Dong Ho Nahm

Summary

Country: Korea

Publications

  1. ncbi Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma
    Dong Ho Nahm
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    Am J Respir Crit Care Med 165:1536-9. 2002
  2. ncbi Identification of alpha-enolase as an autoantigen associated with severe asthma
    Dong Ho Nahm
    Department of Allergy and Rheumatology, Ajou University Hospital, Suwon 443 721, Korea
    J Allergy Clin Immunol 118:376-81. 2006
  3. pmc Treatment of severe atopic dermatitis with a combination of subcutaneous allergen immunotherapy and cyclosporin
    Dong Ho Nahm
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, 164 Worldcup ro, Yeongtong Gu, Suwon 443 721, Korea
    Yonsei Med J 53:158-63. 2012
  4. ncbi Increased levels of IgG to cytokeratin 19 in sera of patients with toluene diisocyanate-induced asthma
    Jung Hee Choi
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    Ann Allergy Asthma Immunol 93:293-8. 2004
  5. pmc Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 21:412-7. 2006
  6. pmc Changes of serum cytokines after the long term immunotherapy with Japanese hop pollen extracts
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 21:805-10. 2006
  7. pmc Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients
    Sun Sin Kim
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, San 5, Wonchondong, Paldalgu, Suwon 442 749, Korea
    J Korean Med Sci 18:42-7. 2003
  8. pmc Role of IgG, IgA, and IgE antibodies in nasal polyp tissue: their relationships with eosinophilic infiltration and degranulation
    Kyung Sik Suh
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 17:375-80. 2002
  9. pmc Cytokeratin autoantibodies: useful serologic markers for toluene diisocyanate-induced asthma
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Korea
    Yonsei Med J 47:773-81. 2006
  10. pmc Isotype and IgG subclass distribution of autoantibody response to alpha-enolase protein in adult patients with severe asthma
    Hye Ah Lee
    Department of Allergy and Rheumatology, Ajou University School of Medicine, San 5, Wonchon dong, Yeongtong Gu, Suwon 443 721, Korea
    Yonsei Med J 49:923-30. 2008

Collaborators

  • Hae Sim Park
  • Young Mok Lee
  • Choon Sik Park
  • Cheol Woo Kim
  • Jin-Woo Lee
  • Hyoung Ryoul Kim
  • J W Holloway
  • Young Ju Jang
  • Chang Hee Suh
  • ADAM WISNEWSKI
  • C A Redlich
  • Keehyun Park
  • Young Min Ye
  • Seung Hyun Kim
  • Jeong Hee Choi
  • Yoo Seob Shin
  • Soo Keol Lee
  • Joo Hee Kim
  • Myoung Eun Kim
  • Gil Soon Choi
  • Jin Young Kim
  • Eui Kyung Hwang
  • Sun Sin Kim
  • Jeong Eun Kim
  • Byul Kwon
  • Hye Ah Lee
  • Yu Jin Suh
  • Jin Sik Bae
  • Sang Ha Kim
  • Su Mi Cho
  • Mi Ae Kim
  • Jun Chul Park
  • Young Hee Nam
  • Hyun Jung Jin
  • Gyu Young Hur
  • Jung Hee Choi
  • Eun Jung Jang
  • Yoon Keun Kim
  • Hyunee Yim
  • Ho Joo Yoon
  • Jung Mi Oh
  • Hye Soo Yoo
  • Ki Suck Jung
  • Kyung Sik Suh
  • Jung Won Park
  • Joon Seong Park
  • Jing Nan Liu
  • Sang Min Lee
  • Joon Mo Sung
  • Sung Jin Choi
  • Bou Oung Lee
  • Jee Young Shin
  • Sang Ryeol Ryu
  • Chein Soo Hong
  • Hong Lei Yu
  • Hyung Doo Shin
  • Eun Ho Ha
  • Jae Hyun Cho
  • Young Suk Kim
  • Sung Wan Ahn
  • Hyun ee Lim
  • Jeung Hee Choi
  • Myung Hyun Lee
  • Kyung Up Min
  • Sang Heon Cho
  • You Young Kim

