Soo Jeong Lim

Summary

Affiliation: Sejong University
Country: Korea

Publications

  1. ncbi request reprint 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole acts in a reactive oxygen species-dependent manner to suppress human lung cancer growth
    Eunmyong Lee
    Research Institute, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang, Gyeonggi, Korea
    J Cancer Res Clin Oncol 132:223-33. 2006
  2. doi request reprint Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Mol Med Rep 2:497-502. 2009
  3. ncbi request reprint p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Oncol Rep 16:1131-5. 2006
  4. ncbi request reprint Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea
    Apoptosis 12:423-31. 2007
  5. pmc Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Exp Mol Med 41:737-45. 2009
  6. doi request reprint Dual function of tributyrin emulsion: solubilization and enhancement of anticancer effect of celecoxib
    Sung Nam Kang
    Department of Bioscience and Biotechnology, Sejong University, 98 Kunja dong, Kwangjin gu, Seoul 143 747, Republic of Korea
    Int J Pharm 428:76-81. 2012
  7. ncbi request reprint Alpha-tocopheryl succinate, in contrast to alpha-tocopherol and alpha-tocopheryl acetate, inhibits prostaglandin E2 production in human lung epithelial cells
    Eunmyong Lee
    Department of Bioscience and Biotechnology, Sejong University Seoul, Korea
    Carcinogenesis 27:2308-15. 2006
  8. doi request reprint Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Republic of Korea
    Oncol Rep 27:2023-30. 2012
  9. doi request reprint Cyclooxygenase-2/prostaglandin E₂ inducing effects of α-tocopheryl polyethylene glycol succinate in lung epithelial cells
    Eun Hye Lee
    Department of Bioscience and Biotechnology, Sejong University, Seoul, 143 747, Korea
    Arch Pharm Res 35:1639-44. 2012
  10. ncbi request reprint Comparison of three tocopherol analogs as an inhibitor of production of proinflammatory mediators in macrophages
    Sukyoung Kim
    Department of Bioscience and Biotechnology, College of Life Sciences, Sejong University, Korea
    J Pharmacol Sci 118:237-44. 2012

Collaborators

  • Hyo Kyung Han
  • Joon Seok Lim
  • Sang Yoon Kim
  • Kyung Hee Kim
  • Kyung Hee Chun
  • Sunho Lee
  • Chang Hun Lee
  • Hwangseo Park
  • Eun Hee Kim
  • Jin Sung Choi
  • F J Esteva
  • Eunmyong Lee
  • Eun Hye Lee
  • Soon Seok Hong
  • Mi Kyung Lee
  • Sung Nam Kang
  • Dong Il Kang
  • Moon Kyung Choi
  • Hee Jeong Youk
  • Young Hwa Kang
  • Honsoul Kim
  • Chong Kook Kim
  • Inn Oc Han
  • Jin Ki Kim
  • Woo Jin Hyung
  • Soonjae Kweon
  • Min Jung Kim
  • Young Ju Lee
  • Ja Lok Ku
  • Young Kyoung Shin
  • Yong Geun Park
  • Seung Rim Hwang
  • So Young Hwang
  • Jong Oh Kim
  • Jaemoon Yang
  • Yoo Min Kim
  • Myo Sook Hong
  • Ana M Tari
  • Byung Je Sung
  • Ji Yong Yoon
  • Junho Chung
  • Jung Tae Lee
  • Jinsuk Suh
  • Ho Joon Lee
  • Hye Sun Gwak
  • He Kyung Kang
  • Byung Chul Yoo
  • Cheol Hyeon Kim
  • Eunkyung Jeon
  • Jae Gahb Park
  • Byong Chul Yoo
  • Hee Jin Chang
  • Sung Hye Hong
  • Mi Sun Jung
  • Hyun Jang Lee
  • Jun Ho Chung
  • Kwan Ho Cho
  • Jeong Sook Park
  • Joo Young Kim
  • Tae Hyun Kim
  • Jae Seob Jung
  • Mien Chie Hung
  • Yu Kyoung Oh
  • Gabriel Lopez-Berestein

