Byung Chul Yoo

Summary

Affiliation: Samsung Medical Center
Country: Korea

Publications

  1. ncbi Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea
    Byung Chul Yoo
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    J Hepatol 38:98-103. 2003
  2. pmc Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy
    Sun Young Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 20:433-7. 2005
  3. ncbi [Relationship between core gene mutations of hepatitis B virus and response to alpha interferon therapy in chronic hepatitis B]
    Byung Chul Yoo
    Department of Gastroenterology, College of Medicine, Chung Ang University, Seoul, Korea
    Taehan Kan Hakhoe Chi 8:381-8. 2002
  4. doi Efficacy of peg-interferon-α-2a plus ribavirin for patients aged 60 years and older with chronic hepatitis C in Korea
    Dong Hyun Sinn
    Department of Medicine, Armed Forces Capital Hospital, Seongnam, South Korea
    J Gastroenterol Hepatol 26:469-76. 2011
  5. ncbi Risk factors for relapse in chronic hepatitis C patients who have achieved end of treatment response
    Su Rin Shin
    Department of Medicine, Kangnam Sacred Hospital, Hallym University, Seoul, Korea
    J Gastroenterol Hepatol 25:957-63. 2010
  6. doi Upper normal threshold of serum alanine aminotransferase in identifying individuals at risk for chronic liver disease
    Ha Na Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Liver Int 32:937-44. 2012
  7. doi Risk factors and a predictive model for acute hepatic failure after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma
    Yang Won Min
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Liver Int 33:197-202. 2013
  8. doi Early three-dimensional conformal radiotherapy for patients with unresectable hepatocellular carcinoma after incomplete transcatheter arterial chemoembolization: a prospective evaluation of efficacy and toxicity
    Dongryul Oh
    Departments of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Am J Clin Oncol 33:370-5. 2010
  9. doi Ribavirin dose and treatment outcome of Korean patients with genotype 1 chronic hepatitis C
    Dong Hyun Sinn
    Department of Medicine, Samsung Medical Center, Seoul, South Korea
    Hepatogastroenterology 59:1-6. 2012
  10. ncbi Milan criteria are useful predictors for favorable outcomes in hepatocellular carcinoma patients undergoing liver transplantation after transarterial chemoembolization
    Do Young Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, 135 710, Seoul, South Korea
    World J Gastroenterol 12:6992-7. 2006

Collaborators

Detail Information

Publications100

  1. ncbi Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea
    Byung Chul Yoo
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    J Hepatol 38:98-103. 2003
    ..The aims of this study were to determine the frequency of precore/core promoter mutations and hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (e-CHB) in Korea...
  2. pmc Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy
    Sun Young Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 20:433-7. 2005
    ..Our result suggests that false HBsAg negativity can be induced by combination of overlapping gene mutations during the lamivudine therapy...
  3. ncbi [Relationship between core gene mutations of hepatitis B virus and response to alpha interferon therapy in chronic hepatitis B]
    Byung Chul Yoo
    Department of Gastroenterology, College of Medicine, Chung Ang University, Seoul, Korea
    Taehan Kan Hakhoe Chi 8:381-8. 2002
    ....
  4. doi Efficacy of peg-interferon-α-2a plus ribavirin for patients aged 60 years and older with chronic hepatitis C in Korea
    Dong Hyun Sinn
    Department of Medicine, Armed Forces Capital Hospital, Seongnam, South Korea
    J Gastroenterol Hepatol 26:469-76. 2011
    ..In the present study, we evaluated the safety and efficacy of combination therapy with pegylated interferon and ribavirin for treating chronic hepatitis C (CHC) patients aged 60 years and older...
  5. ncbi Risk factors for relapse in chronic hepatitis C patients who have achieved end of treatment response
    Su Rin Shin
    Department of Medicine, Kangnam Sacred Hospital, Hallym University, Seoul, Korea
    J Gastroenterol Hepatol 25:957-63. 2010
    ..Prolonged therapy can be effective for helping such high-risk patients to avoid relapse. We aimed to identify factors predictive of virologic relapse in chronic hepatitis C patients who have achieved end of treatment response...
  6. doi Upper normal threshold of serum alanine aminotransferase in identifying individuals at risk for chronic liver disease
    Ha Na Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Liver Int 32:937-44. 2012
    ..Serum alanine aminotransferase (ALT) is an easily available, low-cost screening tool for detecting silent chronic liver disease. Recent studies have suggested that the currently accepted healthy ALT thresholds be lowered...
  7. doi Risk factors and a predictive model for acute hepatic failure after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma
    Yang Won Min
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Liver Int 33:197-202. 2013
    ..Acute hepatic failure (AHF) is one of the most serious complications of transcatheter arterial chemoembolization (TACE). The aims of this study were to investigate risk factors of AHF after TACE and to establish a predictive model for AHF...