Detail Information

Publications38

  1. ncbi Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma
    Dong Ho Nahm
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    Am J Respir Crit Care Med 165:1536-9. 2002
    ..In this study, we identified cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma. Further studies are needed to determine the significance of autoimmunity in nonallergic asthma...
  2. ncbi Identification of alpha-enolase as an autoantigen associated with severe asthma
    Dong Ho Nahm
    Department of Allergy and Rheumatology, Ajou University Hospital, Suwon 443 721, Korea
    J Allergy Clin Immunol 118:376-81. 2006
    ..Approximately 5% to 10% of patients with asthma have severe disease that is not effectively controlled by typical therapies. The existence of an autoantigen associated with severe asthma has been previously reported...
  3. pmc Treatment of severe atopic dermatitis with a combination of subcutaneous allergen immunotherapy and cyclosporin
    Dong Ho Nahm
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, 164 Worldcup ro, Yeongtong Gu, Suwon 443 721, Korea
    Yonsei Med J 53:158-63. 2012
    ..Cyclosporin has been regarded as an effective medication for treatment of severe AD. In this study, we investigated a clinical usefulness of combined treatment with SCIT and cyclosporin in patients with severe AD...
  4. ncbi Increased levels of IgG to cytokeratin 19 in sera of patients with toluene diisocyanate-induced asthma
    Jung Hee Choi
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    Ann Allergy Asthma Immunol 93:293-8. 2004
    ..Inhaled isocyanate binds with cytokeratin (CK) of the epithelial cells, which could induce immune responses...
  5. pmc Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 21:412-7. 2006
    ..normal controls, (p=0.001 and p=0.003, respectively). Further studies are needed to explore the potential involvement of an autoantibody-mediated mechanism in the clinical manifestation of bronchial asthma...
  6. pmc Changes of serum cytokines after the long term immunotherapy with Japanese hop pollen extracts
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 21:805-10. 2006
    ..In conclusion, these findings suggested the favorable effect of long term immunotherapy with Hop J pollen extracts can be explained by lowered IgE affinity and generation of specific IgG4, which may be mediated by IL-10 and TGF-beta1...
  7. pmc Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients
    Sun Sin Kim
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, San 5, Wonchondong, Paldalgu, Suwon 442 749, Korea
    J Korean Med Sci 18:42-7. 2003
    ..NCA derived from mast cell may contribute to the development of early asthmatic response induced by L-ASA inhalation. There may be a possible involvement of NCA derived from mononuclear cells during late asthmatic response...
  8. pmc Role of IgG, IgA, and IgE antibodies in nasal polyp tissue: their relationships with eosinophilic infiltration and degranulation
    Kyung Sik Suh
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 17:375-80. 2002
    ..These results suggest that DP-sIgE was detectable in NP tissue from weakly atopic subjects as well as highly atopic subjects. IgG and sIgE may have potential roles in eosinophil degranulation in NP tissue...
  9. pmc Cytokeratin autoantibodies: useful serologic markers for toluene diisocyanate-induced asthma
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Korea
    Yonsei Med J 47:773-81. 2006
    ..These results suggest that autoantibodies to CK18 and CK19 can be used as serologic markers for identifying patients with TDI-induced asthma among exposed workers...
  10. pmc Isotype and IgG subclass distribution of autoantibody response to alpha-enolase protein in adult patients with severe asthma
    Hye Ah Lee
    Department of Allergy and Rheumatology, Ajou University School of Medicine, San 5, Wonchon dong, Yeongtong Gu, Suwon 443 721, Korea
    Yonsei Med J 49:923-30. 2008
    ....
  11. pmc Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population
    Seung Hyun Kim
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 20:926-31. 2005
    ..These results suggested that ALOX5 has a differing contribution in two major clinical pathogenesis related to ASA-sensitivity...
  12. pmc Antigen-binding characteristics of circulating IgG autoantibodies to cytokeratin 18 protein in patients with nonallergic asthma
    Hyunee Yim
    Department of Allergy and Rheumatology, Ajou University Hospital, Yeongtong Gu, Suwon, Korea
    J Korean Med Sci 21:652-5. 2006
    ....
  13. ncbi Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma
    Young Min Ye
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Allergy Clin Immunol 118:885-91. 2006
    ..Structural elucidation of TDI-albumin conjugates is crucial to understanding the human immune response to TDI exposure...
  14. pmc Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma
