Yun Jung Lee

Summary

Country: Korea

Publications

  1. pmc Arctium lappa ameliorates endothelial dysfunction in rats fed with high fat/cholesterol diets
    Yun Jung Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk, Republic of Korea
    BMC Complement Altern Med 12:116. 2012
  2. ncbi request reprint Anti-Inflammatory effect of Buddleja officinalis on vascular inflammation in human umbilical vein endothelial cells
    Yun Jung Lee
    Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Am J Chin Med 38:585-98. 2010
  3. doi request reprint Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes
    Sun Mi Hwang
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Republic of Korea
    Am J Chin Med 40:937-51. 2012
  4. doi request reprint Gardenia jasminoides inhibits tumor necrosis factor-alpha-induced vascular inflammation in endothelial cells
    Sun Mi Hwang
    Professional Graduate School of Oriental Medicine, Wonkwang University, Chonbuk, Republic of Korea
    Phytother Res 24:S214-9. 2010
  5. doi request reprint Cynanchum wilfordii ameliorates hypertension and endothelial dysfunction in rats fed with high fat/cholesterol diets
    Deok Ho Choi
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk, Republic of Korea
    Immunopharmacol Immunotoxicol 34:4-11. 2012
  6. ncbi request reprint Effect of caffeic acid on tumor necrosis factor-alpha-induced vascular inflammation in human umbilical vein endothelial cells
    Mi Kyoung Moon
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Biol Pharm Bull 32:1371-7. 2009
  7. doi request reprint Effect of Benincasa hispida Cogniaux on high glucose-induced vascular inflammation of human umbilical vein endothelial cells
    Mi Kyoung Moon
    Professional Graduate School of Oriental Medicine Wonkwang University, Iksan, Jeonbuk, 570 749, Republic of Korea
    Vascul Pharmacol 50:116-22. 2009
  8. doi request reprint Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria
    Hye Yoom Kim
    Hanbang Body fluid Research Center and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, Republic of Korea
    Life Sci 94:145-50. 2014
  9. doi request reprint Inhibitory effect of Thuja orientalis on TNF-α-induced vascular inflammation
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Hanbang Body fluid Research Center, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    Phytother Res 24:1489-95. 2010
  10. ncbi request reprint Anti-inflammatory effect of Gastrodia elata rhizome in human umbilical vein endothelial cells
    Sun Mi Hwang
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk, 570 749, Republic of Korea
    Am J Chin Med 37:395-406. 2009

Collaborators

  • Jin Sook Kim
  • Xiang Li
  • Kyung Woo Cho
  • Bin Li
  • Song Nan Jin
  • Dae Gill Kang
  • Ho Sub Lee
  • Jung Joo Yoon
  • So Min Lee
  • Sun Mi Hwang
  • An Sook Lee
  • Deok Ho Choi
  • Mi Kyoung Moon
  • Hao Zhen Cui
  • Hye Yoom Kim
  • Eun Ju Kim
  • Hyun Cheol Oh
  • Li Hua Cao
  • Hye Ran Choi
  • Hyeok Lee
  • You Mee Ahn
  • Ying Lan Cui
  • Youn Chul Kim