  8. doi Early three-dimensional conformal radiotherapy for patients with unresectable hepatocellular carcinoma after incomplete transcatheter arterial chemoembolization: a prospective evaluation of efficacy and toxicity
    Dongryul Oh
    Departments of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Am J Clin Oncol 33:370-5. 2010
    ..We prospectively evaluated the efficacy and toxicity of early 3-dimensional conformal radiotherapy (3D-CRT) for patients with unresectable hepatocellular carcinoma (HCC) after incomplete transcatheter arterial chemoembolization (TACE)...
  9. doi Ribavirin dose and treatment outcome of Korean patients with genotype 1 chronic hepatitis C
    Dong Hyun Sinn
    Department of Medicine, Samsung Medical Center, Seoul, South Korea
    Hepatogastroenterology 59:1-6. 2012
    ..The current recommendation of ribavirin dose for the treatment of chronic hepatitis C is based on study results of Western patients, and might not be optimal for Korean patients because of different body frames...
  10. ncbi Milan criteria are useful predictors for favorable outcomes in hepatocellular carcinoma patients undergoing liver transplantation after transarterial chemoembolization
    Do Young Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, 135 710, Seoul, South Korea
    World J Gastroenterol 12:6992-7. 2006
    ..To evaluate whether the Milan criteria are useful in patients with hepatocellular carcinoma (HCC) who received transarterial chemoembolization (TACE) before liver transplantation (LT)...
  11. ncbi Combined hepatectomy and radiofrequency ablation for multifocal hepatocellular carcinomas: long-term follow-up results and prognostic factors
    Dongil Choi
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul, 135 710, Republic of Korea
    Ann Surg Oncol 14:3510-8. 2007
    ..We evaluated the long-term survival results and safety of combined hepatectomy and radiofrequency ablation (RFA) in patients with HCCs and assessed the prognostic factors affecting their survival...
  12. doi Viral response at 6 months is associated with treatment outcome of adefovir add-on therapy for lamivudine-resistance
    Yu Jin Kim
    Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
    J Gastroenterol Hepatol 27:1454-60. 2012
    ..Adefovir add-on therapy is recommended for patients infected with lamivudine-resistant hepatitis B virus (HBV). We aimed to describe the long-term treatment outcome and predictors for good response of adefovir add-on therapy...
  13. pmc Long-term results of percutaneous ethanol injection for the treatment of hepatocellular carcinoma in Korea
    Yon Mi Sung
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 7:187-92. 2006
    ..To evaluate the long-term follow-up results of percutaneous ethanol injection (PEI) for the treatment of hepatocellular carcinoma (HCC) in Korea...
  14. doi Clevudine-induced viral response, associated with continued reduction of HBsAg titer, was durable after the withdrawal of therapy
    Hyo Suk Lee
    Seoul National University Hospital, Seoul, Korea
    J Gastroenterol 46:410-4. 2011
    ..This study was conducted to evaluate the durability of clevudine-induced viral response after the withdrawal of treatment...
  15. ncbi Percutaneous radiofrequency ablation for recurrent hepatocellular carcinoma after hepatectomy: long-term results and prognostic factors
    Dongil Choi
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul, 135 710, Korea
    Ann Surg Oncol 14:2319-29. 2007
    ....
  16. doi Frequency and risk factors of renal impairment during long-term adefovir dipivoxil treatment in chronic hepatitis B patients
    Yu Jin Kim
    Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
    J Gastroenterol Hepatol 27:306-12. 2012
    ..There are insufficient data on renal safety during long-term adefovir dipivoxil (ADV) treatment. We aimed to elucidate the incidence and risk factors of renal impairment in chronic hepatitis B (CHB) patients treated with ADV...
  17. pmc Long-term outcome of preoperative transarterial chemoembolization and hepatic resection in patients with hepatocellular carcinoma
    Ja Young Kang
    Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 16:383-8. 2010
    ..The long-term outcome of HCC patients receiving TACE prior to hepatic resection is uncertain...
  18. doi Defining virologic relapse in chronic hepatitis B
    Kyung Hee Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, Korea
    Dig Dis Sci 56:2432-8. 2011
    ..The aim of this study was to see the effectiveness of these two definitions..
  19. ncbi Percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma as a first-line treatment: long-term results and prognostic factors in a large single-institution series
    Dongil Choi
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul, 135 710, South Korea
    Eur Radiol 17:684-92. 2007
    ..Percutaneous RFA can be used successfully as a first-line treatment modality for early-stage HCCs. Child-Pugh class, age, and AFP level before RFA were significant prognostic predictors of long-term survival...
  20. doi Steatosis among living liver donors without evidence of fatty liver on ultrasonography: potential implications for preoperative liver biopsy
    Joon Seong Ahn
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Transplantation 95:1404-9. 2013
    ..We evaluate the prevalence and risk factors for steatosis in living liver donors with normal serum aminotransferase levels and without fatty liver on ultrasonography (US-negative)...