Detail Information

Publications44

  1. ncbi request reprint 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole acts in a reactive oxygen species-dependent manner to suppress human lung cancer growth
    Eunmyong Lee
    Research Institute, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang, Gyeonggi, Korea
    J Cancer Res Clin Oncol 132:223-33. 2006
    ....
  2. doi request reprint Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Mol Med Rep 2:497-502. 2009
    ..Butyrate may act as a preventive and therapeutic agent in the progression of colorectal cancer through the regulation of heregulin-stimulated mitogenic signaling...
  3. ncbi request reprint p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Oncol Rep 16:1131-5. 2006
    ..Such combinations may provide a more effective and less toxic strategy for the prevention or treatment of colon cancer...
  4. ncbi request reprint Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea
    Apoptosis 12:423-31. 2007
    ..Apoptotic synergy induced by exisulind plus TOS seems likely to be mediated through a mechanism involving activation of caspases and JNK...
  5. pmc Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Exp Mol Med 41:737-45. 2009
    ....
  6. doi request reprint Dual function of tributyrin emulsion: solubilization and enhancement of anticancer effect of celecoxib
    Sung Nam Kang
    Department of Bioscience and Biotechnology, Sejong University, 98 Kunja dong, Kwangjin gu, Seoul 143 747, Republic of Korea
    Int J Pharm 428:76-81. 2012
    ..These data suggest that the anticancer activity of celecoxib was enhanced by loading in tributyrin emulsions, probably due to the solubilization capacity and anticancer activity of tributyrin emulsion...
  7. ncbi request reprint Alpha-tocopheryl succinate, in contrast to alpha-tocopherol and alpha-tocopheryl acetate, inhibits prostaglandin E2 production in human lung epithelial cells
    Eunmyong Lee
    Department of Bioscience and Biotechnology, Sejong University Seoul, Korea
    Carcinogenesis 27:2308-15. 2006
    ..Administration of alphaTOS may block inflammatory responses mediated by PGE2, thereby inhibiting the initiation and progression of lung cancer...
  8. doi request reprint Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Republic of Korea
    Oncol Rep 27:2023-30. 2012
    ..Our findings collectively support the utility of a combination of sulindac sulfide and DHA in the effective prevention and treatment of colon cancer...
  9. doi request reprint Cyclooxygenase-2/prostaglandin E₂ inducing effects of α-tocopheryl polyethylene glycol succinate in lung epithelial cells
    Eun Hye Lee
    Department of Bioscience and Biotechnology, Sejong University, Seoul, 143 747, Korea
    Arch Pharm Res 35:1639-44. 2012
    ..Since the use of αTPGS as a surfactant component of dispersive drug delivery systems is frequently considered, caution should be taken when the drugs involved in COX signaling are loaded in αTPGS-included delivery systems...
  10. ncbi request reprint Comparison of three tocopherol analogs as an inhibitor of production of proinflammatory mediators in macrophages
    Sukyoung Kim
    Department of Bioscience and Biotechnology, College of Life Sciences, Sejong University, Korea
    J Pharmacol Sci 118:237-44. 2012
    ..The inclusion of αTOS in vitamin supplements may further enhance the effectiveness of strategies for preventing diseases associated with inflammation...
  11. ncbi request reprint Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells
    Min Jung Kim
    Department of Bioscience and Biotechnology, Sejong University, 98 Kunja dong, Kwangjin gu, Seoul, Korea
    Anticancer Res 30:3611-9. 2010
    ..Taken together, sulforaphane analogues with oxidised sulphur were the most efficient apoptosis inducers, likely due to high-level ROS induction...
  12. doi request reprint Computed tomography-guided screening of surfactant effect on blood circulation time of emulsions: application to the design of an emulsion formulation for paclitaxel
    Eun Hye Lee
    Department of Bioscience and Bioengineering, Sejong University, Seoul, Republic of Korea
    Pharm Res 31:2022-34. 2014
    ....
  13. doi request reprint Nanoscale iodized oil emulsion: a useful tracer for pretreatment sentinel node detection using CT lymphography in a normal canine gastric model
    Joon Seok Lim
    Department of Radiology, Yonsei University College of Medicine, Seoul, Korea
    Surg Endosc 26:2267-74. 2012
    ..The aim of this study was to determine whether computed tomographic (CT) lymphography using nanoscale iodized oil emulsion via endoscopic submucosal injection can visualize LNs...