Detail Information

Publications33

  1. pmc Arctium lappa ameliorates endothelial dysfunction in rats fed with high fat/cholesterol diets
    Yun Jung Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk, Republic of Korea
    BMC Complement Altern Med 12:116. 2012
    ..This study was performed to test the effect of ethanol extract of Arctium lappa L. (EAL) seeds on vascular reactivity and inflammatory factors in rats fed a high fat/cholesterol diet (HFCD)...
  2. ncbi request reprint Anti-Inflammatory effect of Buddleja officinalis on vascular inflammation in human umbilical vein endothelial cells
    Yun Jung Lee
    Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Am J Chin Med 38:585-98. 2010
    ....
  3. doi request reprint Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes
    Sun Mi Hwang
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Republic of Korea
    Am J Chin Med 40:937-51. 2012
    ..Taken together, APV suppressed hyperglycemia and diabetic vascular dysfunction in HFHC diet-db/db mice. The present data suggest that Prunella vulgaris may prevent development of diabetic atherosclerosis...
  4. doi request reprint Gardenia jasminoides inhibits tumor necrosis factor-alpha-induced vascular inflammation in endothelial cells
    Sun Mi Hwang
    Professional Graduate School of Oriental Medicine, Wonkwang University, Chonbuk, Republic of Korea
    Phytother Res 24:S214-9. 2010
    ....
  5. doi request reprint Cynanchum wilfordii ameliorates hypertension and endothelial dysfunction in rats fed with high fat/cholesterol diets
    Deok Ho Choi
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk, Republic of Korea
    Immunopharmacol Immunotoxicol 34:4-11. 2012
    ....
  6. ncbi request reprint Effect of caffeic acid on tumor necrosis factor-alpha-induced vascular inflammation in human umbilical vein endothelial cells
    Mi Kyoung Moon
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Biol Pharm Bull 32:1371-7. 2009
    ..CA reduced TNF-alpha-induced endothelial adhesiveness to HUVECs by inhibiting transcription factor activation, and CAMs expression suggesting its potential role in atherosclerosis diseases...
  7. doi request reprint Effect of Benincasa hispida Cogniaux on high glucose-induced vascular inflammation of human umbilical vein endothelial cells
    Mi Kyoung Moon
    Professional Graduate School of Oriental Medicine Wonkwang University, Iksan, Jeonbuk, 570 749, Republic of Korea
    Vascul Pharmacol 50:116-22. 2009
    ..ABH also reduced NF-kB promoter activity. These results suggest that ABH reduces high glucose-induced CAMs activation by inhibiting monocyte adhesion, ROS, and NF-kappaB in HUVECs...
  8. doi request reprint Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria
    Hye Yoom Kim
    Hanbang Body fluid Research Center and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, Republic of Korea
    Life Sci 94:145-50. 2014
    ..Ursolic acid has recently been reported to increase both atrial natriuretic peptide (ANP) secretion and mechanical dynamics in rabbit atria...
  9. doi request reprint Inhibitory effect of Thuja orientalis on TNF-α-induced vascular inflammation
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Hanbang Body fluid Research Center, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    Phytother Res 24:1489-95. 2010
    ..Overall, the present data suggest that ATO can suppress TNF-α-induced vascular inflammatory processes, possibly via inhibition of ROS and NF-κB activation, in HUVEC...
  10. ncbi request reprint Anti-inflammatory effect of Gastrodia elata rhizome in human umbilical vein endothelial cells
    Sun Mi Hwang
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk, 570 749, Republic of Korea
    Am J Chin Med 37:395-406. 2009
    ..In conclusion, the present data suggest that EGE could suppress TNF-alpha-induced vascular inflammatory process via inhibition of oxidative stress and NF-kappaB activation in HUVEC...
  11. doi request reprint Buddleja officinalis inhibits high glucose-induced matrix metalloproteinase activity in human umbilical vein endothelial cells
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk, 570 749, Republic of Korea
    Phytother Res 22:1655-9. 2008
    ..These results provide new insights into the pathophysiological mechanisms for anti-inflammatory properties of ABO in vascular diseases associated with diabetes mellitus...
  12. doi request reprint Buddleja officinalis suppresses high glucose-induced vascular smooth muscle cell proliferation: role of mitogen-activated protein kinases, nuclear factor-kappaB and matrix metalloproteinases
