Min Soo Lee

Summary

Affiliation: Korea University
Country: Korea

Publications

  1. ncbi request reprint Serotonin transporter promoter gene polymorphism and long-term outcome of antidepressant treatment
    Min Soo Lee
    Department of Psychiatry, Anam Hospital, Korea University College of Medicine, Sungbuk Ku, Seoul
    Psychiatr Genet 14:111-5. 2004
  2. ncbi request reprint Comparison of efficacy and safety of milnacipran and fluoxetine in Korean patients with major depression
    Min Soo Lee
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    Curr Med Res Opin 21:1369-75. 2005
  3. pmc Development and validation of a screening scale for depression in Korea: the lee and rhee depression scale
    Seon Hee Hwang
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    Psychiatry Investig 9:36-44. 2012
  4. pmc No Association between Serotonin Receptor 2C-759C/T Polymorphism and Weight Change or Treatment Response to Mirtazapine in Korean Depressive Patients
    Hwa Young Lee
    Department of Psychiatry, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea
    Psychiatry Investig 10:190-5. 2013
  5. ncbi request reprint Role of genetic polymorphisms related to neurotransmitters and cytochrome P-450 enzymes in response to antidepressants
    Min Soo Lee
    Depression Center, Clinical Research Center for Depression, Institute of Human Behavior and Genes, College of Medicine, Korea University, Seoul, Korea
    Drugs Today (Barc) 43:569-81. 2007
  6. ncbi request reprint No association between dopamine D4 receptor gene -521 C/T polymorphism and tardive dyskinesia in schizophrenia
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Neuropsychobiology 55:47-51. 2007
  7. ncbi request reprint G-protein beta3 subunit C825T polymorphism tends to be associated with seasonal variation in young male college students
    Heon Jeong Lee
    Department of Psychiatry, Anam Hospital, Korea University College of Medicine, Anam Dong, Seongbuk gu, Seoul 136 705, Korea
    Neuropsychobiology 52:135-9. 2005
  8. ncbi request reprint Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 32:160-3. 2008
  9. ncbi request reprint Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder
    Myoung Jin Choi
    Depression Center, Korea University, Seoul, Republic of Korea
    Brain Res 1118:176-82. 2006
  10. ncbi request reprint Association between the catechol O-methyltransferase Val108/158Met polymorphism and alexithymia
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea
    Neuropsychobiology 52:151-4. 2005

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Serotonin transporter promoter gene polymorphism and long-term outcome of antidepressant treatment
    Min Soo Lee
    Department of Psychiatry, Anam Hospital, Korea University College of Medicine, Sungbuk Ku, Seoul
    Psychiatr Genet 14:111-5. 2004
    ..This study investigates the relationship between the serotonin transporter linked polymorphic region (5-HTTLPR) and the long-term outcome of antidepressant treatment...
  2. ncbi request reprint Comparison of efficacy and safety of milnacipran and fluoxetine in Korean patients with major depression
    Min Soo Lee
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    Curr Med Res Opin 21:1369-75. 2005
    ..To compare efficacy and safety of milnacipran and fluoxetine in a population of Korean patients with major depression...
  3. pmc Development and validation of a screening scale for depression in Korea: the lee and rhee depression scale
    Seon Hee Hwang
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    Psychiatry Investig 9:36-44. 2012
    ..We also assessed the validity, reliability, and diagnostic utility of this scale (Lee and Rhee Depression Scale; LRDS)...
  4. pmc No Association between Serotonin Receptor 2C-759C/T Polymorphism and Weight Change or Treatment Response to Mirtazapine in Korean Depressive Patients
    Hwa Young Lee
    Department of Psychiatry, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea
    Psychiatry Investig 10:190-5. 2013
    ..We sought to determine whether the 5-HTR 2C receptor -759C/T polymorphism was associated with weight gain and treatment response to mirtazapine in major depressive disorder (MDD) patients...
  5. ncbi request reprint Role of genetic polymorphisms related to neurotransmitters and cytochrome P-450 enzymes in response to antidepressants
    Min Soo Lee
    Depression Center, Clinical Research Center for Depression, Institute of Human Behavior and Genes, College of Medicine, Korea University, Seoul, Korea
    Drugs Today (Barc) 43:569-81. 2007
    ..Both pharmacokinetic and pharmacodynamic change can affect the efficacy and side effects of antidepressants...