  21. ncbi Clinical features and prognosis of hepatocellular carcinoma in young patients from a hepatitis B-endemic area
    Jeong Hwan Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Gastroenterol Hepatol 21:588-94. 2006
    ..However, the clinical features of young HCC patients have not been fully studied. In the present study, we investigated the prevalence, clinical characteristics and prognosis of young HCC patients...
  22. ncbi The clinical value of 18F-FDG PET/CT for investigating unexplained serum AFP elevation following interventional therapy for hepatocellular carcinom
    A Reum Han
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Hepatogastroenterology 56:1111-6. 2009
    ....
  23. ncbi Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression
    Byung Chul Yoo
    Sungkyunkwan University Samsung Medical Center, Seoul, South Korea
    Hepatology 46:1041-8. 2007
    ..0006). ALT normalization in the clevudine group was well-maintained during the post-treatment follow-up period. The incidence of adverse events was similar in the 2 groups. No resistance to clevudine was detected during treatment...
  24. doi Pre-s mutation is a significant risk factor for hepatocellular carcinoma development: a long-term retrospective cohort study
    Dong Hyun Sinn
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, South Korea
    Dig Dis Sci 58:751-8. 2013
    ..Several cross-sectional studies have shown an association between pre-S mutation and hepatocellular carcinoma (HCC)...
  25. doi Clinicopathologic characteristics and long-term prognosis of scirrhous hepatocellular carcinoma
    Jin Hee Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Dig Dis Sci 57:1698-707. 2012
    ..Clinicopathologic features and long-term outcomes in patients with scirrhous hepatocellular carcinoma (S-HCC) are not fully defined...
  26. pmc A clinical predictor of varices and portal hypertensive gastropathy in patients with chronic liver disease
    Yang Won Min
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Mol Hepatol 18:178-84. 2012
    ....
  27. ncbi The correlation of hepatitis B virus pre-S mutation with cellular oxidative DNA damage in hepatocellular carcinoma
    Geum Youn Gwak
    Department of Medicine and Digestive Disease Research Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Hepatogastroenterology 55:2028-32. 2008
    ..Therefore, we investigated the correlation of HBV pre-S mutation with ER stress and cellular oxidative DNA damage in HBV-related HCC patients...
  28. pmc Seroprevalence of anti-HAV among patients with chronic viral liver disease
    Hyun Chin Cho
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, South Korea
    World J Gastroenterol 17:236-41. 2011
    ..To investigate the current seroprevalence of hepatitis A virus (HAV) antibodies in patients with chronic viral liver disease in Korea. We also tried to identify the factors affecting the prevalence of HAV antibodies...
  29. ncbi A phase II study of oxaliplatin in combination with doxorubicin as first-line systemic chemotherapy in patients with inoperable hepatocellular carcinoma
    Ji Eun Uhm
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul, 135 710, South Korea
    Cancer Chemother Pharmacol 63:929-35. 2009
    ..We designed a phase II trial of the combination with oxaliplatin and doxorubicin for patients with unresectable HCC to evaluate the overall response rate (ORR) and the toxicity...
  30. doi [Virologic response to adefovir dipivoxil monotherapy is not durable in HBeAg-positive, lamivudine-resistant chronic hepatitis B patients]
    Hyun Wook Jung
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 15:52-8. 2009
    ..However, little is known about the durability of the virologic response to adefovir in LAMV-R CHB patients...
  31. ncbi Analysis of risk factors associated with early multinodular recurrences after hepatic resection for hepatocellular carcinoma
    Jung Ho Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    Am J Surg 192:29-33. 2006
    ..We conducted this retrospective study to investigate the risk factors of early multinodular (ie, 10 nodules within 6 months of surgery) recurrence in hepatocellular carcinoma...
  32. doi Clinical parameters predictive of outcomes in sorafenib-treated patients with advanced hepatocellular carcinoma
    Ju Yeon Cho
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Liver Int 33:950-7. 2013
    ..However, clinical parameters that may predict the treatment outcomes in sorafenib-treated advanced HCC patients remains unknown...
  33. pmc Comparison of usefulness of clinical diagnostic criteria for hepatocellular carcinoma in a hepatitis B endemic area
    So Young Bae
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Mol Hepatol 18:185-94. 2012
    ..We compared the accuracy and usefulness of clinical diagnostic criteria for hepatocellular carcinoma in a hepatitis B virus (HBV)-endemic area...
  34. ncbi The correlation of hepatitis B virus pre-S mutation with mitochondrial D-loop mutations and common deletions in hepatocellular carcinoma
    Geum Youn Gwak
    Department of Medicine and Digestive Disease Research Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Hepatogastroenterology 58:522-8. 2011
    ..We investigated the correlation of HBV pre-S mutation with the sites and frequencies of mtDNA mutations in HCC patients...
