Hyun Ju Moon

Summary

Affiliation: Korea Food and Drug Administration
Country: Korea

Publications

  1. ncbi request reprint Gestational exposure to nonylphenol causes precocious mammary gland development in female rat offspring
    Hyun Ju Moon
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 53:333-44. 2007
  2. pmc Lactational coumestrol exposure increases ovarian apoptosis in adult rats
    Hyun Ju Moon
    Reproductive and Developmental Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 194 Tongil ro, Eunpyung Gu, Seoul 122 704, South Korea
    Arch Toxicol 83:601-8. 2009
  3. doi request reprint OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals
    Hyun Ju Moon
    National Institute of Toxicological Research, Korea Food and Drug Administration, 194 Tongil ro, Eunpyung Gu, Seoul 122 704, Korea
    J Appl Toxicol 29:350-5. 2009
  4. ncbi request reprint OECD validation of the rodent Hershberger assay using three reference chemicals; 17alpha-methyltestosterone, procymidone, and p,p'-DDE
    Jae Ho Shin
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, South Korea
    Arch Toxicol 81:309-18. 2007
  5. ncbi request reprint Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the "Enhanced OECD Test Guideline No. 407" to detect endocrine effects
    Jae Ho Shin
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul 122 704, Korea
    Arch Toxicol 80:547-54. 2006
  6. ncbi request reprint Comparative estrogenic effects of p-nonylphenol by 3-day uterotrophic assay and female pubertal onset assay
    Hyung Sik Kim
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong, Eunpyung Ku, Seoul 122 704, South Korea
    Reprod Toxicol 16:259-68. 2002
  7. ncbi request reprint Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay
    Il Hyun Kang
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong, Eunpyung Ku, Seoul 122 704, South Korea
    Toxicology 199:145-59. 2004
  8. ncbi request reprint Repeated 28-day oral toxicity study of ketoconazole in rats based on the draft protocol for the "Enhanced OECD Test Guideline No. 407" to detect endocrine effects
    Jae Ho Shin
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul 122 704, Korea
    Arch Toxicol 80:797-803. 2006
  9. ncbi request reprint Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide
    Hyung Sik Kim
    National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong Eunpyung gu, Seoul 122 704, Korea
    Toxicol Sci 67:52-62. 2002
  10. ncbi request reprint Calbindin-D9k mRNA expression in the rat uterus following exposure to methoxychlor: a comparison of oral and subcutaneous exposure
    Jae Ho Shin
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 53:179-88. 2007

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Gestational exposure to nonylphenol causes precocious mammary gland development in female rat offspring
    Hyun Ju Moon
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 53:333-44. 2007
    ..Exposure to them during the critical period of epithelial outgrowth altered the receptor levels of mammary progesterone and prolactin and might contribute to the differences in the mammary morphology at PND 41...
  2. pmc Lactational coumestrol exposure increases ovarian apoptosis in adult rats
    Hyun Ju Moon
    Reproductive and Developmental Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 194 Tongil ro, Eunpyung Gu, Seoul 122 704, South Korea
    Arch Toxicol 83:601-8. 2009
    ..These results suggest new sights into the effect of lactational exposure to COU on the female reproductive health...
  3. doi request reprint OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals
    Hyun Ju Moon
    National Institute of Toxicological Research, Korea Food and Drug Administration, 194 Tongil ro, Eunpyung Gu, Seoul 122 704, Korea
    J Appl Toxicol 29:350-5. 2009
    ..These results suggest the OECD Hershberger assay to be a reliable screening method for detecting androgen agonists and antagonists...
  4. ncbi request reprint OECD validation of the rodent Hershberger assay using three reference chemicals; 17alpha-methyltestosterone, procymidone, and p,p'-DDE
    Jae Ho Shin
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, South Korea
    Arch Toxicol 81:309-18. 2007
    ..4 mg/kg/day) subcutaneously. Our data strongly suggested that the current protocol of OECD Hershberger assay (phase-2) should be used as a reliable method for the detection of endocrine related toxicity of other chemicals...
  5. ncbi request reprint Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the "Enhanced OECD Test Guideline No. 407" to detect endocrine effects
    Jae Ho Shin
    Endocrine Toxicology Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul 122 704, Korea
    Arch Toxicol 80:547-54. 2006
    ....
  6. ncbi request reprint Comparative estrogenic effects of p-nonylphenol by 3-day uterotrophic assay and female pubertal onset assay
    Hyung Sik Kim
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong, Eunpyung Ku, Seoul 122 704, South Korea
    Reprod Toxicol 16:259-68. 2002
    ..We therefore suggest that the female pubertal onset assay may be used as a sensitive testing method to detect environmental agents with weak estrogenic activity, but requires further research...
  7. ncbi request reprint Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay
    Il Hyun Kang
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong, Eunpyung Ku, Seoul 122 704, South Korea
    Toxicology 199:145-59. 2004
    ..We conclude that the 10-day Hershberger assay is a sensitive method for detecting potential anti-androgenic compounds...
  8. ncbi request reprint Repeated 28-day oral toxicity study of ketoconazole in rats based on the draft protocol for the "Enhanced OECD Test Guideline No. 407" to detect endocrine effects
    Jae Ho Shin
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul 122 704, Korea
    Arch Toxicol 80:797-803. 2006
    ....
  9. ncbi request reprint Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide
    Hyung Sik Kim
    National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbun dong Eunpyung gu, Seoul 122 704, Korea
    Toxicol Sci 67:52-62. 2002
    ..Moreover, additional data on other compounds with weak endocrine disrupting activity will be required to further characterize the sensitivity of the female pubertal assay...
  10. ncbi request reprint Calbindin-D9k mRNA expression in the rat uterus following exposure to methoxychlor: a comparison of oral and subcutaneous exposure
    Jae Ho Shin
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 53:179-88. 2007
    ....
  11. ncbi request reprint Pyrethroid insecticides, fenvalerate and permethrin, inhibit progesterone-induced alkaline phosphatase activity in T47D human breast cancer cells
    In Young Kim
    Department of Toxicology, National Institute of Toxicological Research, Seoul, Korea
    J Toxicol Environ Health A 68:2175-86. 2005
    ..Our data indicate that fenvalerate and permethrin exhibit antiprogestagenic activity in T47D human breast cancer cells...
  12. ncbi request reprint Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays
    In Young Kim
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 50:245-55. 2004
    ..These results suggest that certain pyrethroid insecticides may be considered to be estrogen-like chemicals that act through pathways other than direct ER binding, and may function as endocrine modulators in both wildlife and humans...
  13. ncbi request reprint Effects of flutamide on puberty in male rats: an evaluation of the protocol for the assessment of pubertal development and thyroid function
    Jae Ho Shin
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul
    J Toxicol Environ Health A 65:433-45. 2002
    ..Thus, this assay might be used as an alternative for screening antiandrogenic activities of chemicals...