    Jung Mi Oh
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    Korean J Intern Med 20:232-6. 2005
    ..Therefore we investigated whether this polymorphism may be associated with the development of aspirin-intolerant asthma (AIA)...
  15. ncbi Alpha amylase is a major allergenic component in occupational asthma patients caused by porcine pancreatic extract
    Hae Sim Park
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    J Asthma 39:511-6. 2002
    ..Thesefindings suggest that inhalation of PPE powder can induce IgE-mediated bronchoconstriction in exposed nurses. Alpha-amylase is a major allergenic component within PPE...
  16. ncbi Serum cytokine profiles in patients with adult onset Still's disease
    Jeong Hee Choi
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Paldalgu Woncheondong San 5, Suwon, Korea 442 749
    J Rheumatol 30:2422-7. 2003
    ..To evaluate the pathogenesis and disease activity of AOSD, we measured serial serum concentrations of several cytokines in patients with active and inactive disease...
  17. ncbi Localization of inducible nitric oxide synthase and endothelial constitutive nitric oxide synthase in airway mucosa of toluene diisocyanate-induced asthma
    Soo Keol Lee
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Paldalgu Wonchondong San 5, Suwon 442 721, Korea
    Allergy Asthma Proc 24:275-80. 2003
    ..05, respectively). In conclusion, i-NOS and c-NOS expressions were noted in EP, SM, VE, and MG in airway mucosa of TDI-induced asthma patients, which may contribute to airway inflammation...
  18. pmc Exposure to toluene diisocyanate (TDI) induces IL-8 production from bronchial epithelial cells: effect of pro-inflammatory cytokines
    Young Mok Lee
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 18:809-12. 2003
    ..IL-1beta released from PBMC of TDI-induced asthma patients may be one of the pro-inflammatory cytokines to enhance IL-8 production...
  19. doi Increased IgG antibody-induced cytotoxicity against airway epithelial cells in patients with nonallergic asthma
    Byul Kwon
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, South Korea
    J Clin Immunol 29:517-23. 2009
    ..IgG autoantibodies to airway epithelial cell proteins have been detected in patients with nonallergic asthma...
  20. pmc Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients
    Jeong Hee Choi
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 19:359-63. 2004
    ..05). These results suggest that VEGF may play a minor role in immediate bronchoconstriction after TDI-BPT. In chronic TDI-asthma, VEGF may be involved to 2 yr after the diagnosis and the contribution may decrease after then...
  21. pmc Clinical Features and the Diagnostic Value of Component Allergen-Specific IgE in Hymenoptera Venom Allergy
    Yoo Seob Shin
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    Allergy Asthma Immunol Res 4:284-9. 2012
    ..We evaluated the diagnostic value of serum-specific IgE detection of hymenoptera venom component allergens and documented changes in allergen-specific IgE after immunotherapy...
  22. pmc Eosinophil inflammation of nasal polyp tissue: relationships with matrix metalloproteinases, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1
    Young Mok Lee
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 18:97-102. 2003
    ..Close correlations were noted between TGF-beta1, and MMP-9 and MMP-2, but not with TIMP-1. MMP-2, MMP-9, and TGF-beta1 may contribute to eosinophil and mast cell migrations into nasal polyp tissue...
  23. pmc Immunoglobulin G subclass deficiency is the major phenotype of primary immunodeficiency in a Korean adult cohort
    Joo Hee Kim
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 25:824-8. 2010
    ..IgG and IgG subclass deficiency should be considered in adult patients presenting with recurrent upper and lower respiratory infections, particularly in those with respiratory allergies or autoimmune diseases...
  24. pmc Evaluating the allergic risk of genetically modified soybean
    Sang Ha Kim
    Department of Allergy, Ajou University School of Medicnie, Suwon, Korea
    Yonsei Med J 47:505-12. 2006
    ..In addition, based on both in vivo and in vitro methods, the allergenicity of wild type and GM soybean extracts was identical...
  25. pmc Safety of accelerated schedules of subcutaneous allergen immunotherapy with house dust mite extract in patients with atopic dermatitis
    Myoung Eun Kim
    Department of Allergy and Clinical Immunology, Ajou University Hospital, Suwon, Korea
    J Korean Med Sci 26:1159-64. 2011
    ..2%) with AD and BA who showed systemic reactions during rush or ultra-rush immunotherapy. In conclusion, ASAI was safe and well tolerated in patients with AD. ASAI can be a useful therapeutic option for AD...
  26. doi A computerized asthma-specific quality of life: a novel tool for reflecting asthma control and predicting exacerbation
    Mi Ae Kim