  35. ncbi Is there any clinical or radiologic feature as a preoperative marker for differentiating mass-forming pancreatitis from early-stage pancreatic adenocarcinoma?
    Hyuk Lee
    Department of Medicine, Sungkyunkwan University School of Medicine Seoul, Korea
    Hepatogastroenterology 54:2134-40. 2007
    ..The purpose of the present study was to define the differential feature of focal mass-forming pancreatitis and malignant mass using aspects of clinical, laboratory and imaging features on pancreatogram or computed tomography (CT)...
  36. doi Effect of balloon-occluded retrograde transvenous obliteration on the natural history of coexisting esophageal varices
    Yong Sung Choi
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Gastroenterol 42:974-9. 2008
    ..The aim of this study was to determine whether the natural history of coexisting EV is affected by BRTO...
  37. ncbi Older donor allografts are associated with poor patient survival after living donor liver transplantation for hepatitis B virus-related liver diseases
    Do Young Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Liver Int 27:260-7. 2007
    ..The significance of donor age in living donor liver transplantation (LDLT) for hepatitis B virus (HBV) infection has not been fully evaluated...
  38. pmc Tenofovir rescue therapy for chronic hepatitis B patients after multiple treatment failures
    Yu Jin Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, South Korea
    World J Gastroenterol 18:6996-7002. 2012
    ..To evaluate the efficacy and safety of tenofovir disoproxil fumarate (TDF) for chronic hepatitis B (CHB) patients after multiple failures...
  39. ncbi Clevudine therapy for 24 weeks further reduced serum hepatitis B virus DNA levels and increased ALT normalization rates without emergence of viral breakthrough than 12 weeks of clevudine therapy
    Kwan Sik Lee
    Yonsei University Hospital, Seoul, Korea
    Intervirology 50:296-302. 2007
    ..The objectives of the study were to evaluate the safety and antiviral activity of 24-week treatment with clevudine 30 mg in HBeAg(+) chronic hepatitis B patients. Biochemical and serological responses were also assessed...
  40. doi Ten-year outcomes of percutaneous radiofrequency ablation as first-line therapy of early hepatocellular carcinoma: analysis of prognostic factors
    Young Sun Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    J Hepatol 58:89-97. 2013
    ..The aim was to assess 10-year outcomes of radiofrequency ablation as a first-line therapy of early-stage hepatocellular carcinoma with an analysis of prognostic factors...
  41. ncbi Disease progression and the risk factor analysis for chronic hepatitis C
    Dong Hyun Sinn
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Liver Int 28:1363-9. 2008
    ..The present study aimed to assess the incidence of advanced cirrhotic complications and to identify the risk factors associated with such complications in chronic hepatitis C...
  42. ncbi [Antiviral efficacy of lamivudine/adefovir combination therapy in chronic hepatitis b patients with resistance to lamivudine and adefovir consecutively]
    Hyun Joo Suh
    Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Gangnam Gu, Seoul, Korea
    Korean J Gastroenterol 53:305-10. 2009
    ..The aim of this study was to elucidate the antiviral efficacy of lamivudine (LMV)-adefovir (ADV) combination therapy in chronic hepatitis B patients who showed resistance to LMV and ADV consecutively...
  43. doi [Natural history of gastric varices and risk factors for bleeding]
    Choong Hyeon Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 14:331-41. 2008
    ..The aim of this study was to elucidate the natural history of GV bleeding in Korean patients...
  44. pmc Virological response to adefovir monotherapy and the risk of adefovir resistance
    Dong Hyun Sinn
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 135 710 Seoul, South Korea
    World J Gastroenterol 17:3526-30. 2011
    ..To evaluate virological response to adefovir (ADV) monotherapy and emergence of ADV-resistant mutations in lamivudine (LAM)-resistant chronic hepatitis B patients...
  45. ncbi Radiation therapy for abdominal lymph node metastasis from hepatocellular carcinoma
    Young Je Park
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Gangnam Gu, Seoul 135 710, Korea
    J Gastroenterol 41:1099-106. 2006
    ..We report the results of radiotherapy for abdominal lymph node metastasis from hepatocellular carcinoma (HCC)...
  46. ncbi Screening for extrahepatic metastases by additional staging modalities is required for hepatocellular carcinoma patients beyond modified UICC stage T1
    Jieun Yi
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Hepatogastroenterology 60:328-32. 2013
    ..However, there is limited data about when and how to screen EHM for newly diagnosed HCC patients, especially for patients without symptoms or signs of EHM...
  47. ncbi [Clinical features and predictive factors of acute hepatitis A complicated with acute kidney injury]
    Jin Hee Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Gastroenterol 56:359-64. 2010
    ..we assessed the clinical features and prognosis of acute viral hepatitis A (AHA) complicated with acute kidney injury (AKI) and elucidated predictive factors for AKI in patients with AHA...
  48. ncbi Analysis of the core gene of hepatitis B virus in Korean patients
    Hyung Joon Kim
    Department of Internal Medicine, Chung Ang University Hospital, Seoul, South Korea
    Liver Int 27:633-8. 2007
    ....