  14. doi request reprint Preparation and in vitro evaluation of anti-VCAM-1-Fab'-conjugated liposomes for the targeted delivery of the poorly water-soluble drug celecoxib
    Dong Il Kang
    Department of Bioscience and Biotechnology, Sejong University, 98 Gunja Dong, Gwangjin gu, Seoul 143 747, Korea
    J Microencapsul 28:220-7. 2011
    ..Therefore, Fab'-conjugated liposomes served as a drug delivery system with dual functions: targeted delivery and solubilizing capacity...
  15. doi request reprint Fluorescent iodized emulsion for pre- and intraoperative sentinel lymph node imaging: validation in a preclinical model
    Honsoul Kim
    From the Department of Radiology H K, J Y, J S L, Research Institute of Radiological Science H K, J S L, Gastric Cancer Clinic H K, S K L, J S L, W J H, and Department of Internal Medicine S K L, Department of Pathology S H K, YUHS KRIBB Medical Convergence Research Institute J Y, Department of Surgery W J H, and Robot and MIS Center W J H, Severance Hospital, Yonsei University College of Medicine, 50 1 Yonsei ro, Seodaemun gu, Seoul 120 752, Republic of Korea Department of Surgery, Bundang CHA Hospital, CHA University College of Medicine, Seongnam, Republic of Korea Y M K Department of Bioscience and Bioengineering, Sejong University, Seoul, Republic of Korea E H L, S J L
    Radiology 275:196-204. 2015
    ..To validate the usefulness of a newly developed tracer for preoperative gastric sentinel lymph node (LN) (SLN) mapping and intraoperative navigation after a single preoperative submucosal injection in rat and beagle models...
  16. ncbi request reprint The association of increased lung resistance protein expression with acquired etoposide resistance in human H460 lung cancer cell lines
    Eunmyong Lee
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea
    Arch Pharm Res 29:1018-23. 2006
    ..We found that the acquired resistance paralleled an increased expression of LRP in H460 cells. Taken together, our data suggest the implicative role of LRP in mediating MDR in lung cancer...
  17. ncbi request reprint Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells
    Eunmyong Lee
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143 747, Korea
    Exp Mol Med 38:325-31. 2006
    ..These results suggest that p21CIP1 blocks the SC-560-induced apoptotic response of HCT116 cells. SC-560 combined with other therapy that can block p21 CIP1 expression or function may contribute to the effective treatment of colon cancer...
  18. doi request reprint Preparation and evaluation of tributyrin emulsion as a potent anti-cancer agent against melanoma
    Sung Nam Kang
    Department of Bioscience and Biotechnology, Sejong University, 98 Kunja dong, Kwangjin gu, Seoul, Korea 143 747
    Drug Deliv 18:143-9. 2011
    ..Taken together, our data suggests that tributyrin emulsion may be developed as a potent anti-cancer agent against melanoma...
  19. doi request reprint Aminoclay as a highly effective cationic vehicle for enhancing adenovirus-mediated gene transfer through nanobiohybrid complex formation
    Soo Yeon Kim
    Department of Integrative Bioscience and Bioengineering, Sejong University, Seoul, 98 Kunja dong, Kwangjin gu, Seoul 05006, Republic of Korea
    Acta Biomater . 2016
    ..Aminoclay-Ad nanobiohybrids may serve as a next-generation efficient, versatile and biocompatible gene-delivery carrier...
  20. pmc Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation
    Soon Seok Hong
    Department of Bioscience and Bioengineering, Sejong University, Seoul
    Int J Nanomedicine 11:4465-4477. 2016
    ..Taken together, triglyceride incorporation provided an injectable PTX formulation by functioning as a formulation stabilizer of PEGylated/saturated PC-based liposomes...
  21. doi request reprint Enhancement of indocyanine green stability and cellular uptake by incorporating cationic lipid into indocyanine green-loaded nanoemulsions
    Eun Hye Lee
    Department of Bioscience and Bioengineering, Institute of Bioscience, Sejong University, Seoul, Republic of Korea
    Colloids Surf B Biointerfaces 136:305-13. 2015
    ..Our findings indicate that SA-incorporated nanoemulsions are promising ICG carriers for combined diagnosis and treatment of lymph node metastases. ..
  22. doi request reprint Liposome composition is important for retention of liposomal rhodamine in P-glycoprotein-overexpressing cancer cells
    Dong Il Kang
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea
    Drug Deliv 16:261-7. 2009
    ..Taken together, these findings suggest that Pgp-mediated MDR in cancer cells may be more effectively modulated by optimizing the composition of liposomes for loading Pgp-substrate anti-cancer drugs...
  23. doi request reprint Effects of triglycerides on the hydrophobic drug loading capacity of saturated phosphatidylcholine-based liposomes
