This suggests that individuals at high risk for tumor incidence should avoid long-term exposure to various kind of phthalate including DEHP. ..