  49. ncbi [Peginterferon alfa-2a plus ribavirin for initial treatment of chronic hepatitis C in Korea]
    Hyuk Lee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 12:31-40. 2006
    ..We evaluated the efficacy and safety of administering peginterferon alfa-2a plus ribavirin in native Korean patients with chronic hepatitis C...
  50. ncbi Comparing the outcomes of radiofrequency ablation and surgery in patients with a single small hepatocellular carcinoma and well-preserved hepatic function
    Sung Noh Hong
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Korea
    J Clin Gastroenterol 39:247-52. 2005
    ..To compare the efficacy of radiofrequency ablation (RFA) and surgical resection in a group of patients with a Child-Pugh score of 5 and a single HCC less than 4 cm in diameter...
  51. pmc Prognostic index for portal vein tumor thrombosis in patients with hepatocellular carcinoma treated with radiation therapy
    Jeong Il Yu
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 26:1014-22. 2011
    ..0%, 17.3% vs 70.1%, 40.8%, respectively, P < 0.001). The PITH scoring model, proposed in the current study in HCC patients with PVTT, reliably predict overall survival...
  52. doi Mortality after surgery in patients with liver cirrhosis: comparison of Child-Turcotte-Pugh, MELD and MELDNa score
    Hyun Chin Cho
    Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Eur J Gastroenterol Hepatol 23:51-9. 2011
    ....
  53. doi [Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation]
    Se Hoon Oh
    Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
    Korean J Hepatol 15:362-9. 2009
    ....
  54. ncbi Photodynamic therapy for bile duct invasion of hepatocellular carcinoma
    Sunha Bahng
    Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Photochem Photobiol Sci 12:439-45. 2013
    ..There was no 30-day mortality, and the mean survival was 140.5 days. PDT controlled hemobilia associated with bile duct invasion of HCC and could be an effective treatment option in these patients...
  55. ncbi [Efficacy and safety of adefovir dipivoxil in patients with decompensated liver cirrhosis with Lamivudine resistance compared to patients with compensated liver disease]
    Won Moon
    Department of Medicine, Gastrointestinal Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 11:125-34. 2005
    ..We retrospectively evaluated the efficacy and safety of adefovir dipivoxil in patients with decompensated liver cirrhosis with lamivudine resistance, and we compared this to the patients having compensated liver disease...
  56. ncbi The feasibility of combined transcatheter arterial chemoembolization and radiotherapy for advanced hepatocellular carcinoma
    Ju Yeon Cho
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Liver Int 34:795-801. 2014
    ..This study aimed to investigate the feasibility of combined transarterial chemoembolization and radiotherapy (TACE+RT) in comparison with sorafenib for advanced hepatocellular carcinoma (HCC)...
  57. ncbi Clinicopathologic features and prognosis of combined hepatocellular cholangiocarcinoma
    Kwang Cheol Koh
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon dong 50, Kangnam Ku, Seoul, Korea 135 710
    Am J Surg 189:120-5. 2005
    ..Clinicopathologic features and prognosis of combined hepatocellular cholangiocarcinoma (HCC-CC) have not been established...
  58. doi The efficacy of high-dose 3-dimensional conformal radiation therapy in patients with small hepatocellular carcinoma not eligible for other local modalities
    Do Hoon Lim
    Department of Radiation Oncology, Samsung Medical Center, Seoul, Korea
    Am J Clin Oncol 36:162-6. 2013
    ..To analyze the efficacy and toxicity of high-dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with small hepatocellular carcinoma (HCC) not eligible for other local modalities...
  59. doi Ultrasonographically detected non-alcoholic fatty liver disease is an independent predictor for identifying patients with insulin resistance in non-obese, non-diabetic middle-aged Asian adults
    Dong Hyun Sinn
    Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Am J Gastroenterol 107:561-7. 2012
    ....
  60. pmc Scheduled interval trans-catheter arterial chemoembolization followed by radiation therapy in patients with unresectable hepatocellular carcinoma
    Jeong Il Yu
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 27:736-43. 2012
    ..Other toxicities were manageable. The median survival was 14.7 months. There was a significant difference in overall survival according to the response to START (P < 0.001). In conclusion, START is safe and feasible...
  61. pmc Clinical course of sub-centimeter-sized nodules detected during surveillance for hepatocellular carcinoma
    Yang Won Min
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, South Korea
    World J Gastroenterol 18:2654-60. 2012
    ..To evaluate the outcome of sub-centimeter-sized nodules (SCSNs) detected during surveillance for hepatocellular carcinoma (HCC) in patients at risk...
  62. doi Clinical significance of core gene mutations during the course of genotype C chronic hepatitis B virus infection
    Dong Ho Lee
    Department of Medicine, Samsung Medical Center, Seoul, Korea
    Hepatogastroenterology 58:1643-7. 2011
    ..The aim of this study was to investigate the association of HBV core gene mutations with disease severity in HBV-infected patients...