    Soon Seok Hong
    Department of Bioscience and Bioengineering, Institute of Bioscience, 98 Kunja dong, Kwangjin gu, Sejong University, Seoul, Republic of Korea
    Int J Pharm 483:142-50. 2015
    ....
  24. doi request reprint Effect of sodium carboxymethylcellulose and fucidic acid on the gel characterization of polyvinylalcohol-based wound dressing
    Soo Jeong Lim
    Department of Bioscience and Biotechnology of Life Sciences and Biotechnology, Sejong University, Seoul, Korea
    Arch Pharm Res 33:1073-81. 2010
    ..5% PVA, 1.125% Na-CMC and 0.2% drug might give an adequate level of moisture and build up the exudates on the wound area. Thus, this sodium fucidate-loaded hydrogel could be a potential candidate for wound dressing with excellent forming...
  25. ncbi request reprint Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment
    Soo Jeong Lim
    Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Nucl Med 48:398-404. 2007
    ..We investigated the effect of retinoic acid on adenovirus-mediated expression of the human NIS gene in the MCF-7 breast cancer cell line...
  26. ncbi request reprint Induction of G2 arrest and apoptosis of raji cells by continuous low-dose beta irradiation with 188Re-perrhenate
    Soo Jeong Lim
    Laboratory of Cyclotron Application, Korea Institute of Radiological and Medical Science, Seoul, Korea
    Cancer Biother Radiopharm 21:314-20. 2006
    ..In summary, our results showed that continuous irradiation with low-dose beta-rays induced G(2) arrest and progressive apoptosis, which may be characteristic mechanisms of radionuclide therapy...
  27. doi request reprint Formulation and in vitro and in vivo evaluation of a cationic emulsion as a vehicle for improving adenoviral gene transfer
    Soo Yeon Kim
    Department of Bioscience and Bioengineering, Sejong University, 98 Kunja dong, Kwangjin gu, Seoul 143 747, Republic of Korea
    Int J Pharm 475:49-59. 2014
    ..Additionally, the observation of increased transgene expression in lung together with reduced expression in liver demonstrates that the adenovirus-emulsion complex may act as a lung-targeting adenoviral gene delivery system. ..
  28. doi request reprint Increased chemoresistance to paclitaxel in the MCF10AT series of human breast epithelial cancer cells
    Soo Jeong Lim
    Department of Bioscience and Biotechnology, Sejong University, Seoul, Republic of Korea
    Oncol Rep 33:2023-30. 2015
    ..The decreased responsiveness to paclitaxel observed in 10CA1a tumor cells was likely due, in part, to activation of the Akt signaling pathway and a high expression of wild-type p53 with lack of p21Waf1/Cip1. ..
  29. doi request reprint Liposomes coloaded with iopamidol/lipiodol as a RES-targeted contrast agent for computed tomography imaging
    Soonjae Kweon
    Department of Bioscience and Bioengineering, Sejong University, Seoul, Republic of Korea
    Pharm Res 27:1408-15. 2010
    ..The present study was performed to investigate a possibility to overcome the limitations of entrapped iodine in liposomes by preparing liposomes co-loaded with iopamidol, a water-soluble iodinated compound, and lipiodol, an iodized oil...
  30. doi request reprint A structure-based virtual screening approach toward the discovery of histone deacetylase inhibitors: identification of promising zinc-chelating groups
    Hwangseo Park
    Department of Bioscience and Biotechnology, Sejong University, 98 Kunja dong, Kwangjin ku, Seoul 143 747, Korea
    ChemMedChem 5:591-7. 2010
    ..Interactions with the HDAC1 active site residues responsible for stabilizing these new inhibitors are addressed in detail...
  31. ncbi request reprint LY294002 inhibits interferon-gamma-stimulated inducible nitric oxide synthase expression in BV2 microglial cells
    So Young Hwang
    Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea
    Biochem Biophys Res Commun 318:691-7. 2004
    ....
  32. ncbi request reprint Enhanced anticancer efficacy of alpha-tocopheryl succinate by conjugation with polyethylene glycol
    Hee Jeong Youk
    Research Institute, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang, Gyeonggi, 411 764, South Korea
    J Control Release 107:43-52. 2005
    ....
  33. ncbi request reprint Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance
    Young Kyoung Shin
    Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, 411 764, Korea
    Cancer Res 65:3162-70. 2005
    ..Our findings show that ATP synthase down-regulation may not only be a bioenergetic signature of colorectal carcinomas but may also lead to cellular events responsible for 5-FU resistance...
  34. ncbi request reprint Folate-tethered emulsion for the target delivery of retinoids to cancer cells
    Sung Hoon Kim