  6. ncbi request reprint No association between dopamine D4 receptor gene -521 C/T polymorphism and tardive dyskinesia in schizophrenia
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Neuropsychobiology 55:47-51. 2007
    ..Within the limitations imposed by the size of the clinical sample, these findings suggest that the DRD4 -521 C/T SNP does not contribute significantly to the risk for TD...
  7. ncbi request reprint G-protein beta3 subunit C825T polymorphism tends to be associated with seasonal variation in young male college students
    Heon Jeong Lee
    Department of Psychiatry, Anam Hospital, Korea University College of Medicine, Anam Dong, Seongbuk gu, Seoul 136 705, Korea
    Neuropsychobiology 52:135-9. 2005
    ..These results suggest that GNB3 C825T polymorphism tends to be related to seasonal variation in mood and behavior in the normal population...
  8. ncbi request reprint Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 32:160-3. 2008
    ..046). This finding supports the presence of a relationship between the -2548A/G SNP of the leptin gene and weight gain in Korean schizophrenic patients receiving olanzapine treatment...
  9. ncbi request reprint Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder
    Myoung Jin Choi
    Depression Center, Korea University, Seoul, Republic of Korea
    Brain Res 1118:176-82. 2006
    ..Moreover, the Val66Met polymorphism was correlated with improvements in core, activity, and psychic anxiety symptoms...
  10. ncbi request reprint Association between the catechol O-methyltransferase Val108/158Met polymorphism and alexithymia
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea
    Neuropsychobiology 52:151-4. 2005
    ..However, there was no significant relationship between the 5-HTTLPR genotype and TAS-20 scores. This indicates a possible association between the COMT Val108/158Met gene polymorphism and alexithymia...
  11. ncbi request reprint Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene
    Myoung Jin Choi
    Department of Psychiatry, Korea University College of Medicine, Seoul, Korea
    Neuropsychobiology 49:38-41. 2004
    ..18, p = 0.001; OR = 2.46, 95% CI 1.40-4.32). Our results support the hypothesis that the -1438A/G polymorphism of the promoter region of the 5-HTR2A gene is associated with MDD patients in a Korean population...
  12. doi request reprint No association between the brain-derived neurotrophic factor gene Val66Met polymorphism and tardive dyskinesia in schizophrenic patients
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, and Kangbuk Samsung Hospital, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 32:1545-8. 2008
    ..This study investigated whether the brain-derived neurotrophic factor (BDNF) gene Val66Met single-nucleotide polymorphism (SNP) is associated with antipsychotic-induced tardive dyskinesia (TD) in schizophrenia...
  13. ncbi request reprint Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene is not associated with tardive dyskinesia in schizophrenia
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Neuropsychobiology 57:22-5. 2008
    ..This study investigated whether the catechol-O-methyltransferase (COMT) gene V158M single-nucleotide polymorphism (SNP) influences susceptibility to tardive dyskinesia (TD)...
  14. ncbi request reprint Association between norepinephrine transporter gene polymorphism and major depression
    Seung Ho Ryu
    Department of Psychiatry, Konkuk University College of Medicine, Seoul, Korea
    Neuropsychobiology 49:174-7. 2004
    ..019). This result suggests that the T-182C polymorphism in the NET gene might be associated with major depression...
  15. ncbi request reprint Association study between antipsychotics- induced restless legs syndrome and polymorphisms of dopamine D1, D2, D3, and D4 receptor genes in schizophrenia
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Neuropsychobiology 57:49-54. 2008
    ..This study investigated whether single-nucleotide polymorphisms in the genes of dopamine receptors DRD1, DRD2, DRD3 and DRD4 are associated with antipsychotics-induced RLS in schizophrenia...
  16. doi request reprint DRD2/ANKK1 TaqI A polymorphism affects corticostriatal activity in response to negative affective facial stimuli
    Byeong Taek Lee
    Office of Admissions, Seoul National University, Seoul, Republic of Korea
    Behav Brain Res 223:36-41. 2011
    ..Furthermore, molecular heterosis at the TaqI polymorphism of DRD2/ANKK1 may play an important role in affective regulation by corticostriatal pathway...