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    Exp Biol Med (Maywood) 235:247-55. 2010
    ..Taken together, the present data suggest that EBO could suppress high glucose-induced atherosclerotic processes through inhibition of p38, JNK, NF-kappaB and MMP signal pathways in HASMC...
  13. doi request reprint Inhibitory effect of Zanthoxylum schinifolium on vascular smooth muscle proliferation
    Yun Jung Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Republic of Korea
    Immunopharmacol Immunotoxicol 34:354-61. 2012
    ....
  14. pmc Improved endothelial dysfunction by Cynanchum wilfordii in apolipoprotein E(-/-) mice fed a high fat/cholesterol diet
    Deok Ho Choi
    Hanbang Body fluid Research Center, Wonkwang University, Iksan, Jeonbuk, Korea
    J Med Food 15:169-79. 2012
    ....
  15. doi request reprint Betulinic acid inhibits high glucose-induced vascular smooth muscle cells proliferation and migration
    Jung Joo Yoon
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    J Cell Biochem 111:1501-11. 2010
    ....
  16. doi request reprint Poria cocos inhibits high glucose-induced proliferation of rat mesangial cells
    Jung Joo Yoon
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Jeonbuk 570 749, Republic of Korea
    Am J Chin Med 41:71-83. 2013
    ..Taken together, these results suggest that P. cocos may be a potent regulator of HG-induced proliferation...
  17. ncbi request reprint An aqueous extract of Portulaca oleracea ameliorates diabetic nephropathy through suppression of renal fibrosis and inflammation in diabetic db/db mice
    An Sook Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Jeonbuk, Republic of Korea
    Am J Chin Med 40:495-510. 2012
    ..Taken together, these findings suggest that AP attenuates diabetic nephropathy through inhibition of renal fibrosis and inflammation in db/db mice...
  18. doi request reprint Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells
    So Min Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    Inflammation 35:584-93. 2012
    ..In conclusion, vitexicarpin significantly reduced vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells...
  19. doi request reprint Effect of Zanthoxylum schinifolium on TNF-alpha-induced vascular inflammation in human umbilical vein endothelial cells
    Li Hua Cao
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, 570 749, Republic of Korea
    Vascul Pharmacol 50:200-7. 2009
    ..Taken together, these results demonstrate that EZS suppresses vascular inflammatory process, which may be closely related to the inhibition of ROS, JNK, p38 MAPK and NF-kappaB activation in HUVEC...
  20. doi request reprint Protective role of betulinic acid on TNF-alpha-induced cell adhesion molecules in vascular endothelial cells
    Jung Joo Yoon
    Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk 570 749, Republic of Korea
    Biochem Biophys Res Commun 391:96-101. 2010
    ..In conclusion, these results suggested a vascular protective role of BA via inhibition of ROS and NF-kappaB activation in HUVEC...
  21. doi request reprint Bakuchicin induces vascular relaxation via endothelium-dependent NO-cGMP signaling
    Xiang Li
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Phytother Res 25:1574-8. 2011
    ..These results suggested that bakuchicin-induced vasodilatation is closely associated with the endothelium-dependent nitric oxide (NO)/cGMP signaling pathway, with the possible involvement of L-type Ca(2+) channels...
  22. doi request reprint Effect of Poria cocos on hypertonic stress-induced water channel expression and apoptosis in renal collecting duct cells
    So Min Lee
    Department of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan 570 749, Republic of Korea Hanbang Body Fluid Research Center, Wonkwang University, Iksan 570 749, Republic of Korea
    J Ethnopharmacol 141:368-76. 2012
    ..The dried sclerotia of Poria cocos Wolf has been known to have a diuretic effect and used for the treatment of chronic edema and nephrosis...
  23. ncbi request reprint Hypotensive, hypolipidemic, and vascular protective effects of Morus alba L. in rats fed an atherogenic diet
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Jeonbuk, 570 749, Republic of Korea
    Am J Chin Med 39:39-52. 2011
    ..could improve an atherogenic diet-induced hypertension, hyperlipidemia, and vascular dysfunction through inhibition of cell adhesion molecules expression and induction of vascular relaxation...
