Jae Sung Bae

Summary

Affiliation: Kyungpook National University
Country: Korea

Publications

  1. ncbi Adipose tissue-derived stem cells rescue Purkinje neurons and alleviate inflammatory responses in Niemann-Pick disease type C mice
    Jae Sung Bae
    Department of Physiology, Cell and Matrix Research Institute, BSEI, World Class University Program, School of Medicine, Kyungpook National University, Daegu, Korea
    Cell Tissue Res 340:357-69. 2010
  2. ncbi The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
    Hyun Ju Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, South Korea
    Neurosci Lett 481:30-5. 2010
  3. ncbi Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation
    Hyun Ju Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Neurobiol Aging 33:588-602. 2012
  4. ncbi Human umbilical cord blood-derived mesenchymal stem cells improve neurological abnormalities of Niemann-Pick type C mouse by modulation of neuroinflammatory condition
    Hyun Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Korea
    J Vet Med Sci 72:709-17. 2010
  5. ncbi Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann-Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate
    Hyun Lee
    Stem Cell Neuroplasticity Research Group, Daegu, Korea
    Stem Cells 28:821-31. 2010
  6. ncbi Intracerebellar transplantation of neural stem cells into mice with neurodegeneration improves neuronal networks with functional synaptic transmission
    Ji Min Lee
    Stem Cell Neuroplasticity Research Group, Department of Laboratory Animal Medicine, Kyungpook National University, Daegu, Korea
    J Vet Med Sci 72:999-1009. 2010
  7. ncbi Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration
    Jae Sung Bae
    Departments of Physiology, College of Medicine, Kyungpook National University, Korea
    Stem Cells 25:1307-16. 2007
  8. ncbi Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Stem Cells 28:329-43. 2010
  9. ncbi Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid β ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, South Korea
    Stem Cells 30:1544-55. 2012
  10. ncbi Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1α in an Alzheimer's disease mouse model
    Ji woong Shin
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Stem Cells 29:1075-89. 2011

Collaborators

  • Yong Chul Bae
  • Shogo Endo
  • Toshiro Sakamoto
  • Dong Ho Youn
  • Jong Kil Lee
  • Hee Kyung Jin
  • Woo Kie Min
  • Hyun Lee
  • Hyun Ju Lee
  • Edward H Schuchman
  • Ji woong Shin
  • Janet E Carter
  • So Young Chun
  • Tae Gyun Kwon
  • Bum Soo Kim
  • Bae Jin Kim
  • Byung Chul Park
  • In Ho Jeon
  • Thoudam Debraj Singh
  • Ji Min Lee
  • Wonil Oh
  • Byoung Hee Lee
  • Jun Gyo Suh
  • Yoon Sun Yang
  • James J Yoo
  • Jin Young Im
  • Shay Soker
  • Hyun Ju Lim
  • Jong Wook Chang
  • Ho Yun Chung
  • Anthony Atala
  • Chang Wug Oh
  • Won Ju Jeong
  • Jeong Eun Lee
  • Chang Hyun Cho
  • Hwan Seong Cho
  • Hyun Joo Lee
  • Min Jung Son
  • Rang Woon Park
  • Seung Yoon Park
  • In San Kim
  • Xingxuan He
  • Eui Kyun Park
  • Youngeun Yun
  • Shin Yoon Kim