  17. ncbi request reprint Predictors of 12-week remission in a nationwide cohort of people with depressive disorders: the CRESCEND study
    Jae Min Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    Hum Psychopharmacol 26:41-50. 2011
    ..To estimate the 12-week remission rate of patients with depressive disorders and predictors of this in a naturalistic clinical setting in South Korea...
  18. ncbi request reprint Serotonin receptor 2A gene polymorphism (-1438A/G) and short-term treatment response to citalopram
    Myoung Jin Choi
    Pharmacogenomic Research Center for Psychotropic Drugs, Korea University, Seoul, Korea
    Neuropsychobiology 52:155-62. 2005
    ....
  19. ncbi request reprint No evidence for an association between G protein beta3 subunit gene C825T polymorphism and tardive dyskinesia in schizophrenia
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, Korea
    Hum Psychopharmacol 22:501-4. 2007
    ..Tardive dyskinesia (TD) is a long-term adverse effect of antipsychotic. We evaluated candidate functional polymorphism of the G protein beta3 subunit (GNB3) gene for association with drug-induced TD in the Korean schizophrenic patients...
  20. doi request reprint Trial of aripiprazole in the treatment of first-episode schizophrenia
    Hwa Young Lee
    Clinical Research Center for Depression, Institute of Human Behavior and Gene, Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    Psychiatry Clin Neurosci 64:38-43. 2010
    ..The aim of the present study was to investigate therapeutic efficacy and tolerability of aripiprazole in patients with first-episode schizophrenia...
  21. ncbi request reprint Stress-induced decrease of granule cell proliferation in adult rat hippocampus: assessment of granule cell proliferation using high doses of bromodeoxyuridine before and after restraint stress
    Sung Jin Kim
    Department of Pharmacology, Korea University College of Medicine, Seoul 136 705, Korea
    Mol Cells 19:74-80. 2005
    ..These observations suggest that restraint stress decreases granule cell proliferation, and that this may be influenced by the extent and duration of plasma corticosterone increases rather than by changes in the availability of BrdU...
  22. doi request reprint Response to antidepressants in major depressive disorder with melancholic features: the CRESCEND study
    Su Jin Yang
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Affect Disord 144:42-50. 2013
    ..This study aimed to determine whether major depressive disorders with melancholic and without melancholic features differ with respect to their responses to treatment with antidepressants...
  23. doi request reprint Physical comorbidity and 12-week treatment outcomes in Korean patients with depressive disorders: the CRESCEND study
    Jae Min Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Psychosom Res 71:311-8. 2011
    ..This study aimed to compare treatment outcomes between people with depressive disorder with and without comorbid physical disorders...
  24. ncbi request reprint Impact of childhood adversity on the course and suicidality of depressive disorders: the CRESCEND study
    Sung Wan Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea
    Depress Anxiety 30:965-74. 2013
    ..The impact of childhood adversity persists across the life course. This study aimed to investigate the associations of childhood adversity with the course, suicidality, and treatment outcomes of depressive disorders...
  25. ncbi request reprint Association between the tryptophan hydroxylase-1 gene A218C polymorphism and citalopram antidepressant response in a Korean population
    Byung Joo Ham
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:104-7. 2007
    ..Our results suggest that the A218C polymorphism of the TPH1 gene serves as a modulator of antidepressant activity, especially in terms of treatment remission...
  26. ncbi request reprint Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder
    Rhee Hun Kang
    Depression Center, Korea University, Seoul, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1317-21. 2007
    ..These results support our hypothesis that the response to noradrenergic and specific serotonergic antidepressants is significantly associated with the 5-HTTLPR polymorphism...
  27. ncbi request reprint Characteristics and clinical correlates of restless legs syndrome in schizophrenia
    Seung Gul Kang
    Department of Psychiatry, Anam Hospital, Korea University College of Medicine, Anam Dong 5 Ga, Seongbuk gu, Seoul, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1078-83. 2007
    ..The purpose of this study was to establish the prevalence, characteristics, and clinical correlates of RLS in schizophrenic patients undergoing treatment with antipsychotics...
