Genomes and Genes


Heon Jin Lee


Affiliation: Kyungpook National University
Country: Korea


  1. Kim J, Kang S, Oh S, Lee H, Lee I, Hwang J, et al. NGFI-A Binding Protein 2 Promotes EGF-Dependent HNSCC Cell Invasion. Cancers (Basel). 2019;11: pubmed publisher
    ..These results provide insight into the paradoxical roles of EGF-EGR1 in cancer progression. ..
  2. Choi S, Oh S, Kang S, Kang S, Kim J, Lee H, et al. NAB 2-Expressing Cancer-Associated Fibroblast Promotes HNSCC Progression. Cancers (Basel). 2019;11: pubmed publisher
    ..These data suggest that NAB2-overexpressing CAFs promotes HNSCC progression and is a potential therapeutic target for preventing HNSCC metastasis. ..
  3. Lee H. Microbe-Host Communication by Small RNAs in Extracellular Vesicles: Vehicles for Transkingdom RNA Transportation. Int J Mol Sci. 2019;20: pubmed publisher
    ..Thus, this review discussed the results of recent studies that have examined the ways in which EVs and sRNAs mediate 'microbe⁻host' and 'host⁻microbe' interspecies communication. ..
  4. Kang S, Choi J, Hong S, Lee H. Up-regulation of microRNA* strands by their target transcripts. Int J Mol Sci. 2013;14:13231-40 pubmed publisher
    ..miR-7b* levels were found to significantly increase after transfection of the artificial target. We postulate that the abundance of target transcripts drives miRNA arm selection. ..
  5. Choi S, Han E, Hong S, Kwon T, Lee Y, Lee H. Regulating Osteogenic Differentiation by Suppression of Exosomal microRNAs. Tissue Eng Part A. 2018;: pubmed publisher
    ..Genetically modified exosomes may thus serve as highly effective biomaterials for developmental control, including osteogenesis regulation. ..
  6. Lee H, Hong S. Analysis of microRNA-size, small RNAs in Streptococcus mutans by deep sequencing. FEMS Microbiol Lett. 2012;326:131-6 pubmed publisher
    ..mutans, which is one of the principle causative agents of dental caries, has to be elucidated. ..
  7. Kim J, Kang H, Lee Y, Lee H, Yun J, Shin J, et al. EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer. Cancer Lett. 2014;349:35-44 pubmed publisher
    ..These data showed a critical role of EGR1-PTEN signaling pathway in the EMT of colon cancer, as well as metastasis. ..
  8. Choi J, Kwon T, Hong S, Lee H. Isolation and Characterization of a microRNA-size Secretable Small RNA in Streptococcus sanguinis. Cell Biochem Biophys. 2018;76:293-301 pubmed publisher
    ..We furthermore observed small RNAs secreted via bacterial membrane vesicles. Although their precise function remains unclear, secretable small RNAs may represent an entirely new area of study in bacterial genetics. ..
  9. Kim J, Lee H, Hong S. Inhibition of streptococcal biofilm by hydrogen water. J Dent. 2017;58:34-39 pubmed publisher
    ..Our data suggest that oral rinse with H-water would be helpful in treating dental biofilm-dependent diseases with ease and efficiency. ..