  63. ncbi The efficacy of combined transarterial chemoembolization and 3-dimensional conformal radiotherapy for hepatocellular carcinoma with main portal vein thrombosis
    Moon Kyung Park
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, 135 710 Seoul, South Korea
    Hepatogastroenterology 57:801-6. 2010
    ..The goal of this study was to evaluate the efficacy of combined therapy with TAE and 3-dimensional conformal radiotherapy (3D-CRT) for HCC with main portal vein thrombosis (MPVT)...
  64. pmc Long-term treatment outcomes for autoimmune hepatitis in Korea
    Jae Sook Kil
    Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
    J Korean Med Sci 25:54-60. 2010
    ..This suggests that long-term immunosuppressive therapy may be particularly important for treatment of Korean patients...
  65. ncbi [The age-specific seroprevalence of hepatitis A virus antibody in Korea]
    Young Bong Song
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Hepatol 13:27-33. 2007
    ..Recently, the prevalence of hepatitis A in young adults has been steadily increasing in Korea. This study is to investigate the age-specific seroprevalence of hepatitis A virus in Korea...
  66. doi Predictive factors of gastroduodenal toxicity in cirrhotic patients after three-dimensional conformal radiotherapy for hepatocellular carcinoma
    Haeyoung Kim
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Radiother Oncol 93:302-6. 2009
    ..To identify predictive factors for the development of gastroduodenal toxicity (GDT) in cirrhotic patients treated with three-dimensional conformal radiotherapy (3D-CRT) for hepatocellular carcinoma (HCC)...
  67. doi Salvage treatment with hypofractionated radiotherapy in patients with recurrent small hepatocellular carcinoma
    Sun Hyun Bae
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 82:e603-7. 2012
    ....
  68. doi Change in contrast enhancement of HCC on 1-month follow-up CT after local radiotherapy: an early predictor of final treatment response
    Eun Young Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam Ku, Seoul 135 710, Republic of Korea
    Eur J Radiol 72:440-6. 2009
    ..The purpose of this study was to evaluate the change in contrast enhancement of HCC on 1-month follow-up CT after local radiotherapy (RT) as an early predictor of final treatment response...
  69. pmc A comparison of 48-week treatment efficacy between clevudine and entecavir in treatment-naïve patients with chronic hepatitis B
    Su Rin Shin
    Department of Medicine, Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea
    Hepatol Int 5:664-70. 2011
    ..Clevudine and entecavir are currently available in Korea as antiviral drugs against chronic hepatitis B (CHB). We aimed to compare the efficacy of clevudine and entecavir therapy...
  70. pmc Prediction of complete necrosis of hepatocellular carcinoma treated with transarterial chemoembolization prior to liver transplantation
    Sue Jin Kim
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Gut Liver 3:285-91. 2009
    ..However, its usefulness has not been fully investigated in the explanted liver...
  71. ncbi Factors associated with natural seroclearance of hepatitis B surface antigen and prognosis after seroclearance: a prospective follow-up study
    Jeong Hwan Kim
    Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
    Hepatogastroenterology 55:578-81. 2008
    ..4-2% in western countries, this is not well known in Korea. This study aimed to elucidate the rate of natural HbsAg seroclearance, factors associated with seroclearance and prognosis after seroclearance...
  72. pmc Antiviral therapy in patients after treatment for hepatitis C-related hepatocellular carcinoma
    Su Rin Shin
    Department of Medicine, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea
    Gut Liver 5:77-81. 2011
    ..We evaluated the efficacy and safety of antiviral therapy following treatment for hepatitis C-related HCC...
  73. pmc A low viral load predicts a higher initial virologic response to adefovir in patients with Lamivudine-resistant chronic hepatitis B
    Su Rin Shin
    Department of Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Gut Liver 4:530-6. 2010
    ..However, not all patients who face virologic breakthrough during LAM treatment respond to ADV. The aim of this study was to determine the factors associated with efficacy of ADV in LAM-resistant hepatitis B patients...
  74. pmc The Seroconversion Rate of Hepatitis A Virus Vaccination among Patients with Hepatitis B Virus-Related Chronic Liver Disease in Korea
    Hyun Chin Cho
    Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Gut Liver 5:217-20. 2011
    ..The aim of this study was to evaluate the seroconversion rate of a hepatitis A virus (HAV) vaccination in patients with hepatitis B virus (HBV)-related chronic liver disease (CLD)...
  75. ncbi [A case of hepatocellular carcinoma complicating cardiac cirrhosis caused by constrictive pericarditis]
    Pil Sang Song
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Gastroenterol 45:436-40. 2005
    ..To our knowledge, this is the first case of HCC complicating cardiac cirrhosis in Korea...