  28. ncbi request reprint D2 and D4 dopamine receptor gene polymorphisms and personality traits in a young Korean population
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, Korea
    Am J Med Genet B Neuropsychiatr Genet 121:44-9. 2003
    ....
  29. doi request reprint Stressful events, stress perception and treatment outcomes in patients with depressive disorders: the CRESCEND study
    Jae Min Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Affect Disord 133:528-36. 2011
    ..In a prospective naturalistic study of depression treatment we sought to investigate perceived stress as a predictor of 12-week antidepressant treatment outcome...
  30. ncbi request reprint Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus
    Kuem Ju Lee
    Graduate School of Biomedical Sciences, Korea University College of Medicine, Seoul 136 705, Korea
    Exp Mol Med 38:44-54. 2006
    ..These results raise the possibility that the survival of new-born cells may be suppressed in the presence of normal BDNF mRNA levels in GCL...
  31. ncbi request reprint Demonstration of decreased gray matter concentration in the midbrain encompassing the dorsal raphe nucleus and the limbic subcortical regions in major depressive disorder: an optimized voxel-based morphometry study
    Hwa Young Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    J Affect Disord 133:128-36. 2011
    ..However, the results of these studies are inconsistent, and relatively few studies have been conducted using voxel-based morphometry (VBM) to detect gray matter concentration (GMC) abnormalities in patients with MDD...
  32. doi request reprint Manganese superoxide dismutase gene Ala-9Val polymorphism might be related to the severity of abnormal involuntary movements in Korean schizophrenic patients
    Seung Gul Kang
    Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 32:1844-7. 2008
    ....
  33. ncbi request reprint No association between the tryptophan hydroxylase gene polymorphism and major depressive disorders and antidepressant response in a Korean population
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea
    Psychiatr Genet 15:299-301. 2005
    ..Results suggest that the A218C polymorphism of the TPH gene does not play a major role in pathogenesis in MDD and does not serve as a modulator of antidepressant activity...
  34. ncbi request reprint Relationship between G-protein beta-3 subunit C825T polymorphism and mirtazapine responses in Korean patients with major depression
    Rhee Hun Kang
    Depression Center, Korea University, Seoul, Korea
    Neuropsychobiology 56:1-5. 2007
    ..This study aimed to determine the relationship between the C825T polymorphism in the G-protein beta 3 subunit (GNB3) gene and the response to mirtazapine in a Korean population with major depressive disorder (MDD)...
  35. ncbi request reprint Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder
    Heon Jeong Lee
    Department of Psychiatry and Depression Center, Korea University College of Medicine, Seoul, Korea
    Depress Anxiety 21:135-9. 2005
    ..Further investigations are required into the influence of gene polymorphisms on the biological mechanisms of PTSD, its clinical expression, and its response to treatment...
  36. doi request reprint Long-term efficacy and safety of aripiprazole in patients with schizophrenia, schizophreniform disorder, or schizoaffective disorder: 26-week prospective study
    Jun Soo Kwon
    Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea
    Psychiatry Clin Neurosci 63:73-81. 2009
    ..The aim of the present study was therefore to investigate the long-term efficacy, safety and tolerability of aripiprazole in a large number of patients with schizophrenia, schizophreniform disorder, or schizoaffective disorder in Korea...
  37. ncbi request reprint Latency of auditory P300 correlates with self-control as measured by the Sixteen Personality Factor Questionnaire
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, Korea
    Psychiatry Clin Neurosci 59:418-24. 2005
    ..46, P = 0.044; and r = -0.72, P = 0.002, respectively). These results indicate that the personality traits of self-control, perfectionism, high superego, and reasoning are related to information processing in the brain...
  38. ncbi request reprint Does comorbid subthreshold anxiety predict treatment response in depression? Results from a naturalistic cohort study (the CRESCEND study)
    Ho Jun Seo
    Department of Psychiatry, St Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea Clinical Research Center for Depression, Seoul, Republic of Korea
    J Affect Disord 152:352-9. 2014
    ..To investigate whether the anxious depression defined as depression with clinically significant anxiety but not comorbid anxiety disorder predicts poor outcomes of depression treatment in naturalistic clinical setting...
