Research Topics
Genomes and Genes | Joo Young KimSummaryAffiliation: National Cancer Center Country: Korea Publications
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Detail Information
Publications
High control rate for lymph nodes in cervical cancer treated with high-dose radiotherapy using helical tomotherapyY J Kim
Research Institute and Hospital, _National Cancer Center, Goyang si, Gyeonggi Do, South Korea
Technol Cancer Res Treat 12:45-51. 2013..The treatment of bulky lymphadenopathy using helical tomotherapy in advanced cervical cancer is highly effective and has acceptable toxicity...
The bioreductive agent RH1 and gamma-irradiation both cause G2/M cell cycle phase arrest and polyploidy in a p53-mutated human breast cancer cell lineJoo Young Kim
Cancer Research UK Group of Experimental Radiation Oncology, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK
Int J Radiat Oncol Biol Phys 58:376-85. 2004..Thus, we investigated the effect of RH1 and gamma-irradiation on the formation of polyploid cells and a sub-G1 population (as a measure of apoptosis) in relation to the G2/M cell cycle block...
Low initial human papilloma viral load implicates worse prognosis in patients with uterine cervical cancer treated with radiotherapyJoo Young Kim
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
J Clin Oncol 27:5088-93. 2009..The multivariable Cox proportional hazards model was used to adjust for covariates. A relapse-predicting model was constructed to classify three risk groups for disease-free survival (DFS), which were used for internal validation...
Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcomeChong Woo Yoo
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
Radiat Oncol 5:101. 2010..To investigate whether expression of carbonic anhydrase XII (CA12) is associated with histologic grade of the tumors and radiotherapy outcomes of the patients with invasive cervical cancer...
Pelvic lymph node status assessed by 18F-fluorodeoxyglucose positron emission tomography predicts low-risk group for distant recurrence in locally advanced cervical cancer: a prospective studySokbom Kang
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea
Int J Radiat Oncol Biol Phys 79:788-93. 2011..To develop a prediction model to identify a low-risk group for distant recurrence in patients with locally advanced cervical cancer treated by concurrent chemoradiation...
Persistent human papillomavirus DNA is associated with local recurrence after radiotherapy of uterine cervical cancerYong Jung Song
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
Int J Cancer 129:896-902. 2011..In HPV-positive cervical carcinoma treated primarily with radiotherapy, persistent HPV DNA within 24 months after treatment indicates a high risk of local recurrence. Diagnostic accuracy of HPV test was highest at 3 months...
Outcomes and toxicities for the treatment of stage IVB cervical cancerJong Ha Hwang
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, 323 Illsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
Arch Gynecol Obstet 285:1685-93. 2012....
Use of serum squamous cell carcinoma antigen for follow-up monitoring of cervical cancer patients who were treated by concurrent chemoradiotherapySang Min Yoon
Research Institute and Hospital, National Cancer Center, 809 Madu 1 dong, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
Radiat Oncol 5:78. 2010..To investigate the significance of monitoring the levels of the serum squamous cell carcinoma antigen (SCC-Ag) for the detection of recurrent disease in patients with cervical cancer treated by concurrent chemoradiotherapy...
The effect of a contrast agent on proton beam range in radiotherapy planning using computed tomography for patients with locoregionally advanced lung cancerUi Jung Hwang
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea
Int J Radiat Oncol Biol Phys 81:e317-24. 2011..We evaluated the effect of a contrast agent (CA) on proton beam range in a treatment planning system (TPS) for patients with locoregionally advanced lung cancer...
Computed tomography-based high-dose-rate intracavitary brachytherapy for uterine cervical cancer: preliminary demonstration of correlation between dose-volume parameters and rectal mucosal changes observed by flexible sigmoidoscopyWoong Sub Koom
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, South Korea
Int J Radiat Oncol Biol Phys 68:1446-54. 2007..To compare the dose-volume histogram (DVH) parameters obtained by three-dimensional gynecologic brachytherapy planning with the rectosigmoid mucosal changes observed by flexible sigmoidoscopy...
