Tae Hwan Kwon

Summary

Affiliation: Kyungpook National University
Country: Korea

Publications

  1. pmc Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, South Korea
    PLoS ONE 6:e28492. 2011
  2. pmc Vasopressin V2R-targeting peptide carrier mediates siRNA delivery into collecting duct cells
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    PLoS ONE 7:e40010. 2012
  3. pmc Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Korea
    Electrolyte Blood Press 8:59-65. 2010
  4. pmc Ubiquitination of aquaporin-2 in the kidney
    Yu Jung Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Korea
    Electrolyte Blood Press 7:1-4. 2009
  5. pmc Angiotensin II AT1 receptor blockade changes expression of renal sodium transporters in rats with chronic renal failure
    Eun Jung Kim
    Department of Physiology, School of Medicine, Dongguk University, Kyungju, Korea
    J Korean Med Sci 20:248-55. 2005
  6. ncbi request reprint Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with alpha3beta1 integrin
    Sun Woo Park
    Cell and Matrix Biology National Research Laboratory, Department of Biochemistry, School of Medicine, Kyungpook National University, Jung Gu, Daegu, Korea
    Exp Mol Med 36:211-9. 2004
  7. doi request reprint Aquaporin 3 expression is up-regulated by TGF-β1 in rat peritoneal mesothelial cells and plays a role in wound healing
    Hye Myung Ryu
    Division of Nephrology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, South Korea
    Am J Pathol 181:2047-57. 2012
  8. doi request reprint Patterns of gene and metabolite define the effects of extracellular osmolality on kidney collecting duct
    Hyo jung Choi
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    J Proteome Res 11:3816-28. 2012
  9. doi request reprint Application of phage display for ligand peptidomics to identify peptide ligands binding to AQP2-expressing membrane fractions
    Byung Heon Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, South Korea
    Methods Mol Biol 1023:181-9. 2013
  10. ncbi request reprint Expression of TGF-beta-induced matrix protein betaig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose
    Suk Hee Lee
    Cell and Matrix Biology, National Research Laboratory, Kyungpook National University, Taegu, Korea
    Kidney Int 64:1012-21. 2003