  39. ncbi request reprint Effects of repeated tianeptine treatment on CRF mRNA expression in non-stressed and chronic mild stress-exposed rats
    Sung Jin Kim
    Department of Pharmacology, College of Medicine, Korea University, Seoul, South Korea
    Neuropharmacology 50:824-33. 2006
    ..In addition, these results suggest that repeated tianeptine treatment diminishes the basal activity of CRF neurons and reduces their sensitivity to stress...
  40. ncbi request reprint Effect of serotonin receptor 2A gene polymorphism on mirtazapine response in major depression
    Rhee Hun Kang
    Korea University, Seoul
    Int J Psychiatry Med 37:315-29. 2007
    ....
  41. doi request reprint Association between serotonin transporter-linked polymorphic region and escitalopram antidepressant treatment response in Korean patients with major depressive disorder
    Eun Soo Won
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Republic of Korea
    Neuropsychobiology 66:221-9. 2012
    ..The purpose of this study was to evaluate the association between 5-HTTLPR and clinical response to escitalopram treatment in Korean subjects with major depressive disorder...
  42. ncbi request reprint Impact of tryptophan hydroxylase 2 G-703T polymorphism on anger-related personality traits and orbitofrontal cortex
    Ho Kyoung Yoon
    Department of Psychiatry, Korea University, Seoul, South Korea
    Behav Brain Res 231:105-10. 2012
    ..The mechanism underlying the effect of the TPH2 gene on OFC abnormality, however, may be complex and may involve several processes related to anger expression...
  43. doi request reprint Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole
    Jun Soo Kwon
    Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
    Eur Neuropsychopharmacol 18:897-907. 2008
    ..The results suggest an association between the DRD2 Taq1A polymorphism status and the variation in the clinical response to aripiprazole...
  44. doi request reprint Factors associated with subjective quality of life in Korean patients with depressive disorders: the CRESCEND study
    Young Eun Jung
    Department of Psychiatry, The Catholic University College of Medicine, 62 Yeouido dong, Youngdeungpo gu, Seoul, 150 713, Republic of Korea
    Qual Life Res 21:967-74. 2012
    ..We aimed to assess subjective QOL in Korean patients with depression and explore the factors (sociodemographic characteristics and clinical features) associated with subjective QOL...
  45. ncbi request reprint Gender differences in 12-week antidepressant treatment outcomes for a naturalistic secondary care cohort: the CRESCEND study
    Su Jin Yang
    Department of Psychiatry, Chonnam National University Medical School, 5 Hak dong, Dong Gu, Gwangju, Republic of Korea
    Psychiatry Res 189:82-90. 2011
    ..Women were found to have better outcomes following antidepressant treatment than men, and postmenopausal women had a better response on anxiety symptoms with newer dual action antidepressants...
  46. doi request reprint Effects of reboxetine and citalopram pretreatment on changes in cocaine and amphetamine regulated transcript (CART) expression in rat brain induced by the forced swimming test
    Seungwoo Kang
    Department of Pharmacology and Division of Brain Korea 21 Biomedical Science, Korea University College of Medicine, Sungbuk Gu, Seoul, Republic of Korea
    Eur J Pharmacol 647:110-6. 2010
    ..These results suggest that inhibition of FST-induced increases in CART expression in the nucleus accumbens, central nucleus of the amygdala, and locus ceruleus may be a common mechanism of antidepressant effects during the FST...
  47. ncbi request reprint CLOCK gene 3111C/T polymorphism is not associated with seasonal variations in mood and behavior in Korean college students
    Jong Woo Paik
    Department of Psychiatry, Korea University College of Medicine, Seoul, Korea
    Psychiatry Clin Neurosci 61:124-6. 2007
    ..05). These findings suggest that the CLOCK polymorphism does not play a major role in susceptibility to seasonal variations in a Korean population...
  48. doi request reprint Association of the adrenergic alpha 2a receptor--1291C/G polymorphism with weight change and treatment response to mirtazapine in patients with major depressive disorder
    Hwa Young Lee
    Department of Psychiatry, College of Medicine, Korea University, Republic of Korea Depression Center, Korea University, Seoul, Republic of Korea
    Brain Res 1262:1-6. 2009
    ..Our objective was to determine whether the ADRA2A -1291C/G polymorphism is associated with weight gain and treatment response to mirtazapine in patients with major depressive disorder (MDD)...