  76. ncbi Rapid quantitative determination of L-FMAU-TP from human peripheral-blood mononuclear cells of hepatitis B virus-infected patients treated with L-FMAU by ion-pairing, reverse-phase, liquid chromatography/electrospray tandem mass spectrometry
    Jaeick Lee
    Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, Chungryang, Seoul, Korea
    Ther Drug Monit 28:131-7. 2006
    ..The terminal half-life of L-FMAU-TP in PBMCs after drug cessation was estimated to be 15.6 days...
  77. pmc Comparison of the Clinical Features of Hepatitis A between HBsAg-Positive and HBsAg-Negative Patients
    Kwang Min Kim
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Gut Liver 5:500-5. 2011
    ..The aim of this study was to determine the influence of the presence of hepatitis B surface antigen (HBsAg) on the severity of acute hepatitis A...
  78. ncbi [The prevalence and clinical significance of precore and core promoter mutations in Korean patients with chronic hepatitis B virus infection]
    Hyung Joon Kim
    Department of Gastroenterology, College of Medicine, Chung Ang University, Seoul, Korea
    Taehan Kan Hakhoe Chi 8:149-56. 2002
    ..The aims of this study were to determine the prevalence of precore and core promoter mutations and their relationships to hepatitis B e antigen (HBeAg) status, viral replication level, and severity of liver disease in Korea...
  79. ncbi Balloon-occluded retrograde transvenous obliteration of gastric varices: outcomes and complications in 49 patients
    Sung Ki Cho
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon dong 50, Kangnam Ku, Seoul 135 710, Korea
    AJR Am J Roentgenol 189:W365-72. 2007
    ..Our aim was to evaluate the clinical outcomes, techniques, and complications of balloon-occluded retrograde transvenous obliteration for treating gastric varices with spontaneous gastrosystemic shunts...
  80. ncbi [A prospective study on the prevalence and clinical significance of autoantibodies in patients with suspected nonalcoholic fatty liver disease]
    Dae Hyeon Cho
    Department of Medicine, Samsung Medical Center, Seoul, Korea
    Korean J Hepatol 11:261-7. 2005
    ..However, there has been no study on the prevalence and significance of autoantibodies in the patients with clinically suspected NAFLD in Korea, where hepatitis B is endemic and autoimmune hepatitis is relatively uncommon...
  81. pmc Superior long-term outcomes after surgery in child-pugh class a patients with single small hepatocellular carcinoma compared to radiofrequency ablation
    Won Kyoung Yun
    Department of Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea
    Hepatol Int 5:722-9. 2011
    ..There are insufficient data comparing long-term prognoses after radiofrequency ablation (RFA) and surgery...
  82. ncbi Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B
    Byung Chul Yoo
    Samsung Medical Center, Sungkyunkwan University, and Yonsei University Hospital, Seoul, Korea
    Hepatology 45:1172-8. 2007
    ..The incidence of adverse events (AEs) was similar between the clevudine group and the placebo group. No resistance to clevudine was detected with 24 weeks of administration of drug...
  83. ncbi [Risk factors of morbidity and mortality following surgical resection for hepatocellular carcinoma]
    Wan Wook Kim
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea
    Korean J Hepatol 10:51-61. 2004
    ..Recently, mortality following surgical resection for hepatocellular carcinoma has been reduced significantly. Morbidity, however, is still significant. This study evaluated the risk factors leading to morbidity and mortality...
  84. pmc Glycyrrhizin attenuates HMGB1-induced hepatocyte apoptosis by inhibiting the p38-dependent mitochondrial pathway
    Geum Youn Gwak
    Department of Medicine, Samsung Medical Center, Sugnkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, 135 710 Seoul, South Korea
    World J Gastroenterol 18:679-84. 2012
    ..To examine how high-mobility group box 1 (HMGB1) regulates hepatocyte apoptosis and, furthermore, to determine whether glycyrrhizin (GL), a known HMGB1 inhibitor, prevents HMGB1-induced hepatocyte apoptosis...
  85. ncbi The relationship between apolipoprotein E polymorphism, lipoprotein (a) and fatty liver disease
    Moon Hee Yang
    Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Hepatogastroenterology 52:1832-5. 2005
    ..The purpose of this study was to investigate the relationship between the apo E genotype, plasma Lp(a) level, and fatty liver...
  86. ncbi Prognostic significance of p53 overexpression after hepatic resection of hepatocellular carcinoma
    Chang Okh Sung
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, Seoul, Korea
    Korean J Gastroenterol 45:425-30. 2005
    ..The aims of the present study were to examine the correlations between p53 overexpression and the clinicopathologic parameters of HCCs, and to determine the prognostic significance of p53 overexpression in HCC...