  24. doi request reprint Effect of Gastrodia elata on tumor necrosis factor-alpha-induced matrix metalloproteinase activity in endothelial cells
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    J Nat Med 63:463-7. 2009
    ..These results provide new insights into the pathophysiological mechanisms for the anti-atherosclerotic properties of EGE in vascular diseases...
  25. pmc Ethanol extract of Lycopus lucidus elicits positive inotropic effect via activation of Ca2+ entry and Ca2+ release in beating rabbit atria
    Hao Zhen Cui
    Professional Graduate School of Oriental Medicine and College of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, Korea
    J Med Food 16:633-40. 2013
    ..The results suggest that ELT exerts a positive inotropic effect via activation of Ca(2+) entry through L-type Ca(2+) channel and Ca(2+) release from the SR in beating rabbit atria...
  26. pmc Prunella vulgaris Suppresses HG-Induced Vascular Inflammation via Nrf2/HO-1/eNOS Activation
    Sun Mi Hwang
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk 570 749, Korea E Mails S M H Y J L
    Int J Mol Sci 13:1258-68. 2012
    ....
  27. doi request reprint Sauchinone from Saururus chinensis protects vascular inflammation by heme oxygenase-1 induction in human umbilical vein endothelial cells
    Bin Li
    Hanbang Body fluid Research Center, Wonkwang University, Shinyong Dong, Iksan Jeonbuk, 570 749, Republic of Korea
    Phytomedicine 21:101-8. 2014
    ..These findings suggest that sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of sauchinone in HUVEC. ..
  28. pmc Portulaca oleracea Ameliorates Diabetic Vascular Inflammation and Endothelial Dysfunction in db/db Mice
    An Sook Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk 570 749, Republic of Korea
    Evid Based Complement Alternat Med 2012:741824. 2012
    ..Taken together, AP suppresses hyperglycemia and diabetic vascular inflammation, and prevents the development of diabetic endothelial dysfunction for the development of diabetes and its vascular complications...
  29. pmc Effect of Atractylodes macrocephala on Hypertonic Stress-Induced Water Channel Protein Expression in Renal Collecting Duct Cells
    Yong Pyo Lee
    Department of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan 570 749, Republic of Korea Hanbang Body Fluid Research Center, Wonkwang University, Iksan 570 749, Republic of Korea
    Evid Based Complement Alternat Med 2012:650809. 2012
    ..These results suggest that the AAM has a diuretic effect by suppressing water reabsorption via the downregulation of the TonEBP-AQP2 signaling pathway...
  30. doi request reprint Effect of Buddleja officinalis on high-glucose-induced vascular inflammation in human umbilical vein endothelial cells
    Yun Jung Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, 570 749, Republic of Korea
    Exp Biol Med (Maywood) 233:694-700. 2008
    ..The present data suggest that ABO could suppress high-glucose-induced vascular inflammatory processes, and ABO may be closely related with the inhibition of ROS and NF-kappaB activation in HUVEC...
  31. doi request reprint Renoprotective effect of Alpiniae oxyphyllae Fructus on ischemia/reperfusion-induced acute renal failure
    Eun Ju Kim
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, South Korea
    Arch Pharm Res 36:1004-12. 2013
    ..Taken together, the present study suggested that A. oxyphyllae ameliorates the urine concentration and renal functions in ischemia/reperfusion-induced ARF, through the restoring of AQP-2, 3 and Na,K-ATPase...
  32. pmc Anti-TNF-α Activity of Portulaca oleracea in Vascular Endothelial Cells
    An Sook Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Shinyong Dong, Iksan, Jeonbuk, 570 749, Korea E Mails A S L Y J L
    Int J Mol Sci 13:5628-44. 2012
    ..These results suggested that AP might have a potential therapeutic effect by inhibiting the vascular inflammation process in vascular diseases such as atherosclerosis...
  33. pmc Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle
    Xiang Li
    Professional Graduate School of Oriental Medicine and College of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, Republic of Korea
    Evid Based Complement Alternat Med 2012:148929. 2012
    ..Conclusion. Taken together, these results suggest that ESB relaxed rabbit cavernous smooth muscle via the NO/cGMP system and Ca(2+)-sensitive K(+) channels in the corpus cavernosum...