Collaborators

Detail Information

Publications28

  1. pmc Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, South Korea
    PLoS ONE 6:e28492. 2011
    ..In conclusion, AQP5 overexpression is likely to play a role in cell growth and metastasis of human breast cancer and could be a novel target for anti-breast cancer treatment...
  2. pmc Vasopressin V2R-targeting peptide carrier mediates siRNA delivery into collecting duct cells
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    PLoS ONE 7:e40010. 2012
    ..The methods could be potentially used in vivo to regulate abnormal expression of proteins associated with disease conditions in the V2R-expressing kidney cells...
  3. pmc Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160
    Hyun Jun Jung
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Korea
    Electrolyte Blood Press 8:59-65. 2010
    ..Thus, the results suggest that PI3K/Akt pathways could play a role in AQP2 trafficking via the AS160 protein...
  4. pmc Ubiquitination of aquaporin-2 in the kidney
    Yu Jung Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Korea
    Electrolyte Blood Press 7:1-4. 2009
    ..This minireview will discuss the ubiquitination of AQP2 and identification of potential E3 Ub-protein ligases for 1-deamino-8-D-arginine vasopressin (dDAVP)-dependent AQP2 regulation...
  5. pmc Angiotensin II AT1 receptor blockade changes expression of renal sodium transporters in rats with chronic renal failure
    Eun Jung Kim
    Department of Physiology, School of Medicine, Dongguk University, Kyungju, Korea
    J Korean Med Sci 20:248-55. 2005
    ....
  6. ncbi request reprint Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with alpha3beta1 integrin
    Sun Woo Park
    Cell and Matrix Biology National Research Laboratory, Department of Biochemistry, School of Medicine, Kyungpook National University, Jung Gu, Daegu, Korea
    Exp Mol Med 36:211-9. 2004
    ....
  7. doi request reprint Aquaporin 3 expression is up-regulated by TGF-β1 in rat peritoneal mesothelial cells and plays a role in wound healing
    Hye Myung Ryu
    Division of Nephrology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, South Korea
    Am J Pathol 181:2047-57. 2012
    ..These findings provide evidence of a novel role for AQP3 in peritoneal fibrosis and wound healing. The effect of TGF-β1 on AQP3 expression in HPMCs is mediated, at least in part, by ERK and p38 signaling...
  8. doi request reprint Patterns of gene and metabolite define the effects of extracellular osmolality on kidney collecting duct
    Hyo jung Choi
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    J Proteome Res 11:3816-28. 2012
    ....
  9. doi request reprint Application of phage display for ligand peptidomics to identify peptide ligands binding to AQP2-expressing membrane fractions
    Byung Heon Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, South Korea
    Methods Mol Biol 1023:181-9. 2013
    ..This chapter describes the procedures for phage display selection of peptide ligands that selectively bind to aquaporin-2-expressing membrane fractions of rat kidney...
  10. ncbi request reprint Expression of TGF-beta-induced matrix protein betaig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose
    Suk Hee Lee
    Cell and Matrix Biology, National Research Laboratory, Kyungpook National University, Taegu, Korea
    Kidney Int 64:1012-21. 2003
    ..TGF-beta is believed to be involved in the development of diabetic nephropathy and thus we have assessed the possibility that betaig-h3 may be a downstream molecule in this pathogenic process...
  11. doi request reprint The role of 70-kDa heat shock protein in dDAVP-induced AQP2 trafficking in kidney collecting duct cells
    Eui Jung Park
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, South Korea
    Am J Physiol Renal Physiol 304:F958-71. 2013
    ..The results suggest that Hsp70 is likely to play a role in AQP2 trafficking to the apical plasma membrane, partly through affecting AQP2 phosphorylation at Ser(256) and cell viability...
  12. doi request reprint E3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawal
    Yu Jung Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    Am J Physiol Renal Physiol 301:F883-96. 2011
    ..Taken together, identified E3s could be involved in the degradation of proteins associated with vasopressin-induced urine concentration...
  13. ncbi request reprint Increased AQP2 targeting in primary cultured IMCD cells in response to angiotensin II through AT1 receptor
    Yu Jung Lee
    Dept of Biochemistry and Cell Biology, School of Medicine, Kyungpook National Univ, Dongin dong 101, Taegu 700 422, Korea
    Am J Physiol Renal Physiol 292:F340-50. 2007
    ..In conclusion, ANG II plays a role in the regulation of AQP2 targeting to the plasma membrane in IMCD cells through AT(1) receptor activation and potentiates the effect of dDAVP on AQP2 plasma membrane targeting...
  14. doi request reprint Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation
    Hyo Young Kim
    Dept of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Dongin dong 101, Taegu 700 422, South Korea
    Am J Physiol Renal Physiol 301:F151-61. 2011
    ....
  15. doi request reprint Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis
    Ji Young Choi
    Division of Nephrology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
    Nephrol Dial Transplant 26:1304-13. 2011
    ....
  16. ncbi request reprint Targeting bladder tumor cells in vivo and in the urine with a peptide identified by phage display
    Seung Min Lee
    Department of Biochemistry, School of Medicine, Kyungpook National University, 101 Dongin dong, Jung Gu, Daegu 700 421, Korea
    Mol Cancer Res 5:11-9. 2007
    ..The CSNRDARRC peptide may be useful as a targeting moiety for selective delivery of therapeutics and as a diagnostic probe for the detection of bladder cancer...
  17. doi request reprint Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy
    Pyong Gon Moon
    Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea
    Proteomics 11:2459-75. 2011
    ..Taken together, this study showed the possibility of identifying biomarker candidates for human urinary diseases using urinary exosomes and might help to understand the pathophysiology of early IgAN and TBMN at the protein level...
  18. doi request reprint Metabonomic analysis of serum metabolites in kidney transplant recipients with cyclosporine A- or tacrolimus-based immunosuppression
    Chan Duck Kim
    Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
    Transplantation 90:748-56. 2010
    ....
  19. doi request reprint Regulation of AQP4 protein expression in rat brain astrocytes: role of P2X7 receptor activation
    MoonHee Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Dongin dong 101, Taegu 700 422, South Korea
    Brain Res 1195:1-11. 2008
    ....
  20. doi request reprint A novel method of ligand peptidomics to identify peptide ligands binding to AQP2-expressing plasma membranes and intracellular vesicles of rat kidney
    Yu Jung Lee
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea
    Am J Physiol Renal Physiol 295:F300-9. 2008
    ..Library analyses identified proteins having homologous motifs, which need to be examined for involvement in AQP2 trafficking and regulation...
  21. doi request reprint AQP5 expression predicts survival in patients with early breast cancer
    Soo Jung Lee
    Department of Oncology and Hematology, Kyungpook National University Medical Center, Kyungpook National University School of Medicine, Daegu, Korea
    Ann Surg Oncol 21:375-83. 2014
    ..Accordingly, we analyzed the prognostic impact of AQP5 expression in a large number of patients with early breast cancer (EBC)...
  22. ncbi request reprint Expression of the Na+-HCO3- cotransporter and its role in pHi regulation in guinea pig salivary glands
    Jingchao Li
    Department of Physiology, College of Dentistry, Seoul National University and Dental Research Institute, Seoul, Korea
    Am J Physiol Gastrointest Liver Physiol 291:G1031-40. 2006
    ..We conclude that NBC1 is functionally expressed and plays a role in pH(i) regulation in guinea pig salivary glands but that its localization and role are different depending on the type of salivary glands...
  23. pmc Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury
    Wook Young Baek
    Cell and Matrix Research Institute, Kyungpook National University, Daegu, Korea
    PLoS ONE 8:e69859. 2013
    ..This study suggests that the maintenance of Osx expression in bone is important in terms of preventing the onset of an inflammatory-prone state. ..
  24. doi request reprint Proteomic profiling of endothelial cells in human lung cancer
    Hye Jeong Park
    Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu, Korea
    J Proteome Res 7:1138-50. 2008
    ..Further ongoing analysis of these 16 candidate proteins will determine their potential applicability to NSCLC-specific diagnosis and therapeutics...
  25. ncbi request reprint Erythropoietin decreases renal fibrosis in mice with ureteral obstruction: role of inhibiting TGF-beta-induced epithelial-to-mesenchymal transition
    Sun Hee Park
    Division of Nephrology and Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
    J Am Soc Nephrol 18:1497-507. 2007
    ..It is suggested that the renoprotective effects of rhEPO could be mediated, at least partly, by inhibition of TGF-beta1-induced EMT...
  26. doi request reprint Metabolic profiling of kidney and urine in rats with lithium-induced nephrogenic diabetes insipidus by (1)H-NMR-based metabonomics
    Geum Sook Hwang
    Joint Bioanalytical Research Team, Korea Basic Science Institute, Seoul, Korea
    Am J Physiol Renal Physiol 298:F461-70. 2010
    ..Taken together, metabonomics of kidney tissue and urine based on (1)H-NMR spectroscopy could provide insight into the effects of Li-induced renal effects and cell injury...