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Republic of Korea
    Int Arch Allergy Immunol 163:36-42. 2014
    ..045, p = 0.019, respectively). Conclusion: The cA-QOL is a valid tool for reflecting current asthma control status and for assessment to predict the future risk of asthma exacerbation in adult asthmatics. © 2013 S. Karger AG, Basel. ..
  27. ncbi Significant association of FcepsilonRIalpha promoter polymorphisms with aspirin-intolerant chronic urticaria
    Jin Sik Bae
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    J Allergy Clin Immunol 119:449-56. 2007
    ..Although the mechanism that underlies aspirin hypersensitivity is not completely understood, an IgE-mediated response was reported for a patient with aspirin-intolerant chronic urticaria (AICU)...
  28. doi Clinical efficacy of autologous plasma therapy for atopic dermatitis
    Su Mi Cho
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Republic of Korea
    Dermatology 228:71-7. 2014
    ..05). Conclusion: This result suggests that the blood component mediating the therapeutic efficacy of ABT in patients with AD might be present in the high-molecular-weight plasma protein fraction. © 2013 S. Karger AG, Basel. ..
  29. pmc The predictors of poorly controlled asthma in elderly
    Eui Kyung Hwang
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    Allergy Asthma Immunol Res 4:270-6. 2012
    ..To evaluate asthma control in elderly individuals and identify the factors that predict poor control...
  30. pmc Acute urticaria caused by the injection of goat-derived hyaluronidase
    Joo Hee Kim
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    Allergy Asthma Immunol Res 1:48-50. 2009
    ..This is the first case of an IgE-medicated allergic reaction to goat (Naemorhedus goral raddenus) hyaluronidase, demonstrated by skin testing and a specific IgE and immunoblot assay...
  31. ncbi Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma
    Hae Sim Park
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Paldalgu, Wonchondong San 5, Suwon, Korea
    Korean J Intern Med 17:249-51. 2002
    ..A recent investigation suggested a role of specific IgG (sIgG) in the development of TDI asthma...
  32. pmc Rheumatoid factor is a marker of disease severity in Korean rheumatoid arthritis
    Yoo Seob Shin
    Department of Allergy Rheumatology, Ajou University School of Medicine, San 5 Woncheon dong, Youngtong Gu, Suwon 442 721, Korea
    Yonsei Med J 46:464-70. 2005
    ..05), especially triple DMARD combination. These results suggest that disease activity is more severe in the seropositive than the seronegative group, and more aggressive treatments are needed in the seropositive group...
  33. doi Double-filtration plasmapheresis for the treatment of patients with recalcitrant atopic dermatitis
    Jin Young Kim
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea
    Ther Apher Dial 17:631-7. 2013
    ..7) (P > 0.05). DFPP resulted in significant clinical improvements in patients with recalcitrant AD. Further studies are needed to evaluate the long-term clinical usefulness of DFPP in the treatment of patients with recalcitrant AD...
  34. doi Treatment of atopic dermatitis with a combination of allergen-specific immunotherapy and a histamine-immunoglobulin complex
    Dong Ho Nahm
    Department of Allergy and Rheumatology, Ajou University Hospital, Suwon, Korea
    Int Arch Allergy Immunol 146:235-40. 2008
    ..We performed a pilot study to evaluate the clinical usefulness of combined treatment with allergen-specific immunotherapy and a histamine-immunoglobulin complex in patients with atopic dermatitis...
  35. doi Mouse monoclonal autoantibodies penetrate mouse macrophage cells and stimulate NF-kappaB activation and TNF-alpha release
    Eun Jung Jang
    Institute for Medical Science and Brain Korea 21 Program, Ajou University School of Medicine, Suwon 443 721, Republic of Korea
    Immunol Lett 124:70-6. 2009
    ....
  36. ncbi Heterogeneity of IgE response to cefteram pivoxil was noted in 2 patients with cefteram-induced occupational asthma
    Yu Jin Suh
    J Allergy Clin Immunol 112:209-10. 2003
  37. ncbi Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population
    Jeong Hee Choi
    Department of Pulmonology and Allergies, Bundang Jesaeng General Hospital, Seongnam, Korea
    Tohoku J Exp Med 208:49-56. 2006
    ..05). These results indicate that there is no association between these two promoter polymorphisms of LTC4S and the phenotype of AIA in a Korean population...
  38. ncbi Two-spotted spider mite allergy: immunoglobulin E sensitization and characterization of allergenic components
    Yoon Keun Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Ann Allergy Asthma Immunol 89:517-22. 2002
    ..We determined the sensitization rate to TSM. We also identified immunoglobulin (Ig)E-binding components and evaluated their relationship with house-dust mite (HDM) allergens...