Inter- and intrafractional movement-induced dose reduction of prostate target volume in proton beam treatmentMyonggeun Yoon
Proton Therapy Center, National Cancer Center, Goyang, Republic of Korea
Int J Radiat Oncol Biol Phys 71:1091-102. 2008..To quantify proton radiotherapy dose reduction in the prostate target volume because of the three-dimensional movement of the prostate based on an analysis of dose-volume histograms (DVHs)...
Dose-volumetric parameters of acute esophageal toxicity in patients with lung cancer treated with three-dimensional conformal radiotherapyTae Hyun Kim
Research Institute and Hospital, National Cancer Center, Madu 1-dong, Ilsan-gu, Goyang, Gyeonggi 411-769, South Korea
Int J Radiat Oncol Biol Phys 62:995-1002. 2005..For patients being treated with concurrent chemotherapy, V60 is considered to be a useful parameter predicting the risk of severe AET after conventionally fractionated 3D-CRT for lung cancer...
Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesisBoh Ram Kim
Research Institute and Hospital, National Cancer Center, Ilsandong gu, Goyang si, Gyeonggi Do, Republic of Korea
Cell Signal 24:1406-13. 2012..Taken together, these findings identify DKK-1 as a potential factor in the regulation of CA9 cellular homeostasis and also suggest a new possible role for DKK1-1 in tumorigenesis...
Hypoxia-induced up-regulation of apelin is associated with a poor prognosis in oral squamous cell carcinoma patientsKyun Heo
Research Institute and Hospital, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
Oral Oncol 48:500-6. 2012..Based on these results, we propose that the presence of hypoxia-induced apelin is a new prognostic factor and potential therapeutic target for oral squamous cell carcinoma...
Simultaneous integrated boost intensity-modulated radiotherapy in patients with high-grade gliomasKwan Ho Cho
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Republic of Korea
Int J Radiat Oncol Biol Phys 78:390-7. 2010..We analyzed outcomes of simultaneous integrated boost (SIB) intensity-modulated radiotherapy (IMRT) in patients with high-grade gliomas, compared with a literature review...
A phase II study of hypofractionated proton therapy for prostate cancerYeon Joo Kim
Research Institute and Hospital, National Cancer Center, Goyang, Korea
Acta Oncol 52:477-85. 2013..Hypofractionated radiotherapy potentially offers therapeutic gain for prostate cancer. We investigated the feasibility of hypofractionated proton therapy (PT)...
Association between the location of transposed ovary and ovarian function in patients with uterine cervical cancer treated with (postoperative or primary) pelvic radiotherapyJong Ha Hwang
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea
Fertil Steril 97:1387-93.e1-2. 2012..To evaluate the effectiveness of ovarian transposition procedures in preserving ovarian function in relation to the location of the transposed ovaries in patients who underwent surgery with or without pelvic radiotherapy...
Estimation of the secondary cancer risk induced by diagnostic imaging radiation during proton therapyHojin Jeong
Proton Therapy Center, National Cancer Center, Goyang, Republic of Korea
J Radiol Prot 31:477-87. 2011..These results showed that the additional SCR introduced by imaging radiation could be efficiently reduced by minimizing the imaging field size during image-guided procedures...
Tumor-associated carbonic anhydrases are linked to metastases in primary cervical cancerJoo Young Kim
Research Institute, National Cancer Center, Gyeonggi, Goyang, Korea
J Cancer Res Clin Oncol 132:302-8. 2006..We also examined whether CA9 expression can be an indicator of reoxygenation of tumor by measuring its mRNA expression during fractionated radiotherapy...
Diagnostic value of (18)F-FDG PET for evaluation of paraaortic nodal metastasis in patients with cervical carcinoma: a metaanalysisSokbom Kang
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea
J Nucl Med 51:360-7. 2010..We assessed the diagnostic performance of (18)F-FDG PET in detecting paraaortic lymph node (PALN) metastasis in patients with cervical cancer...
Role of positron emission tomography in pretreatment lymph node staging of uterine cervical cancer: a prospective surgicopathologic correlation studyJu Won Roh
Research Institute and Hospital, National Cancer Center, 809, Madu dong, Ilsan, Goyang, Gyeonggi, Korea
Eur J Cancer 41:2086-92. 2005....