  49. ncbi request reprint Doxapram increases corticotropin-releasing factor immunoreactivity and mRNA expression in the rat central nucleus of the amygdala
    Song hyen Choi
    Department of Pharmacology, Korea University College of Medicine, Sungbuk Gu, Anam Dong 5 Ga 126 1, Seoul 136 705, Republic of Korea
    Peptides 26:2246-51. 2005
    ..This increase in CRF-IR within the CeA might explain the doxapram-induced anxiety reaction...
  50. pmc Antidepressant prescribing patterns in Korea: results from the clinical research center for depression study
    Kyung Yeol Bae
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea
    Psychiatry Investig 8:234-44. 2011
    ....
  51. pmc Association between glucocorticoid receptor methylation and hippocampal subfields in major depressive disorder
    Kyoung Sae Na
    Department of Psychiatry, Gachon University Gil Medical Center, Incheon, Republic of Korea
    PLoS ONE 9:e85425. 2014
    ..We investigated the possible association between NR3C1 methylation and structural brain alterations in MDD in comparison with healthy controls...
  52. doi request reprint Improvement within 2 weeks and later treatment outcomes in patients with depressive disorders: the CRESCEND study
    Jae Min Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Affect Disord 129:183-90. 2011
    ....
  53. doi request reprint Neural substrates of affective face recognition in alexithymia: a functional magnetic resonance imaging study
    Byeong Taek Lee
    Office of Admissions, Seoul National University, Korea University, Seoul, Korea
    Neuropsychobiology 63:119-24. 2011
    ..Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear...
  54. ncbi request reprint Personality traits associated with suicidal behaviors in patients with depression: The CRESCEND study
    Ho Jun Seo
    Department of Psychiatry, St Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea Clinical Research Center for Depression, Seoul, Republic of Korea
    Compr Psychiatry 55:1085-92. 2014
    ..It is noteworthy that this result emerged after controlling for the effect of current mood state. ..
  55. ncbi request reprint Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients
    Sun Young Lee
    Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    J Psychosom Res 57:5-10. 2004
    ..We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD)...
  56. doi request reprint Decreased gray matter volume of the medial orbitofrontal cortex in panic disorder with agoraphobia: a preliminary study
    Kyoung Sae Na
    Department of Psychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 45:195-200. 2013
    ..Although recent neurobiological studies have suggested that fear conditioning and extinction are associated with PDA, no study has examined the possible structural abnormalities in patients with PDA...
  57. pmc Evidence-based, pharmacological treatment guideline for depression in Korea, revised edition
    Eunsoo Won
    Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
    J Korean Med Sci 29:468-84. 2014
    ..Therefore, the wide distribution of this guideline is recommended. ..
  58. doi request reprint Persistence and resolution of suicidal ideation during treatment of depression in patients with significant suicidality at the beginning of treatment: the CRESCEND study
    Ho Jun Seo
    Department of Psychiatry, St Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea Clinical Research Center for Depression, Seoul, Republic of Korea
    J Affect Disord 155:208-15. 2014
    ..We evaluated the course of suicidal ideation and associated factors for persistent suicidality in patients who entered treatment for depression with significant suicidal ideation...
  59. pmc G-protein beta3 Subunit Gene 825C/T Polymorphism Is Not Associated with Olanzapine-Induced Weight Gain in Korean Schizophrenic Patients
    Young Min Park
    Department of Psychiatry, Inje University College of Medicine, Goyang, Korea
    Psychiatry Investig 6:39-43. 2009
    ..A relationship between weight gain and the G protein beta3 subunit gene (GNB3) 825C/T polymorphism has been reported. We therefore examined this possible association in a Korean schizophrenic patient group receiving olanzapine treatment...
  60. pmc Efficacy and tolerability of aripiprazole: a 26-week switching study from oral antipsychotics
    Jung Sun Lee
    Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Psychiatry Investig 7:189-95. 2010
    ..To determine if the maintenance effectiveness and tolerability of aripiprazole demonstrated in a 12-week study were maintained in an extension phase (up to 26 weeks)...
