Moon Ho Son
Affiliation: Research Laboratories
- The development of non-peptide glucagon-like peptide-1 receptor agonist for the treatment of type 2 diabetesHo Sang Moon
Research Center, Dong A Pharm Co, Ltd, Yongin 446 905, Korea
Arch Pharm Res 34:1041-3. 2011..In this report, the authors provide a review on the development of non-peptide GLP-1 receptor agonists and introduce a novel agonist DA-15864...
- Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: synthesis, SAR and biological evaluationHeung Jae Kim
Dong A Pharm Co, Ltd, 47 5, Sanggal dong, Giheung gu, Yongin si, Gyeonggi do 446 905, Republic of Korea
Bioorg Med Chem Lett 22:5545-9. 2012..Several series of β-amino amide containing piperazine derivatives have been prepared and evaluated as a inhibitor of DPP4. Finally compound 5m was selected for further evaluation...
- PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivoMi Kyung Kim
Research Center, Dong A Pharm Co, Ltd, Sanggal dong, Giheung gu, Yongin si, Gyeonggi Do, Republic of Korea
Eur J Pharmacol 595:119-25. 2008..And its balanced activities may render PAR-5359 as a pharmacological tool in elucidating the complex roles of PPARalpha/gamma dual agonists...