A prospective observational study with dose volume parameters predicting rectosigmoidoscopic findings and late rectosigmoid bleeding in patients with uterine cervical cancer treated by definitive radiotherapyTae Hyun Kim
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, South Korea
Radiat Oncol 8:28. 2013..We assessed the value of dose-volumetric parameters predicting rectosigmoid mucosal changes (RMC) and late rectosigmoid complications (LRC)...
Human papillomavirus 16 E6 increases the radiosensitivity of p53-mutated cervical cancer cells, associated with up-regulation of aurora AHye Jin Shin
Research Institute and Hospital, National Cancer Center, Goyang, Korea
Int J Radiat Biol 86:769-79. 2010..To examine the effect of the human papillomavirus (HPV) type 16-E6 (HPV 'early' gene) oncoprotein on in vitro radiosensitivity of HPV-negative/p53 mutant C33a cervical cancer cells...
Craniospinal irradiation techniques: a dosimetric comparison of proton beams with standard and advanced photon radiotherapyMyonggeun Yoon
Proton Therapy Center, National Cancer Center, Goyang, Korea
Int J Radiat Oncol Biol Phys 81:637-46. 2011..To evaluate the dosimetric benefits of advanced radiotherapy techniques for craniospinal irradiation in cancer in children...
Stage-to-stage comparison of neoadjuvant chemotherapy versus adjuvant chemotherapy in pathological lymph node positive breast cancer patientsNam Kwon Lee
Proton Therapy Center, Research Institute and Hospital, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
Jpn J Clin Oncol 42:995-1001. 2012....
Intensity-modulated radiotherapy with a belly board for rectal cancerJoo Young Kim
Research Institute and Hospital, National Cancer Center, Goyang, South Korea
Int J Colorectal Dis 22:373-9. 2007..The aim of this study was to determine whether additional use of a belly board reduced the irradiated small bowel volume observed using IMRT alone in rectal cancer patients...
Brain metastasis in patients with uterine cervical cancerJong Ha Hwang
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea
J Obstet Gynaecol Res 39:287-91. 2013..The purpose of this study was to describe the features of patients with brain metastasis from cervical cancer...
Pelvic exenteration for recurrent cervical cancer: ten-year experience at National Cancer Center in KoreaHeon Jong Yoo
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea
J Gynecol Oncol 23:242-50. 2012..To evaluate survival and morbidity after pelvic exenteration (PE) for the curative management of recurrent cervical cancer...
Expression of carbonic anhydrase IX is associated with postoperative recurrence and poor prognosis in surgically treated oral squamous cell carcinomaSung Weon Choi
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi 410 350, Korea
Hum Pathol 39:1317-22. 2008..In conclusion, CA9 expression was a frequent and tumor-specific event in oral SCC. CA9 demonstrated significant associations with disease recurrence and poor clinical outcome and shows potential as a prognostic factor for oral SCC...
Tumor carbonic anhydrase 9 expression is associated with the presence of lymph node metastases in uterine cervical cancerSun Lee
Radiation Oncology, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang si, Gyeonggi Do, 411 769, Korea
Cancer Sci 98:329-33. 2007..Selective application of new treatment modalities based on CA9 expression to prevent LN metastases may improve overall treatment outcome in patients with uterine cervical cancer...
3D CT-based high-dose-rate brachytherapy for cervical cancer: clinical impact on late rectal bleeding and local controlHyun Cheol Kang
Research Institute and Hospital, National Cancer Center, Republic of Korea
Radiother Oncol 97:507-13. 2010..To identify the impact of 3D CT-based high-dose-rate intracavitary radiotherapy (ICR) on late rectal bleeding (LRB) and local control (LC) in patients with cervical cancer...
LY294002 inhibits interferon-gamma-stimulated inducible nitric oxide synthase expression in BV2 microglial cellsSo Young Hwang
Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea
Biochem Biophys Res Commun 318:691-7. 2004....
Effect of radiation scattering on dose uniformity in open and closed cell culture vesselsMyonggeun Yoon
Radiation Oncology, Proton Therapy Center, National Cancer Center, Ilsandong gu, Goyang, Korea
Int J Radiat Biol 83:561-6. 2007..In this study, we investigated X-ray dose inhomogeneity, caused by scattering, in typical culture vessels...
Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasionHye Jin Shin
Research Institute and Hospital, National Cancer Center, Goyang 410 769, Korea
J Cell Sci 124:1077-87. 2011..Our study shows an underlying mechanism of CA9-related enhanced metastatic potential of tumor cells...
Combined primary tumor and extracranial metastasis status as constituent factor of prognostic indices for predicting the overall survival in patients with brain metastasesYoung Hee Park
Research Institute and Hospital, National Cancer Center, Goyang, Korea
J Korean Med Sci 28:205-12. 2013....
Pathologic diagnosis and resection of suspicious thoracic metastases in patients with cervical cancer through thoracotomy or video-assisted thoracic surgeryMyong Cheol Lim
Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi Do, Korea
Gynecol Oncol 116:478-82. 2010..The purpose of this study was to clarify the role of resection for suspicious thoracic metastasis in cervical cancer patients with thoracotomy or video-assisted thoracic surgery (VATS)...
Allogeneic blood transfusion given before radiotherapy is associated with the poor clinical outcome in patients with cervical cancerMyong Cheol Lim
Research Institute and Hospital, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
Yonsei Med J 49:993-1003. 2008..To analyze the effect of allogeneic blood transfusion on clinical outcome in 119 patients with stage IIB cervical cancer who were treated with radiotherapy +/- chemotherapy...
Cyclooxygenase-2 up-regulates ataxia telangiectasia and Rad3 related through extracellular signal-regulated kinase activationYoung Mee Kim
Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Republic of Korea
Mol Cancer Res 7:1158-68. 2009..COX-2 stimulates ERK phosphorylation via PGE2. This COX-2-induced ERK activation seems to increase ATR expression and activity in endogenous COX-2-overexpressing cancer cells as well as in COX-2-overexpressing stable cell lines...
Retrospective analysis of treatment outcome of pediatric ependymomas in Korea: analysis of Korean multi-institutional dataYeon Joo Kim
Research Institute and Hospital, National Cancer Center, Goyang, South Korea
J Neurooncol 113:39-48. 2013..Postoperative RT was a strong prognostic factor for intracranial ependymomas. Our results suggest that early use of RT is an essential component of treatment, and should be considered in young children...
SMART (simultaneous modulated accelerated radiotherapy) for locally advanced nasopharyngeal carcinomasWoong Sub Koom
Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, South Korea
Head Neck 30:159-69. 2008..Concurrent chemoradiotherapy is commonly used for locally advanced nasopharyngeal carcinoma (NPC). We retrospectively analyzed the clinical outcomes of simultaneous modulated accelerated radiotherapy (SMART) with concurrent chemotherapy...
The clinical outcomes of proton beam radiation therapy for retinoblastomas that were resistant to chemotherapy and focal treatmentJi Woong Chang
Department of Ophthalmology, Inje University Ilsan Paik Hospital, Goyang, Korea
Korean J Ophthalmol 25:387-93. 2011..To evaluate the clinical results of proton beam radiation therapy (PBRT) for treatment of retinoblastoma...
Carbonic anhydrase 9 (CA9) expression in tumor cells enhances sensitivity to tirapazamineHye Jin Shin
Radiation Oncology, Research Institute and Hospital, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang si, Gyeonggi do 411 769, South Korea
J Cancer Res Clin Oncol 134:397-404. 2008....
Dose-volumetric parameters for predicting severe radiation pneumonitis after three-dimensional conformal radiation therapy for lung cancerTae Hyun Kim
Research Institute and Hospital, National Cancer Center, 809 Madu 1-dong, Ilsan-gu, Goyang, Gyeonggi 411-764, Korea
Radiology 235:208-15. 2005..05). In multivariate analysis, MLD was the only variable associated with severe RP. CONCLUSION: MLD is a useful indicator of risk for development of severe RP after 3D conformal radiation therapy in patients with lung cancer...
Is human papillomavirus genotype an influencing factor on radiotherapy outcome? Ambiguity caused by an association of HPV 18 genotype and adenocarcinoma histologyJoo Young Kim
Research Institute and Hospital, National Cancer Center, Goyang, Korea
J Gynecol Oncol 22:32-8. 2011..To evaluate whether human papillomavirus (HPV) genotype is associated with poor prognosis of uterine cervical cancer treated primarily with radiotherapy...