  61. doi request reprint Relationship between a history of a suicide attempt and treatment outcomes in patients with depression
    Sung Wan Kim
    Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Clin Psychopharmacol 31:449-56. 2011
    ..Therefore, more intensive and longer-term treatment with particular ongoing clinical attention to risk is indicated in patients with these distinct, chronic, and severe forms of depression and ongoing high suicide risk...
  62. ncbi request reprint Reward dependence is related to norepinephrine transporter T-182C gene polymorphism in a Korean population
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea
    Psychiatr Genet 15:145-7. 2005
    ..Further studies are necessary with a larger number of homogeneous participants to confirm whether the norepinephrine transporter gene is related to personality traits...
  63. pmc The clinical research center for depression study: baseline characteristics of a korean long-term hospital-based observational collaborative prospective cohort study
    Tae Suk Kim
    Department of Psychiatry, The Catholic University of Korea School of Medicine, Seoul, Korea
    Psychiatry Investig 8:1-8. 2011
    ..In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort...
  64. doi request reprint Distinctive clinical characteristics and suicidal tendencies of patients with anxious depression
    Ho Jun Seo
    Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
    J Nerv Ment Dis 199:42-8. 2011
    ..The present findings that were drawn from detailed evaluation of suicidality strongly support previous results assessed only with the help of clinical reports. More attention should be paid to assess suicide risk in these patients...
  65. ncbi request reprint Effects of methylphenidate and bupropion on DHEA-S and cortisol plasma levels in attention-deficit hyperactivity disorder
    Moon Soo Lee
    Korea University Medical Center, Seoul, Korea
    Child Psychiatry Hum Dev 39:201-9. 2008
    ..DHEA-S levels increased from baseline to endpoint, but cortisol levels did not change significantly. This study suggests that both methylphenidate and bupropion increase plasma levels of DHEA-S in boys with ADHD...
  66. doi request reprint The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea
    Byeong Taek Lee
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    World J Biol Psychiatry 10:552-9. 2009
    ..The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB...
  67. doi request reprint Clinical characteristics of depressed patients with a history of suicide attempts: results from the CRESCEND study in South Korea
    Min Hyeon Park
    Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, South Korea
    J Nerv Ment Dis 198:748-54. 2010
    ..This unique tendency is probably related to the sociodemographic and cultural characteristics of South Korea...
  68. ncbi request reprint Low serum cholesterol is correlated to suicidality in a Korean sample
    Yong Ku Kim
    Department of Psychiatry, College of Medicine, Korea University, Ansan City, Kyunggi Province
    Acta Psychiatr Scand 105:141-8. 2002
    ..The aim of this study was to examine further the association between low total serum cholesterol and suicidal behaviour...
  69. ncbi request reprint MRP1 polymorphisms associated with citalopram response in patients with major depression
    Sung Hee Lee
    Department of Pharmacology and Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea
    J Clin Psychopharmacol 30:116-25. 2010
    ..4002G>A or c.5462T>A polymorphisms showed higher MRP1 mRNA levels in peripheral blood cells. These results suggest that MRP1 polymorphisms may be a predictive marker of citalopram treatment in major depression...
  70. doi request reprint Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients
    Rhee Hun Kang
    Departments of Psychiatry, Korea University College of Medicine, Seoul, Korea
    J Clin Psychopharmacol 29:272-7. 2009
    ..30 ng/mL per milligram, P = 0.005). In conclusion, both CYP2D6 and CYP3A5 genotypes affected plasma levels of RIS and 9-OH-RIS, whereas the active moiety levels were influenced only by the CYP3A5 genotype but not by the CYP2D6 genotype...
  71. doi request reprint Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression
    Kyu Man Han
    Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea
    J Affect Disord 155:42-8. 2014
    ..This study aimed to evaluate the differences in cortical thickness, cortical and subcortical volume, and white matter integrity between first episode, medication-naïve MDD patients and healthy controls...
  72. ncbi request reprint Allelic variants interaction of dopamine receptor D4 polymorphism correlate with personality traits in young Korean female population
    Heon Jeong Lee
    Department of Psychiatry, Korea University College of Medicine, Anam Hospital, 126 1, 5 Ka, Anam Dong, Sungbuk Ku, Seoul 136 705, Korea
    Am J Med Genet B Neuropsychiatr Genet 118:76-80. 2003
    ..When analyzed independently, however, the two different alleles of DRD4 polymorphisms, 48-bp VNTR and -521 C/T, there was no direct correlation with the personality traits...