  87. ncbi Diaphragmatic weakness after transcatheter arterial chemoembolization of inferior phrenic artery for treatment of hepatocellular carcinoma
    Sung Wook Shin
    Department of Radiology and Center for Imaging Sciences, Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Kangnam Ku, Seoul 135 710, Korea
    Radiology 241:581-8. 2006
    ..To prospectively assess the diaphragmatic anatomic and functional consequences of transcatheter arterial chemoembolization (TACE) of the inferior phrenic artery in patients with hepatocellular carcinoma...
  88. ncbi Positive positron emission tomography scan in sarcoidosis and two challenging cases of metastatic cancer. CASE 2. Hepatocellular carcinoma with metastasis to the breast
    Ji Young Rhee
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Oncol 23:8908-9. 2005
  89. ncbi [Early diagnosis and improved survival with screening for hepatocellular carcinoma]
    Chung Mee Youk
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Taehan Kan Hakhoe Chi 9:116-23. 2003
    ..The purpose of this study was to determine whether screening can achieve early diagnosis and survival benefits...
  90. pmc Management of chronic hepatitis B with nucleoside or nucleotide analogues: a review of current guidelines
    Moon Seok Choi
    Division of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Gut Liver 4:15-24. 2010
    ..A review of the past and current guidelines for the management of CH-B would be useful for evaluating the current status of management of the disease and to identify better solutions for improving the outcome of patients with CH-B...
  91. pmc Promoter methylation of E-cadherin in hepatocellular carcinomas and dysplastic nodules
    Ghee Young Kwon
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 20:242-7. 2005
    ..And the promoter methylation of E-cadherin in HCC was found to be significantly correlated with microvascular invasion and recurrence...
  92. ncbi Phase II study of doxorubicin and cisplatin in patients with metastatic hepatocellular carcinoma
    Jeeyun Lee
    Division of Hematology Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 135 710, Seoul, Korea
    Cancer Chemother Pharmacol 54:385-90. 2004
    ....
  93. ncbi Local radiotherapy for patients with unresectable hepatocellular carcinoma
    Won Park
    Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Int J Radiat Oncol Biol Phys 61:1143-50. 2005
    ..To evaluate the response to local radiotherapy (RT) for unresectable hepatocellular carcinoma (HCC) and to analyze the dose-response relationship and the treatment-related morbidities...
  94. ncbi Liver abscess after percutaneous radiofrequency ablation for hepatocellular carcinomas: frequency and risk factors
    Dongil Choi
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul 135 710, South Korea
    AJR Am J Roentgenol 184:1860-7. 2005
    ..The purpose of this study was to clarify the frequency and risk factors of liver abscess formation after percutaneous radiofrequency ablation in patients with hepatocellular carcinoma...
  95. ncbi Cyclin E, p27 and mutant p53 do not predict the prognosis in AJCC stage II colorectal carcinomas
    Yun Jeong Lim
    Department of Internal Medicine, Sungkyunkwan University School of Medicine, Center for Health Promotion, Samsung Medical Center, Seoul 135 710, Korea
    Korean J Gastroenterol 44:314-20. 2004
    ..Since the clinical significance of the expression of the three proteins in colorectal carcinomas is still controversial, we evaluated the prognostic value of the expression of cyclin E, p27 and mutant p53 in stage II colorectal cancer...
  96. pmc Correlation of mutation and immunohistochemistry of p53 in hepatocellular carcinomas in Korean people
    Shi Nae Lee
    Department of Pathology, Ewha Womans University College of Medicine, Seoul, Korea
    J Korean Med Sci 17:801-5. 2002
    ....
  97. ncbi Three-dimensional conformal radiotherapy for portal vein thrombosis of hepatocellular carcinoma
    Dae Yong Kim
    Research Institute and Hospital, National Cancer Center, Gyeonggi, Korea
    Cancer 103:2419-26. 2005
    ..The authors evaluated the impact of radiotherapy (RT) for PVT of HCC and analyzed the dose-response relation between RT and PVT...
  98. doi UGT1A7 haplotype is associated with an increased risk of hepatocellular carcinoma in hepatitis B carriers
    Sun Young Kong
    Department of Laboratory Medicine, Center for Clinical Services, Research Institute and Hospital, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang si, Gyeonggi do 410 769, Korea
    Cancer Sci 99:340-4. 2008
    ..45 [95% CI; 1.03-2.03] and 4.95 [95% CI; 1.75-13.98], respectively). The results of this study show that the UGT1A7 haplotype is a suitable susceptibility marker for the development of HCC in hepatitis B carriers...
  99. ncbi A 12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B
    Hyo Suk Lee
    Seoul National University Hospital, South Korea
    Hepatology 43:982-8. 2006
    ....
  100. ncbi A phase II dose-escalating trial of clevudine in patients with chronic hepatitis B
    Patrick Marcellin
    Service d Hepatologie, Hopital Beaujon, Clichy, France
    Hepatology 40:140-8. 2004
    ..The pharmacokinetic profile of clevudine was proportional to the dose. In conclusion, these results demonstrate the tolerability and potent activity of clevudine in HBV-infected patients and support further clinical study...