Dong Jae Baek
Affiliation: Mokpo National University
Shrestha J, Ki S, Shin S, Kim S, Lee J, Jun H, et al
. Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation. Molecules. 2018;23: pubmed publisher
..In the docking study of compound 7 and PP2A, the amide chain of compound 7 showed an interaction with Asn61 that was different from FTY720, which is expected to affect the activity of the compound. ..
Lee D, Kim D, Lee S, Kim T, Kim J, Kim S, et al
. Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches. Molecules. 2015;20:19984-20013 pubmed publisher
..The target secondary and tertiary 1,2,3-triazoloamide derivatives were obtained with three-diversity points in excellent overall yields and purities using the reported solid- and solution-phase synthetic routes, respectively. ..
Bae G, Park E, Baek D, Jun H, Oh Y. Liquiritigenin prevents palmitate-induced beta-cell apoptosis via estrogen receptor-mediated AKT activation. Biomed Pharmacother. 2018;101:348-354 pubmed publisher
..We conclude that estrogen receptor-mediated AKT phosphorylation is one of the mechanisms contributing to the anti-apoptotic effect of LQ. ..
Park E, Lee T, Oh Y, Lee J, Shrestha J, Hong S, et al
. Synthesis of dansyl labeled sphingosine kinase 1 inhibitor. Chem Phys Lipids. 2018;215:29-33 pubmed publisher
..A docking study of SK1 and SK1 inhibitory activity confirmed the structural similarity between the synthetic dansyl-PF-543 and PF-543. We also provide fluorescence spectra of dansyl-PF-543. ..