  73. doi request reprint A 12-week, naturalistic switch study of the efficacy and tolerability of aripiprazole in stable outpatients with schizophrenia or schizoaffective disorder
    Chang Yoon Kim
    Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138 736, Korea
    Int Clin Psychopharmacol 24:181-8. 2009
    ..The majority of patients was successfully switched from other antipsychotics without serious symptom exacerbation or adverse events over a course of 12 weeks...
  74. pmc Lack of Association between Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphisms and Generalized Social Anxiety Disorder in Korean Population
    Jin Sung Park
    Department of Psychiatry, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Clin Psychopharmacol Neurosci 9:129-33. 2011
    ..We analyzed the association of the BDNF gene polymorphism, G196A (val66met), in the coding region of exon XIIIA in chromosome 11p13, and generalized social anxiety disorder (GSAD)...
  75. pmc The effect of initial duloxetine dosing strategy on nausea in korean patients with major depressive disorder
    Min Soo Lee
    Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea
    Psychiatry Investig 9:391-9. 2012
    ..To assess the relative severity of nausea in patients from Korea with major depressive disorder (MDD) who were treated with duloxetine at low (30 mg) or high (60 mg) doses, with or without food, for the first week of an 8 week treatment...
  76. ncbi request reprint Gender-specific molecular heterosis of dopamine D2 receptor gene (DRD2) for smoking in schizophrenia
    Hong Seock Lee
    Department of Psychiatry, College of Medicine, Korea University Hospital, Seoul, Korea
    Am J Med Genet 114:593-7. 2002
    ..They indicate the importance of heterosis and gender effects that should be taken into consideration for the association studies...
  77. ncbi request reprint International study on antidepressant prescription pattern at 20 teaching hospitals and major psychiatric institutions in East Asia: Analysis of 1898 cases from China, Japan, Korea, Singapore and Taiwan
    Naoki Uchida
    Fukuoka University College of Medicine, Fukuoka, Japan
    Psychiatry Clin Neurosci 61:522-8. 2007
    ..0% of all cases. At the time of the survey, only two SSRI medications were available in Japan. However, five types of SSRI were available and were often prescribed in Korea...
  78. ncbi request reprint Serotonergic genes and personality traits in the Korean population
    Byung Joo Ham
    Yong In Psychiatric Research Institute, Kyeonggi Province, 449 769, South Korea
    Neurosci Lett 354:2-5. 2004
    ..Further studies of polymorphisms of other genes and their interactions may clarify the complex relationship between personality and genes...
  79. ncbi request reprint Association between the 5-HT6 receptor C267T polymorphism and response to antidepressant treatment in major depressive disorder
    Seung Hwan Lee
    Department of Psychiatry, Inje University College of Medicine, Koyang, South Korea
    Psychiatry Clin Neurosci 59:140-5. 2005
    ..These findings imply that a 5-HT6 receptor polymorphism (C267T) is associated with treatment response in MDD...
  80. ncbi request reprint Could pharmacogenetics play a role as predictor in treatment of depressive disorders?
    Min Soo Lee
    World J Biol Psychiatry 8:2-3. 2007
  81. ncbi request reprint Valproate prevents MK801-induced changes in brain-derived neurotrophic factor mRNA in the rat brain
    Gye Sun Jeon
    Department of Pharmacology, Korea University College of Medicine, 5 Anam dong, Seoul 136 705, South Korea
    Eur J Pharmacol 545:142-6. 2006
    ..These results indicate that valproate pretreatment differentially affects the MK801-induced changes in BDNF expression in a region-selective manner...
  82. ncbi request reprint A preliminary survey of undergraduate education on depression in medical schools in the Asia Pacific region
    Min Soo Lee
    University Hospital, Korea University, South Korea
    Australas Psychiatry 12:S28-32. 2004
    ..To describe the undergraduate medical curricula pertaining to depression across the Asia Pacific region...
  83. ncbi request reprint Personality, dopamine receptor D4 exon III polymorphisms, and academic achievement in medical students
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    Neuropsychobiology 53:203-9. 2006
    ....