    Laboratory of Excellency for Drug and Gene Delivery, Seoul National University, Seoul, Republic of Korea
    Eur J Pharm Biopharm 68:618-25. 2008
    ..Folate-tethered lipid emulsion showed effective and selective delivery to the folate receptor-abundant carcinomas, suggesting a potential for targeted delivery of anticancer agents...
  35. ncbi request reprint Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells
    Young Hwa Kang
    Research Institute, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang, Gyeonggi 411 769, South Korea
    Cancer Lett 217:181-90. 2005
    ..TOS may be a promising adjuvant for enhancing the therapeutic efficacy of VP-16 in patients with MRP1-expressing glioblastomas...
  36. ncbi request reprint N-(4-hydroxyphenyl)-retinamide selectively increases All-TRANS retinoic acid inhibitory effects in HER2/NEU-overexpressing breast cancer cells
    Soo Jeong Lim
    Department of Bioimmunotherapy, Section of Immunobiology and Drug Carriers, University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    Tumour Biol 23:279-86. 2002
    ..Combining 4HPR with ATRA may lead to a novel, selective therapeutic or chemopreventive strategy against HER2/NEU-overexpressing breast tumors...
  37. ncbi request reprint Altered chemical and biological activities of all-trans retinoic acid incorporated in solid lipid nanoparticle powders
    Soo Jeong Lim
    Research Institute, National Cancer Center, Goyang, Gyeonggi, Korea
    J Control Release 100:53-61. 2004
    ..SLN powder formulation of ATRA may have a potential in enhancing the efficacy of ATRA in cancer chemoprevention and therapeutics...
  38. ncbi request reprint pH-sensitive, serum-stable and long-circulating liposomes as a new drug delivery system
    Myo Sook Hong
    College of Pharmacy, Seoul National University, Kwanak gu, South Korea
    J Pharm Pharmacol 54:51-8. 2002
    ..The complete destabilization of the liposomes at tumour tissues suggests that the liposomes might be useful for the targeted delivery of drugs such as anticancer agents...
  39. ncbi request reprint Recent progress in drug delivery systems for anticancer agents
    Chong Kook Kim
    National Research Lab for Drug and Gene Delivery, College of Pharmacy, Seoul National University, Kwanak gu, Korea
    Arch Pharm Res 25:229-39. 2002
    ..New technologies and multidisciplinary expertise to develop advanced drug delivery systems, applicable to a wide range of anticancer agents, may eventually lead to an effective cancer therapy in the future...
  40. ncbi request reprint Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells
    Ana M Tari
    Department of Bioimmunotherapy, Section of Immunobiology and Drug Carriers, The University of Texas M D Anderson Cancer Center, Houston, Texas, TX 77030, USA
    Oncogene 21:5224-32. 2002
    ..ATRA sensitivity was also correlated with RARalpha protein levels since higher RARalpha protein levels were observed in cells in which the Her2/neu pathway was inhibited...
  41. ncbi request reprint Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid
    Soo Jeong Lim
    National Research Lab for Drug and Gene Delivery, College of Pharmacy, Researche Institute of Pharmaceutical Sciences, Seoul National University, San 56 1, Shinlim Dong, Kwanak gu, Seoul 151 742, South Korea
    Int J Pharm 243:135-46. 2002
    ..Taken together, SLN formulation of ATRA with similar characteristics to those of parenteral emulsions could be obtained even after freeze-drying...
  42. ncbi request reprint Cyclosporin A enhances the apoptotic effects of N-(4-hydroxyphenyl)retinamide in breast cancer cells
    Soo Jeong Lim
    Section of Immunobiology and Drug Carriers, Department of Bioimmunotherapy, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Cancer 101:243-7. 2002
    ..Thus, the 4HPR and cyclosporin A combination may potentially be a novel therapeutic modality against breast tumors...
  43. ncbi request reprint Phospholipid-based microemulsion formulation of all-trans-retinoic acid for parenteral administration
    Seung Rim Hwang
    National Research Laboratory for Drug and Gene Delivery, College of Pharmacy, Seoul National University, San 56 1, Shillim Dong, Kwanak gu, Seoul 151 742, South Korea
    Int J Pharm 276:175-83. 2004
    ..Our study herein demonstrates that phospholipid-based microemulsion may provide an alternative parenteral formulation of ATRA...
  44. ncbi request reprint Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate
    Young Hwa Kang
    Research Institute, National Cancer Center, Goyang, Gyeonggi, Korea
    Int J Cancer 112:385-92. 2004
    ..Taken together, our findings suggest an important role of ROS generation in TOS-induced, caspase-independent apoptosis of cancer cells...