Hyuk Jin Cha

Summary

Affiliation: Pochon CHA University
Country: Korea

Publications

  1. ncbi Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response
    Hyukjin Cha
    Department of Biochemistry, Georgetown University, Washington, District of Columbia 20057 1468, USA
    Cancer Res 70:4112-22. 2010
  2. ncbi Wip1-expressing feeder cells retain pluripotency of co-cultured mouse embryonic stem cells under leukemia inhibitory factor-deprivated condition
    Jin Ju Kim
    Department of Biomedical Science, College of Life Science, CHA University, Pochon, 487 010, Korea
    Arch Pharm Res 33:1253-60. 2010
  3. ncbi p16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation
    Mi Ok Lee
    Department of Biomedical Science, Bundang CHA Hospital, College of Medicine, CHA University, Seoul, Korea
    J Thorac Oncol 6:423-31. 2011
  4. ncbi Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling
    Young Cha
    Department of Biomedical Science, College of Life Science, CHA University, Pochon si Gyeonggi do, Korea
    Stem Cells 28:1476-86. 2010
  5. ncbi Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase
    Julie M Lowe
    Department of Biochemistry and Molecular and Cellular Biology, Lombardi Comprehensive Center, Georgetown University, Washington, DC 20057, USA
    J Biol Chem 285:5249-57. 2010

Collaborators

  • Dmitry V Bulavin
  • Kwang Soo Kim
  • Mi Ok Lee
  • Albert J Fornace
  • Jin Ju Kim
  • Young Cha
  • Bo Hyun Moon
  • Julie M Lowe
  • Eun Kyung Kim
  • Hyeon Jae Lee
  • Jin Hyung Heo
  • Sang Ho Cho
  • Mi Ae Kim
  • Seung Hyuk Lee
  • Hye Cheol Jeong
  • Ji Hyun Lee
  • Henghong Li
  • Ji Seon Lee
  • Qian Yang
  • Seun Hyun Song
  • Kyung Ah Lee
  • Kyung Soon Park
  • Hee Jin Ahn
  • Hye Jin Lee

Detail Information

Publications5

  1. ncbi Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response
    Hyukjin Cha
    Department of Biochemistry, Georgetown University, Washington, District of Columbia 20057 1468, USA
    Cancer Res 70:4112-22. 2010
    ..Taken together, our studies show that Wip1 is an important mammalian phosphatase for gamma-H2AX and shows an additional mechanism for Wip1 in the tumor surveillance network...
  2. ncbi Wip1-expressing feeder cells retain pluripotency of co-cultured mouse embryonic stem cells under leukemia inhibitory factor-deprivated condition
    Jin Ju Kim
    Department of Biomedical Science, College of Life Science, CHA University, Pochon, 487 010, Korea
    Arch Pharm Res 33:1253-60. 2010
    ..These results indicate that genetically engineered feeder cells such as Wip1 expressing cell lines, are alternative strategy for the optimization of maintenance and expansion of mouse embryonic stem cells...
  3. ncbi p16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation
    Mi Ok Lee
    Department of Biomedical Science, Bundang CHA Hospital, College of Medicine, CHA University, Seoul, Korea
    J Thorac Oncol 6:423-31. 2011
    ..p38 mitogen-activated protein kinase (MAPK), which reportedly plays a crucial role as a tumor suppressor, is activated in number of lung adenocarcinomas, which is seemingly at odds with its role as a tumor suppressor...
  4. ncbi Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling
    Young Cha
    Department of Biomedical Science, College of Life Science, CHA University, Pochon si Gyeonggi do, Korea
    Stem Cells 28:1476-86. 2010
    ....
  5. ncbi Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase
    Julie M Lowe
    Department of Biochemistry and Molecular and Cellular Biology, Lombardi Comprehensive Center, Georgetown University, Washington, DC 20057, USA
    J Biol Chem 285:5249-57. 2010
    ....