Detail Information

Publications17

  1. ncbi Adipose tissue-derived stem cells rescue Purkinje neurons and alleviate inflammatory responses in Niemann-Pick disease type C mice
    Jae Sung Bae
    Department of Physiology, Cell and Matrix Research Institute, BSEI, World Class University Program, School of Medicine, Kyungpook National University, Daegu, Korea
    Cell Tissue Res 340:357-69. 2010
    ....
  2. ncbi The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
    Hyun Ju Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, South Korea
    Neurosci Lett 481:30-5. 2010
    ..Interestingly, hUCB-MSCs treated AD mice demonstrated cognitive rescue with restoration of learning/memory function. These data suggest that hUCB-MSCs warrant further investigation as a potential therapeutic agent in AD...
  3. ncbi Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation
    Hyun Ju Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Neurobiol Aging 33:588-602. 2012
    ....
  4. ncbi Human umbilical cord blood-derived mesenchymal stem cells improve neurological abnormalities of Niemann-Pick type C mouse by modulation of neuroinflammatory condition
    Hyun Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Korea
    J Vet Med Sci 72:709-17. 2010
    ..This study provides the first evidence that hUCB-MSCs can improve neurological symptoms in NP-C disease, suggesting it as a potential therapeutic agent against neurodegenerative diseases...
  5. ncbi Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann-Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate
    Hyun Lee
    Stem Cell Neuroplasticity Research Group, Daegu, Korea
    Stem Cells 28:821-31. 2010
    ..These effects suggest that BM-MSCs modulate sphingolipid metabolism of endogenous NP-C PNs, resulting in their survival and improved clinical outcome in mice...
  6. ncbi Intracerebellar transplantation of neural stem cells into mice with neurodegeneration improves neuronal networks with functional synaptic transmission
    Ji Min Lee
    Stem Cell Neuroplasticity Research Group, Department of Laboratory Animal Medicine, Kyungpook National University, Daegu, Korea
    J Vet Med Sci 72:999-1009. 2010
    ..These findings suggest that NSC, MHP36 transplantation may have therapeutic effects in the treatment of NP-C and other neurodegenerative diseases...
  7. ncbi Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration
    Jae Sung Bae
    Departments of Physiology, College of Medicine, Kyungpook National University, Korea
    Stem Cells 25:1307-16. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  8. ncbi Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Stem Cells 28:329-43. 2010
    ..These results demonstrate that BM-MSCs are a potential new therapeutic agent for AD...
  9. ncbi Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid β ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, South Korea
    Stem Cells 30:1544-55. 2012
    ..The recruitment of the alternative microglia into the brain is driven by CCL5 secretion from the transplanted BM-MSCs, which itself is induced by Aβ deposition in the AD brain...
  10. ncbi Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1α in an Alzheimer's disease mouse model
    Ji woong Shin
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    Stem Cells 29:1075-89. 2011
    ..This approach warrants further investigation as a potential therapeutic option for the treatment of AD patients in the future...
  11. ncbi Proliferation and osteoblastic differentiation of bone marrow stem cells: comparison of vertebral body and iliac crest
    Woo Kie Min
    Department of Orthopedic Surgery, School of Medicine, Kyungpook National University, 50 Samduk 2 Ga, Jung Gu, Daegu 700 712, Korea
    Eur Spine J 19:1753-60. 2010
    ..Based on these findings, we suggest that BMSCs from VB would be comparable candidates for osseous graft supplementation especially in spinal fusion procedures...
  12. ncbi Human amniotic fluid stem cell injection therapy for urethral sphincter regeneration in an animal model
    Bum Soo Kim
    Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea
    BMC Med 10:94. 2012
    ..Recently, human amniotic fluid stem cells (hAFSCs) have been proposed as an ideal cell therapy source. In this study, we investigated whether periurethral injection of hAFSCs can restore urethral sphincter competency in a mouse model...
  13. ncbi Specific labeling of neurogenic, endothelial, and myogenic differentiated cells derived from human amniotic fluid stem cells with silica-coated magnetic nanoparticles
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    J Vet Med Sci 74:969-75. 2012
    ..These results suggest that the fluorescent dye incorporated MNPs@SiO2 are a useful tool for the cell labeling and in vivo tracking of differentiated cells derived from hAFSCs...
  14. ncbi Reliability of Triggered EMG for Prediction of Safety during Pedicle Screw Placement in Adolescent Idiopathic Scoliosis Surgery
    Woo Kie Min
    Department of Orthopaedic Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea
    Asian Spine J 5:51-8. 2011
    ..We performed a prospective study to evaluate the reliability of using triggered electromyography (EMG) for predicting pedicle wall breakthrough during the placement of pedicle screw in adolescent idiopathic scoliosis surgery...
  15. ncbi MEGF10 functions as a receptor for the uptake of amyloid-β
    Thoudam Debraj Singh
    Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea
    FEBS Lett 584:3936-42. 2010
    ..Thus, the identification of the MEGF10 as a functional receptor that mediates the uptake of amyloid-β peptide will help elucidate the molecular mechanisms of amlyoid-β clearance in Alzheimer's disease...
  16. ncbi Bone marrow-derived mesenchymal stem cells improve the functioning of neurotrophic factors in a mouse model of diabetic neuropathy
    Bae Jin Kim
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Republic of Korea
    Lab Anim Res 27:171-6. 2011
    ..Also, BM-MSCs ameliorated nerve conduction velocity in streptozotocin-treated mice. These results may help to elucidate the mechanism by which BM-MSCs function as a cell therapy agent in diabetic neuropathy...
  17. ncbi Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model
    Jong Kil Lee
    Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, South Korea
    Neurosci Lett 450:136-41. 2009
    ..This study provides evidence that BM-MSCs can promote the reduction of Abeta through the microglial activation in this acutely induced AD brain, suggesting a potential therapeutic agent against AD...